Incidental Mutation 'R1686:Iqgap3'
| ID |
189321 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Iqgap3
|
| Ensembl Gene |
ENSMUSG00000028068 |
| Gene Name |
IQ motif containing GTPase activating protein 3 |
| Synonyms |
|
| MMRRC Submission |
039719-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.342)
|
| Stock # |
R1686 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
87989309-88028355 bp(+) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
T to A
at 88015663 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000142013
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000071812]
[ENSMUST00000194440]
[ENSMUST00000195465]
|
| AlphaFold |
F8VQ29 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000071812
|
| SMART Domains |
Protein: ENSMUSP00000071715
Gene: ENSMUSG00000028068
| Domain | Start | End | E-Value | Type |
|---|
|
CH
|
36 |
145 |
1.72e-14 |
SMART |
|
internal_repeat_2
|
197 |
249 |
1.75e-5 |
PROSPERO |
|
internal_repeat_1
|
209 |
418 |
1.31e-14 |
PROSPERO |
|
low complexity region
|
419 |
438 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
446 |
651 |
1.31e-14 |
PROSPERO |
|
internal_repeat_2
|
600 |
652 |
1.75e-5 |
PROSPERO |
|
IQ
|
730 |
752 |
1.18e1 |
SMART |
|
IQ
|
760 |
782 |
3.76e-6 |
SMART |
|
IQ
|
790 |
812 |
3.08e-2 |
SMART |
|
IQ
|
820 |
842 |
1.72e0 |
SMART |
|
RasGAP
|
977 |
1330 |
1.74e-57 |
SMART |
|
Blast:RasGAP
|
1338 |
1422 |
1e-9 |
BLAST |
|
Pfam:RasGAP_C
|
1434 |
1555 |
2e-36 |
PFAM |
|
low complexity region
|
1591 |
1602 |
N/A |
INTRINSIC |
|
low complexity region
|
1615 |
1630 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000194440
|
| SMART Domains |
Protein: ENSMUSP00000142035
Gene: ENSMUSG00000028068
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:RasGAP
|
1 |
67 |
3e-30 |
BLAST |
|
RasGAP
|
79 |
432 |
1e-59 |
SMART |
|
Blast:RasGAP
|
440 |
524 |
5e-10 |
BLAST |
|
Pfam:RasGAP_C
|
535 |
660 |
5.7e-30 |
PFAM |
|
low complexity region
|
693 |
704 |
N/A |
INTRINSIC |
|
low complexity region
|
717 |
732 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000194772
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195465
|
| SMART Domains |
Protein: ENSMUSP00000142013
Gene: ENSMUSG00000028068
| Domain | Start | End | E-Value | Type |
|---|
|
CH
|
36 |
145 |
8.5e-17 |
SMART |
|
internal_repeat_1
|
209 |
379 |
1.33e-7 |
PROSPERO |
|
low complexity region
|
419 |
438 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
446 |
612 |
1.33e-7 |
PROSPERO |
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.4%
- 20x: 92.9%
|
| Validation Efficiency |
100% (85/85) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700017N19Rik |
G |
A |
10: 100,448,722 (GRCm39) |
V400I |
probably damaging |
Het |
| Abcb1b |
A |
G |
5: 8,848,782 (GRCm39) |
N14S |
probably damaging |
Het |
| Adamts14 |
A |
G |
10: 61,034,439 (GRCm39) |
Y1150H |
probably benign |
Het |
| Adgrg3 |
A |
G |
8: 95,759,997 (GRCm39) |
N72S |
probably benign |
Het |
| Akain1 |
T |
A |
17: 69,746,527 (GRCm39) |
F3I |
possibly damaging |
Het |
| Akr1c21 |
T |
C |
13: 4,627,452 (GRCm39) |
L182P |
probably damaging |
Het |
| Arhgap21 |
A |
T |
2: 20,886,659 (GRCm39) |
Y12N |
probably damaging |
Het |
| Aup1 |
A |
T |
6: 83,032,226 (GRCm39) |
H131L |
probably damaging |
Het |
| Bag6 |
A |
G |
17: 35,363,928 (GRCm39) |
T812A |
possibly damaging |
Het |
| Bmp2k |
A |
G |
5: 97,211,392 (GRCm39) |
Y520C |
unknown |
Het |
| Calm4 |
T |
G |
13: 3,888,302 (GRCm39) |
V136G |
probably damaging |
Het |
| Catsper2 |
