Incidental Mutation 'R1672:Alpk2'
| ID |
187765 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Alpk2
|
| Ensembl Gene |
ENSMUSG00000032845 |
| Gene Name |
alpha-kinase 2 |
| Synonyms |
Hak |
| MMRRC Submission |
039708-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1672 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
18 |
| Chromosomal Location |
65398600-65526959 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 65414030 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Lysine
at position 1562
(E1562K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000114658
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000035548]
[ENSMUST00000141250]
|
| AlphaFold |
Q91ZB0 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000035548
AA Change: E2029K
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000048752
Gene: ENSMUSG00000032845
AA Change: E2029K
| Domain | Start | End | E-Value | Type |
|---|
|
IGc2
|
24 |
94 |
9.34e-4 |
SMART |
|
low complexity region
|
196 |
209 |
N/A |
INTRINSIC |
|
low complexity region
|
722 |
734 |
N/A |
INTRINSIC |
|
low complexity region
|
1025 |
1037 |
N/A |
INTRINSIC |
|
low complexity region
|
1337 |
1353 |
N/A |
INTRINSIC |
|
IG
|
1766 |
1849 |
2.27e-2 |
SMART |
|
Alpha_kinase
|
1879 |
2098 |
3.72e-79 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000141250
AA Change: E1562K
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000114658
Gene: ENSMUSG00000032845
AA Change: E1562K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
255 |
267 |
N/A |
INTRINSIC |
|
low complexity region
|
558 |
570 |
N/A |
INTRINSIC |
|
low complexity region
|
870 |
886 |
N/A |
INTRINSIC |
|
IG
|
1299 |
1382 |
2.27e-2 |
SMART |
|
Alpha_kinase
|
1412 |
1603 |
2.45e-56 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.4%
- 20x: 92.7%
|
| Validation Efficiency |
|
| Allele List at MGI |
All alleles(1) : Targeted, knock-out(1) |
| Other mutations in this stock |
Total: 103 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310079G19Rik |
G |
A |
16: 88,424,096 (GRCm39) |
Q132* |
probably null |
Het |
| Aadacl4 |
T |
A |
4: 144,349,889 (GRCm39) |
L382* |
probably null |
Het |
| Afg3l2 |
A |
G |
18: 67,540,493 (GRCm39) |
I672T |
probably benign |
Het |
| Aftph |
A |
T |
11: 20,676,762 (GRCm39) |
D282E |
probably benign |
Het |
| Agpat5 |
A |
G |
8: 18,920,930 (GRCm39) |
N161S |
probably benign |
Het |
| Anxa2 |
TCCC |
TCC |
9: 69,397,036 (GRCm39) |
|
probably null |
Het |
| Apobr |
A |
G |
7: 126,186,723 (GRCm39) |
R745G |
probably benign |
Het |
| Arrdc5 |
T |
C |
17: 56,607,144 (GRCm39) |
T34A |
possibly damaging |
Het |
| Astl |
T |
C |
2: 127,189,163 (GRCm39) |
L163P |
probably damaging |
Het |
| Atf7ip2 |
A |
T |
16: 10,027,005 (GRCm39) |
H91L |
probably damaging |
Het |
| Atp13a3 |
A |
T |
16: 30,151,092 (GRCm39) |
S1073T |
possibly damaging |
Het |
| Bcl2a1a |
A |
T |
9: 88,839,503 (GRCm39) |
I134L |
probably damaging |
Het |
| Brinp1 |
T |
C |
4: 68,747,520 (GRCm39) |
|
probably null |
Het |
| Capn9 |
A |
G |
8: 125,340,570 (GRCm39) |
N578S |
probably benign |
Het |
| Casp2 |
T |
A |
6: 42,245,842 (GRCm39) |
D166E |
probably damaging |
Het |
| Ccr1l1 |
A |
T |
9: 123,777,544 (GRCm39) |
I301N |
probably damaging |
Het |
| Chtop |
T |
A |
3: 90,414,874 (GRCm39) |
T15S |
probably damaging |
Het |
| Coq5 |
T |
A |
5: 115,417,975 (GRCm39) |
|
probably null |
Het |
| Crbn |
G |
A |
6: 106,772,886 (GRCm39) |
P34L |
