Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01964:Vmn1r198'

181500

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r198

Ensembl Gene

ENSMUSG00000095125

Gene Name

vomeronasal 1 receptor 198

Synonyms

V1ri3

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.079) question?

Stock #

IGL01964

Quality Score

Status

Chromosome

Chromosomal Location

22538516-22539418 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 22538576 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Methionine to Valine at position 21 (M21V)

Ref Sequence

ENSEMBL: ENSMUSP00000153942 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000091733] [ENSMUST00000226786] [ENSMUST00000226909] [ENSMUST00000227167]

AlphaFold

Q8R263

Predicted Effect

probably benign
Transcript: ENSMUST00000091733
AA Change: M21V

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000089327
Gene: ENSMUSG00000095125
AA Change: M21V

Domain	Start	End	E-Value	Type
Pfam:TAS2R	1	299	9.3e-7	PFAM
Pfam:V1R	35	299	5.5e-39	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000226786
AA Change: M21V

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

Predicted Effect

probably benign
Transcript: ENSMUST00000226909
AA Change: M21V

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

Predicted Effect

probably benign
Transcript: ENSMUST00000227167

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 27 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adam34l	A	C	8: 44,079,798 (GRCm39)	I142S	probably benign	Het
Aknad1	T	C	3: 108,685,593 (GRCm39)	V579A	probably benign	Het
Ankrd11	A	G	8: 123,616,475 (GRCm39)	I2438T	probably damaging	Het
Cdh11	A	G	8: 103,391,375 (GRCm39)	V287A	probably benign	Het
Cdyl2	G	A	8: 117,350,768 (GRCm39)	S121L	probably benign	Het
Cyp2e1	A	T	7: 140,343,779 (GRCm39)	I6F	probably damaging	Het
Cyp3a16	A	T	5: 145,392,372 (GRCm39)	D194E	probably benign	Het
Eapp	G	T	12: 54,732,720 (GRCm39)	P126Q	probably damaging	Het
Efr3b	A	T	12: 4,032,928 (GRCm39)	L143Q	probably damaging	Het
Grin2c	C	T	11: 115,144,673 (GRCm39)	E618K	probably damaging	Het
Haus3	A	T	5: 34,323,405 (GRCm39)	Y402N	probably benign	Het
Iffo1	A	G	6: 125,128,364 (GRCm39)	D316G	probably damaging	Het
Kctd19	A	T	8: 106,115,157 (GRCm39)	M468K	probably damaging	Het
Kdm4b	T	A	17: 56,696,256 (GRCm39)		probably null	Het
Naip6	T	A	13: 100,435,238 (GRCm39)		probably benign	Het
Or5k15	A	T	16: 58,709,827 (GRCm39)	I252K	probably damaging	Het
Polr3c	T	C	3: 96,619,291 (GRCm39)		probably benign	Het
Poteg	A	T	8: 27,938,036 (GRCm39)	E60V	probably damaging	Het
Rnd2	T	C	11: 101,361,632 (GRCm39)		probably null	Het
Rufy3	A	G	5: 88,762,929 (GRCm39)	Q153R	probably damaging	Het
Shank1	T	A	7: 43,975,102 (GRCm39)	I399N	unknown	Het
Sin3a	T	C	9: 57,014,631 (GRCm39)		probably benign	Het
Sppl2b	T	A	10: 80,701,220 (GRCm39)		probably null	Het
Srgap1	G	A	10: 121,640,871 (GRCm39)	P665L	possibly damaging	Het
Srgap2	G	T	1: 131,217,316 (GRCm39)	Q999K	probably benign	Het
Tbxas1	G	A	6: 39,060,748 (GRCm39)	V496I	probably benign	Het
Wdr90	T	C	17: 26,067,383 (GRCm39)	I1479V	probably benign	Het

Other mutations in Vmn1r198

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL03381:Vmn1r198	APN	13	22,539,006 (GRCm39)	missense	probably benign	0.07
R0498:Vmn1r198	UTSW	13	22,539,144 (GRCm39)	missense	probably damaging	1.00
R0755:Vmn1r198	UTSW	13	22,539,402 (GRCm39)	missense	probably benign	0.00
R2092:Vmn1r198	UTSW	13	22,538,885 (GRCm39)	missense	possibly damaging	0.95
R2093:Vmn1r198	UTSW	13	22,538,855 (GRCm39)	missense	probably benign	0.25
R5571:Vmn1r198	UTSW	13	22,539,168 (GRCm39)	missense	probably damaging	0.99
R5943:Vmn1r198	UTSW	13	22,539,367 (GRCm39)	nonsense	probably null
R6083:Vmn1r198	UTSW	13	22,538,928 (GRCm39)	missense	possibly damaging	0.80
R6531:Vmn1r198	UTSW	13	22,538,577 (GRCm39)	missense	probably benign	0.01
R8765:Vmn1r198	UTSW	13	22,539,269 (GRCm39)	missense	probably damaging	0.97
R8935:Vmn1r198	UTSW	13	22,539,092 (GRCm39)	nonsense	probably null
R9514:Vmn1r198	UTSW	13	22,539,015 (GRCm39)	missense	possibly damaging	0.58
X0024:Vmn1r198	UTSW	13	22,538,680 (GRCm39)	missense	probably benign

Posted On

2014-05-07