Incidental Mutation 'R1681:Kif1b'
| ID |
188489 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Kif1b
|
| Ensembl Gene |
ENSMUSG00000063077 |
| Gene Name |
kinesin family member 1B |
| Synonyms |
N-3 kinesin, KIF1Bp130, KIF1Bp204, Kif1b beta, Kif1b alpha, D4Mil1e, A530096N05Rik |
| MMRRC Submission |
039717-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1681 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
149260776-149392150 bp(-) (GRCm39) |
| Type of Mutation |
critical splice acceptor site |
| DNA Base Change (assembly) |
T to A
at 149279958 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000055647]
[ENSMUST00000060537]
|
| AlphaFold |
Q60575 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000055647
|
| SMART Domains |
Protein: ENSMUSP00000061472
Gene: ENSMUSG00000063077
| Domain | Start | End | E-Value | Type |
|---|
|
KISc
|
3 |
356 |
5.85e-176 |
SMART |
|
low complexity region
|
389 |
404 |
N/A |
INTRINSIC |
|
FHA
|
509 |
566 |
1.61e-4 |
SMART |
|
coiled coil region
|
626 |
685 |
N/A |
INTRINSIC |
|
Pfam:KIF1B
|
799 |
846 |
9.7e-13 |
PFAM |
|
internal_repeat_1
|
901 |
933 |
7.01e-7 |
PROSPERO |
|
low complexity region
|
1165 |
1179 |
N/A |
INTRINSIC |
|
Pfam:DUF3694
|
1220 |
1368 |
1.1e-46 |
PFAM |
|
low complexity region
|
1444 |
1461 |
N/A |
INTRINSIC |
|
low complexity region
|
1479 |
1507 |
N/A |
INTRINSIC |
|
low complexity region
|
1573 |
1591 |
N/A |
INTRINSIC |
|
PH
|
1656 |
1755 |
1.02e-14 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000060537
|
| SMART Domains |
Protein: ENSMUSP00000056754
Gene: ENSMUSG00000063077
| Domain | Start | End | E-Value | Type |
|---|
|
KISc
|
3 |
362 |
7.61e-175 |
SMART |
|
low complexity region
|
390 |
400 |
N/A |
INTRINSIC |
|
low complexity region
|
432 |
450 |
N/A |
INTRINSIC |
|
FHA
|
555 |
612 |
1.61e-4 |
SMART |
|
coiled coil region
|
672 |
731 |
N/A |
INTRINSIC |
|
Pfam:KIF1B
|
845 |
892 |
7.1e-15 |
PFAM |
|
internal_repeat_1
|
947 |
979 |
4.76e-7 |
PROSPERO |
|
low complexity region
|
1211 |
1225 |
N/A |
INTRINSIC |
|
Pfam:DUF3694
|
1266 |
1413 |
1.1e-40 |
PFAM |
|
low complexity region
|
1490 |
1507 |
N/A |
INTRINSIC |
|
low complexity region
|
1525 |
1553 |
N/A |
INTRINSIC |
|
low complexity region
|
1619 |
1637 |
N/A |
INTRINSIC |
|
PH
|
1702 |
1801 |
1.02e-14 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000139123
|
| SMART Domains |
Protein: ENSMUSP00000120076
Gene: ENSMUSG00000063077
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF3694
|
1 |
92 |
4.4e-23 |
PFAM |
|
low complexity region
|
169 |
186 |
N/A |
INTRINSIC |
|
low complexity region
|
204 |
232 |
N/A |
INTRINSIC |
|
low complexity region
|
298 |
316 |
N/A |
INTRINSIC |
|
PH
|
381 |
480 |
1.02e-14 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000139123
|
| SMART Domains |
Protein: ENSMUSP00000120076
Gene: ENSMUSG00000063077
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF3694
|
1 |
92 |
4.4e-23 |
PFAM |
|
low complexity region
|
169 |
186 |
N/A |
INTRINSIC |
|
low complexity region
|
204 |
232 |
N/A |
INTRINSIC |
|
low complexity region
|
298 |
316 |
N/A |
INTRINSIC |
|
PH
|
381 |
480 |
1.02e-14 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.6%
