Incidental Mutation 'IGL02007:Igkv3-9'
ID182259
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Igkv3-9
Ensembl Gene ENSMUSG00000095338
Gene Nameimmunoglobulin kappa variable 3-9
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.136) question?
Stock #IGL02007
Quality Score
Status
Chromosome6
Chromosomal Location70588189-70588777 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to G at 70588461 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000100199 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000103398]
Predicted Effect probably benign
Transcript: ENSMUST00000103398
SMART Domains Protein: ENSMUSP00000100199
Gene: ENSMUSG00000095338

DomainStartEndE-ValueType
signal peptide 1 20 N/A INTRINSIC
IGv 38 114 8.17e-18 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000197635
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 28 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adam28 C A 14: 68,633,219 R335L possibly damaging Het
Adgrv1 T C 13: 81,568,743 probably benign Het
Calcrl A G 2: 84,375,324 C8R probably benign Het
Cntn4 T A 6: 106,655,529 S505T probably benign Het
Cyp3a16 T C 5: 145,441,948 probably benign Het
Fam160a1 G T 3: 85,722,445 P280T probably damaging Het
Gm11127 G T 17: 36,056,330 N333K possibly damaging Het
Gpatch11 A G 17: 78,842,164 T198A probably benign Het
Heatr5a C A 12: 51,916,158 L986F probably damaging Het
Ift172 A G 5: 31,286,604 I90T probably benign Het
Iqsec1 G A 6: 90,690,349 P369S probably benign Het
Myh1 C A 11: 67,220,556 T1607K probably benign Het
Myo18b T C 5: 112,874,972 probably benign Het
Nobox A G 6: 43,307,538 L58P probably damaging Het
Nwd2 T A 5: 63,804,699 I542N possibly damaging Het
Olfr1301 A G 2: 111,754,479 T77A probably damaging Het
Olfr474 A G 7: 107,954,746 Y35C probably damaging Het
Osm C T 11: 4,239,470 R85W probably damaging Het
Pcdh20 T C 14: 88,469,595 R90G probably benign Het
Pkhd1l1 T C 15: 44,533,733 probably benign Het
Sec14l2 A G 11: 4,111,114 S116P probably benign Het
Selenbp2 A C 3: 94,698,154 N96H possibly damaging Het
Smarcal1 T C 1: 72,595,940 S393P probably damaging Het
Tbc1d1 A G 5: 64,256,992 Q103R probably damaging Het
Tmem63c T C 12: 87,072,873 Y314H probably damaging Het
Wdr34 A G 2: 30,038,390 S75P probably benign Het
Zfp663 A C 2: 165,359,073 S14A probably benign Het
Zmynd10 A G 9: 107,550,532 N345S probably damaging Het
Other mutations in Igkv3-9
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02589:Igkv3-9 APN 6 70588699 missense possibly damaging 0.90
R2509:Igkv3-9 UTSW 6 70588744 missense probably benign 0.03
R4411:Igkv3-9 UTSW 6 70588563 missense probably damaging 0.97
R5498:Igkv3-9 UTSW 6 70588743 missense probably benign
R7302:Igkv3-9 UTSW 6 70588755 missense probably benign 0.01
R7487:Igkv3-9 UTSW 6 70588522 missense probably damaging 0.99
Posted On2014-05-07