Incidental Mutation 'R1672:Urb1'
| ID |
187754 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Urb1
|
| Ensembl Gene |
ENSMUSG00000039929 |
| Gene Name |
URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| Synonyms |
5730405K23Rik, 4921511H13Rik |
| MMRRC Submission |
039708-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1672 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
16 |
| Chromosomal Location |
90548415-90607301 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 90584285 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Serine
at position 566
(C566S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000114717
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000140920]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000140920
AA Change: C566S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000114717
Gene: ENSMUSG00000039929
AA Change: C566S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
20 |
N/A |
INTRINSIC |
|
Pfam:Npa1
|
78 |
396 |
1.5e-86 |
PFAM |
|
low complexity region
|
751 |
761 |
N/A |
INTRINSIC |
|
low complexity region
|
955 |
966 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1137 |
N/A |
INTRINSIC |
|
low complexity region
|
1360 |
1375 |
N/A |
INTRINSIC |
|
Pfam:NopRA1
|
1670 |
1859 |
3.6e-60 |
PFAM |
|
low complexity region
|
2029 |
2040 |
N/A |
INTRINSIC |
|
low complexity region
|
2092 |
2111 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142955
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.4%
- 20x: 92.7%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 103 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310079G19Rik |
G |
A |
16: 88,424,096 (GRCm39) |
Q132* |
probably null |
Het |
| Aadacl4 |
T |
A |
4: 144,349,889 (GRCm39) |
L382* |
probably null |
Het |
| Afg3l2 |
A |
G |
18: 67,540,493 (GRCm39) |
I672T |
probably benign |
Het |
| Aftph |
A |
T |
11: 20,676,762 (GRCm39) |
D282E |
probably benign |
Het |
| Agpat5 |
A |
G |
8: 18,920,930 (GRCm39) |
N161S |
probably benign |
Het |
| Alpk2 |
C |
T |
18: 65,414,030 (GRCm39) |
E1562K |
probably damaging |
Het |
| Anxa2 |
TCCC |
TCC |
9: 69,397,036 (GRCm39) |
|
probably null |
Het |
| Apobr |
A |
G |
7: 126,186,723 (GRCm39) |
R745G |
probably benign |
Het |
| Arrdc5 |
T |
C |
17: 56,607,144 (GRCm39) |
T34A |
possibly damaging |
Het |
| Astl |
T |
C |
2: 127,189,163 (GRCm39) |
L163P |
probably damaging |
Het |
| Atf7ip2 |
A |
T |
16: 10,027,005 (GRCm39) |
H91L |
probably damaging |
Het |
| Atp13a3 |
A |
T |
16: 30,151,092 (GRCm39) |
S1073T |
possibly damaging |
Het |
| Bcl2a1a |
A |
T |
9: 88,839,503 (GRCm39) |
I134L |
probably damaging |
Het |
| Brinp1 |
T |
C |
4: 68,747,520 (GRCm39) |
|
probably null |
Het |
| Capn9 |
A |
G |
8: 125,340,570 (GRCm39) |
N578S |
probably benign |
Het |
| Casp2 |
T |
A |
6: 42,245,842 (GRCm39) |
D166E |
probably damaging |
Het |
| Ccr1l1 |
A |
T |
9: 123,777,544 (GRCm39) |
I301N |
probably damaging |
Het |
| Chtop |
T |
A |
3: 90,414,874 (GRCm39) |
T15S |
probably damaging |
Het |
| Coq5 |
T |
A |
5: 115,417,975 (GRCm39) |
|
probably null |
Het |
| Crbn |
G |
A |
6: 106,772,886 (GRCm39) |
P34L |
probably damaging |
Het |
| Crisp1 |
G |
T |
17: 40,619,760 (GRCm39) |
D59E |
possibly damaging |
Het |
| Cyp4f14 |
A |
T |
17: 33,128,210 (GRCm39) |
D268E |
