Incidental Mutation 'IGL02051:Vmn1r68'
| ID |
186111 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r68
|
| Ensembl Gene |
ENSMUSG00000047031 |
| Gene Name |
vomeronasal 1 receptor 68 |
| Synonyms |
Gm6898 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.060)
|
| Stock # |
IGL02051
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
7 |
| Chromosomal Location |
10261137-10262096 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 10261948 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Glutamic Acid
at position 50
(V50E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000050927
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000058362]
|
| AlphaFold |
E9Q0V3 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000058362
AA Change: V50E
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000050927
Gene: ENSMUSG00000047031
AA Change: V50E
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:V1R
|
49 |
306 |
2e-33 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 21 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Cacul1 |
T |
C |
19: 60,531,504 (GRCm39) |
D255G |
probably damaging |
Het |
| Chi3l1 |
T |
C |
1: 134,111,887 (GRCm39) |
S94P |
probably damaging |
Het |
| Defa38 |
A |
G |
8: 21,585,275 (GRCm39) |
|
probably benign |
Het |
| Dzip3 |
T |
C |
16: 48,792,617 (GRCm39) |
T223A |
probably benign |
Het |
| Firrm |
T |
C |
1: 163,785,091 (GRCm39) |
T763A |
probably benign |
Het |
| Gfra3 |
T |
C |
18: 34,828,894 (GRCm39) |
T167A |
possibly damaging |
Het |
| Glb1l3 |
T |
C |
9: 26,736,464 (GRCm39) |
I533V |
probably benign |
Het |
| Gm11437 |
T |
A |
11: 84,043,592 (GRCm39) |
Q233L |
probably benign |
Het |
| Hif1an |
A |
G |
19: 44,551,829 (GRCm39) |
Y93C |
probably damaging |
Het |
| Hspg2 |
A |
G |
4: 137,295,700 (GRCm39) |
|
probably benign |
Het |
| Ints15 |
A |
G |
5: 143,293,737 (GRCm39) |
C247R |
probably damaging |
Het |
| Mak |
G |
A |
13: 41,195,558 (GRCm39) |
A385V |
probably benign |
Het |
| Mical2 |
G |
T |
7: 111,980,597 (GRCm39) |
K190N |
probably benign |
Het |
| Moxd1 |
A |
G |
10: 24,128,916 (GRCm39) |
|
probably null |
Het |
| Ptpn5 |
A |
G |
7: 46,732,507 (GRCm39) |
|
probably null |
Het |
| Ryr1 |
A |
G |
7: 28,771,083 (GRCm39) |
Y2614H |
probably benign |
Het |
| Sema3e |
T |
A |
5: 14,274,324 (GRCm39) |
Y192N |
possibly damaging |
Het |
| Smpd4 |
T |
C |
16: 17,444,382 (GRCm39) |
L145P |
probably damaging |
Het |
| Tesk2 |
A |
G |
4: 116,608,381 (GRCm39) |
E101G |
probably damaging |
Het |
| Vpreb3 |
G |
A |
10: 75,784,244 (GRCm39) |
|
probably null |
Het |
| Vps72 |
T |
C |
3: 95,030,040 (GRCm39) |
L353P |
possibly damaging |
Het |
|
| Other mutations in Vmn1r68 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01892:Vmn1r68
|
APN |
7 |
10,261,334 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
IGL02112:Vmn1r68
|
APN |
7 |
10,261,787 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02619:Vmn1r68
|
APN |
7 |
10,261,603 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL03033:Vmn1r68
|
APN |
7 |
10,262,074 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03184:Vmn1r68
|
APN |
7 |
10,261,799 (GRCm39) |
missense |
probably benign |
0.16 |
|
PIT4354001:Vmn1r68
|
UTSW |
7 |
10,261,958 (GRCm39) |
missense |
probably benign |
|
|
R0141:Vmn1r68
|
UTSW |
7 |
10,261,252 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0359:Vmn1r68
|
UTSW |
7 |
10,261,201 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0634:Vmn1r68
|
UTSW |
7 |
10,261,162 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1731:Vmn1r68
|
UTSW |
7 |
10,261,802 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2021:Vmn1r68
|
UTSW |
7 |
10,261,918 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2022:Vmn1r68
|
UTSW |
7 |
10,261,918 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2243:Vmn1r68
|
UTSW |
7 |
10,262,089 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2262:Vmn1r68
|
UTSW |
7 |
10,261,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3877:Vmn1r68
|
UTSW |
7 |
10,261,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4470:Vmn1r68
|
UTSW |
7 |
10,261,275 (GRCm39) |
missense |
probably benign |
0.23 |
|
R4843:Vmn1r68
|
UTSW |
7 |
10,261,904 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5198:Vmn1r68
|
UTSW |
7 |
10,261,723 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5835:Vmn1r68
|
UTSW |
7 |
10,261,747 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R5906:Vmn1r68
|
UTSW |
7 |
10,261,550 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6015:Vmn1r68
|
UTSW |
7 |
10,261,616 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7073:Vmn1r68
|
UTSW |
7 |
10,261,778 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7614:Vmn1r68
|
UTSW |
7 |
10,261,553 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7699:Vmn1r68
|
UTSW |
7 |
10,261,559 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7700:Vmn1r68
|
UTSW |
7 |
10,261,559 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7912:Vmn1r68
|
UTSW |
7 |
10,261,237 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8166:Vmn1r68
|
UTSW |
7 |
10,261,888 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8426:Vmn1r68
|
UTSW |
7 |
10,261,382 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9466:Vmn1r68
|
UTSW |
7 |
10,261,417 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9466:Vmn1r68
|
UTSW |
7 |
10,261,317 (GRCm39) |
nonsense |
probably null |
|
|
| Posted On |
2014-05-07 |
Incidental Mutation