Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01998:Tex55'

182953

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tex55

Ensembl Gene

ENSMUSG00000022798

Gene Name

testis expressed 55

Synonyms

4930435E12Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.070) question?

Stock #

IGL01998

Quality Score

Status

Chromosome

Chromosomal Location

38632568-38649111 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 38648586 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glutamic Acid at position 174 (D174E)

Ref Sequence

ENSEMBL: ENSMUSP00000113120 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000122078]

AlphaFold

A6X8Z9

Predicted Effect

probably benign
Transcript: ENSMUST00000122078
AA Change: D174E

PolyPhen 2 Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)

SMART Domains

Protein: ENSMUSP00000113120
Gene: ENSMUSG00000022798
AA Change: D174E

Domain	Start	End	E-Value	Type
low complexity region	86	97	N/A	INTRINSIC
low complexity region	244	254	N/A	INTRINSIC
low complexity region	307	317	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000130241

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000148657

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000209595

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 52 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Arpc3	T	C	5: 122,541,470 (GRCm39)	C78R	probably damaging	Het
Atp6v0b	A	G	4: 117,743,263 (GRCm39)		probably null	Het
B3gnt8	A	G	7: 25,328,203 (GRCm39)	Y211C	probably damaging	Het
Birc6	T	C	17: 74,886,880 (GRCm39)	I736T	probably benign	Het
Bltp1	T	C	3: 37,011,165 (GRCm39)	S1788P	possibly damaging	Het
Bpifb9a	T	C	2: 154,110,120 (GRCm39)		probably null	Het
C3ar1	A	T	6: 122,827,899 (GRCm39)	M106K	probably damaging	Het
C9orf72	A	T	4: 35,194,179 (GRCm39)	D205E	probably benign	Het
Cab39l	T	A	14: 59,734,344 (GRCm39)	L21Q	probably damaging	Het
Casp1	A	T	9: 5,303,043 (GRCm39)	I166F	probably damaging	Het
Cd180	A	G	13: 102,841,722 (GRCm39)	E256G	probably damaging	Het
Clca4a	T	C	3: 144,663,887 (GRCm39)	T519A	probably damaging	Het
Clstn3	A	T	6: 124,435,622 (GRCm39)	L233Q	probably damaging	Het
Crlf3	G	A	11: 79,948,845 (GRCm39)		probably benign	Het
Depdc5	T	C	5: 33,102,495 (GRCm39)		probably benign	Het
Drc7	T	A	8: 95,785,821 (GRCm39)	C226S	probably damaging	Het
Epha5	T	A	5: 84,232,593 (GRCm39)	D807V	probably damaging	Het
Fat2	A	G	11: 55,187,021 (GRCm39)	L1275P	probably benign	Het
Fv1	T	C	4: 147,953,784 (GRCm39)	C117R	possibly damaging	Het
Ighg2b	C	A	12: 113,270,709 (GRCm39)	M140I	unknown	Het
Klra5	A	T	6: 129,883,676 (GRCm39)	Y60*	probably null	Het
Lmtk2	C	T	5: 144,112,883 (GRCm39)	T1201I	probably damaging	Het
Ncapd2	A	T	6: 125,150,078 (GRCm39)	S917T	probably benign	Het
Ncapd2	A	T	6: 125,146,896 (GRCm39)	L1230H	probably damaging	Het
Nfx1	T	A	4: 41,004,353 (GRCm39)	I708N	probably damaging	Het
Notch2	A	T	3: 98,050,422 (GRCm39)	D1899V	probably damaging	Het
Npepl1	T	A	2: 173,957,993 (GRCm39)		probably benign	Het
Nps	T	A	7: 134,870,481 (GRCm39)		probably benign	Het
Nrg1	T	C	8: 32,408,162 (GRCm39)	S24G	probably damaging	Het
Or1j20	A	G	2: 36,759,658 (GRCm39)	N27D	probably benign	Het
Or2ag16	G	A	7: 106,351,758 (GRCm39)	T279M	possibly damaging	Het
Or2t48	A	T	11: 58,420,403 (GRCm39)	Y136*	probably null	Het
Or4k2	C	A	14: 50,424,105 (GRCm39)	V190L	probably benign	Het
Pigx	G	T	16: 31,903,428 (GRCm39)	T211K	probably benign	Het
Pink1	A	G	4: 138,048,053 (GRCm39)	I223T	probably damaging	Het
Plat	G	A	8: 23,257,163 (GRCm39)	A15T	probably benign	Het
Ptges2	G	A	2: 32,291,542 (GRCm39)	A310T	possibly damaging	Het
Rsl1d1	A	G	16: 11,012,509 (GRCm39)	S306P	possibly damaging	Het
Rxfp1	T	C	3: 79,567,403 (GRCm39)	K316E	probably benign	Het
Scn10a	A	G	9: 119,438,742 (GRCm39)	I1708T	probably damaging	Het
Sdk2	A	T	11: 113,729,358 (GRCm39)	F1073Y	probably damaging	Het
Sp100	A	G	1: 85,594,650 (GRCm39)	D170G	probably benign	Het
Spock1	A	T	13: 57,583,994 (GRCm39)		probably benign	Het
Strbp	A	G	2: 37,515,297 (GRCm39)	L243P	probably damaging	Het
Tgm5	T	A	2: 120,882,920 (GRCm39)	T446S	probably damaging	Het
Tmem59l	C	T	8: 70,937,431 (GRCm39)	V239I	probably benign	Het
Trav8-1	A	T	14: 53,707,662 (GRCm39)	T101S	probably benign	Het
Triml1	T	C	8: 43,594,350 (GRCm39)	D27G	probably damaging	Het
Vmn2r54	T	C	7: 12,349,227 (GRCm39)	E785G	probably benign	Het
Vps13c	A	G	9: 67,862,350 (GRCm39)		probably null	Het
Wwp2	C	T	8: 108,276,153 (GRCm39)	R64C	probably damaging	Het
Zfp608	T	C	18: 55,024,890 (GRCm39)	H1460R	probably damaging	Het

