Incidental Mutation 'R1677:Anapc1'
| ID |
188154 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Anapc1
|
| Ensembl Gene |
ENSMUSG00000014355 |
| Gene Name |
anaphase promoting complex subunit 1 |
| Synonyms |
Apc1, tsg24, Mcpr, 2610021O03Rik |
| MMRRC Submission |
039713-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1677 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
128452024-128529311 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 128518128 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Proline to Leucine
at position 242
(P242L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000105962
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000014499]
[ENSMUST00000110333]
|
| AlphaFold |
P53995 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000014499
AA Change: P242L
PolyPhen 2
Score 0.024 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000014499
Gene: ENSMUSG00000014355
AA Change: P242L
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ANAPC1
|
150 |
214 |
1.7e-13 |
PFAM |
|
low complexity region
|
323 |
345 |
N/A |
INTRINSIC |
|
low complexity region
|
1404 |
1415 |
N/A |
INTRINSIC |
|
Pfam:PC_rep
|
1467 |
1501 |
8.3e-8 |
PFAM |
|
low complexity region
|
1516 |
1528 |
N/A |
INTRINSIC |
|
low complexity region
|
1924 |
1936 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000110333
AA Change: P242L
PolyPhen 2
Score 0.095 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000105962
Gene: ENSMUSG00000014355
AA Change: P242L
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Apc1
|
149 |
227 |
1.7e-22 |
PFAM |
|
low complexity region
|
323 |
345 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000134485
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.3%
- 20x: 92.6%
|
| Validation Efficiency |
100% (95/95) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 90 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700093K21Rik |
A |
T |
11: 23,467,357 (GRCm39) |
M92K |
probably benign |
Het |
| 4931406C07Rik |
T |
C |
9: 15,212,660 (GRCm39) |
|
probably null |
Het |
| A430005L14Rik |
G |
A |
4: 154,045,357 (GRCm39) |
V129M |
probably damaging |
Het |
| Actg2 |
T |
C |
6: 83,499,801 (GRCm39) |
T150A |
possibly damaging |
Het |
| Actn1 |
A |
T |
12: 80,306,806 (GRCm39) |
D20E |
probably benign |
Het |
| Alcam |
C |
T |
16: 52,091,136 (GRCm39) |
E461K |
probably damaging |
Het |
| Ankrd49 |
A |
T |
9: 14,692,674 (GRCm39) |
D163E |
probably benign |
Het |
| Atp8b5 |
G |
A |
4: 43,372,903 (GRCm39) |
R1149Q |
possibly damaging |
Het |
| Cacnb3 |
G |
T |
15: 98,540,455 (GRCm39) |
V328F |
probably damaging |
Het |
| Camk4 |
T |
C |
18: 33,309,275 (GRCm39) |
I226T |
probably damaging |
Het |
| Ccdc148 |
T |
C |
2: 58,892,176 (GRCm39) |
D172G |
probably damaging |
Het |
| Cdh12 |
A |
G |
15: 21,520,491 (GRCm39) |
I319V |
probably damaging |
Het |
| Cenpc1 |
T |
C |
5: 86,209,857 (GRCm39) |
|
probably benign |
Het |
| Cfap69 |
A |
C |
5: 5,632,457 (GRCm39) |
N15K |
probably damaging |
Het |
| Ckap2l |
A |
C |
2: 129,127,087 (GRCm39) |
S364A |
possibly damaging |
Het |
| Clic6 |
G |
A |
16: 92,324,972 (GRCm39) |
G36R |
probably damaging |
Het |
| Col6a3 |
T |
C |
1: 90,749,583 (GRCm39) |
Y417C |
probably benign |
Het |
| Cstf3 |
T |
A |
2: 104,494,623 (GRCm39) |
|
probably benign |
Het |
| Cyp4f39 |
G |
A |
17: 32,711,304 (GRCm39) |
A484T |
probably benign |
Het |
| Dnah3 |
T |
C |
7: 119,527,963 (GRCm39) |
N3829D |
probably damaging |
Het |
| Dntt |
C |
A |
19: 41,017,923 (GRCm39) |
P16T |
probably benign |
Het |
| Dym |
T |
A |
18: 75,258,583 (GRCm39) |
I447N |
probably damaging |
Het |
| Elmo1 |
T |
C |
13: 20,773,841 (GRCm39) |
V617A |
probably benign |
Het |
| Elovl7 |
G |
A |
13: 108,419,160 (GRCm39) |
G264D |
probably damaging |
Het |
