Incidental Mutation 'R1656:Clip1'
| ID |
189091 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Clip1
|
| Ensembl Gene |
ENSMUSG00000049550 |
| Gene Name |
CAP-GLY domain containing linker protein 1 |
| Synonyms |
Rsn, CLIP-170, 4631429H07Rik, restin, Clip 170, 1110007I12Rik, Clip50, cytoplasmic linker protein 50 |
| MMRRC Submission |
039692-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1656 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
123715857-123822527 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 123768466 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Glycine
at position 757
(V757G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000031382
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000031382]
[ENSMUST00000063905]
[ENSMUST00000111561]
[ENSMUST00000111564]
[ENSMUST00000111566]
[ENSMUST00000149410]
|
| AlphaFold |
Q922J3 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000031382
AA Change: V757G
PolyPhen 2
Score 0.612 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000031382
Gene: ENSMUSG00000049550
AA Change: V757G
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2.28e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2.28e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
451 |
N/A |
INTRINSIC |
|
coiled coil region
|
474 |
535 |
N/A |
INTRINSIC |
|
coiled coil region
|
581 |
620 |
N/A |
INTRINSIC |
|
coiled coil region
|
652 |
1352 |
N/A |
INTRINSIC |
|
low complexity region
|
1362 |
1373 |
N/A |
INTRINSIC |
|
Pfam:CLIP1_ZNF
|
1375 |
1392 |
5.8e-9 |
PFAM |
|
ZnF_C2HC
|
1417 |
1433 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000063905
|
| SMART Domains |
Protein: ENSMUSP00000068241
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
3.3e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
3.3e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
524 |
N/A |
INTRINSIC |
|
coiled coil region
|
570 |
609 |
N/A |
INTRINSIC |
|
coiled coil region
|
641 |
1075 |
N/A |
INTRINSIC |
|
coiled coil region
|
1115 |
1235 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1256 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1300 |
1316 |
1.45e0 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000111561
AA Change: V746G
PolyPhen 2
Score 0.514 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000107186
Gene: ENSMUSG00000049550
AA Change: V746G
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
1.93e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
1.93e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
524 |
N/A |
INTRINSIC |
|
coiled coil region
|
570 |
609 |
N/A |
INTRINSIC |
|
coiled coil region
|
641 |
1341 |
N/A |
INTRINSIC |
|
low complexity region
|
1351 |
1362 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1406 |
1422 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111564
|
| SMART Domains |
Protein: ENSMUSP00000107190
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2.5e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2.5e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
489 |
N/A |
INTRINSIC |
|
coiled coil region
|
535 |
574 |
N/A |
INTRINSIC |
|
coiled coil region
|
606 |
1230 |
N/A |
INTRINSIC |
|
low complexity region
|
1240 |
1251 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1295 |
1311 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111566
AA Change: V711G
PolyPhen 2
Score 0.320 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000107192
Gene: ENSMUSG00000049550
AA Change: V711G
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
489 |
N/A |
INTRINSIC |
|
coiled coil region
|
535 |
574 |
N/A |
INTRINSIC |
|
coiled coil region
|
606 |
1306 |
N/A |
INTRINSIC |
|
low complexity region
|
1316 |
1327 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1371 |
1387 |
1.45e0 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000122603