probably damaging |
Het |
| Crisp1 |
G |
T |
17: 40,619,760 (GRCm39) |
D59E |
possibly damaging |
Het |
| Cyp4f14 |
A |
T |
17: 33,128,210 (GRCm39) |
D268E |
probably benign |
Het |
| D5Ertd579e |
T |
C |
5: 36,770,621 (GRCm39) |
D1258G |
possibly damaging |
Het |
| Dcp1b |
T |
C |
6: 119,194,872 (GRCm39) |
S531P |
probably benign |
Het |
| Defb25 |
T |
C |
2: 152,464,410 (GRCm39) |
M45V |
probably benign |
Het |
| Dffa |
T |
C |
4: 149,190,702 (GRCm39) |
L77P |
probably damaging |
Het |
| Dixdc1 |
T |
C |
9: 50,601,164 (GRCm39) |
Q361R |
probably damaging |
Het |
| Dnah1 |
A |
G |
14: 30,998,157 (GRCm39) |
L2560P |
probably damaging |
Het |
| Fabp5 |
A |
G |
3: 10,080,601 (GRCm39) |
T108A |
probably benign |
Het |
| Fam149a |
T |
G |
8: 45,792,411 (GRCm39) |
|
probably null |
Het |
| Fam20c |
A |
G |
5: 138,793,056 (GRCm39) |
Y430C |
probably damaging |
Het |
| Fat1 |
A |
G |
8: 45,489,872 (GRCm39) |
T3595A |
probably damaging |
Het |
| Fbp1 |
A |
G |
13: 63,015,245 (GRCm39) |
Y245H |
probably damaging |
Het |
| Frem1 |
C |
T |
4: 82,917,128 (GRCm39) |
R605H |
probably benign |
Het |
| Fscb |
A |
G |
12: 64,518,292 (GRCm39) |
I1058T |
unknown |
Het |
| Fyb2 |
A |
G |
4: 104,808,059 (GRCm39) |
K373R |
probably benign |
Het |
| Ggta1 |
A |
T |
2: 35,292,145 (GRCm39) |
Y387* |
probably null |
Het |
| Gm18856 |
T |
C |
13: 14,140,342 (GRCm39) |
|
probably benign |
Het |
| Gm572 |
T |
C |
4: 148,752,966 (GRCm39) |
S282P |
possibly damaging |
Het |
| Gpd2 |
A |
T |
2: 57,247,712 (GRCm39) |
I552F |
probably damaging |
Het |
| Grk5 |
T |
C |
19: 61,074,653 (GRCm39) |
|
probably null |
Het |
| Hivep1 |
T |
C |
13: 42,313,760 (GRCm39) |
V2000A |
probably damaging |
Het |
| Ipo5 |
C |
T |
14: 121,170,714 (GRCm39) |
L466F |
probably damaging |
Het |
| Itgb1 |
G |
A |
8: 129,458,526 (GRCm39) |
S785N |
probably damaging |
Het |
| Itpr3 |
G |
A |
17: 27,307,987 (GRCm39) |
R258K |
probably benign |
Het |
| Kcnk12 |
A |
G |
17: 88,053,747 (GRCm39) |
V305A |
probably benign |
Het |
| Klf5 |
C |
T |
14: 99,538,986 (GRCm39) |
T133I |
probably damaging |
Het |
| Lrig2 |
A |
G |
3: 104,399,128 (GRCm39) |
I178T |
probably damaging |
Het |
| Lyrm4 |
A |
T |
13: 36,276,907 (GRCm39) |
M30K |
probably benign |
Het |
| Mpv17 |
A |
G |
5: 31,311,063 (GRCm39) |
Y7H |
probably damaging |
Het |
| Mrps22 |
T |
C |
9: 98,478,869 (GRCm39) |
|
probably null |
Het |
| Myof |
A |
T |
19: 37,931,927 (GRCm39) |
W967R |
probably damaging |
Het |
| Naip1 |
C |
T |
13: 100,559,657 (GRCm39) |
D1116N |
probably benign |
Het |
| Or1e33 |
T |
C |
11: 73,738,781 (GRCm39) |
T57A |
probably benign |
Het |
| Or6c66b |
C |
A |
10: 129,376,561 (GRCm39) |
H52N |
probably benign |
Het |
| Or8g50 |
G |
A |
9: 39,648,492 (GRCm39) |
C127Y |
probably damaging |
Het |
| Or9k2b |
T |
C |
10: 130,016,261 (GRCm39) |
T163A |
probably benign |
Het |
| Ovol2 |
T |
C |
2: 144,147,710 (GRCm39) |
Y180C |
probably damaging |
Het |
| Pacs1 |
T |
C |
19: 5,202,337 (GRCm39) |
S418G |
probably benign |
Het |
| Pcdh1 |
T |
C |
18: 38,325,233 (GRCm39) |
E903G |
probably damaging |
Het |
| Pcdhb15 |
A |
T |
18: 37,607,713 (GRCm39) |
Y315F |
probably damaging |
Het |
| Pex1 |
T |
C |
5: 3,676,085 (GRCm39) |
L891P |
probably damaging |
Het |
| Potefam1 |
T |
A |
2: 111,051,119 (GRCm39) |
M226L |
probably benign |
Het |
| Ppfia2 |
G |
A |
10: 106,666,429 (GRCm39) |
M378I |
possibly damaging |
Het |
| Ppp1r9a |
T |
A |
6: 5,143,491 (GRCm39) |