probably benign |
Het |
| D5Ertd579e |
T |
C |
5: 36,770,621 (GRCm39) |
D1258G |
possibly damaging |
Het |
| Dcp1b |
T |
C |
6: 119,194,872 (GRCm39) |
S531P |
probably benign |
Het |
| Defb25 |
T |
C |
2: 152,464,410 (GRCm39) |
M45V |
probably benign |
Het |
| Dffa |
T |
C |
4: 149,190,702 (GRCm39) |
L77P |
probably damaging |
Het |
| Dixdc1 |
T |
C |
9: 50,601,164 (GRCm39) |
Q361R |
probably damaging |
Het |
| Dnah1 |
A |
G |
14: 30,998,157 (GRCm39) |
L2560P |
probably damaging |
Het |
| Fabp5 |
A |
G |
3: 10,080,601 (GRCm39) |
T108A |
probably benign |
Het |
| Fam149a |
T |
G |
8: 45,792,411 (GRCm39) |
|
probably null |
Het |
| Fam20c |
A |
G |
5: 138,793,056 (GRCm39) |
Y430C |
probably damaging |
Het |
| Fat1 |
A |
G |
8: 45,489,872 (GRCm39) |
T3595A |
probably damaging |
Het |
| Fbp1 |
A |
G |
13: 63,015,245 (GRCm39) |
Y245H |
probably damaging |
Het |
| Frem1 |
C |
T |
4: 82,917,128 (GRCm39) |
R605H |
probably benign |
Het |
| Fscb |
A |
G |
12: 64,518,292 (GRCm39) |
I1058T |
unknown |
Het |
| Fyb2 |
A |
G |
4: 104,808,059 (GRCm39) |
K373R |
probably benign |
Het |
| Ggta1 |
A |
T |
2: 35,292,145 (GRCm39) |
Y387* |
probably null |
Het |
| Gm18856 |
T |
C |
13: 14,140,342 (GRCm39) |
|
probably benign |
Het |
| Gm572 |
T |
C |
4: 148,752,966 (GRCm39) |
S282P |
possibly damaging |
Het |
| Gpd2 |
A |
T |
2: 57,247,712 (GRCm39) |
I552F |
probably damaging |
Het |
| Grk5 |
T |
C |
19: 61,074,653 (GRCm39) |
|
probably null |
Het |
| Hivep1 |
T |
C |
13: 42,313,760 (GRCm39) |
V2000A |
probably damaging |
Het |
| Ipo5 |
C |
T |
14: 121,170,714 (GRCm39) |
L466F |
probably damaging |
Het |
| Itgb1 |
G |
A |
8: 129,458,526 (GRCm39) |
S785N |
probably damaging |
Het |
| Itpr3 |
G |
A |
17: 27,307,987 (GRCm39) |
R258K |
probably benign |
Het |
| Kcnk12 |
A |
G |
17: 88,053,747 (GRCm39) |
V305A |
probably benign |
Het |
| Klf5 |
C |
T |
14: 99,538,986 (GRCm39) |
T133I |
probably damaging |
Het |
| Lrig2 |
A |
G |
3: 104,399,128 (GRCm39) |
I178T |
probably damaging |
Het |
| Lyrm4 |
A |
T |
13: 36,276,907 (GRCm39) |
M30K |
probably benign |
Het |
| Mpv17 |
A |
G |
5: 31,311,063 (GRCm39) |
Y7H |
probably damaging |
Het |
| Mrps22 |
T |
C |
9: 98,478,869 (GRCm39) |
|
probably null |
Het |
| Myof |
A |
T |
19: 37,931,927 (GRCm39) |
W967R |
probably damaging |
Het |
| Naip1 |
C |
T |
13: 100,559,657 (GRCm39) |
D1116N |
probably benign |
Het |
| Or1e33 |
T |
C |
11: 73,738,781 (GRCm39) |
T57A |
probably benign |
Het |
| Or6c66b |
C |
A |
10: 129,376,561 (GRCm39) |
H52N |
probably benign |
Het |
| Or8g50 |
G |
A |
9: 39,648,492 (GRCm39) |
C127Y |
probably damaging |
Het |
| Or9k2b |
T |
C |
10: 130,016,261 (GRCm39) |
T163A |
probably benign |
Het |
| Ovol2 |
T |
C |
2: 144,147,710 (GRCm39) |
Y180C |
probably damaging |
Het |
| Pacs1 |
T |
C |
19: 5,202,337 (GRCm39) |
S418G |
probably benign |
Het |
| Pcdh1 |
T |
C |
18: 38,325,233 (GRCm39) |
E903G |
probably damaging |
Het |
| Pcdhb15 |
A |
T |
18: 37,607,713 (GRCm39) |
Y315F |
probably damaging |
Het |
| Pex1 |
T |
C |
5: 3,676,085 (GRCm39) |
L891P |
probably damaging |
Het |
| Potefam1 |
T |
A |
2: 111,051,119 (GRCm39) |
M226L |
probably benign |
Het |
| Ppfia2 |
G |
A |
10: 106,666,429 (GRCm39) |
M378I |
possibly damaging |
Het |
| Ppp1r9a |
T |
A |
6: 5,143,491 (GRCm39) |
|
probably null |
