Incidental Mutation 'IGL01956:Tas2r102'
ID181101
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Tas2r102
Ensembl Gene ENSMUSG00000056901
Gene Nametaste receptor, type 2, member 102
SynonymsTas2r2, mt2r51, mGR02, STC 9-7
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.036) question?
Stock #IGL01956
Quality Score
Status
Chromosome6
Chromosomal Location132762131-132763174 bp(+) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) G to A at 132762453 bp
ZygosityHeterozygous
Amino Acid Change Tryptophan to Stop codon at position 108 (W108*)
Ref Sequence ENSEMBL: ENSMUSP00000068332 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000069268]
Predicted Effect probably null
Transcript: ENSMUST00000069268
AA Change: W108*
SMART Domains Protein: ENSMUSP00000068332
Gene: ENSMUSG00000056901
AA Change: W108*

DomainStartEndE-ValueType
Pfam:TAS2R 21 317 3.6e-100 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000204939
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 22 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
3110002H16Rik A G 18: 12,189,350 N620S probably damaging Het
Adamts3 C T 5: 89,677,911 G1022D probably damaging Het
Adgrv1 T C 13: 81,446,430 H4155R possibly damaging Het
Akna A T 4: 63,379,290 D842E probably benign Het
Cacng5 T C 11: 107,882,909 E88G possibly damaging Het
Ccdc36 T C 9: 108,417,319 probably benign Het
Fbxw18 G A 9: 109,693,357 P148L probably damaging Het
Gzf1 G A 2: 148,684,061 A151T probably benign Het
Myo5c A G 9: 75,242,876 probably null Het
Nudcd1 A G 15: 44,400,216 Y277H probably damaging Het
Nvl A G 1: 181,134,944 S154P probably benign Het
Olfr776 T A 10: 129,261,042 I27N possibly damaging Het
Pah G A 10: 87,538,199 E76K probably benign Het
Peli1 T A 11: 21,148,501 I412N probably damaging Het
Slc18a2 T C 19: 59,287,176 probably benign Het
Stx1a T C 5: 135,037,469 probably benign Het
Syne2 G A 12: 76,097,974 D1566N probably damaging Het
Syt7 G T 19: 10,443,391 E433D probably benign Het
Trappc11 A G 8: 47,528,001 V135A possibly damaging Het
Unk T C 11: 116,056,334 S598P probably damaging Het
Vmn2r-ps159 C T 4: 156,338,254 noncoding transcript Het
Zfp729a A T 13: 67,621,686 H141Q probably damaging Het
Other mutations in Tas2r102
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00685:Tas2r102 APN 6 132762525 missense possibly damaging 0.58
IGL01777:Tas2r102 APN 6 132762852 missense probably damaging 0.98
IGL02126:Tas2r102 APN 6 132762644 missense probably damaging 1.00
IGL02650:Tas2r102 APN 6 132762210 missense probably null 0.00
R0483:Tas2r102 UTSW 6 132762365 missense probably damaging 1.00
R0573:Tas2r102 UTSW 6 132762673 missense probably damaging 0.98
R0726:Tas2r102 UTSW 6 132762452 missense probably damaging 1.00
R1777:Tas2r102 UTSW 6 132762291 missense probably benign 0.08
R3615:Tas2r102 UTSW 6 132762818 nonsense probably null
R3616:Tas2r102 UTSW 6 132762818 nonsense probably null
R4556:Tas2r102 UTSW 6 132762915 missense probably damaging 1.00
R4633:Tas2r102 UTSW 6 132762679 missense possibly damaging 0.87
R4724:Tas2r102 UTSW 6 132762557 missense probably damaging 0.97
R5268:Tas2r102 UTSW 6 132762397 missense probably damaging 0.98
R5494:Tas2r102 UTSW 6 132763143 missense probably benign 0.12
Posted On2014-05-07