Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01865:Tspyl5'

178469

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tspyl5

Ensembl Gene

ENSMUSG00000038984

Gene Name

testis-specific protein, Y-encoded-like 5

Synonyms

E130308C19Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.135) question?

Stock #

IGL01865

Quality Score

Status

Chromosome

Chromosomal Location

33684021-33688029 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to T at 33687858 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Alanine to Glutamic Acid at position 29 (A29E)

Ref Sequence

ENSEMBL: ENSMUSP00000045542 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000042021]

AlphaFold

Q69ZB3

Predicted Effect

unknown
Transcript: ENSMUST00000042021
AA Change: A29E

SMART Domains

Protein: ENSMUSP00000045542
Gene: ENSMUSG00000038984
AA Change: A29E

Domain	Start	End	E-Value	Type
low complexity region	2	29	N/A	INTRINSIC
low complexity region	49	62	N/A	INTRINSIC
Pfam:NAP	238	378	1.9e-21	PFAM
low complexity region	379	395	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 45 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
9130023H24Rik	T	C	7: 127,836,107 (GRCm39)	H162R	probably damaging	Het
Adamts10	T	A	17: 33,772,140 (GRCm39)	M1096K	probably damaging	Het
Asap3	G	T	4: 135,963,715 (GRCm39)	C325F	probably damaging	Het
Atm	T	C	9: 53,372,302 (GRCm39)	E2160G	probably damaging	Het
Col4a1	G	A	8: 11,251,790 (GRCm39)		probably benign	Het
Ctdp1	C	T	18: 80,499,199 (GRCm39)	G248S	probably damaging	Het
Dcaf5	A	T	12: 80,386,088 (GRCm39)	D679E	probably benign	Het
Efcab2	C	A	1: 178,303,253 (GRCm39)	Y91*	probably null	Het
Eif3d	G	T	15: 77,851,546 (GRCm39)	T88K	probably benign	Het
Gapvd1	G	A	2: 34,585,515 (GRCm39)	A1049V	probably null	Het
Gm10717	C	T	9: 3,025,616 (GRCm39)	S67L	probably benign	Het
Gm10717	A	T	9: 3,026,287 (GRCm39)	Y195F	probably damaging	Het
Gm10718	A	T	9: 3,025,118 (GRCm39)	Y194F	probably benign	Het
Gm18856	T	A	13: 14,139,508 (GRCm39)		probably benign	Het
Gm21738	G	A	14: 19,416,979 (GRCm38)	S144L	probably benign	Het
Gm9991	A	G	1: 90,606,635 (GRCm39)		noncoding transcript	Het
Hapln1	T	C	13: 89,749,784 (GRCm39)	Y110H	probably damaging	Het
Htr1f	A	G	16: 64,746,282 (GRCm39)	Y337H	probably damaging	Het
Kirrel1	T	A	3: 86,993,731 (GRCm39)	S509C	probably damaging	Het
Limch1	A	T	5: 67,131,923 (GRCm39)	R138*	probably null	Het
Lypla1	A	C	1: 4,907,259 (GRCm39)	I108L	probably damaging	Het
Mc3r	A	G	2: 172,090,975 (GRCm39)	N66D	probably damaging	Het
Melk	T	A	4: 44,344,988 (GRCm39)	C373S	probably benign	Het
Myocd	C	A	11: 65,091,723 (GRCm39)	S73I	probably benign	Het
Nell2	A	G	15: 95,282,962 (GRCm39)	V360A	possibly damaging	Het
Npas4	G	A	19: 5,035,819 (GRCm39)	Q782*	probably null	Het
Or7a36	A	T	10: 78,820,512 (GRCm39)	D296V	possibly damaging	Het
Pdzd8	T	C	19: 59,288,077 (GRCm39)	K1108E	possibly damaging	Het
Per2	A	G	1: 91,349,239 (GRCm39)	I1044T	probably benign	Het
Pgm3	A	G	9: 86,437,371 (GRCm39)	F501S	possibly damaging	Het
Ppp1r3c	A	G	19: 36,711,578 (GRCm39)	V64A	probably benign	Het
Ptpn6	A	T	6: 124,709,428 (GRCm39)	I15N	probably damaging	Het
Pxk	T	C	14: 8,136,923 (GRCm38)	V148A	possibly damaging	Het
Rngtt	T	A	4: 33,325,157 (GRCm39)		probably benign	Het
Rtkn2	T	G	10: 67,871,705 (GRCm39)	S364R	probably benign	Het
Rtn1	A	C	12: 72,266,074 (GRCm39)	L167R	probably damaging	Het
Sp2	G	A	11: 96,851,868 (GRCm39)	T352I	probably damaging	Het
Tbc1d17	A	G	7: 44,492,113 (GRCm39)	M459T	possibly damaging	Het
Tbcd	T	A	11: 121,481,206 (GRCm39)	M694K	possibly damaging	Het
Tln2	G	A	9: 67,157,896 (GRCm39)	R1148*	probably null	Het
Trim27	T	C	13: 21,376,662 (GRCm39)	V294A	probably damaging	Het
Vmn2r129	C	T	4: 156,690,549 (GRCm39)		noncoding transcript	Het
Vrk2	C	T	11: 26,485,560 (GRCm39)	V143I	possibly damaging	Het
Zfp952	G	A	17: 33,221,791 (GRCm39)	R52Q	probably benign	Het
Zfp979	A	T	4: 147,699,774 (GRCm39)	D55E	probably benign	Het

Other mutations in Tspyl5

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02991:Tspyl5	UTSW	15	33,686,989 (GRCm39)	missense	probably damaging	1.00
R0387:Tspyl5	UTSW	15	33,687,081 (GRCm39)	missense	probably damaging	0.99
R1384:Tspyl5	UTSW	15	33,687,526 (GRCm39)	missense	possibly damaging	0.85
R1633:Tspyl5	UTSW	15	33,686,791 (GRCm39)	nonsense	probably null
R1773:Tspyl5	UTSW	15	33,686,922 (GRCm39)	missense	probably benign	0.02
R1928:Tspyl5	UTSW	15	33,687,153 (GRCm39)	missense	probably damaging	1.00
R2083:Tspyl5	UTSW	15	33,686,892 (GRCm39)	missense	probably damaging	1.00
R4524:Tspyl5	UTSW	15	33,687,738 (GRCm39)	missense	probably damaging	0.99
R4909:Tspyl5	UTSW	15	33,686,995 (GRCm39)	missense	probably damaging	0.96
R4994:Tspyl5	UTSW	15	33,687,201 (GRCm39)	missense	possibly damaging	0.81
R8773:Tspyl5	UTSW	15	33,687,238 (GRCm39)	missense	possibly damaging	0.62
R9238:Tspyl5	UTSW	15	33,687,082 (GRCm39)	missense	possibly damaging	0.79
R9690:Tspyl5	UTSW	15	33,687,433 (GRCm39)	missense	probably benign	0.00

Posted On

2014-05-07