|
probably null |
Het |
| Prm3 |
T |
C |
16: 10,608,563 (GRCm39) |
E64G |
possibly damaging |
Het |
| Prmt6 |
T |
C |
3: 110,157,887 (GRCm39) |
D134G |
possibly damaging |
Het |
| Prss42 |
G |
A |
9: 110,629,996 (GRCm39) |
G250D |
probably damaging |
Het |
| Pwwp2b |
G |
A |
7: 138,834,747 (GRCm39) |
V63I |
probably benign |
Het |
| Rbm17 |
T |
C |
2: 11,590,530 (GRCm39) |
D375G |
possibly damaging |
Het |
| Rhbdl1 |
A |
T |
17: 26,055,383 (GRCm39) |
|
probably null |
Het |
| Rims2 |
T |
A |
15: 39,155,584 (GRCm39) |
D128E |
probably benign |
Het |
| Rock2 |
A |
G |
12: 17,015,653 (GRCm39) |
K850R |
probably benign |
Het |
| Rreb1 |
T |
C |
13: 38,114,513 (GRCm39) |
I624T |
probably benign |
Het |
| Rrp36 |
A |
T |
17: 46,983,340 (GRCm39) |
D91E |
probably damaging |
Het |
| Scn7a |
C |
T |
2: 66,527,944 (GRCm39) |
D849N |
possibly damaging |
Het |
| Sec24a |
A |
T |
11: 51,634,775 (GRCm39) |
Y50* |
probably null |
Het |
| Sh2d4b |
A |
G |
14: 40,614,921 (GRCm39) |
M1T |
probably null |
Het |
| Slc4a7 |
A |
G |
14: 14,760,247 (GRCm38) |
I561V |
possibly damaging |
Het |
| Slc7a12 |
T |
C |
3: 14,564,337 (GRCm39) |
V70A |
possibly damaging |
Het |
| Slfnl1 |
A |
T |
4: 120,392,972 (GRCm39) |
I355F |
probably damaging |
Het |
| Spata2 |
C |
T |
2: 167,325,439 (GRCm39) |
R460H |
probably damaging |
Het |
| Stk11ip |
C |
T |
1: 75,505,629 (GRCm39) |
Q433* |
probably null |
Het |
| Susd1 |
T |
C |
4: 59,411,395 (GRCm39) |
Y146C |
probably damaging |
Het |
| Susd5 |
A |
T |
9: 113,897,890 (GRCm39) |
D115V |
probably damaging |
Het |
| Tas2r110 |
T |
A |
6: 132,845,029 (GRCm39) |
V20E |
probably damaging |
Het |
| Tbc1d4 |
T |
C |
14: 101,712,651 (GRCm39) |
Y694C |
possibly damaging |
Het |
| Tmem131 |
T |
C |
1: 36,863,840 (GRCm39) |
E640G |
probably damaging |
Het |
| Togaram1 |
A |
G |
12: 65,068,342 (GRCm39) |
T1782A |
probably benign |
Het |
| Trim24 |
T |
C |
6: 37,892,214 (GRCm39) |
L249P |
probably damaging |
Het |
| Ttf1 |
T |
C |
2: 28,957,164 (GRCm39) |
I478T |
probably damaging |
Het |
| Upf2 |
T |
A |
2: 6,044,908 (GRCm39) |
|
probably null |
Het |
| Urb1 |
A |
T |
16: 90,584,285 (GRCm39) |
C566S |
probably damaging |
Het |
| Vmn1r191 |
T |
C |
13: 22,363,262 (GRCm39) |
N164S |
probably benign |
Het |
| Vmn2r81 |
T |
A |
10: 79,104,112 (GRCm39) |
V245E |
probably damaging |
Het |
| Vwce |
T |
A |
19: 10,630,459 (GRCm39) |
F506Y |
possibly damaging |
Het |
| Wnt8b |
T |
C |
19: 44,499,715 (GRCm39) |
F155L |
probably damaging |
Het |
| Xrra1 |
A |
T |
7: 99,547,647 (GRCm39) |
I279F |
probably benign |
Het |
| Zfp229 |
T |
C |
17: 21,964,828 (GRCm39) |
S353P |
probably damaging |
Het |
| Zfp607b |
C |
T |
7: 27,391,948 (GRCm39) |
H8Y |
possibly damaging |
Het |
| Zfp933 |
A |
T |
4: 147,910,476 (GRCm39) |
H373Q |
probably damaging |
Het |
| Zfp938 |
A |
G |
10: 82,060,982 (GRCm39) |
L546P |
probably benign |
Het |
| Zfp988 |
C |
T |
4: 147,415,739 (GRCm39) |
R58C |
probably benign |
Het |
| Zkscan14 |
C |
T |
5: 145,138,464 (GRCm39) |
V8I |
probably benign |
Het |
|
| Other mutations in Alpk2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00468:Alpk2
|
APN |
18 |
65,438,894 (GRCm39) |
missense |
probably benign |
0.27 |
|
IGL00478:Alpk2
|
APN |
18 |
65,440,297 (GRCm39) |
nonsense |
probably null |
|
|
IGL00898:Alpk2
|
APN |
18 |
65,483,644 (GRCm39) |
missense |
probably benign |
0.29 |
|
IGL00978:Alpk2
|
APN |
18 |
65,424,605 (GRCm39) |
splice site |
