Incidental Mutation 'IGL01963:Krtap26-1'
ID182472
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Krtap26-1
Ensembl Gene ENSMUSG00000071471
Gene Namekeratin associated protein 26-1
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.033) question?
Stock #IGL01963
Quality Score
Status
Chromosome16
Chromosomal Location88646824-88647796 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 88647668 bp
ZygosityHeterozygous
Amino Acid Change Cysteine to Arginine at position 22 (C22R)
Ref Sequence ENSEMBL: ENSMUSP00000093626 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000095934]
Predicted Effect probably damaging
Transcript: ENSMUST00000095934
AA Change: C22R

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000093626
Gene: ENSMUSG00000071471
AA Change: C22R

DomainStartEndE-ValueType
Pfam:PMG 4 213 2.9e-65 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 31 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2610042L04Rik G A 14: 4,350,856 G130D probably damaging Het
Abca8b T A 11: 109,971,763 D392V probably damaging Het
Clptm1l T A 13: 73,617,569 probably benign Het
Creb3l1 G A 2: 91,993,333 T178I probably benign Het
Ctsd A G 7: 142,376,599 probably null Het
Dcstamp A T 15: 39,760,359 I401F possibly damaging Het
Dnah5 A G 15: 28,370,536 D2874G probably benign Het
Fgfr1op A T 17: 8,192,277 D354V probably damaging Het
Fli1 T A 9: 32,424,207 K310* probably null Het
Fndc4 C T 5: 31,295,212 probably null Het
Fuk A G 8: 110,893,402 F281S probably damaging Het
Gc G A 5: 89,422,122 probably benign Het
Obscn C T 11: 59,020,541 G6422S probably benign Het
Olfr1444 T A 19: 12,862,382 F202L probably benign Het
Olfr418 T A 1: 173,270,352 M59K probably damaging Het
Olfr975 C A 9: 39,950,240 C177F probably damaging Het
Pgr C T 9: 8,922,668 P613L probably damaging Het
Pnpla8 C A 12: 44,296,033 A524E possibly damaging Het
Psma2 A T 13: 14,619,363 I105F probably damaging Het
Ptprg A G 14: 12,220,661 R458G probably damaging Het
Rbm44 A G 1: 91,163,108 I755V probably benign Het
Rev3l A G 10: 39,822,737 K1077E possibly damaging Het
Rps20 A C 4: 3,834,494 probably benign Het
Sel1l3 A C 5: 53,200,338 V104G probably damaging Het
Sirpb1c T C 3: 15,838,773 N89S probably benign Het
Slc25a16 G A 10: 62,930,441 probably null Het
Sulf1 C T 1: 12,818,507 R339C probably damaging Het
Tedc2 C T 17: 24,217,952 A270T probably benign Het
Trem3 T C 17: 48,247,852 S2P possibly damaging Het
Vps37a G T 8: 40,540,730 Q255H probably damaging Het
Zfp352 C T 4: 90,224,154 A177V possibly damaging Het
Other mutations in Krtap26-1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00886:Krtap26-1 APN 16 88647379 missense possibly damaging 0.62
IGL01721:Krtap26-1 APN 16 88647172 missense probably damaging 1.00
IGL02524:Krtap26-1 APN 16 88647479 missense possibly damaging 0.70
R0383:Krtap26-1 UTSW 16 88647243 nonsense probably null
R2367:Krtap26-1 UTSW 16 88647325 missense probably benign 0.28
R4694:Krtap26-1 UTSW 16 88647220 missense possibly damaging 0.70
R6699:Krtap26-1 UTSW 16 88647715 missense unknown
R6884:Krtap26-1 UTSW 16 88647579 missense probably damaging 1.00
Posted On2014-05-07