Incidental Mutation 'IGL02056:Ccdc148'
ID185245
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Ccdc148
Ensembl Gene ENSMUSG00000036641
Gene Namecoiled-coil domain containing 148
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.171) question?
Stock #IGL02056
Quality Score
Status
Chromosome2
Chromosomal Location58821070-59160683 bp(-) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to G at 59004069 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000153944 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000077687] [ENSMUST00000226455]
Predicted Effect probably benign
Transcript: ENSMUST00000077687
SMART Domains Protein: ENSMUSP00000076871
Gene: ENSMUSG00000036641

DomainStartEndE-ValueType
coiled coil region 173 195 N/A INTRINSIC
coiled coil region 289 353 N/A INTRINSIC
low complexity region 369 382 N/A INTRINSIC
coiled coil region 401 438 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000226455
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 26 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2310050C09Rik T A 3: 92,868,893 Q161L probably benign Het
Atg101 T C 15: 101,290,337 S108P probably damaging Het
BB014433 A T 8: 15,042,435 C139* probably null Het
Cacna1s A G 1: 136,119,000 N1808S probably benign Het
Dnah7a T G 1: 53,504,342 N2223T probably benign Het
Fgl2 T A 5: 21,375,545 I295K probably damaging Het
Foxj3 T C 4: 119,585,757 I126T probably damaging Het
Gm4540 T A 3: 106,034,740 probably benign Het
Hps5 T G 7: 46,788,182 K156N probably damaging Het
Hsp90aa1 T C 12: 110,694,015 probably benign Het
Il12rb1 C T 8: 70,811,187 R131* probably null Het
Itgb2l T C 16: 96,427,689 E438G probably damaging Het
Nbeal2 A T 9: 110,627,324 L2379Q probably benign Het
Neurl4 T C 11: 69,905,790 V481A probably damaging Het
Nos1ap A G 1: 170,318,623 F454S possibly damaging Het
Pik3r5 G T 11: 68,490,855 G242C possibly damaging Het
Pkd1l3 A G 8: 109,631,378 N834S probably benign Het
Prkar2b A G 12: 31,975,910 probably benign Het
Pusl1 T C 4: 155,890,572 T191A probably benign Het
Rasal2 A G 1: 157,299,261 V51A probably damaging Het
Rsc1a1 T A 4: 141,685,485 I39F probably benign Het
Slc2a3 G A 6: 122,735,478 P269L probably damaging Het
Sntb1 C T 15: 55,648,039 G383D possibly damaging Het
Washc5 T C 15: 59,350,336 T547A possibly damaging Het
Zfr T C 15: 12,154,447 V572A probably damaging Het
Zmym6 T A 4: 127,103,414 N275K probably damaging Het
Other mutations in Ccdc148
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01362:Ccdc148 APN 2 58829799 missense probably benign 0.00
IGL02470:Ccdc148 APN 2 59001899 missense probably damaging 0.96
R0068:Ccdc148 UTSW 2 58827617 missense probably benign
R0068:Ccdc148 UTSW 2 58827617 missense probably benign
R0348:Ccdc148 UTSW 2 59004072 splice site probably null
R1464:Ccdc148 UTSW 2 58906362 nonsense probably null
R1464:Ccdc148 UTSW 2 58934443 missense probably damaging 1.00
R1464:Ccdc148 UTSW 2 58906362 nonsense probably null
R1464:Ccdc148 UTSW 2 58934443 missense probably damaging 1.00
R1675:Ccdc148 UTSW 2 58980554 missense probably damaging 0.96
R1677:Ccdc148 UTSW 2 59002164 missense probably damaging 1.00
R1832:Ccdc148 UTSW 2 59001899 missense probably damaging 0.96
R1918:Ccdc148 UTSW 2 58982899 missense probably damaging 1.00
R2114:Ccdc148 UTSW 2 59002116 missense probably damaging 1.00
R2115:Ccdc148 UTSW 2 59002116 missense probably damaging 1.00
R4657:Ccdc148 UTSW 2 59001888 missense probably benign 0.04
R4921:Ccdc148 UTSW 2 58829802 missense probably damaging 1.00
R5022:Ccdc148 UTSW 2 58827632 missense probably damaging 1.00
R5809:Ccdc148 UTSW 2 58823645 missense probably damaging 1.00
R6164:Ccdc148 UTSW 2 58823633 missense probably damaging 1.00
R6952:Ccdc148 UTSW 2 58823645 missense probably damaging 1.00
R6987:Ccdc148 UTSW 2 58982914 missense probably damaging 1.00
X0062:Ccdc148 UTSW 2 59003448 missense probably damaging 0.98
Posted On2014-05-07