probably benign |
|
|
IGL01093:Alpk2
|
APN |
18 |
65,482,400 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01094:Alpk2
|
APN |
18 |
65,439,673 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01109:Alpk2
|
APN |
18 |
65,440,211 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL01370:Alpk2
|
APN |
18 |
65,483,662 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
IGL01393:Alpk2
|
APN |
18 |
65,440,779 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL01629:Alpk2
|
APN |
18 |
65,433,113 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01872:Alpk2
|
APN |
18 |
65,437,824 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01983:Alpk2
|
APN |
18 |
65,483,753 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02294:Alpk2
|
APN |
18 |
65,439,146 (GRCm39) |
missense |
possibly damaging |
0.45 |
|
IGL02333:Alpk2
|
APN |
18 |
65,482,551 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02493:Alpk2
|
APN |
18 |
65,483,402 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02551:Alpk2
|
APN |
18 |
65,505,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02864:Alpk2
|
APN |
18 |
65,440,670 (GRCm39) |
missense |
probably benign |
0.12 |
|
IGL02901:Alpk2
|
APN |
18 |
65,439,482 (GRCm39) |
missense |
probably benign |
|
|
IGL02954:Alpk2
|
APN |
18 |
65,439,207 (GRCm39) |
missense |
probably benign |
|
|
IGL03257:Alpk2
|
APN |
18 |
65,482,945 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03389:Alpk2
|
APN |
18 |
65,437,937 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
3-1:Alpk2
|
UTSW |
18 |
65,437,959 (GRCm39) |
missense |
probably damaging |
0.99 |
|
PIT4131001:Alpk2
|
UTSW |
18 |
65,439,450 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0098:Alpk2
|
UTSW |
18 |
65,482,982 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0098:Alpk2
|
UTSW |
18 |
65,482,982 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0414:Alpk2
|
UTSW |
18 |
65,439,230 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0546:Alpk2
|
UTSW |
18 |
65,439,788 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0628:Alpk2
|
UTSW |
18 |
65,440,367 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0658:Alpk2
|
UTSW |
18 |
65,482,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0731:Alpk2
|
UTSW |
18 |
65,438,461 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0919:Alpk2
|
UTSW |
18 |
65,440,544 (GRCm39) |
missense |
probably benign |
|
|
R1069:Alpk2
|
UTSW |
18 |
65,438,085 (GRCm39) |
missense |
probably benign |
0.25 |
|
R1186:Alpk2
|
UTSW |
18 |
65,427,412 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1508:Alpk2
|
UTSW |
18 |
65,482,376 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1535:Alpk2
|
UTSW |
18 |
65,483,275 (GRCm39) |
missense |
probably benign |
|
|
R1558:Alpk2
|
UTSW |
18 |
65,483,301 (GRCm39) |
missense |
probably benign |
|
|
R1600:Alpk2
|
UTSW |
18 |
65,511,108 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1664:Alpk2
|
UTSW |
18 |
65,482,944 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1829:Alpk2
|
UTSW |
18 |
65,427,165 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R2110:Alpk2
|
UTSW |
18 |
65,440,151 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2111:Alpk2
|
UTSW |
18 |
65,482,845 (GRCm39) |
missense |
probably benign |
|
|
R2113:Alpk2
|
UTSW |
18 |
65,438,754 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2126:Alpk2
|
UTSW |
18 |
65,483,439 (GRCm39) |
nonsense |
probably null |