| Epha7 |
T |
A |
4: 28,947,571 (GRCm39) |
Y610* |
probably null |
Het |
| Fn1 |
T |
C |
1: 71,636,814 (GRCm39) |
I178V |
probably benign |
Het |
| Fndc9 |
T |
C |
11: 46,129,152 (GRCm39) |
Y224H |
probably benign |
Het |
| Gad1 |
T |
C |
2: 70,404,521 (GRCm39) |
V137A |
probably damaging |
Het |
| Gapvd1 |
A |
G |
2: 34,590,773 (GRCm39) |
|
probably null |
Het |
| Gbp11 |
C |
T |
5: 105,475,277 (GRCm39) |
C357Y |
probably damaging |
Het |
| Gcc1 |
G |
A |
6: 28,419,163 (GRCm39) |
A390V |
probably benign |
Het |
| Gm6811 |
A |
G |
17: 21,314,185 (GRCm39) |
|
noncoding transcript |
Het |
| Htt |
A |
T |
5: 34,985,918 (GRCm39) |
D1063V |
probably damaging |
Het |
| Igfn1 |
C |
T |
1: 135,898,839 (GRCm39) |
A576T |
probably damaging |
Het |
| Il12rb2 |
T |
C |
6: 67,280,485 (GRCm39) |
Y240C |
probably damaging |
Het |
| Itga3 |
T |
C |
11: 94,946,585 (GRCm39) |
D747G |
probably damaging |
Het |
| Kcnip2 |
A |
C |
19: 45,782,979 (GRCm39) |
D134E |
probably damaging |
Het |
| Kif2b |
C |
A |
11: 91,466,798 (GRCm39) |
R495I |
probably damaging |
Het |
| Lef1 |
T |
C |
3: 130,993,938 (GRCm39) |
|
probably benign |
Het |
| Lias |
C |
T |
5: 65,548,981 (GRCm39) |
R4C |
probably damaging |
Het |
| Lpcat2 |
T |
C |
8: 93,591,560 (GRCm39) |
V68A |
probably benign |
Het |
| Lrrc37 |
A |
T |
11: 103,505,768 (GRCm39) |
S2067T |
probably benign |
Het |
| Lrrc8e |
A |
T |
8: 4,284,190 (GRCm39) |
K138N |
probably damaging |
Het |
| Map4k5 |
G |
A |
12: 69,852,082 (GRCm39) |
H767Y |
probably benign |
Het |
| Mga |
C |
A |
2: 119,791,333 (GRCm39) |
T2406K |
possibly damaging |
Het |
| Mtx1 |
A |
T |
3: 89,116,648 (GRCm39) |
S418T |
probably benign |
Het |
| Myh7 |
C |
T |
14: 55,224,973 (GRCm39) |
M531I |
probably benign |
Het |
| Myorg |
C |
T |
4: 41,497,947 (GRCm39) |
R561H |
probably benign |
Het |
| Ncaph2 |
T |
A |
15: 89,255,427 (GRCm39) |
M555K |
probably damaging |
Het |
| Nckap1 |
C |
T |
2: 80,348,286 (GRCm39) |
S889N |
probably benign |
Het |
| Ncoa6 |
T |
C |
2: 155,244,584 (GRCm39) |
|
probably benign |
Het |
| Nrp2 |
A |
G |
1: 62,822,479 (GRCm39) |
S691G |
probably benign |
Het |
| Odad2 |
T |
C |
18: 7,222,554 (GRCm39) |
T572A |
probably benign |
Het |
| Odf2l |
A |
T |
3: 144,845,543 (GRCm39) |
|
probably null |
Het |
| Or5aq6 |
T |
A |
2: 86,923,081 (GRCm39) |
H220L |
probably benign |
Het |
| Pcdh20 |
A |
G |
14: 88,705,410 (GRCm39) |
V630A |
probably damaging |
Het |
| Pebp4 |
T |
C |
14: 70,285,923 (GRCm39) |
|
probably null |
Het |
| Ppfia3 |
T |
A |
7: 45,006,090 (GRCm39) |
M301L |
probably benign |
Het |
| Ppp1r21 |
C |
A |
17: 88,858,097 (GRCm39) |
Q203K |
probably benign |
Het |
| Prr23a1 |
T |
C |
9: 98,725,406 (GRCm39) |
V256A |
probably benign |
Het |
| Rbfox1 |
A |
G |
16: 7,110,091 (GRCm39) |
R150G |
possibly damaging |
Het |
| Rnps1-ps |
A |
T |
6: 7,982,943 (GRCm39) |
|
noncoding transcript |
Het |
| Robo3 |
T |
C |
9: 37,329,005 (GRCm39) |
R1238G |
possibly damaging |
Het |
| Rp9 |
T |
G |
9: 22,365,097 (GRCm39) |
Q35P |
probably damaging |
Het |
| Rsrc1 |
C |
A |
3: 67,262,808 (GRCm39) |
A254E |
probably damaging |
Het |
| Shtn1 |
T |
A |
19: 58,998,222 (GRCm39) |
K390N |
probably damaging |
Het |
| Sidt2 |
C |
T |
9: 45,864,517 (GRCm39) |
V71I |
probably benign |
Het |
| Sirt7 |
A |
G |
11: 120,515,365 (GRCm39) |
V97A |
possibly damaging |
Het |
| Slc14a2 |
A |
G |
18: 78,206,419 (GRCm39) |
S466P |
probably benign |
Het |
| Slc2a10 |
T |
A |
2: 165,357,361 (GRCm39) |
D340E |
probably benign |
Het |
| Slc36a2 |
A |
C |
11: 55,075,735 (GRCm39) |
N17K |
probably benign |
Het |
| Slc4a10 |
A |
C |
2: 62,155,071 (GRCm39) |
N1086T |
probably benign |
Het |
| Sptb |
T |
C |
12: 76,676,423 (GRCm39) |
D177G |
probably damaging |
Het |
| Srpk2 |
A |
T |
5: 23,730,748 (GRCm39) |
|