- 20x: 93.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a motor protein that transports mitochondria and synaptic vesicle precursors. Mutations in this gene cause Charcot-Marie-Tooth disease, type 2A1. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygotes for a targeted null mutation exhibit reduced brain size, elevated pain threshold, and neonatal death from apnea. Heterozygotes exhibit impaired synaptic vesicle precursor transport and progressive muscle weakness. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acaca |
T |
A |
11: 84,117,011 (GRCm39) |
I247N |
probably damaging |
Het |
| Ankle1 |
G |
T |
8: 71,860,262 (GRCm39) |
S260I |
probably benign |
Het |
| Aoc2 |
T |
C |
11: 101,216,018 (GRCm39) |
S34P |
probably benign |
Het |
| Ap1m1 |
A |
C |
8: 73,009,966 (GRCm39) |
I397L |
possibly damaging |
Het |
| Apba1 |
C |
A |
19: 23,913,925 (GRCm39) |
D649E |
probably damaging |
Het |
| Aptx |
C |
T |
4: 40,697,274 (GRCm39) |
V25M |
probably benign |
Het |
| Arhgef18 |
G |
A |
8: 3,489,645 (GRCm39) |
G326R |
probably damaging |
Het |
| Atm |
A |
C |
9: 53,433,455 (GRCm39) |
I265S |
possibly damaging |
Het |
| B3galt4 |
A |
T |
17: 34,170,187 (GRCm39) |
V17E |
probably benign |
Het |
| Bcl7a |
T |
A |
5: 123,494,086 (GRCm39) |
M86K |
possibly damaging |
Het |
| Calhm6 |
A |
G |
10: 34,003,896 (GRCm39) |
F4L |
probably benign |
Het |
| Cela3a |
T |
A |
4: 137,129,995 (GRCm39) |
|
probably null |
Het |
| Cep85 |
T |
A |
4: 133,876,039 (GRCm39) |
K456* |
probably null |
Het |
| Ces1f |
C |
A |
8: 94,002,042 (GRCm39) |
A29S |
probably benign |
Het |
| Chd9 |
A |
T |
8: 91,699,763 (GRCm39) |
I598F |
probably damaging |
Het |
| Cntln |
T |
C |
4: 84,865,872 (GRCm39) |
L176S |
probably damaging |
Het |
| Cntn3 |
A |
T |
6: 102,147,629 (GRCm39) |
N909K |
probably damaging |
Het |
| Cntnap5b |
T |
C |
1: 100,003,832 (GRCm39) |
S271P |
probably damaging |
Het |
| Col6a3 |
T |
A |
1: 90,701,224 (GRCm39) |
H2564L |
unknown |
Het |
| Cyp2b19 |
C |
A |
7: 26,462,765 (GRCm39) |
|
probably null |
Het |
| Dapk1 |
G |
T |
13: 60,866,278 (GRCm39) |
|
probably null |
Het |
| Dnah7b |
T |
A |
1: 46,363,872 (GRCm39) |
Y3497* |
probably null |
Het |
| Duoxa2 |
T |
C |
2: 122,129,643 (GRCm39) |
|
probably null |
Het |
| Eny2 |
T |
C |
15: 44,295,874 (GRCm39) |
W42R |
probably damaging |
Het |
| Epha3 |
A |
G |
16: 63,416,091 (GRCm39) |
V635A |
probably damaging |
Het |
| Fam167b |
G |
C |
4: 129,472,069 (GRCm39) |
Q34E |
probably benign |
Het |
| Fancm |
T |
C |
12: 65,152,430 (GRCm39) |
M962T |
probably benign |
Het |
| Gimap8 |
T |
A |
6: 48,633,345 (GRCm39) |
I388N |
probably benign |
Het |
| Gpaa1 |
A |
G |
15: 76,215,653 (GRCm39) |
T22A |
probably benign |
Het |
| Hoxc11 |
T |
C |
15: 102,863,591 (GRCm39) |
S211P |
possibly damaging |
Het |
| Hsd17b12 |
T |
C |
2: 93,863,906 (GRCm39) |
N312S |
unknown |
Het |
| Idh2 |
T |
G |
7: 79,748,906 (GRCm39) |
E125A |
probably damaging |
Het |
| Igdcc4 |
A |
G |
9: 65,036,077 (GRCm39) |
Y712C |
probably damaging |
Het |
| Kank1 |
T |
C |
19: 25,387,668 (GRCm39) |
V447A |
possibly damaging |
Het |
| Klc4 |
A |
T |
17: 46,947,696 (GRCm39) |
D335E |
probably damaging |
Het |
| Klhl33 |
T |
A |
14: 51,130,534 (GRCm39) |
D320V |
probably benign |
Het |
| Krt73 |
A |
T |
15: 101,710,482 (GRCm39) |
M84K |
possibly damaging |
Het |
| Kti12 |
T |
A |
4: 108,706,055 (GRCm39) |
I323N |
probably damaging |
Het |
| Kynu |
T |
C |
2: 43,569,837 (GRCm39) |
L373P |
probably damaging |
