Incidental Mutation 'IGL01930:Zscan18'
ID180401
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Zscan18
Ensembl Gene ENSMUSG00000070822
Gene Namezinc finger and SCAN domain containing 18
SynonymsEG232875
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.083) question?
Stock #IGL01930
Quality Score
Status
Chromosome7
Chromosomal Location12768090-12803635 bp(-) (GRCm38)
Type of Mutationunclassified
DNA Base Change (assembly) T to C at 12775348 bp
ZygosityHeterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s): [ENSMUST00000046245] [ENSMUST00000210650] [ENSMUST00000211392]
Predicted Effect unknown
Transcript: ENSMUST00000046245
AA Change: E75G
SMART Domains Protein: ENSMUSP00000047088
Gene: ENSMUSG00000070822
AA Change: E75G

DomainStartEndE-ValueType
low complexity region 10 21 N/A INTRINSIC
low complexity region 30 45 N/A INTRINSIC
low complexity region 72 102 N/A INTRINSIC
low complexity region 118 132 N/A INTRINSIC
low complexity region 134 154 N/A INTRINSIC
internal_repeat_2 159 204 6.76e-5 PROSPERO
internal_repeat_1 197 221 2.66e-6 PROSPERO
low complexity region 225 256 N/A INTRINSIC
low complexity region 262 310 N/A INTRINSIC
low complexity region 312 335 N/A INTRINSIC
internal_repeat_1 353 377 2.66e-6 PROSPERO
SCAN 397 509 1.16e-37 SMART
ZnF_C2H2 776 798 2.24e-3 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000209869
Predicted Effect unknown
Transcript: ENSMUST00000210650
AA Change: E75G
Predicted Effect probably benign
Transcript: ENSMUST00000210891
Predicted Effect unknown
Transcript: ENSMUST00000211392
AA Change: E75G
Predicted Effect noncoding transcript
Transcript: ENSMUST00000211665
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 27 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1810011H11Rik G A 14: 32,816,857 E92K probably benign Het
4930433N12Rik C T 9: 3,134,875 noncoding transcript Het
Acsf3 A G 8: 122,780,346 Y126C probably benign Het
Akr1c20 T A 13: 4,507,648 probably benign Het
Cdan1 T C 2: 120,726,582 probably benign Het
Cdc42bpg C T 19: 6,311,368 A308V probably damaging Het
Dek T C 13: 47,088,135 I318V probably benign Het
Dvl1 A G 4: 155,856,188 M422V possibly damaging Het
Erbin G A 13: 103,841,172 L626F probably damaging Het
Fa2h A T 8: 111,349,304 V229E possibly damaging Het
Gfpt1 T A 6: 87,059,415 H193Q possibly damaging Het
Gm10717 C T 9: 3,025,616 S67L probably benign Het
Gpr162 A G 6: 124,861,612 L25P possibly damaging Het
Hsd3b5 T C 3: 98,622,159 T52A probably benign Het
Megf8 T A 7: 25,334,861 V668D probably damaging Het
Olfr418 T C 1: 173,270,610 V145A probably benign Het
Prkdc A G 16: 15,698,887 T1042A probably damaging Het
Rasgrf2 A G 13: 91,982,738 S735P probably damaging Het
Serpina3n T A 12: 104,408,972 L101H probably damaging Het
Sipa1l2 T C 8: 125,419,239 D1674G probably damaging Het
Sval3 A G 6: 41,972,521 N98D probably benign Het
Tbc1d16 G A 11: 119,156,075 R449C possibly damaging Het
Tm7sf3 A C 6: 146,610,933 I321S possibly damaging Het
Trappc13 A G 13: 104,148,078 probably benign Het
Vmn2r-ps159 C T 4: 156,338,254 noncoding transcript Het
Wdr60 A G 12: 116,225,963 probably null Het
Wdr76 A G 2: 121,510,822 D116G possibly damaging Het
Other mutations in Zscan18
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02152:Zscan18 APN 7 12775296 unclassified probably benign
IGL02236:Zscan18 APN 7 12769324 missense probably benign 0.02
IGL02591:Zscan18 APN 7 12775279 unclassified probably benign
IGL02619:Zscan18 APN 7 12774866 unclassified probably benign
IGL02711:Zscan18 APN 7 12775117 unclassified probably benign
IGL03397:Zscan18 APN 7 12773561 missense probably damaging 0.97
R0014:Zscan18 UTSW 7 12769417 missense possibly damaging 0.48
R0465:Zscan18 UTSW 7 12775486 unclassified probably benign
R0548:Zscan18 UTSW 7 12774176 missense probably damaging 1.00
R1506:Zscan18 UTSW 7 12774202 missense probably damaging 1.00
R1725:Zscan18 UTSW 7 12770857 missense probably damaging 1.00
R2323:Zscan18 UTSW 7 12775459 unclassified probably benign
R5034:Zscan18 UTSW 7 12774145 missense probably damaging 1.00
R5180:Zscan18 UTSW 7 12775289 unclassified probably benign
R5579:Zscan18 UTSW 7 12775381 unclassified probably benign
R5635:Zscan18 UTSW 7 12770864 missense probably benign 0.00
R5708:Zscan18 UTSW 7 12774456 missense probably benign 0.01
R6088:Zscan18 UTSW 7 12775198 unclassified probably benign
R6320:Zscan18 UTSW 7 12775220 unclassified probably benign
R7048:Zscan18 UTSW 7 12774744 unclassified probably benign
Z1088:Zscan18 UTSW 7 12775067 missense probably benign 0.18
Z1088:Zscan18 UTSW 7 12775093 unclassified probably benign
Posted On2014-05-07