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000137363
|
| SMART Domains |
Protein: ENSMUSP00000121425
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
CAP_GLY
|
2 |
31 |
2.59e0 |
SMART |
|
low complexity region
|
39 |
57 |
N/A |
INTRINSIC |
|
low complexity region
|
58 |
84 |
N/A |
INTRINSIC |
|
coiled coil region
|
101 |
276 |
N/A |
INTRINSIC |
|
coiled coil region
|
322 |
361 |
N/A |
INTRINSIC |
|
coiled coil region
|
393 |
980 |
N/A |
INTRINSIC |
|
low complexity region
|
991 |
1002 |
N/A |
INTRINSIC |
|
Pfam:CLIP1_ZNF
|
1004 |
1021 |
4.2e-9 |
PFAM |
|
ZnF_C2HC
|
1046 |
1062 |
1.45e0 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000199018
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000149410
|
| SMART Domains |
Protein: ENSMUSP00000115965
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
26 |
32 |
N/A |
INTRINSIC |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
334 |
458 |
N/A |
INTRINSIC |
|
coiled coil region
|
504 |
543 |
N/A |
INTRINSIC |
|
coiled coil region
|
575 |
827 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000144121
|
| SMART Domains |
Protein: ENSMUSP00000119641
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
CAP_GLY
|
37 |
102 |
1.05e-31 |
SMART |
|
| Meta Mutation Damage Score |
0.0614 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.6%
- 20x: 93.3%
|
| Validation Efficiency |
96% (79/82) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
PHENOTYPE: Mice homozygous for a targeted allele display reduced male fertility and teratozoospermia. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 77 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700024G13Rik |
A |
T |
14: 32,099,901 (GRCm39) |
I42N |
possibly damaging |
Het |
| Adarb2 |
T |
A |
13: 8,253,287 (GRCm39) |
S11T |
unknown |
Het |
| Adgrg1 |
C |
T |
8: 95,738,438 (GRCm39) |
Q644* |
probably null |
Het |
| Akr1c18 |
T |
G |
13: 4,195,252 (GRCm39) |
I69L |
probably benign |
Het |
| Anxa9 |
C |
T |
3: 95,207,884 (GRCm39) |
V219I |
probably benign |
Het |
| Aqp9 |
T |
C |
9: 71,045,385 (GRCm39) |
T101A |
probably benign |
Het |
| Arhgef1 |
C |
T |
7: 24,613,057 (GRCm39) |
R251W |
probably damaging |
Het |
| Arl13b |
T |
A |
16: 62,627,007 (GRCm39) |
E231D |
possibly damaging |
Het |
| Atosa |
C |
T |
9: 74,916,241 (GRCm39) |
A280V |
probably benign |
Het |
| Bcl2l11 |
C |
T |
2: 128,000,176 (GRCm39) |
A173V |
probably benign |
Het |
| Ccni |
A |
T |
5: 93,335,933 (GRCm39) |
|
probably null |
Het |
| Cdh18 |
A |
G |
15: 23,474,485 (GRCm39) |
E785G |
probably benign |
Het |
| Cdk4 |
A |
G |
10: 126,900,849 (GRCm39) |
Y167C |
probably benign |
Het |
| Ctsc |
T |
C |
7: 87,930,616 (GRCm39) |
V65A |
possibly damaging |
Het |
| Cuedc2 |
G |
A |
19: 46,320,427 (GRCm39) |
S48L |
probably damaging |
Het |
| Cyp39a1 |
T |
A |
17: 43,978,510 (GRCm39) |
M4K |
possibly damaging |
Het |
| Dgcr8 |
T |
C |
16: 18,074,577 (GRCm39) |
S733G |
probably benign |
Het |
| Dnhd1 |
T |
C |
7: 105,363,488 (GRCm39) |
S4017P |
probably damaging |
Het |
| Ehbp1 |
A |
G |
11: 22,096,694 (GRCm39) |
I255T |
probably benign |
Het |
| Fam83e |
T |
C |
7: 45,371,687 (GRCm39) |
V28A |
probably benign |
Het |
| Fanci |
A |
G |
7: 79,054,936 (GRCm39) |
|
probably benign |
Het |
| Fat1 |
C |
T |
8: 45,478,567 (GRCm39) |
Q2538* |
probably null |
Het |
| Fshr |
A |
G |
17: 89,508,009 (GRCm39) |
F11S |
unknown |
Het |
| Gab1 |
G |
T |
8: 81,515,388 (GRCm39) |
P310Q |
probably damaging |
Het |
| Galnt18 |
A |
G |
7: 111,215,699 (GRCm39) |
|
probably benign |
Het |
| Gm28042 |
C |
A |
2: 119,869,370 (GRCm39) |
P355Q |
probably damaging |
Het |
| H2-DMa |
A |
G |
17: 34,357,116 (GRCm39) |
T205A |
possibly damaging |
Het |
| Hnf4g |
A |
T |
3: 3,718,011 (GRCm39) |
D420V |
probably benign |
Het |
| Ift70b |
T |
C |
2: 75,767,760 (GRCm39) |
K331R |
probably benign |
