Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01984:Sult3a1'

181822

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Sult3a1

Ensembl Gene

ENSMUSG00000069668

Gene Name

sulfotransferase family 3A, member 1

Synonyms

Sultx2

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.194) question?

Stock #

IGL01984

Quality Score

Status

Chromosome

Chromosomal Location

33733717-33755528 bp(+) (GRCm39)

Type of Mutation

nonsense

DNA Base Change (assembly)

G to T at 33755205 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Glycine to Stop codon at position 257 (G257*)

Ref Sequence

ENSEMBL: ENSMUSP00000151228 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000092597] [ENSMUST00000218204]

AlphaFold

no structure available at present

Predicted Effect

probably null
Transcript: ENSMUST00000092597
AA Change: G257*

SMART Domains

Protein: ENSMUSP00000090259
Gene: ENSMUSG00000069668
AA Change: G257*

Domain	Start	End	E-Value	Type
Pfam:Sulfotransfer_1	36	283	1.8e-81	PFAM

Predicted Effect

probably null
Transcript: ENSMUST00000218204
AA Change: G257*

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 33 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4933434E20Rik	C	T	3: 89,970,537 (GRCm39)	L24F	probably benign	Het
Adamts16	T	C	13: 70,935,266 (GRCm39)	D442G	probably damaging	Het
Ankmy1	T	C	1: 92,811,487 (GRCm39)	T634A	probably damaging	Het
Anxa3	A	T	5: 96,982,630 (GRCm39)		probably benign	Het
Ccnh	T	C	13: 85,354,270 (GRCm39)	L202P	probably damaging	Het
Clcn3	A	T	8: 61,382,614 (GRCm39)	S325T	probably damaging	Het
Clec2d	A	T	6: 129,161,192 (GRCm39)	E96D	possibly damaging	Het
Csn1s1	A	T	5: 87,824,369 (GRCm39)		probably benign	Het
Dcun1d5	T	A	9: 7,205,307 (GRCm39)	Y189N	possibly damaging	Het
Dnah7a	T	C	1: 53,741,174 (GRCm39)		probably null	Het
Dpcd	C	T	19: 45,565,469 (GRCm39)	H148Y	probably benign	Het
Efcab3	T	A	11: 104,629,134 (GRCm39)	D937E	probably benign	Het
Erg	T	G	16: 95,210,786 (GRCm39)	D15A	probably damaging	Het
Gm21759	T	A	5: 8,230,547 (GRCm39)		probably benign	Het
Heatr5b	C	T	17: 79,103,926 (GRCm39)	R1083Q	possibly damaging	Het
Ints3	A	G	3: 90,299,533 (GRCm39)	S1012P	possibly damaging	Het
Klhl3	C	T	13: 58,159,057 (GRCm39)		probably benign	Het
Lama4	T	A	10: 38,951,525 (GRCm39)		probably null	Het
Magi1	A	T	6: 93,685,155 (GRCm39)	V740D	probably damaging	Het
Nme8	C	A	13: 19,873,150 (GRCm39)	V165L	probably damaging	Het
Odf2l	G	T	3: 144,845,590 (GRCm39)	E5*	probably null	Het
Or14j4	T	C	17: 37,934,552 (GRCm39)		probably benign	Het
Or4k47	A	G	2: 111,451,927 (GRCm39)	L164S	probably benign	Het
Or56a5	A	T	7: 104,792,923 (GRCm39)	D192E	probably benign	Het
Pcnx4	T	C	12: 72,621,183 (GRCm39)	V1001A	probably benign	Het
Plaa	A	G	4: 94,459,922 (GRCm39)		probably null	Het
Prkdc	G	A	16: 15,526,643 (GRCm39)	A1305T	probably benign	Het
Rnps1	T	C	17: 24,643,371 (GRCm39)		probably benign	Het
St8sia5	T	C	18: 77,336,157 (GRCm39)	F197L	probably benign	Het
Svep1	A	C	4: 58,068,877 (GRCm39)	Y2970D	possibly damaging	Het
Tns3	G	T	11: 8,498,992 (GRCm39)	Y30*	probably null	Het
Ubr1	G	T	2: 120,751,867 (GRCm39)	P791T	probably damaging	Het
Zfp592	T	C	7: 80,688,392 (GRCm39)	V1039A	probably benign	Het

Other mutations in Sult3a1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02269:Sult3a1	APN	10	33,755,259 (GRCm39)	missense	probably benign	0.25
IGL02302:Sult3a1	APN	10	33,742,571 (GRCm39)	missense	possibly damaging	0.81
IGL02947:Sult3a1	APN	10	33,740,046 (GRCm39)	missense	possibly damaging	0.92
IGL02966:Sult3a1	APN	10	33,753,269 (GRCm39)	splice site	probably benign
IGL03271:Sult3a1	APN	10	33,739,997 (GRCm39)	missense	probably benign
IGL03367:Sult3a1	APN	10	33,753,342 (GRCm39)	missense	probably benign	0.01
R0539:Sult3a1	UTSW	10	33,742,519 (GRCm39)	missense	probably damaging	1.00
R0627:Sult3a1	UTSW	10	33,740,010 (GRCm39)	missense	probably benign	0.00
R0838:Sult3a1	UTSW	10	33,755,284 (GRCm39)	missense	probably damaging	0.99
R1538:Sult3a1	UTSW	10	33,746,166 (GRCm39)	missense	probably benign	0.29
R1604:Sult3a1	UTSW	10	33,742,616 (GRCm39)	missense	probably damaging	1.00
R1622:Sult3a1	UTSW	10	33,746,246 (GRCm39)	missense	probably benign	0.39
R3031:Sult3a1	UTSW	10	33,753,345 (GRCm39)	missense	possibly damaging	0.70
R4933:Sult3a1	UTSW	10	33,742,550 (GRCm39)	missense	probably damaging	1.00
R5943:Sult3a1	UTSW	10	33,742,637 (GRCm39)	missense	probably damaging	0.99
R6440:Sult3a1	UTSW	10	33,746,198 (GRCm39)	missense	possibly damaging	0.46
R7140:Sult3a1	UTSW	10	33,753,283 (GRCm39)	missense	probably damaging	1.00
R7356:Sult3a1	UTSW	10	33,742,579 (GRCm39)	missense	probably benign	0.25
R8342:Sult3a1	UTSW	10	33,742,517 (GRCm39)	missense	probably damaging	1.00

Posted On

2014-05-07