Incidental Mutation 'IGL02034:Gm17019'
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm17019
Ensembl Gene ENSMUSG00000091897
Gene Namepredicted gene 17019
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.196) question?
Stock #IGL02034
Quality Score
Chromosomal Location15028950-15032998 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 15030252 bp
Amino Acid Change Isoleucine to Threonine at position 182 (I182T)
Ref Sequence ENSEMBL: ENSMUSP00000127520 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000167908]
Predicted Effect possibly damaging
Transcript: ENSMUST00000167908
AA Change: I182T

PolyPhen 2 Score 0.948 (Sensitivity: 0.79; Specificity: 0.95)
SMART Domains Protein: ENSMUSP00000127520
Gene: ENSMUSG00000091897
AA Change: I182T

Pfam:Takusan 50 134 1.1e-30 PFAM
low complexity region 247 254 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 33 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
9930021J03Rik A G 19: 29,716,859 S1745P possibly damaging Het
Bcor A G X: 12,039,259 S1556P possibly damaging Het
Ccdc6 T A 10: 70,169,148 I241N probably benign Het
Cd81 T C 7: 143,066,249 I48T probably damaging Het
Cfap52 A G 11: 67,946,292 probably null Het
Cfap54 T C 10: 93,061,485 M264V probably damaging Het
Cmya5 G A 13: 93,084,535 probably benign Het
Csn2 A G 5: 87,696,082 probably benign Het
Cyfip1 G A 7: 55,898,353 R567Q probably damaging Het
Ehbp1 A G 11: 22,285,486 probably null Het
Ermp1 G A 19: 29,645,959 probably benign Het
Erv3 C T 2: 131,856,014 V142I possibly damaging Het
Fzd2 A G 11: 102,604,904 N58S probably damaging Het
Gcm2 G A 13: 41,105,793 R67C probably damaging Het
Gpr45 T C 1: 43,033,318 *374Q probably null Het
Haus8 T C 8: 71,255,558 N165S probably damaging Het
Hoxd4 T A 2: 74,728,406 L191Q probably damaging Het
I830077J02Rik A G 3: 105,927,249 probably benign Het
Lpl T C 8: 68,880,772 L7P possibly damaging Het
Lrp1b T A 2: 41,268,370 K1612* probably null Het
Myh14 G T 7: 44,616,293 A1546D possibly damaging Het
Nbea A G 3: 55,968,156 S1698P probably damaging Het
Olfr1217 C T 2: 89,023,671 V111M probably benign Het
Olfr470 G A 7: 107,845,178 T185I probably benign Het
Olfr676 C A 7: 105,035,390 T64N probably benign Het
Olfr9 A T 10: 128,990,701 Q263L probably benign Het
Otog A T 7: 46,295,993 K40* probably null Het
Rgma C A 7: 73,417,433 H145Q probably damaging Het
Rpgrip1l A T 8: 91,251,148 probably null Het
Ssxb2 T A X: 8,458,504 probably benign Het
Tmem175 C T 5: 108,642,136 T118I probably damaging Het
Wdhd1 A G 14: 47,261,351 V542A probably benign Het
Zfp977 G A 7: 42,580,712 P130S probably damaging Het
Other mutations in Gm17019
AlleleSourceChrCoordTypePredicted EffectPPH Score
R3617:Gm17019 UTSW 5 15031067 missense possibly damaging 0.88
R5175:Gm17019 UTSW 5 15032803 missense possibly damaging 0.92
R5520:Gm17019 UTSW 5 15032805 missense possibly damaging 0.77
Posted On2014-05-07