|
|
R2198:Alpk2
|
UTSW |
18 |
65,483,255 (GRCm39) |
missense |
probably benign |
0.42 |
|
R2227:Alpk2
|
UTSW |
18 |
65,511,147 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2245:Alpk2
|
UTSW |
18 |
65,438,234 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2282:Alpk2
|
UTSW |
18 |
65,440,697 (GRCm39) |
missense |
probably benign |
|
|
R2421:Alpk2
|
UTSW |
18 |
65,439,687 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2512:Alpk2
|
UTSW |
18 |
65,483,591 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3105:Alpk2
|
UTSW |
18 |
65,483,281 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R3700:Alpk2
|
UTSW |
18 |
65,438,222 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4205:Alpk2
|
UTSW |
18 |
65,438,282 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R4239:Alpk2
|
UTSW |
18 |
65,433,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4353:Alpk2
|
UTSW |
18 |
65,424,523 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R4572:Alpk2
|
UTSW |
18 |
65,414,075 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4584:Alpk2
|
UTSW |
18 |
65,440,035 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4591:Alpk2
|
UTSW |
18 |
65,438,894 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4595:Alpk2
|
UTSW |
18 |
65,422,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4648:Alpk2
|
UTSW |
18 |
65,482,953 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4815:Alpk2
|
UTSW |
18 |
65,483,026 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4828:Alpk2
|
UTSW |
18 |
65,482,184 (GRCm39) |
missense |
probably benign |
|
|
R4910:Alpk2
|
UTSW |
18 |
65,399,357 (GRCm39) |
nonsense |
probably null |
|
|
R5042:Alpk2
|
UTSW |
18 |
65,483,579 (GRCm39) |
nonsense |
probably null |
|
|
R5295:Alpk2
|
UTSW |
18 |
65,438,109 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5375:Alpk2
|
UTSW |
18 |
65,505,809 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5475:Alpk2
|
UTSW |
18 |
65,440,083 (GRCm39) |
missense |
probably benign |
0.16 |
|
R5480:Alpk2
|
UTSW |
18 |
65,482,979 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5486:Alpk2
|
UTSW |
18 |
65,427,425 (GRCm39) |
splice site |
probably null |
|
|
R5503:Alpk2
|
UTSW |
18 |
65,439,312 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5595:Alpk2
|
UTSW |
18 |
65,399,319 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5648:Alpk2
|
UTSW |
18 |
65,482,988 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5714:Alpk2
|
UTSW |
18 |
65,438,532 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R5862:Alpk2
|
UTSW |
18 |
65,440,360 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5894:Alpk2
|
UTSW |
18 |
65,414,143 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5898:Alpk2
|
UTSW |
18 |
65,440,694 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5936:Alpk2
|
UTSW |
18 |
65,483,591 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6142:Alpk2
|
UTSW |
18 |
65,438,456 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6291:Alpk2
|
UTSW |
18 |
65,438,972 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6339:Alpk2
|
UTSW |
18 |
65,482,877 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6407:Alpk2
|
UTSW |
18 |
65,422,809 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6487:Alpk2
|
UTSW |
18 |
65,399,254 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R6667:Alpk2
|
UTSW |
18 |
65,440,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6786:Alpk2
