Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01992:Tex56'

183586

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tex56

Ensembl Gene

ENSMUSG00000021415

Gene Name

testis expressed 56

Synonyms

4933417A18Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.062) question?

Stock #

IGL01992

Quality Score

Status

Chromosome

Chromosomal Location

35108392-35139858 bp(+) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

C to T at 35108516 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000153297 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000021851] [ENSMUST00000160279] [ENSMUST00000160905] [ENSMUST00000223834]

AlphaFold

no structure available at present

Predicted Effect

probably null
Transcript: ENSMUST00000021851

SMART Domains

Protein: ENSMUSP00000021851
Gene: ENSMUSG00000021414

Domain	Start	End	E-Value	Type
low complexity region	5	19	N/A	INTRINSIC
Pfam:FAM217	206	411	2e-54	PFAM
low complexity region	425	436	N/A	INTRINSIC
low complexity region	444	455	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000160279

SMART Domains

Protein: ENSMUSP00000125324
Gene: ENSMUSG00000021415

Domain	Start	End	E-Value	Type
Pfam:DUF4523	34	199	1.1e-89	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000160905

SMART Domains

Protein: ENSMUSP00000125206
Gene: ENSMUSG00000021415

Domain	Start	End	E-Value	Type
Pfam:DUF4523	34	199	9.5e-102	PFAM

Predicted Effect

probably null
Transcript: ENSMUST00000223834

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 41 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Ano3	A	G	2: 110,488,564 (GRCm39)	M956T	probably damaging	Het
Ap2b1	T	G	11: 83,226,356 (GRCm39)	V289G	probably damaging	Het
Cacnb4	G	T	2: 52,355,682 (GRCm39)	H208Q	probably damaging	Het
Calhm6	A	T	10: 34,003,533 (GRCm39)	C125S	probably damaging	Het
Cd5l	G	A	3: 87,275,118 (GRCm39)	R219Q	probably benign	Het
Dzip1l	G	T	9: 99,545,739 (GRCm39)	G663W	probably damaging	Het
Ecel1	G	A	1: 87,077,577 (GRCm39)		probably benign	Het
Eno1	A	G	4: 150,323,993 (GRCm39)	T19A	probably damaging	Het
Fndc3a	G	A	14: 72,811,996 (GRCm39)	T315I	probably benign	Het
Galr1	T	C	18: 82,411,942 (GRCm39)	N308S	probably damaging	Het
Get3	G	A	8: 85,745,185 (GRCm39)	A294V	possibly damaging	Het
Maf	A	T	8: 116,432,702 (GRCm39)	S301T	probably damaging	Het
Map3k5	C	T	10: 19,904,879 (GRCm39)	R394*	probably null	Het
Mroh8	C	T	2: 157,055,616 (GRCm39)	G994D	probably damaging	Het
Myo10	T	C	15: 25,799,634 (GRCm39)	V653A	possibly damaging	Het
Nucks1	A	G	1: 131,858,828 (GRCm39)	K196E	unknown	Het
Nup42	T	C	5: 24,386,101 (GRCm39)	V211A	probably benign	Het
Or4n4	C	A	14: 50,518,798 (GRCm39)	R304L	probably benign	Het
Or7e178	A	T	9: 20,226,015 (GRCm39)	I59N	probably damaging	Het
Or7g32	A	T	9: 19,408,070 (GRCm39)	I9F	probably benign	Het
Piwil1	C	T	5: 128,824,396 (GRCm39)	T493I	probably null	Het
Plcd1	T	C	9: 118,905,053 (GRCm39)	H216R	probably benign	Het
Pmp2	A	T	3: 10,247,541 (GRCm39)	Y49*	probably null	Het
Rnf38	A	G	4: 44,138,806 (GRCm39)	V229A	probably damaging	Het
Saxo2	T	C	7: 82,284,108 (GRCm39)	D250G	probably damaging	Het
Scn8a	T	G	15: 100,866,938 (GRCm39)	V98G	probably damaging	Het
Scnn1a	T	A	6: 125,315,900 (GRCm39)		probably null	Het
Sepsecs	C	T	5: 52,801,402 (GRCm39)	R420Q	probably benign	Het
Slit2	T	C	5: 48,395,759 (GRCm39)	S725P	probably benign	Het
Stk16	A	G	1: 75,189,835 (GRCm39)	Q207R	probably benign	Het
Tapt1	C	T	5: 44,336,332 (GRCm39)	V446M	probably damaging	Het
Tent5c	A	T	3: 100,379,946 (GRCm39)	M270K	probably damaging	Het
Tnni3k	A	C	3: 154,667,663 (GRCm39)	V250G	probably damaging	Het
Ttll8	C	T	15: 88,799,848 (GRCm39)	G531E	possibly damaging	Het
U2surp	T	A	9: 95,346,472 (GRCm39)	E862D	possibly damaging	Het
U2surp	A	G	9: 95,364,234 (GRCm39)	F561L	probably damaging	Het
Unc5d	A	G	8: 29,142,819 (GRCm39)	Y878H	probably damaging	Het
Ust	A	G	10: 8,173,842 (GRCm39)	M221T	probably benign	Het
Wasf3	T	C	5: 146,392,401 (GRCm39)	F157S	probably damaging	Het
Wdr64	G	A	1: 175,533,637 (GRCm39)	C91Y	probably damaging	Het
Zan	T	C	5: 137,422,368 (GRCm39)	Y2750C	unknown	Het

Other mutations in Tex56

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02726:Tex56	APN	13	35,136,943 (GRCm39)	intron	probably benign
IGL03241:Tex56	APN	13	35,128,313 (GRCm39)	missense	probably damaging	0.98
R0324:Tex56	UTSW	13	35,108,596 (GRCm39)	missense	probably benign
R0394:Tex56	UTSW	13	35,116,636 (GRCm39)	splice site	probably benign
R0409:Tex56	UTSW	13	35,108,532 (GRCm39)	missense	probably benign	0.08
R1639:Tex56	UTSW	13	35,128,233 (GRCm39)	missense	possibly damaging	0.93
R1861:Tex56	UTSW	13	35,116,490 (GRCm39)	missense	possibly damaging	0.80
R2054:Tex56	UTSW	13	35,108,574 (GRCm39)	missense	probably damaging	0.99
R4625:Tex56	UTSW	13	35,116,448 (GRCm39)	missense	probably damaging	1.00
R4932:Tex56	UTSW	13	35,116,613 (GRCm39)	missense	possibly damaging	0.95
R5875:Tex56	UTSW	13	35,116,429 (GRCm39)	missense	probably damaging	0.99
R7837:Tex56	UTSW	13	35,128,359 (GRCm39)	missense	possibly damaging	0.85
R8836:Tex56	UTSW	13	35,116,526 (GRCm39)	missense	probably damaging	0.99
R9266:Tex56	UTSW	13	35,116,569 (GRCm39)	missense	possibly damaging	0.95

Posted On

2014-05-07