Incidental Mutation 'IGL01919:Mrgprx3-ps'
ID180048
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Mrgprx3-ps
Ensembl Gene ENSMUSG00000099560
Gene NameMAS-related GPR, member X3, pseudogene
SynonymsGm660, Gm19419, LOC269919
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.208) question?
Stock #IGL01919
Quality Score
Status
Chromosome7
Chromosomal Location47309378-47310295 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 47310211 bp
ZygosityHeterozygous
Amino Acid Change Threonine to Alanine at position 11 (T11A)
Ref Sequence ENSEMBL: ENSMUSP00000136396 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000179005]
Predicted Effect probably benign
Transcript: ENSMUST00000179005
AA Change: T11A

PolyPhen 2 Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
SMART Domains Protein: ENSMUSP00000136396
Gene: ENSMUSG00000074111
AA Change: T11A

DomainStartEndE-ValueType
Pfam:7tm_1 12 178 3.4e-9 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000187741
Meta Mutation Damage Score 0.1244 question?
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 35 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2700062C07Rik A G 18: 24,475,523 probably null Het
Alms1 T C 6: 85,628,004 F2212S possibly damaging Het
Anpep T C 7: 79,825,350 I155V possibly damaging Het
Aoc1 G A 6: 48,908,289 V653M probably damaging Het
Arl8b T C 6: 108,821,557 probably benign Het
Bax A C 7: 45,466,128 probably null Het
Cpne7 G A 8: 123,125,643 E195K probably damaging Het
Csmd3 A G 15: 47,675,772 I2330T possibly damaging Het
Dnajc16 A G 4: 141,774,629 S297P probably benign Het
Farp2 A G 1: 93,576,433 K311E probably damaging Het
Fhad1 A G 4: 141,964,595 L410P probably damaging Het
Gm10717 C T 9: 3,025,616 S67L probably benign Het
Gm10718 A T 9: 3,025,118 Y194F probably benign Het
Gm12185 T C 11: 48,908,059 T536A possibly damaging Het
Gm21738 G A 14: 19,416,979 S144L probably benign Het
Hydin C T 8: 110,519,174 T2173I possibly damaging Het
Kpnb1 A G 11: 97,164,730 V783A probably benign Het
Krt1 A G 15: 101,846,376 V509A unknown Het
Lrwd1 A T 5: 136,135,875 L26* probably null Het
Mal2 T A 15: 54,588,332 W50R probably damaging Het
Map3k21 A T 8: 125,942,132 E819V probably damaging Het
Mroh2b T C 15: 4,923,688 F635L probably benign Het
Mylip G A 13: 45,408,702 E327K probably damaging Het
Nfix T C 8: 84,726,474 D308G probably damaging Het
Olfr355 G A 2: 36,927,812 Q101* probably null Het
Olfr857 G A 9: 19,713,342 V172I probably benign Het
Psma6 A G 12: 55,407,469 E26G probably damaging Het
Rgs16 T A 1: 153,742,058 S105T probably damaging Het
Slc25a23 T A 17: 57,047,291 N372Y possibly damaging Het
Slc35e2 A G 4: 155,612,730 M234V probably benign Het
Tbc1d8 A G 1: 39,392,253 V346A probably damaging Het
Tgfb1i1 C T 7: 128,248,482 probably benign Het
Triml2 A C 8: 43,190,312 T177P probably damaging Het
Uba6 T C 5: 86,119,386 T959A probably benign Het
Vmn2r-ps159 C T 4: 156,338,254 noncoding transcript Het
Other mutations in Mrgprx3-ps
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01629:Mrgprx3-ps APN 7 47309605 nonsense probably null 0.00
IGL02455:Mrgprx3-ps APN 7 47309515 exon noncoding transcript
R0218:Mrgprx3-ps UTSW 7 47309406 missense possibly damaging 0.87
R0308:Mrgprx3-ps UTSW 7 47310018 missense probably benign 0.25
R4003:Mrgprx3-ps UTSW 7 47310211 missense probably benign 0.00
R4274:Mrgprx3-ps UTSW 7 47309826 exon noncoding transcript
R4411:Mrgprx3-ps UTSW 7 47309998 exon noncoding transcript
R4413:Mrgprx3-ps UTSW 7 47309998 exon noncoding transcript
R5254:Mrgprx3-ps UTSW 7 47309436 exon noncoding transcript
Posted On2014-05-07