A |
G |
2: 121,230,523 (GRCm39) |
|
probably null |
Het |
| Cc2d2a |
A |
G |
5: 43,896,713 (GRCm39) |
T1537A |
possibly damaging |
Het |
| Cntn2 |
A |
T |
1: 132,454,049 (GRCm39) |
V319D |
possibly damaging |
Het |
| Cux1 |
G |
A |
5: 136,304,235 (GRCm39) |
R1314* |
probably null |
Het |
| Cxcl12 |
A |
G |
6: 117,150,508 (GRCm39) |
I79V |
probably damaging |
Het |
| Cyp2j6 |
T |
C |
4: 96,412,014 (GRCm39) |
D418G |
probably benign |
Het |
| Ddx28 |
G |
C |
8: 106,737,190 (GRCm39) |
D289E |
probably damaging |
Het |
| Fabp3 |
C |
T |
4: 130,206,180 (GRCm39) |
T57I |
probably benign |
Het |
| Fam135a |
A |
C |
1: 24,068,887 (GRCm39) |
S448A |
probably benign |
Het |
| Fbxo33 |
G |
T |
12: 59,251,626 (GRCm39) |
N30K |
possibly damaging |
Het |
| Fgf12 |
A |
C |
16: 28,217,093 (GRCm39) |
Y21D |
probably damaging |
Het |
| Galntl5 |
C |
T |
5: 25,415,432 (GRCm39) |
S288L |
probably benign |
Het |
| Gart |
G |
T |
16: 91,422,237 (GRCm39) |
A760D |
probably damaging |
Het |
| Gba2 |
A |
T |
4: 43,573,869 (GRCm39) |
|
probably benign |
Het |
| Gm10518 |
C |
A |
1: 179,631,357 (GRCm39) |
S139* |
probably null |
Het |
| Gm4781 |
A |
T |
10: 100,232,837 (GRCm39) |
|
noncoding transcript |
Het |
| Gm9790 |
A |
G |
3: 85,823,156 (GRCm39) |
|
noncoding transcript |
Het |
| Gmps |
G |
A |
3: 63,893,075 (GRCm39) |
G127R |
probably damaging |
Het |
| Golim4 |
A |
T |
3: 75,802,443 (GRCm39) |
V283E |
probably benign |
Het |
| Gprc5a |
A |
T |
6: 135,055,918 (GRCm39) |
I122F |
possibly damaging |
Het |
| Gzmc |
T |
C |
14: 56,471,341 (GRCm39) |
K67E |
probably benign |
Het |
| Hapln3 |
C |
A |
7: 78,771,638 (GRCm39) |
V84L |
probably benign |
Het |
| Hif3a |
T |
A |
7: 16,778,789 (GRCm39) |
N377Y |
possibly damaging |
Het |
| Ifi211 |
G |
A |
1: 173,726,969 (GRCm39) |
H392Y |
probably damaging |
Het |
| Itga10 |
T |
A |
3: 96,559,141 (GRCm39) |
F410Y |
probably damaging |
Het |
| Jup |
T |
C |
11: 100,263,260 (GRCm39) |
Y705C |
probably damaging |
Het |
| Khsrp |
C |
T |
17: 57,332,597 (GRCm39) |
A228T |
probably benign |
Het |
| Lmntd2 |
C |
T |
7: 140,790,998 (GRCm39) |
G445D |
probably damaging |
Het |
| Lyst |
T |
C |
13: 13,809,290 (GRCm39) |
V320A |
possibly damaging |
Het |
| Magel2 |
T |
A |
7: 62,027,988 (GRCm39) |
H297Q |
possibly damaging |
Het |
| Mbd6 |
T |
C |
10: 127,123,286 (GRCm39) |
E33G |
probably damaging |
Het |
| Mob3b |
A |
G |
4: 34,985,910 (GRCm39) |
|
probably benign |
Het |
| Mroh2a |
T |
C |
1: 88,162,334 (GRCm39) |
|
probably null |
Het |
| Mroh2a |
C |
T |
1: 88,158,402 (GRCm39) |
R150* |
probably null |
Het |
| Mymk |
A |
T |
2: 26,952,346 (GRCm39) |
W174R |
probably damaging |
Het |
| Nckap1 |
C |
T |
2: 80,348,286 (GRCm39) |
S889N |
probably benign |
Het |
| Nipal3 |
T |
C |
4: 135,174,599 (GRCm39) |
Y384C |
possibly damaging |
Het |
| Nt5c3b |
A |
G |
11: 100,330,920 (GRCm39) |
|
probably benign |
Het |
| Obox6 |
T |
A |
7: 15,567,750 (GRCm39) |
L232F |
probably damaging |
Het |
| Obscn |
A |
C |
11: 58,997,113 (GRCm39) |
|
probably benign |
Het |
| Or7g12 |
T |
C |
9: 18,899,839 (GRCm39) |
L185P |
probably damaging |
Het |
| Phkb |
A |
G |
8: 86,748,278 (GRCm39) |
I706V |
probably benign |
Het |
| Plcb2 |
A |
G |
2: 118,546,168 (GRCm39) |
|
probably benign |
Het |
| Plek2 |
T |
C |
12: 78,941,184 (GRCm39) |
D216G |
probably damaging |
Het |
| Plxnb2 |
T |
C |
15: 89,046,665 (GRCm39) |
Y855C |
probably damaging |
Het |
| Prkcz |
T |
C |
4: 155,355,713 (GRCm39) |
T227A |
probably damaging |
Het |
| Psma7 |