Other mutations in Tex55

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01979:Tex55	APN	16	38,648,255 (GRCm39)	missense	possibly damaging	0.61
IGL02454:Tex55	APN	16	38,648,309 (GRCm39)	missense	probably benign	0.02
IGL03216:Tex55	APN	16	38,649,052 (GRCm39)	missense	possibly damaging	0.59
IGL03325:Tex55	APN	16	38,648,355 (GRCm39)	missense	probably damaging	1.00
IGL03397:Tex55	APN	16	38,649,055 (GRCm39)	missense	probably damaging	1.00
R7924_4930435E12Rik_239	UTSW	16	38,632,826 (GRCm39)	nonsense	probably null
BB001:Tex55	UTSW	16	38,632,826 (GRCm39)	nonsense	probably null
BB011:Tex55	UTSW	16	38,632,826 (GRCm39)	nonsense	probably null
R0242:Tex55	UTSW	16	38,644,929 (GRCm39)	splice site	probably benign
R0446:Tex55	UTSW	16	38,649,064 (GRCm39)	missense	probably benign	0.01
R0607:Tex55	UTSW	16	38,648,726 (GRCm39)	missense	probably benign	0.02
R1918:Tex55	UTSW	16	38,648,450 (GRCm39)	missense	possibly damaging	0.56
R1953:Tex55	UTSW	16	38,648,275 (GRCm39)	missense	possibly damaging	0.78
R3417:Tex55	UTSW	16	38,649,102 (GRCm39)	missense	probably benign	0.17
R4601:Tex55	UTSW	16	38,648,380 (GRCm39)	missense	probably benign	0.14
R4860:Tex55	UTSW	16	38,648,507 (GRCm39)	missense	probably damaging	0.97
R4860:Tex55	UTSW	16	38,648,507 (GRCm39)	missense	probably damaging	0.97
R5551:Tex55	UTSW	16	38,648,336 (GRCm39)	missense	probably benign	0.28
R7568:Tex55	UTSW	16	38,648,809 (GRCm39)	missense	possibly damaging	0.95
R7623:Tex55	UTSW	16	38,648,453 (GRCm39)	missense	possibly damaging	0.87
R7643:Tex55	UTSW	16	38,648,225 (GRCm39)	missense	probably benign	0.15
R7669:Tex55	UTSW	16	38,648,453 (GRCm39)	missense	possibly damaging	0.87
R7670:Tex55	UTSW	16	38,648,453 (GRCm39)	missense	possibly damaging	0.87
R7671:Tex55	UTSW	16	38,648,453 (GRCm39)	missense	possibly damaging	0.87
R7924:Tex55	UTSW	16	38,632,826 (GRCm39)	nonsense	probably null
R9385:Tex55	UTSW	16	38,648,407 (GRCm39)	missense	probably benign	0.11
RF013:Tex55	UTSW	16	38,648,363 (GRCm39)	missense	probably benign	0.37

Posted On

2014-05-07