Het |
| Lats1 |
T |
C |
10: 7,581,678 (GRCm39) |
M821T |
probably damaging |
Het |
| Lnx1 |
A |
T |
5: 74,846,071 (GRCm39) |
H126Q |
probably benign |
Het |
| Lonrf2 |
G |
A |
1: 38,852,357 (GRCm39) |
P165S |
probably benign |
Het |
| Lrrc4b |
T |
A |
7: 44,110,601 (GRCm39) |
Y158N |
probably damaging |
Het |
| Lrrc74b |
C |
A |
16: 17,377,617 (GRCm39) |
R87L |
probably damaging |
Het |
| Meig1 |
T |
C |
2: 3,410,311 (GRCm39) |
D63G |
probably damaging |
Het |
| Mrpl38 |
G |
A |
11: 116,029,255 (GRCm39) |
|
probably benign |
Het |
| Mtcl2 |
T |
C |
2: 156,872,450 (GRCm39) |
T966A |
possibly damaging |
Het |
| Naip2 |
C |
T |
13: 100,298,368 (GRCm39) |
G556D |
probably benign |
Het |
| Naip2 |
T |
C |
13: 100,298,362 (GRCm39) |
E558G |
probably benign |
Het |
| Nlrp1a |
T |
A |
11: 71,033,184 (GRCm39) |
E3D |
unknown |
Het |
| Nphs2 |
T |
A |
1: 156,148,468 (GRCm39) |
D110E |
probably damaging |
Het |
| Nxn |
T |
A |
11: 76,163,290 (GRCm39) |
K244N |
probably benign |
Het |
| Oas3 |
A |
T |
5: 120,907,973 (GRCm39) |
F322L |
probably benign |
Het |
| Obscn |
T |
A |
11: 58,994,151 (GRCm39) |
Y1577F |
probably damaging |
Het |
| Or10ag57 |
G |
A |
2: 87,218,964 (GRCm39) |
R305K |
possibly damaging |
Het |
| Or8b47 |
T |
A |
9: 38,435,413 (GRCm39) |
N128K |
probably benign |
Het |
| Or8b50 |
G |
A |
9: 38,518,244 (GRCm39) |
G161D |
probably damaging |
Het |
| Or8b52 |
A |
G |
9: 38,576,616 (GRCm39) |
Y175H |
probably benign |
Het |
| Or8d2 |
T |
C |
9: 38,759,809 (GRCm39) |
M133T |
probably damaging |
Het |
| Panx1 |
T |
C |
9: 14,919,079 (GRCm39) |
D260G |
probably benign |
Het |
| Pcdhb15 |
T |
C |
18: 37,606,866 (GRCm39) |
Y33H |
probably damaging |
Het |
| Pik3ap1 |
C |
A |
19: 41,296,968 (GRCm39) |
V461F |
probably damaging |
Het |
| Plpp3 |
G |
A |
4: 105,066,002 (GRCm39) |
|
probably null |
Het |
| Prtn3 |
A |
T |
10: 79,716,375 (GRCm39) |
T61S |
probably benign |
Het |
| Psen1 |
T |
A |
12: 83,771,394 (GRCm39) |
Y225N |
probably damaging |
Het |
| Rab44 |
T |
A |
17: 29,359,098 (GRCm39) |
S429T |
possibly damaging |
Het |
| Ralgapa1 |
T |
C |
12: 55,809,388 (GRCm39) |
I462M |
probably benign |
Het |
| Rbfox3 |
T |
C |
11: 118,396,495 (GRCm39) |
N105S |
probably damaging |
Het |
| Rbm7 |
A |
C |
9: 48,401,021 (GRCm39) |
Y236D |
possibly damaging |
Het |
| Samhd1 |
T |
C |
2: 156,943,652 (GRCm39) |
T621A |
probably benign |
Het |
| Samt3 |
C |
A |
X: 85,090,256 (GRCm39) |
D49E |
probably benign |
Het |
| Sass6 |
T |
C |
3: 116,397,122 (GRCm39) |
V26A |
possibly damaging |
Het |
| Scn11a |
C |
T |
9: 119,633,478 (GRCm39) |
M418I |
possibly damaging |
Het |
| Scrib |
T |
C |
15: 75,936,416 (GRCm39) |
E480G |
probably damaging |
Het |
| Sec24a |
T |
G |
11: 51,586,016 (GRCm39) |
T1071P |
probably damaging |
Het |
| Siglecg |
A |
C |
7: 43,058,365 (GRCm39) |
E84A |
probably benign |
Het |
| Slc6a17 |
C |
T |
3: 107,381,702 (GRCm39) |
V419I |
probably damaging |
Het |
| Ssr2 |
T |
C |
3: 88,488,349 (GRCm39) |
M75T |
possibly damaging |
Het |
| Tbc1d22b |
A |
G |
17: 29,794,151 (GRCm39) |
T275A |
possibly damaging |
Het |
| Tbx15 |
T |
A |
3: 99,259,140 (GRCm39) |
|
probably null |
Het |
| Tll1 |
A |
C |
8: 64,538,585 (GRCm39) |
L353R |
possibly damaging |
Het |
| Tlr4 |
C |
T |
4: 66,759,342 (GRCm39) |
P712S |
probably damaging |
Het |
| Tmem145 |
T |
A |
7: 25,014,159 (GRCm39) |
