Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01953:Vmn1r79'

181318

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r79

Ensembl Gene

ENSMUSG00000096735

Gene Name

vomeronasal 1 receptor 79

Synonyms

Gm9807

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.076) question?

Stock #

IGL01953

Quality Score

Status

Chromosome

Chromosomal Location

11910120-11911040 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 11910382 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Cysteine at position 88 (Y88C)

Ref Sequence

ENSEMBL: ENSMUSP00000154092 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000062811] [ENSMUST00000210112] [ENSMUST00000226953] [ENSMUST00000227530]

AlphaFold

Q8R285

Predicted Effect

probably damaging
Transcript: ENSMUST00000062811
AA Change: Y88C

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000056232
Gene: ENSMUSG00000096735
AA Change: Y88C

Domain	Start	End	E-Value	Type
Pfam:TAS2R	7	302	4.9e-9	PFAM
Pfam:7tm_1	27	292	2.8e-7	PFAM
Pfam:V1R	34	298	1.7e-35	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000210112

Predicted Effect

probably damaging
Transcript: ENSMUST00000226953
AA Change: Y88C

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

Predicted Effect

probably damaging
Transcript: ENSMUST00000227530
AA Change: Y88C

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 42 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Anks3	G	A	16: 4,778,408 (GRCm39)	A8V	probably damaging	Het
Atp6v0a4	A	G	6: 38,031,552 (GRCm39)	S650P	probably damaging	Het
B3glct	C	A	5: 149,669,000 (GRCm39)	D311E	probably benign	Het
Cc2d1a	G	A	8: 84,870,607 (GRCm39)	P119S	probably benign	Het
Cdcp3	T	C	7: 130,826,709 (GRCm39)	M261T	probably benign	Het
Chdh	T	C	14: 29,757,304 (GRCm39)	V409A	probably benign	Het
Cipc	T	A	12: 86,999,538 (GRCm39)	V4E	possibly damaging	Het
Dock2	G	T	11: 34,623,183 (GRCm39)	T70K	probably benign	Het
Dpf1	T	C	7: 29,013,732 (GRCm39)	V269A	probably damaging	Het
Drc7	A	T	8: 95,785,753 (GRCm39)	Y203F	probably damaging	Het
Dsg3	C	T	18: 20,658,361 (GRCm39)	T324I	probably damaging	Het
Gm10718	A	T	9: 3,025,118 (GRCm39)	Y194F	probably benign	Het
Iqcd	A	T	5: 120,738,554 (GRCm39)	N124I	probably benign	Het
Kdm7a	T	C	6: 39,123,836 (GRCm39)	N776S	probably benign	Het
Lama5	C	T	2: 179,832,497 (GRCm39)	R1684H	probably damaging	Het
Lrp12	A	T	15: 39,741,497 (GRCm39)	V406D	probably damaging	Het
Lrrc74a	T	A	12: 86,788,494 (GRCm39)	L158Q	probably damaging	Het
Mef2d	C	T	3: 88,063,813 (GRCm39)	T80I	probably damaging	Het
Megf11	T	C	9: 64,597,370 (GRCm39)	C681R	probably damaging	Het
Mex3c	A	G	18: 73,723,104 (GRCm39)	D399G	probably damaging	Het
Muc20	T	C	16: 32,614,073 (GRCm39)	T435A	probably benign	Het
Myo5b	T	C	18: 74,702,838 (GRCm39)	Y10H	possibly damaging	Het
Or12d13	T	C	17: 37,647,766 (GRCm39)	D119G	probably damaging	Het
Or4k40	A	G	2: 111,250,657 (GRCm39)	L213P	probably benign	Het
Otoa	T	A	7: 120,759,548 (GRCm39)		probably null	Het
P4ha2	T	C	11: 54,004,996 (GRCm39)	F124S	probably benign	Het
Phkg2	C	T	7: 127,181,512 (GRCm39)	P232S	probably damaging	Het
Piezo1	T	A	8: 123,217,923 (GRCm39)	Q800L	probably damaging	Het
Pign	C	A	1: 105,516,764 (GRCm39)		probably benign	Het
Pik3r5	A	G	11: 68,384,997 (GRCm39)	D634G	probably benign	Het
Ptpn9	A	G	9: 56,964,072 (GRCm39)	T402A	possibly damaging	Het
Relb	A	C	7: 19,349,482 (GRCm39)		probably null	Het
Scgb1b30	A	G	7: 33,799,302 (GRCm39)	Q78R	probably damaging	Het
Sema6a	C	T	18: 47,423,187 (GRCm39)	W273*	probably null	Het
Sestd1	A	G	2: 77,042,813 (GRCm39)	V247A	possibly damaging	Het
Specc1	T	A	11: 62,009,122 (GRCm39)	S293T	probably benign	Het
Sptbn2	A	G	19: 4,799,721 (GRCm39)	D2145G	probably benign	Het
Trim43b	T	A	9: 88,967,496 (GRCm39)	D380V	possibly damaging	Het
Vmn1r236	A	G	17: 21,507,473 (GRCm39)	Y197C	possibly damaging	Het
Vmn2r129	C	T	4: 156,690,549 (GRCm39)		noncoding transcript	Het
Vmn2r61	G	A	7: 41,949,613 (GRCm39)	V678M	probably damaging	Het
Wdfy3	A	T	5: 102,042,894 (GRCm39)	Y1937*	probably null	Het

Other mutations in Vmn1r79

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00592:Vmn1r79	APN	7	11,910,934 (GRCm39)	missense	probably benign	0.05
IGL01431:Vmn1r79	APN	7	11,910,327 (GRCm39)	missense	possibly damaging	0.88
PIT4418001:Vmn1r79	UTSW	7	11,910,766 (GRCm39)	missense	probably damaging	1.00
R0831:Vmn1r79	UTSW	7	11,910,990 (GRCm39)	missense	probably damaging	0.98
R1791:Vmn1r79	UTSW	7	11,910,358 (GRCm39)	missense	probably damaging	1.00
R1869:Vmn1r79	UTSW	7	11,910,574 (GRCm39)	missense	probably benign	0.00
R3713:Vmn1r79	UTSW	7	11,910,139 (GRCm39)	missense	possibly damaging	0.66
R4210:Vmn1r79	UTSW	7	11,910,415 (GRCm39)	missense	possibly damaging	0.46
R4243:Vmn1r79	UTSW	7	11,910,971 (GRCm39)	nonsense	probably null
R4244:Vmn1r79	UTSW	7	11,910,971 (GRCm39)	nonsense	probably null
R4839:Vmn1r79	UTSW	7	11,910,361 (GRCm39)	missense	probably benign	0.30
R5677:Vmn1r79	UTSW	7	11,910,928 (GRCm39)	missense	possibly damaging	0.77
R6048:Vmn1r79	UTSW	7	11,910,448 (GRCm39)	missense	probably damaging	0.99
R7388:Vmn1r79	UTSW	7	11,910,668 (GRCm39)	nonsense	probably null
R7751:Vmn1r79	UTSW	7	11,910,762 (GRCm39)	nonsense	probably null
R8207:Vmn1r79	UTSW	7	11,910,415 (GRCm39)	missense	possibly damaging	0.46
R9462:Vmn1r79	UTSW	7	11,910,261 (GRCm39)	missense	probably damaging	1.00
R9664:Vmn1r79	UTSW	7	11,910,582 (GRCm39)	missense	probably benign	0.00
R9749:Vmn1r79	UTSW	7	11,910,450 (GRCm39)	missense	probably damaging	1.00

Posted On

2014-05-07