probably null |
Het |
| Sucla2 |
T |
G |
14: 73,830,121 (GRCm39) |
V386G |
probably damaging |
Het |
| Susd1 |
G |
T |
4: 59,424,089 (GRCm39) |
N45K |
possibly damaging |
Het |
| Tbxas1 |
T |
C |
6: 38,994,822 (GRCm39) |
|
probably benign |
Het |
| Topors |
C |
T |
4: 40,261,776 (GRCm39) |
E503K |
probably damaging |
Het |
| Trpv5 |
T |
C |
6: 41,634,731 (GRCm39) |
R533G |
probably benign |
Het |
| Tshr |
A |
G |
12: 91,504,115 (GRCm39) |
H351R |
possibly damaging |
Het |
| Ube2f |
G |
A |
1: 91,203,037 (GRCm39) |
V94M |
probably damaging |
Het |
| Ugdh |
A |
G |
5: 65,580,521 (GRCm39) |
S216P |
probably damaging |
Het |
| Unc45b |
T |
A |
11: 82,802,531 (GRCm39) |
|
probably null |
Het |
| Vmn1r226 |
A |
G |
17: 20,908,335 (GRCm39) |
E189G |
probably damaging |
Het |
| Xrcc6 |
T |
G |
15: 81,913,900 (GRCm39) |
D75E |
probably benign |
Het |
| Ypel1 |
A |
G |
16: 16,921,474 (GRCm39) |
L70P |
probably damaging |
Het |
| Zcwpw1 |
A |
T |
5: 137,795,022 (GRCm39) |
R73W |
probably damaging |
Het |
| Zfp219 |
T |
C |
14: 52,246,512 (GRCm39) |
E160G |
probably damaging |
Het |
| Zfp804b |
G |
T |
5: 7,229,533 (GRCm39) |
|
probably benign |
Het |
| Zscan22 |
C |
A |
7: 12,640,730 (GRCm39) |
P325T |
probably damaging |
Het |
|
| Other mutations in Anapc1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00232:Anapc1
|
APN |
2 |
128,487,050 (GRCm39) |
splice site |
probably benign |
|
|
IGL00704:Anapc1
|
APN |
2 |
128,505,904 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL01023:Anapc1
|
APN |
2 |
128,471,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01432:Anapc1
|
APN |
2 |
128,475,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01549:Anapc1
|
APN |
2 |
128,495,090 (GRCm39) |
missense |
probably benign |
|
|
IGL02089:Anapc1
|
APN |
2 |
128,505,853 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02275:Anapc1
|
APN |
2 |
128,501,772 (GRCm39) |
missense |
probably benign |
|
|
IGL02570:Anapc1
|
APN |
2 |
128,487,120 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02597:Anapc1
|
APN |
2 |
128,465,851 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02726:Anapc1
|
APN |
2 |
128,501,705 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL03265:Anapc1
|
APN |
2 |
128,469,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03304:Anapc1
|
APN |
2 |
128,469,033 (GRCm39) |
splice site |
probably benign |
|
|
IGL03327:Anapc1
|
APN |
2 |
128,465,854 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0023:Anapc1
|
UTSW |
2 |
128,520,138 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0027:Anapc1
|
UTSW |
2 |
128,483,431 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R0027:Anapc1
|
UTSW |
2 |
128,483,431 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R0084:Anapc1
|
UTSW |
2 |
128,465,886 (GRCm39) |
splice site |
probably benign |
|
|
R0103:Anapc1
|
UTSW |
2 |
128,522,372 (GRCm39) |
splice site |
probably benign |
|
|
R0103:Anapc1
|
UTSW |
2 |
128,522,372 (GRCm39) |
splice site |
probably benign |
|
|
R0109:Anapc1
|
UTSW |
2 |
128,476,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0109:Anapc1
|
UTSW |
2 |
128,476,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0241:Anapc1
|
UTSW |
2 |
128,470,549 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0241:Anapc1
|
UTSW |
2 |
128,470,549 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0255:Anapc1
|
UTSW |
2 |
128,476,631 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0377:Anapc1
|
UTSW |
2 |
128,483,260 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0467:Anapc1
|
UTSW |
2 |
128,510,963 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0514:Anapc1
|
UTSW |
2 |
128,474,575 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0591:Anapc1
|
UTSW |
2 |
128,461,252 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0919:Anapc1