F424L |
possibly damaging |
Het |
| Tnrc18 |
T |
C |
5: 142,759,572 (GRCm39) |
K755E |
unknown |
Het |
| Trmt44 |
A |
G |
5: 35,727,321 (GRCm39) |
I298T |
probably benign |
Het |
| Vmn1r69 |
A |
G |
7: 10,314,179 (GRCm39) |
V184A |
probably benign |
Het |
| Zfp84 |
T |
C |
7: 29,476,825 (GRCm39) |
C506R |
probably damaging |
Het |
|
| Other mutations in Kif1b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01311:Kif1b
|
APN |
4 |
149,305,059 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01943:Kif1b
|
APN |
4 |
149,299,362 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02240:Kif1b
|
APN |
4 |
149,330,871 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02414:Kif1b
|
APN |
4 |
149,283,771 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02490:Kif1b
|
APN |
4 |
149,288,665 (GRCm39) |
missense |
probably benign |
|
|
IGL02501:Kif1b
|
APN |
4 |
149,299,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02833:Kif1b
|
APN |
4 |
149,330,821 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02852:Kif1b
|
APN |
4 |
149,375,785 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02900:Kif1b
|
APN |
4 |
149,265,266 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL03287:Kif1b
|
APN |
4 |
149,299,438 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL03412:Kif1b
|
APN |
4 |
149,359,396 (GRCm39) |
missense |
probably benign |
0.00 |
|
PIT4305001:Kif1b
|
UTSW |
4 |
149,305,249 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0005:Kif1b
|
UTSW |
4 |
149,266,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0044:Kif1b
|
UTSW |
4 |
149,348,058 (GRCm39) |
splice site |
probably benign |
|
|
R0044:Kif1b
|
UTSW |
4 |
149,348,058 (GRCm39) |
splice site |
probably benign |
|
|
R0129:Kif1b
|
UTSW |
4 |
149,345,658 (GRCm39) |
missense |
probably benign |
|
|
R0180:Kif1b
|
UTSW |
4 |
149,298,116 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0288:Kif1b
|
UTSW |
4 |
149,283,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0360:Kif1b
|
UTSW |
4 |
149,347,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0383:Kif1b
|
UTSW |
4 |
149,286,969 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0398:Kif1b
|
UTSW |
4 |
149,288,688 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0403:Kif1b
|
UTSW |
4 |
149,266,424 (GRCm39) |
nonsense |
probably null |
|
|
R0445:Kif1b
|
UTSW |
4 |
149,272,466 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1466:Kif1b
|
UTSW |
4 |
149,307,709 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1466:Kif1b
|
UTSW |
4 |
149,307,709 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1728:Kif1b
|
UTSW |
4 |
149,272,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1840:Kif1b
|
UTSW |
4 |
149,272,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1874:Kif1b
|
UTSW |
4 |
149,272,089 (GRCm39) |
missense |
probably benign |
|
|
R1915:Kif1b
|
UTSW |
4 |
149,351,673 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2106:Kif1b
|
UTSW |
4 |
149,272,097 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2124:Kif1b
|
UTSW |
4 |
149,306,753 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2126:Kif1b
|
UTSW |
4 |
149,272,097 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2127:Kif1b
|
UTSW |
4 |
149,272,097 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2128:Kif1b
|
UTSW |
4 |