|
UTSW |
18 |
65,439,705 (GRCm39) |
missense |
probably benign |
|
|
R6833:Alpk2
|
UTSW |
18 |
65,439,480 (GRCm39) |
missense |
probably benign |
0.08 |
|
R6984:Alpk2
|
UTSW |
18 |
65,438,749 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6999:Alpk2
|
UTSW |
18 |
65,437,584 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7157:Alpk2
|
UTSW |
18 |
65,399,348 (GRCm39) |
nonsense |
probably null |
|
|
R7167:Alpk2
|
UTSW |
18 |
65,440,049 (GRCm39) |
missense |
probably benign |
0.40 |
|
R7225:Alpk2
|
UTSW |
18 |
65,438,270 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7409:Alpk2
|
UTSW |
18 |
65,440,023 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7533:Alpk2
|
UTSW |
18 |
65,437,674 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7576:Alpk2
|
UTSW |
18 |
65,439,887 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7589:Alpk2
|
UTSW |
18 |
65,433,144 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7598:Alpk2
|
UTSW |
18 |
65,437,637 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7664:Alpk2
|
UTSW |
18 |
65,440,073 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7711:Alpk2
|
UTSW |
18 |
65,439,555 (GRCm39) |
missense |
probably benign |
|
|
R7722:Alpk2
|
UTSW |
18 |
65,483,228 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7783:Alpk2
|
UTSW |
18 |
65,439,325 (GRCm39) |
nonsense |
probably null |
|
|
R7806:Alpk2
|
UTSW |
18 |
65,482,487 (GRCm39) |
missense |
probably benign |
|
|
R7953:Alpk2
|
UTSW |
18 |
65,482,901 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8024:Alpk2
|
UTSW |
18 |
65,438,106 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8043:Alpk2
|
UTSW |
18 |
65,482,901 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8063:Alpk2
|
UTSW |
18 |
65,483,417 (GRCm39) |
missense |
probably benign |
0.15 |
|
R8171:Alpk2
|
UTSW |
18 |
65,439,054 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8280:Alpk2
|
UTSW |
18 |
65,440,274 (GRCm39) |
missense |
probably benign |
|
|
R8383:Alpk2
|
UTSW |
18 |
65,438,469 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8414:Alpk2
|
UTSW |
18 |
65,440,542 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8791:Alpk2
|
UTSW |
18 |
65,438,597 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8872:Alpk2
|
UTSW |
18 |
65,413,977 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9352:Alpk2
|
UTSW |
18 |
65,439,783 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9449:Alpk2
|
UTSW |
18 |
65,424,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9525:Alpk2
|
UTSW |
18 |
65,399,288 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9564:Alpk2
|
UTSW |
18 |
65,439,014 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9710:Alpk2
|
UTSW |
18 |
65,482,646 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0023:Alpk2
|
UTSW |
18 |
65,424,471 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0027:Alpk2
|
UTSW |
18 |
65,440,542 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
X0063:Alpk2
|
UTSW |
18 |
65,440,434 (GRCm39) |
missense |
probably benign |
|
|
X0064:Alpk2
|
UTSW |
18 |
65,482,755 (GRCm39) |
missense |
probably benign |
0.09 |
|
Z1176:Alpk2
|
UTSW |
18 |
65,438,682 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- CACCGACATTTCCTAGAGGTCAGC -3'
(R):5'- CAGACACTGTTCCCGTCTGAAATCC -3'
Sequencing Primer
(F):5'- CCCAAGCTTCATTTGTAATGGGAC -3'
(R):5'- CCCGTCTGAAATCCAGATGTG -3'
|
| Posted On |
2014-05-09 |
Incidental Mutation