Het |
| Prm3 |
T |
C |
16: 10,608,563 (GRCm39) |
E64G |
possibly damaging |
Het |
| Prmt6 |
T |
C |
3: 110,157,887 (GRCm39) |
D134G |
possibly damaging |
Het |
| Prss42 |
G |
A |
9: 110,629,996 (GRCm39) |
G250D |
probably damaging |
Het |
| Pwwp2b |
G |
A |
7: 138,834,747 (GRCm39) |
V63I |
probably benign |
Het |
| Rbm17 |
T |
C |
2: 11,590,530 (GRCm39) |
D375G |
possibly damaging |
Het |
| Rhbdl1 |
A |
T |
17: 26,055,383 (GRCm39) |
|
probably null |
Het |
| Rims2 |
T |
A |
15: 39,155,584 (GRCm39) |
D128E |
probably benign |
Het |
| Rock2 |
A |
G |
12: 17,015,653 (GRCm39) |
K850R |
probably benign |
Het |
| Rreb1 |
T |
C |
13: 38,114,513 (GRCm39) |
I624T |
probably benign |
Het |
| Rrp36 |
A |
T |
17: 46,983,340 (GRCm39) |
D91E |
probably damaging |
Het |
| Scn7a |
C |
T |
2: 66,527,944 (GRCm39) |
D849N |
possibly damaging |
Het |
| Sec24a |
A |
T |
11: 51,634,775 (GRCm39) |
Y50* |
probably null |
Het |
| Sh2d4b |
A |
G |
14: 40,614,921 (GRCm39) |
M1T |
probably null |
Het |
| Slc4a7 |
A |
G |
14: 14,760,247 (GRCm38) |
I561V |
possibly damaging |
Het |
| Slc7a12 |
T |
C |
3: 14,564,337 (GRCm39) |
V70A |
possibly damaging |
Het |
| Slfnl1 |
A |
T |
4: 120,392,972 (GRCm39) |
I355F |
probably damaging |
Het |
| Spata2 |
C |
T |
2: 167,325,439 (GRCm39) |
R460H |
probably damaging |
Het |
| Stk11ip |
C |
T |
1: 75,505,629 (GRCm39) |
Q433* |
probably null |
Het |
| Susd1 |
T |
C |
4: 59,411,395 (GRCm39) |
Y146C |
probably damaging |
Het |
| Susd5 |
A |
T |
9: 113,897,890 (GRCm39) |
D115V |
probably damaging |
Het |
| Tas2r110 |
T |
A |
6: 132,845,029 (GRCm39) |
V20E |
probably damaging |
Het |
| Tbc1d4 |
T |
C |
14: 101,712,651 (GRCm39) |
Y694C |
possibly damaging |
Het |
| Tmem131 |
T |
C |
1: 36,863,840 (GRCm39) |
E640G |
probably damaging |
Het |
| Togaram1 |
A |
G |
12: 65,068,342 (GRCm39) |
T1782A |
probably benign |
Het |
| Trim24 |
T |
C |
6: 37,892,214 (GRCm39) |
L249P |
probably damaging |
Het |
| Ttf1 |
T |
C |
2: 28,957,164 (GRCm39) |
I478T |
probably damaging |
Het |
| Upf2 |
T |
A |
2: 6,044,908 (GRCm39) |
|
probably null |
Het |
| Vmn1r191 |
T |
C |
13: 22,363,262 (GRCm39) |
N164S |
probably benign |
Het |
| Vmn2r81 |
T |
A |
10: 79,104,112 (GRCm39) |
V245E |
probably damaging |
Het |
| Vwce |
T |
A |
19: 10,630,459 (GRCm39) |
F506Y |
possibly damaging |
Het |
| Wnt8b |
T |
C |
19: 44,499,715 (GRCm39) |
F155L |
probably damaging |
Het |
| Xrra1 |
A |
T |
7: 99,547,647 (GRCm39) |
I279F |
probably benign |
Het |
| Zfp229 |
T |
C |
17: 21,964,828 (GRCm39) |
S353P |
probably damaging |
Het |
| Zfp607b |
C |
T |
7: 27,391,948 (GRCm39) |
H8Y |
possibly damaging |
Het |
| Zfp933 |
A |
T |
4: 147,910,476 (GRCm39) |
H373Q |
probably damaging |
Het |
| Zfp938 |
A |
G |
10: 82,060,982 (GRCm39) |
L546P |
probably benign |
Het |
| Zfp988 |
C |
T |
4: 147,415,739 (GRCm39) |
R58C |
probably benign |
Het |
| Zkscan14 |
C |
T |
5: 145,138,464 (GRCm39) |
V8I |
probably benign |
Het |
|
| Other mutations in Urb1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00715:Urb1
|
APN |
16 |
90,550,209 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00915:Urb1
|
APN |
16 |
90,575,986 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
IGL01108:Urb1
|
APN |
16 |
90,589,702 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01122:Urb1
|