149,272,097 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2129:Kif1b
|
UTSW |
4 |
149,272,097 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2146:Kif1b
|
UTSW |
4 |
149,268,766 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2255:Kif1b
|
UTSW |
4 |
149,359,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2392:Kif1b
|
UTSW |
4 |
149,305,077 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2883:Kif1b
|
UTSW |
4 |
149,322,105 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R2981:Kif1b
|
UTSW |
4 |
149,304,998 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3038:Kif1b
|
UTSW |
4 |
149,297,790 (GRCm39) |
missense |
probably benign |
0.02 |
|
R3616:Kif1b
|
UTSW |
4 |
149,346,740 (GRCm39) |
splice site |
probably benign |
|
|
R3935:Kif1b
|
UTSW |
4 |
149,321,617 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4347:Kif1b
|
UTSW |
4 |
149,331,691 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4423:Kif1b
|
UTSW |
4 |
149,298,562 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4637:Kif1b
|
UTSW |
4 |
149,283,768 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4745:Kif1b
|
UTSW |
4 |
149,322,339 (GRCm39) |
nonsense |
probably null |
|
|
R4807:Kif1b
|
UTSW |
4 |
149,332,378 (GRCm39) |
intron |
probably benign |
|
|
R5618:Kif1b
|
UTSW |
4 |
149,354,346 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5644:Kif1b
|
UTSW |
4 |
149,322,939 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5683:Kif1b
|
UTSW |
4 |
149,306,718 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5696:Kif1b
|
UTSW |
4 |
149,358,306 (GRCm39) |
splice site |
probably null |
|
|
R6022:Kif1b
|
UTSW |
4 |
149,282,989 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6048:Kif1b
|
UTSW |
4 |
149,348,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6137:Kif1b
|
UTSW |
4 |
149,322,883 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R6139:Kif1b
|
UTSW |
4 |
149,321,989 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6171:Kif1b
|
UTSW |
4 |
149,342,505 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6250:Kif1b
|
UTSW |
4 |
149,298,100 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6423:Kif1b
|
UTSW |
4 |
149,277,053 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6424:Kif1b
|
UTSW |
4 |
149,277,053 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6425:Kif1b
|
UTSW |
4 |
149,277,053 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6443:Kif1b
|
UTSW |
4 |
149,277,053 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6460:Kif1b
|
UTSW |
4 |
149,277,053 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6462:Kif1b
|
UTSW |
4 |
149,277,053 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6463:Kif1b
|
UTSW |
4 |
149,277,053 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6469:Kif1b
|
UTSW |
4 |
149,277,053 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6470:Kif1b
|
UTSW |
4 |
149,277,053 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6471:Kif1b
|
UTSW |
4 |
149,277,053 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6472:Kif1b
|
UTSW |
4 |
149,277,053 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6504:Kif1b
|
UTSW |
4 |
149,277,053 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6536:Kif1b
|
UTSW |
4 |
149,277,053 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6537:Kif1b
|
UTSW |