Het |
| Il1b |
A |
G |
2: 129,207,989 (GRCm39) |
V164A |
probably damaging |
Het |
| Irf4 |
C |
A |
13: 30,941,485 (GRCm39) |
H279Q |
probably benign |
Het |
| Loxhd1 |
A |
G |
18: 77,409,364 (GRCm39) |
T203A |
possibly damaging |
Het |
| Lsamp |
C |
T |
16: 41,775,682 (GRCm39) |
P178S |
probably damaging |
Het |
| Mcm6 |
T |
C |
1: 128,277,155 (GRCm39) |
S223G |
possibly damaging |
Het |
| Misp |
G |
T |
10: 79,661,777 (GRCm39) |
V65L |
possibly damaging |
Het |
| Mov10 |
A |
G |
3: 104,706,912 (GRCm39) |
V666A |
probably benign |
Het |
| Mycbp2 |
A |
T |
14: 103,485,194 (GRCm39) |
D1102E |
probably damaging |
Het |
| Myef2 |
G |
T |
2: 124,939,860 (GRCm39) |
|
probably null |
Het |
| Myo1e |
T |
A |
9: 70,303,216 (GRCm39) |
I1079N |
probably damaging |
Het |
| Nisch |
G |
T |
14: 30,899,228 (GRCm39) |
|
probably benign |
Het |
| Obox7 |
T |
C |
7: 14,399,346 (GRCm39) |
S191P |
probably benign |
Het |
| Or11h7 |
T |
C |
14: 50,891,465 (GRCm39) |
V257A |
probably benign |
Het |
| Or13p10 |
A |
G |
4: 118,523,385 (GRCm39) |
I224V |
probably damaging |
Het |
| Or14c40 |
C |
T |
7: 86,313,331 (GRCm39) |
L154F |
probably benign |
Het |
| Or1j11 |
G |
A |
2: 36,311,658 (GRCm39) |
V83M |
probably benign |
Het |
| Or5w14 |
A |
T |
2: 87,541,422 (GRCm39) |
V276D |
possibly damaging |
Het |
| Or7d9 |
A |
G |
9: 20,197,873 (GRCm39) |
R301G |
probably damaging |
Het |
| Phf1 |
T |
C |
17: 27,156,333 (GRCm39) |
S492P |
possibly damaging |
Het |
| Phyh |
A |
T |
2: 4,943,164 (GRCm39) |
N337I |
probably damaging |
Het |
| Poteg |
A |
T |
8: 27,985,060 (GRCm39) |
|
probably benign |
Het |
| Prag1 |
G |
T |
8: 36,571,500 (GRCm39) |
K694N |
probably damaging |
Het |
| Proser2 |
C |
T |
2: 6,107,870 (GRCm39) |
E49K |
probably damaging |
Het |
| Pskh1 |
T |
C |
8: 106,656,389 (GRCm39) |
V355A |
possibly damaging |
Het |
| Psmc2 |
T |
C |
5: 22,004,549 (GRCm39) |
V182A |
possibly damaging |
Het |
| Rbfox1 |
A |
G |
16: 7,124,333 (GRCm39) |
|
probably benign |
Het |
| Slc26a7 |
A |
T |
4: 14,621,221 (GRCm39) |
I55K |
possibly damaging |
Het |
| Slc5a8 |
G |
A |
10: 88,761,648 (GRCm39) |
|
probably null |
Het |
| Slitrk3 |
T |
C |
3: 72,957,672 (GRCm39) |
R367G |
probably damaging |
Het |
| Snrnp40 |
C |
G |
4: 130,271,836 (GRCm39) |
|
probably null |
Het |
| Spata31 |
A |
G |
13: 65,068,953 (GRCm39) |
E367G |
probably benign |
Het |
| Srrm3 |
A |
T |
5: 135,863,892 (GRCm39) |
|
probably null |
Het |
| Ssmem1 |
T |
C |
6: 30,517,507 (GRCm39) |
S6P |
probably damaging |
Het |
| Swap70 |
A |
G |
7: 109,821,034 (GRCm39) |
D6G |
probably benign |
Het |
| Syt1 |
T |
C |
10: 108,419,776 (GRCm39) |
E295G |
probably damaging |
Het |
| Tap2 |
A |
T |
17: 34,424,927 (GRCm39) |
I192F |
possibly damaging |
Het |
| Tgoln1 |
C |
T |
6: 72,591,068 (GRCm39) |
R348H |
probably damaging |
Het |
| Tln2 |
C |
T |
9: 67,134,389 (GRCm39) |
V1373I |
possibly damaging |
Het |
| Tmc2 |
A |
G |
2: 130,089,854 (GRCm39) |
D613G |
possibly damaging |
Het |
| Tmem62 |
T |
A |
2: 120,837,483 (GRCm39) |
Y597N |
probably benign |
Het |
| Trhr2 |
T |
A |
8: 123,084,185 (GRCm39) |
T272S |
probably damaging |
Het |
| Vmn2r92 |
T |
C |
17: 18,372,198 (GRCm39) |
S3P |
probably benign |
Het |
| Wdfy3 |
A |
T |
5: 102,089,313 (GRCm39) |
I627N |
probably damaging |
Het |
| Zfhx4 |
T |
C |
3: 5,478,076 (GRCm39) |
S3564P |
probably damaging |
Het |
| Zfp467 |
T |
G |
6: 48,416,013 (GRCm39) |
E213A |
possibly damaging |
Het |
| Zfp746 |
T |
G |
6: 48,041,411 (GRCm39) |
K437N |
probably damaging |
Het |
| Zfp853 |
A |
G |
5: 143,274,840 (GRCm39) |
|
probably benign |
Het |
| Zranb1 |
T |
A |
7: 132,551,496 (GRCm39) |
V49D |
probably benign |
Het |
|
| Other mutations in Clip1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00159:Clip1
|
APN |
5 |
123,741,717 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01067:Clip1