|
UTSW |
2 |
128,459,651 (GRCm39) |
missense |
probably benign |
|
|
R1175:Anapc1
|
UTSW |
2 |
128,522,108 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1473:Anapc1
|
UTSW |
2 |
128,459,617 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R1547:Anapc1
|
UTSW |
2 |
128,459,476 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1556:Anapc1
|
UTSW |
2 |
128,466,819 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1567:Anapc1
|
UTSW |
2 |
128,459,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1635:Anapc1
|
UTSW |
2 |
128,470,452 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1645:Anapc1
|
UTSW |
2 |
128,500,166 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1854:Anapc1
|
UTSW |
2 |
128,517,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1856:Anapc1
|
UTSW |
2 |
128,501,708 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1959:Anapc1
|
UTSW |
2 |
128,475,335 (GRCm39) |
missense |
probably benign |
0.36 |
|
R1984:Anapc1
|
UTSW |
2 |
128,511,608 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R2034:Anapc1
|
UTSW |
2 |
128,490,378 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2283:Anapc1
|
UTSW |
2 |
128,484,468 (GRCm39) |
missense |
probably benign |
0.23 |
|
R2928:Anapc1
|
UTSW |
2 |
128,522,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3547:Anapc1
|
UTSW |
2 |
128,484,602 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R3904:Anapc1
|
UTSW |
2 |
128,484,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4156:Anapc1
|
UTSW |
2 |
128,469,149 (GRCm39) |
intron |
probably benign |
|
|
R4359:Anapc1
|
UTSW |
2 |
128,465,476 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R4392:Anapc1
|
UTSW |
2 |
128,518,169 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4574:Anapc1
|
UTSW |
2 |
128,469,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4682:Anapc1
|
UTSW |
2 |
128,505,925 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4770:Anapc1
|
UTSW |
2 |
128,527,980 (GRCm39) |
splice site |
probably benign |
|
|
R4824:Anapc1
|
UTSW |
2 |
128,470,610 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R4960:Anapc1
|
UTSW |
2 |
128,526,514 (GRCm39) |
missense |
probably benign |
0.23 |
|
R5016:Anapc1
|
UTSW |
2 |
128,449,095 (GRCm39) |
unclassified |
probably benign |
|
|
R5063:Anapc1
|
UTSW |
2 |
128,471,469 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R5128:Anapc1
|
UTSW |
2 |
128,501,837 (GRCm39) |
missense |
probably benign |
|
|
R5271:Anapc1
|
UTSW |
2 |
128,527,905 (GRCm39) |
nonsense |
probably null |
|
|
R5363:Anapc1
|
UTSW |
2 |
128,492,114 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5469:Anapc1
|
UTSW |
2 |
128,517,621 (GRCm39) |
nonsense |
probably null |
|
|
R5473:Anapc1
|
UTSW |
2 |
128,449,115 (GRCm39) |
unclassified |
probably benign |
|
|
R5559:Anapc1
|
UTSW |
2 |
128,522,354 (GRCm39) |
nonsense |
probably null |
|
|
R5631:Anapc1
|
UTSW |
2 |
128,499,137 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5747:Anapc1
|
UTSW |
2 |
128,466,836 (GRCm39) |
missense |
probably benign |
0.19 |
|
R5840:Anapc1
|
UTSW |
2 |
128,448,957 (GRCm39) |
unclassified |
probably benign |
|
|
R6226:Anapc1
|
UTSW |
2 |
128,492,292 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6526:Anapc1
|
UTSW |
2 |
128,514,055 (GRCm39) |
nonsense |
probably null |
|
|
R6561:Anapc1
|
UTSW |
2 |
128,505,919 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6743:Anapc1
|
UTSW |
2 |
128,526,454 (GRCm39) |
nonsense |
probably null |
|
|
R6799:Anapc1
|
UTSW |
2 |
128,501,657 (GRCm39) |
missense |
probably null |
0.38 |
|
R6887:Anapc1
|
UTSW |
2 |
128,501,688 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R6978:Anapc1
|
UTSW |
2 |
128,511,820 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7011:Anapc1