4 |
149,277,053 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6668:Kif1b
|
UTSW |
4 |
149,297,864 (GRCm39) |
missense |
probably benign |
0.09 |
|
R6698:Kif1b
|
UTSW |
4 |
149,359,413 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7065:Kif1b
|
UTSW |
4 |
149,286,982 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7222:Kif1b
|
UTSW |
4 |
149,309,614 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7342:Kif1b
|
UTSW |
4 |
149,298,547 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7720:Kif1b
|
UTSW |
4 |
149,266,812 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7744:Kif1b
|
UTSW |
4 |
149,321,532 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7797:Kif1b
|
UTSW |
4 |
149,321,844 (GRCm39) |
missense |
probably benign |
|
|
R7829:Kif1b
|
UTSW |
4 |
149,305,447 (GRCm39) |
splice site |
probably null |
|
|
R7869:Kif1b
|
UTSW |
4 |
149,268,833 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7878:Kif1b
|
UTSW |
4 |
149,299,454 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7980:Kif1b
|
UTSW |
4 |
149,354,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8047:Kif1b
|
UTSW |
4 |
149,299,379 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8237:Kif1b
|
UTSW |
4 |
149,275,642 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8243:Kif1b
|
UTSW |
4 |
149,288,724 (GRCm39) |
missense |
probably benign |
|
|
R8252:Kif1b
|
UTSW |
4 |
149,358,262 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8342:Kif1b
|
UTSW |
4 |
149,306,805 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8460:Kif1b
|
UTSW |
4 |
149,272,077 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8462:Kif1b
|
UTSW |
4 |
149,266,797 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8496:Kif1b
|
UTSW |
4 |
149,277,068 (GRCm39) |
nonsense |
probably null |
|
|
R8687:Kif1b
|
UTSW |
4 |
149,345,620 (GRCm39) |
nonsense |
probably null |
|
|
R8694:Kif1b
|
UTSW |
4 |
149,305,024 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8842:Kif1b
|
UTSW |
4 |
149,338,196 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8883:Kif1b
|
UTSW |
4 |
149,361,342 (GRCm39) |
missense |
probably benign |
|
|
R8971:Kif1b
|
UTSW |
4 |
149,332,273 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8994:Kif1b
|
UTSW |
4 |
149,279,939 (GRCm39) |
missense |
|
|
|
R9002:Kif1b
|
UTSW |
4 |
149,275,712 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9227:Kif1b
|
UTSW |
4 |
149,322,357 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9231:Kif1b
|
UTSW |
4 |
149,275,652 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9450:Kif1b
|
UTSW |
4 |
149,322,467 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9478:Kif1b
|
UTSW |
4 |
149,345,616 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9571:Kif1b
|
UTSW |
4 |
149,305,098 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9644:Kif1b
|
UTSW |
4 |
149,375,836 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF008:Kif1b
|
UTSW |
4 |
149,336,195 (GRCm39) |
splice site |
probably null |
|
|
X0009:Kif1b
|
UTSW |
4 |
149,331,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0062:Kif1b
|
UTSW |
4 |
149,359,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Kif1b
|
UTSW |
4 |
149,350,755 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
| Predicted Primers |
|
| Posted On |
2014-05-09 |
Incidental Mutation