|
APN |
5 |
123,768,867 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01524:Clip1
|
APN |
5 |
123,717,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01632:Clip1
|
APN |
5 |
123,755,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01798:Clip1
|
APN |
5 |
123,721,612 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01874:Clip1
|
APN |
5 |
123,741,729 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
IGL01908:Clip1
|
APN |
5 |
123,761,270 (GRCm39) |
splice site |
probably benign |
|
|
IGL02120:Clip1
|
APN |
5 |
123,785,946 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02309:Clip1
|
APN |
5 |
123,755,763 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02555:Clip1
|
APN |
5 |
123,759,857 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03027:Clip1
|
APN |
5 |
123,759,919 (GRCm39) |
missense |
probably benign |
0.43 |
|
IGL03336:Clip1
|
APN |
5 |
123,791,633 (GRCm39) |
nonsense |
probably null |
|
|
IGL03365:Clip1
|
APN |
5 |
123,721,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02802:Clip1
|
UTSW |
5 |
123,769,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4812001:Clip1
|
UTSW |
5 |
123,768,738 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0254:Clip1
|
UTSW |
5 |
123,755,395 (GRCm39) |
splice site |
probably benign |
|
|
R0401:Clip1
|
UTSW |
5 |
123,791,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0530:Clip1
|
UTSW |
5 |
123,778,594 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0744:Clip1
|
UTSW |
5 |
123,768,784 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0833:Clip1
|
UTSW |
5 |
123,768,784 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1116:Clip1
|
UTSW |
5 |
123,717,554 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1182:Clip1
|
UTSW |
5 |
123,785,928 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1700:Clip1
|
UTSW |
5 |
123,768,433 (GRCm39) |
missense |
probably benign |
|
|
R1889:Clip1
|
UTSW |
5 |
123,791,559 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1975:Clip1
|
UTSW |
5 |
123,761,281 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2406:Clip1
|
UTSW |
5 |
123,741,723 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3545:Clip1
|
UTSW |
5 |
123,769,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3547:Clip1
|
UTSW |
5 |
123,769,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3548:Clip1
|
UTSW |
5 |
123,769,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3911:Clip1
|
UTSW |
5 |
123,728,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3944:Clip1
|
UTSW |
5 |
123,755,892 (GRCm39) |
unclassified |
probably benign |
|
|
R4660:Clip1
|
UTSW |
5 |
123,717,437 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4784:Clip1
|
UTSW |
5 |
123,717,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4785:Clip1
|
UTSW |
5 |
123,717,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4824:Clip1
|
UTSW |
5 |
123,769,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4831:Clip1
|
UTSW |
5 |
123,721,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4951:Clip1
|
UTSW |
5 |
123,768,408 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4960:Clip1
|
UTSW |
5 |
123,792,066 (GRCm39) |
nonsense |
probably null |
|
|
R5014:Clip1
|
UTSW |
5 |
123,755,793 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5116:Clip1
|
UTSW |
5 |
123,768,770 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5212:Clip1
|
UTSW |
5 |
123,768,744 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5238:Clip1
|
UTSW |
5 |
123,785,946 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5318:Clip1
|
UTSW |
5 |
123,751,147 (GRCm39) |
unclassified |
probably benign |
|
|
R5372:Clip1
|
UTSW |
5 |
123,768,303 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5701:Clip1
|
UTSW |
5 |
123,751,366 (GRCm39) |
unclassified |
probably benign |
|
|
R5734:Clip1
|
UTSW |