APN |
16 |
90,601,346 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL01387:Urb1
|
APN |
16 |
90,554,649 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL01484:Urb1
|
APN |
16 |
90,574,448 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL01606:Urb1
|
APN |
16 |
90,557,347 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01989:Urb1
|
APN |
16 |
90,566,474 (GRCm39) |
splice site |
probably benign |
|
|
IGL02516:Urb1
|
APN |
16 |
90,569,583 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
IGL03018:Urb1
|
APN |
16 |
90,585,044 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL03165:Urb1
|
APN |
16 |
90,577,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03216:Urb1
|
APN |
16 |
90,585,002 (GRCm39) |
missense |
probably benign |
0.00 |
|
H8562:Urb1
|
UTSW |
16 |
90,566,357 (GRCm39) |
missense |
probably benign |
0.08 |
|
H8786:Urb1
|
UTSW |
16 |
90,566,357 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0064:Urb1
|
UTSW |
16 |
90,576,028 (GRCm39) |
missense |
probably benign |
|
|
R0064:Urb1
|
UTSW |
16 |
90,576,028 (GRCm39) |
missense |
probably benign |
|
|
R0359:Urb1
|
UTSW |
16 |
90,588,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0386:Urb1
|
UTSW |
16 |
90,593,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0508:Urb1
|
UTSW |
16 |
90,580,150 (GRCm39) |
splice site |
probably benign |
|
|
R0517:Urb1
|
UTSW |
16 |
90,574,310 (GRCm39) |
nonsense |
probably null |
|
|
R0704:Urb1
|
UTSW |
16 |
90,573,095 (GRCm39) |
missense |
probably benign |
0.31 |
|
R0755:Urb1
|
UTSW |
16 |
90,576,026 (GRCm39) |
missense |
probably benign |
|
|
R0755:Urb1
|
UTSW |
16 |
90,570,982 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0783:Urb1
|
UTSW |
16 |
90,607,185 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R0833:Urb1
|
UTSW |
16 |
90,592,336 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0836:Urb1
|
UTSW |
16 |
90,592,336 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0970:Urb1
|
UTSW |
16 |
90,566,335 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1144:Urb1
|
UTSW |
16 |
90,573,206 (GRCm39) |
splice site |
probably null |
|
|
R1344:Urb1
|
UTSW |
16 |
90,566,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1418:Urb1
|
UTSW |
16 |
90,566,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1453:Urb1
|
UTSW |
16 |
90,593,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1470:Urb1
|
UTSW |
16 |
90,548,902 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1470:Urb1
|
UTSW |
16 |
90,548,902 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1520:Urb1
|
UTSW |
16 |
90,571,633 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1521:Urb1
|
UTSW |
16 |
90,550,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1598:Urb1
|
UTSW |
16 |
90,574,328 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1617:Urb1
|
UTSW |
16 |
90,557,340 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1625:Urb1
|
UTSW |
16 |
90,570,936 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1640:Urb1
|
UTSW |
16 |
90,569,514 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1664:Urb1
|
UTSW |
16 |
90,584,970 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1694:Urb1
|
UTSW |
16 |
90,563,928 (GRCm39) |
missense |
probably benign |
|
|
R1856:Urb1
|
UTSW |
16 |