|
UTSW |
2 |
128,490,601 (GRCm39) |
splice site |
probably null |
|
|
R7041:Anapc1
|
UTSW |
2 |
128,470,576 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7047:Anapc1
|
UTSW |
2 |
128,457,350 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7074:Anapc1
|
UTSW |
2 |
128,520,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7109:Anapc1
|
UTSW |
2 |
128,516,522 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7123:Anapc1
|
UTSW |
2 |
128,454,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7309:Anapc1
|
UTSW |
2 |
128,516,604 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7693:Anapc1
|
UTSW |
2 |
128,483,457 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7839:Anapc1
|
UTSW |
2 |
128,526,528 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7847:Anapc1
|
UTSW |
2 |
128,511,828 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7960:Anapc1
|
UTSW |
2 |
128,516,513 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8061:Anapc1
|
UTSW |
2 |
128,490,408 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8127:Anapc1
|
UTSW |
2 |
128,474,547 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8228:Anapc1
|
UTSW |
2 |
128,461,837 (GRCm39) |
nonsense |
probably null |
|
|
R8402:Anapc1
|
UTSW |
2 |
128,472,148 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8422:Anapc1
|
UTSW |
2 |
128,517,757 (GRCm39) |
missense |
probably benign |
|
|
R8425:Anapc1
|
UTSW |
2 |
128,511,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8469:Anapc1
|
UTSW |
2 |
128,500,264 (GRCm39) |
splice site |
probably null |
|
|
R8553:Anapc1
|
UTSW |
2 |
128,461,833 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8688:Anapc1
|
UTSW |
2 |
128,527,748 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8699:Anapc1
|
UTSW |
2 |
128,483,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8719:Anapc1
|
UTSW |
2 |
128,483,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8775:Anapc1
|
UTSW |
2 |
128,499,093 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8775-TAIL:Anapc1
|
UTSW |
2 |
128,499,093 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8806:Anapc1
|
UTSW |
2 |
128,464,333 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R8973:Anapc1
|
UTSW |
2 |
128,505,952 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8977:Anapc1
|
UTSW |
2 |
128,483,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9000:Anapc1
|
UTSW |
2 |
128,476,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9080:Anapc1
|
UTSW |
2 |
128,464,426 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9203:Anapc1
|
UTSW |
2 |
128,465,422 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R9314:Anapc1
|
UTSW |
2 |
128,464,420 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R9386:Anapc1
|
UTSW |
2 |
128,459,642 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9415:Anapc1
|
UTSW |
2 |
128,476,598 (GRCm39) |
missense |
probably benign |
|
|
R9436:Anapc1
|
UTSW |
2 |
128,518,045 (GRCm39) |
missense |
probably benign |
|
|
R9516:Anapc1
|
UTSW |
2 |
128,517,633 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R9563:Anapc1
|
UTSW |
2 |
128,505,980 (GRCm39) |
nonsense |
probably null |
|
|
R9572:Anapc1
|
UTSW |
2 |
128,505,976 (GRCm39) |
missense |
probably benign |
|
|
R9757:Anapc1
|
UTSW |
2 |
128,517,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9766:Anapc1
|
UTSW |
2 |
128,500,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0066:Anapc1
|
UTSW |
2 |
128,516,621 (GRCm39) |
missense |
probably benign |
0.10 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGCAAGTGTTCAGGGTTCGCTATC -3'
(R):5'- AACACCCTTTGCCTCTGGCTGATG -3'
Sequencing Primer
(F):5'- TATCTGTCATGGGACGCAGC -3'
(R):5'- GTCAGAGTGGAACAGTCATTATGTC -3'
|
| Posted On |
2014-05-09 |
Incidental Mutation