5 |
123,753,217 (GRCm39) |
unclassified |
probably benign |
|
|
R5757:Clip1
|
UTSW |
5 |
123,765,460 (GRCm39) |
missense |
probably benign |
0.21 |
|
R6024:Clip1
|
UTSW |
5 |
123,753,152 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6160:Clip1
|
UTSW |
5 |
123,751,604 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6177:Clip1
|
UTSW |
5 |
123,751,897 (GRCm39) |
unclassified |
probably benign |
|
|
R6183:Clip1
|
UTSW |
5 |
123,780,667 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6377:Clip1
|
UTSW |
5 |
123,741,717 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R6436:Clip1
|
UTSW |
5 |
123,779,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6471:Clip1
|
UTSW |
5 |
123,778,612 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6766:Clip1
|
UTSW |
5 |
123,752,827 (GRCm39) |
unclassified |
probably benign |
|
|
R7015:Clip1
|
UTSW |
5 |
123,751,675 (GRCm39) |
unclassified |
probably benign |
|
|
R7094:Clip1
|
UTSW |
5 |
123,761,333 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7143:Clip1
|
UTSW |
5 |
123,791,673 (GRCm39) |
missense |
probably benign |
|
|
R7222:Clip1
|
UTSW |
5 |
123,749,904 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7233:Clip1
|
UTSW |
5 |
123,749,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7238:Clip1
|
UTSW |
5 |
123,751,328 (GRCm39) |
missense |
|
|
|
R7249:Clip1
|
UTSW |
5 |
123,741,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7283:Clip1
|
UTSW |
5 |
123,751,857 (GRCm39) |
missense |
|
|
|
R7295:Clip1
|
UTSW |
5 |
123,765,419 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7447:Clip1
|
UTSW |
5 |
123,791,696 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7458:Clip1
|
UTSW |
5 |
123,778,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7483:Clip1
|
UTSW |
5 |
123,755,447 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7516:Clip1
|
UTSW |
5 |
123,721,448 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7619:Clip1
|
UTSW |
5 |
123,752,342 (GRCm39) |
missense |
|
|
|
R7831:Clip1
|
UTSW |
5 |
123,751,342 (GRCm39) |
missense |
|
|
|
R7897:Clip1
|
UTSW |
5 |
123,760,861 (GRCm39) |
missense |
probably benign |
|
|
R8155:Clip1
|
UTSW |
5 |
123,751,699 (GRCm39) |
missense |
|
|
|
R8157:Clip1
|
UTSW |
5 |
123,768,782 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8232:Clip1
|
UTSW |
5 |
123,785,981 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8396:Clip1
|
UTSW |
5 |
123,780,627 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8446:Clip1
|
UTSW |
5 |
123,794,008 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8486:Clip1
|
UTSW |
5 |
123,752,770 (GRCm39) |
unclassified |
probably benign |
|
|
R8511:Clip1
|
UTSW |
5 |
123,791,969 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8731:Clip1
|
UTSW |
5 |
123,752,756 (GRCm39) |
missense |
|
|
|
R8889:Clip1
|
UTSW |
5 |
123,717,565 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8892:Clip1
|
UTSW |
5 |
123,717,565 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9058:Clip1
|
UTSW |
5 |
123,752,645 (GRCm39) |
missense |
|
|
|
R9106:Clip1
|
UTSW |
5 |
123,753,223 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9212:Clip1
|
UTSW |
5 |
123,721,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9217:Clip1
|
UTSW |
5 |
123,717,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9223:Clip1
|
UTSW |
5 |
123,784,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9325:Clip1
|
UTSW |
5 |
123,751,186 (GRCm39) |
missense |
|
|
|
R9752:Clip1
|
UTSW |
5 |
123,760,009 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Clip1
|
UTSW |
5 |
123,755,413 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTGCTCTGCTCTCCTCGGAAGAAG -3'
(R):5'- ACCATGCAGGCCAAGCTGATGAAG -3'
Sequencing Primer
(F):5'- AGCTCACGTTAGATCAGGC -3'
(R):5'- GCCAAGCTGATGAAGATCATTAAAG -3'
|
| Posted On |
2014-05-09 |
Incidental Mutation