90,558,583 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2001:Urb1
|
UTSW |
16 |
90,559,232 (GRCm39) |
missense |
probably benign |
0.30 |
|
R2196:Urb1
|
UTSW |
16 |
90,571,144 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2850:Urb1
|
UTSW |
16 |
90,571,144 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3009:Urb1
|
UTSW |
16 |
90,571,686 (GRCm39) |
missense |
probably benign |
0.09 |
|
R3104:Urb1
|
UTSW |
16 |
90,592,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3105:Urb1
|
UTSW |
16 |
90,592,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3106:Urb1
|
UTSW |
16 |
90,592,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3160:Urb1
|
UTSW |
16 |
90,594,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3162:Urb1
|
UTSW |
16 |
90,594,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3900:Urb1
|
UTSW |
16 |
90,580,264 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4014:Urb1
|
UTSW |
16 |
90,566,353 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4036:Urb1
|
UTSW |
16 |
90,584,974 (GRCm39) |
missense |
probably benign |
|
|
R4332:Urb1
|
UTSW |
16 |
90,571,425 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4448:Urb1
|
UTSW |
16 |
90,566,282 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4581:Urb1
|
UTSW |
16 |
90,585,034 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4593:Urb1
|
UTSW |
16 |
90,584,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4610:Urb1
|
UTSW |
16 |
90,573,159 (GRCm39) |
missense |
probably benign |
0.43 |
|
R4659:Urb1
|
UTSW |
16 |
90,573,017 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4672:Urb1
|
UTSW |
16 |
90,569,522 (GRCm39) |
missense |
probably benign |
|
|
R4681:Urb1
|
UTSW |
16 |
90,601,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4771:Urb1
|
UTSW |
16 |
90,550,406 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4790:Urb1
|
UTSW |
16 |
90,566,443 (GRCm39) |
nonsense |
probably null |
|
|
R4798:Urb1
|
UTSW |
16 |
90,554,715 (GRCm39) |
missense |
probably benign |
0.12 |
|
R4809:Urb1
|
UTSW |
16 |
90,556,730 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4850:Urb1
|
UTSW |
16 |
90,592,302 (GRCm39) |
nonsense |
probably null |
|
|
R4916:Urb1
|
UTSW |
16 |
90,580,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4969:Urb1
|
UTSW |
16 |
90,602,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5032:Urb1
|
UTSW |
16 |
90,553,059 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5111:Urb1
|
UTSW |
16 |
90,548,905 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5122:Urb1
|
UTSW |
16 |
90,548,983 (GRCm39) |
nonsense |
probably null |
|
|
R5184:Urb1
|
UTSW |
16 |
90,580,162 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5199:Urb1
|
UTSW |
16 |
90,589,636 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5436:Urb1
|
UTSW |
16 |
90,589,650 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5767:Urb1
|
UTSW |
16 |
90,573,051 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5812:Urb1
|
UTSW |
16 |
90,601,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5872:Urb1
|
UTSW |
16 |
90,569,652 (GRCm39) |
nonsense |
probably null |
|
|
R6052:Urb1
|
UTSW |
16 |
90,559,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6063:Urb1
|
UTSW |
16 |
90,585,985 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6065:Urb1
|
