Incidental Mutation 'IGL01956:Tas2r102'
| ID |
181101 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Tas2r102
|
| Ensembl Gene |
ENSMUSG00000056901 |
| Gene Name |
taste receptor, type 2, member 102 |
| Synonyms |
STC 9-7, mt2r51, mGR02, Tas2r2 |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
IGL01956
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
6 |
| Chromosomal Location |
132739094-132740137 bp(+) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
G to A
at 132739416 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tryptophan to Stop codon
at position 108
(W108*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000068332
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000069268]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably null
Transcript: ENSMUST00000069268
AA Change: W108*
|
| SMART Domains |
Protein: ENSMUSP00000068332
Gene: ENSMUSG00000056901
AA Change: W108*
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TAS2R
|
21 |
317 |
3.6e-100 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000204939
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 22 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamts3 |
C |
T |
5: 89,825,770 (GRCm39) |
G1022D |
probably damaging |
Het |
| Adgrv1 |
T |
C |
13: 81,594,549 (GRCm39) |
H4155R |
possibly damaging |
Het |
| Akna |
A |
T |
4: 63,297,527 (GRCm39) |
D842E |
probably benign |
Het |
| Cacng5 |
T |
C |
11: 107,773,735 (GRCm39) |
E88G |
possibly damaging |
Het |
| Fbxw18 |
G |
A |
9: 109,522,425 (GRCm39) |
P148L |
probably damaging |
Het |
| Gzf1 |
G |
A |
2: 148,525,981 (GRCm39) |
A151T |
probably benign |
Het |
| Iho1 |
T |
C |
9: 108,294,518 (GRCm39) |
|
probably benign |
Het |
| Myo5c |
A |
G |
9: 75,150,158 (GRCm39) |
|
probably null |
Het |
| Nudcd1 |
A |
G |
15: 44,263,612 (GRCm39) |
Y277H |
probably damaging |
Het |
| Nvl |
A |
G |
1: 180,962,509 (GRCm39) |
S154P |
probably benign |
Het |
| Or6c206 |
T |
A |
10: 129,096,911 (GRCm39) |
I27N |
possibly damaging |
Het |
| Pah |
G |
A |
10: 87,374,061 (GRCm39) |
E76K |
probably benign |
Het |
| Peli1 |
T |
A |
11: 21,098,501 (GRCm39) |
I412N |
probably damaging |
Het |
| Rmc1 |
A |
G |
18: 12,322,407 (GRCm39) |
N620S |
probably damaging |
Het |
| Slc18a2 |
T |
C |
19: 59,275,608 (GRCm39) |
|
probably benign |
Het |
| Stx1a |
T |
C |
5: 135,066,323 (GRCm39) |
|
probably benign |
Het |
| Syne2 |
G |
A |
12: 76,144,748 (GRCm39) |
D1566N |
probably damaging |
Het |
| Syt7 |
G |
T |
19: 10,420,755 (GRCm39) |
E433D |
probably benign |
Het |
| Trappc11 |
A |
G |
8: 47,981,036 (GRCm39) |
V135A |
possibly damaging |
Het |
| Unk |
T |
C |
11: 115,947,160 (GRCm39) |
S598P |
probably damaging |
Het |
| Vmn2r129 |
C |
T |
4: 156,690,549 (GRCm39) |
|
noncoding transcript |
Het |
| Zfp729a |
A |
T |
13: 67,769,805 (GRCm39) |
H141Q |
probably damaging |
Het |
|
| Other mutations in Tas2r102 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00685:Tas2r102
|
APN |
6 |
132,739,488 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
IGL01777:Tas2r102
|
APN |
6 |
132,739,815 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02126:Tas2r102
|
APN |
6 |
132,739,607 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02650:Tas2r102
|
APN |
6 |
132,739,173 (GRCm39) |
missense |
probably null |
0.00 |
|
R0483:Tas2r102
|
UTSW |
6 |
132,739,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0573:Tas2r102
|
UTSW |
6 |
132,739,636 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0726:Tas2r102
|
UTSW |
6 |
132,739,415 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1777:Tas2r102
|
UTSW |
6 |
132,739,254 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3615:Tas2r102
|
UTSW |
6 |
132,739,781 (GRCm39) |
nonsense |
probably null |
|
|
R3616:Tas2r102
|
UTSW |
6 |
132,739,781 (GRCm39) |
nonsense |
probably null |
|
|
R4556:Tas2r102
|
UTSW |
6 |
132,739,878 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4633:Tas2r102
|
UTSW |
6 |
132,739,642 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4724:Tas2r102
|
UTSW |
6 |
132,739,520 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5268:Tas2r102
|
UTSW |
6 |
132,739,360 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5494:Tas2r102
|
UTSW |
6 |
132,740,106 (GRCm39) |
missense |
probably benign |
0.12 |
|
| Posted On |
2014-05-07 |
Incidental Mutation