UTSW |
16 |
90,600,220 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6181:Urb1
|
UTSW |
16 |
90,575,982 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6268:Urb1
|
UTSW |
16 |
90,550,807 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6429:Urb1
|
UTSW |
16 |
90,559,318 (GRCm39) |
splice site |
probably null |
|
|
R6572:Urb1
|
UTSW |
16 |
90,584,302 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6606:Urb1
|
UTSW |
16 |
90,607,156 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6730:Urb1
|
UTSW |
16 |
90,575,971 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6838:Urb1
|
UTSW |
16 |
90,578,994 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7237:Urb1
|
UTSW |
16 |
90,588,054 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7238:Urb1
|
UTSW |
16 |
90,549,003 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7339:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7341:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7361:Urb1
|
UTSW |
16 |
90,571,656 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7365:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7366:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7440:Urb1
|
UTSW |
16 |
90,584,296 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7530:Urb1
|
UTSW |
16 |
90,558,522 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7553:Urb1
|
UTSW |
16 |
90,589,752 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7557:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7603:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7607:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7609:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7610:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7612:Urb1
|
UTSW |
16 |
90,594,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7613:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7684:Urb1
|
UTSW |
16 |
90,583,006 (GRCm39) |
nonsense |
probably null |
|
|
R8029:Urb1
|
UTSW |
16 |
90,576,040 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R8324:Urb1
|
UTSW |
16 |
90,588,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8680:Urb1
|
UTSW |
16 |
90,571,513 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8785:Urb1
|
UTSW |
16 |
90,600,311 (GRCm39) |
missense |
probably benign |
0.07 |
|
R8914:Urb1
|
UTSW |
16 |
90,607,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8959:Urb1
|
UTSW |
16 |
90,571,005 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9005:Urb1
|
UTSW |
16 |
90,550,678 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9126:Urb1
|
UTSW |
16 |
90,566,290 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9195:Urb1
|
UTSW |
16 |
90,589,638 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9276:Urb1
|
UTSW |
16 |
90,569,463 (GRCm39) |
splice site |
probably benign |
|
|
R9534:Urb1
|
UTSW |
16 |
90,583,096 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
Z1177:Urb1
|
UTSW |
16 |
90,571,750 (GRCm39) |
missense |
probably benign |
0.05 |
|
Z1177:Urb1
|
UTSW |
16 |
90,550,771 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCACATCTGCTGATAAACTGCCCAC -3'
(R):5'- AGGCTTAAGACCAGTCCCTGGAAC -3'
Sequencing Primer
(F):5'- TGCTGATAAACTGCCCACACTAC -3'
(R):5'- TGGAACAGTATCCACCCTGTTAG -3'
|
| Posted On |
2014-05-09 |
Incidental Mutation