A |
T |
2: 179,679,215 (GRCm39) |
D184E |
probably benign |
Het |
| Rai14 |
T |
A |
15: 10,592,282 (GRCm39) |
L204F |
probably damaging |
Het |
| Ralgapa2 |
A |
G |
2: 146,199,920 (GRCm39) |
V1208A |
probably benign |
Het |
| Rapgef6 |
A |
G |
11: 54,582,458 (GRCm39) |
R67G |
possibly damaging |
Het |
| Ryr2 |
C |
T |
13: 11,618,665 (GRCm39) |
|
probably benign |
Het |
| Satb1 |
T |
C |
17: 52,047,027 (GRCm39) |
S763G |
probably benign |
Het |
| Sdk1 |
A |
T |
5: 142,020,292 (GRCm39) |
H690L |
probably benign |
Het |
| Sfrp5 |
A |
C |
19: 42,190,143 (GRCm39) |
V103G |
possibly damaging |
Het |
| Six6 |
A |
G |
12: 72,988,451 (GRCm39) |
E208G |
probably benign |
Het |
| Sspo |
A |
T |
6: 48,437,334 (GRCm39) |
H1364L |
probably benign |
Het |
| Stard9 |
A |
T |
2: 120,529,973 (GRCm39) |
T2077S |
probably benign |
Het |
| Tacr3 |
T |
C |
3: 134,535,254 (GRCm39) |
L74P |
probably damaging |
Het |
| Tep1 |
T |
C |
14: 51,074,245 (GRCm39) |
E1880G |
probably benign |
Het |
| Tgfb3 |
A |
T |
12: 86,116,517 (GRCm39) |
|
probably benign |
Het |
| Thap7 |
G |
A |
16: 17,346,576 (GRCm39) |
P136S |
probably damaging |
Het |
| Thoc2l |
T |
A |
5: 104,667,789 (GRCm39) |
Y770* |
probably null |
Het |
| Tmc2 |
T |
C |
2: 130,098,036 (GRCm39) |
V717A |
possibly damaging |
Het |
| Usp43 |
T |
A |
11: 67,778,593 (GRCm39) |
S446C |
probably damaging |
Het |
| Vwa3a |
C |
T |
7: 120,379,371 (GRCm39) |
S492L |
probably damaging |
Het |
| Wdhd1 |
T |
A |
14: 47,493,672 (GRCm39) |
N16I |
probably damaging |
Het |
| Wdr95 |
A |
T |
5: 149,516,566 (GRCm39) |
D327V |
probably damaging |
Het |
| Zfp128 |
T |
G |
7: 12,624,563 (GRCm39) |
Y310* |
probably null |
Het |
|
| Other mutations in Iqgap3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01016:Iqgap3
|
APN |
3 |
88,014,867 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01062:Iqgap3
|
APN |
3 |
88,017,429 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01517:Iqgap3
|
APN |
3 |
88,016,703 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL01530:Iqgap3
|
APN |
3 |
88,019,610 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL01658:Iqgap3
|
APN |
3 |
88,023,278 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02027:Iqgap3
|
APN |
3 |
87,994,649 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL02352:Iqgap3
|
APN |
3 |
88,009,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02359:Iqgap3
|
APN |
3 |
88,009,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02522:Iqgap3
|
APN |
3 |
88,015,705 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02717:Iqgap3
|
APN |
3 |
88,005,666 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02971:Iqgap3
|
APN |
3 |
87,997,611 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL03079:Iqgap3
|
APN |
3 |
88,020,477 (GRCm39) |
missense |
probably benign |
|
|
IGL03240:Iqgap3
|
APN |
3 |
88,022,281 (GRCm39) |
missense |
probably benign |
0.00 |
|
adjutant
|
UTSW |
3 |
88,008,834 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
Booster
|
UTSW |
3 |
88,020,435 (GRCm39) |
missense |
probably damaging |
0.99 |
|
peso_ligero
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R0048:Iqgap3
|
UTSW |
3 |
88,023,256 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0048:Iqgap3
|
UTSW |
3 |
88,023,256 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0285:Iqgap3
|
UTSW |
3 |
88,004,297 (GRCm39) |
missense |
probably benign |
0.11 |
|
R0442:Iqgap3
|
UTSW |
3 |
88,023,266 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0490:Iqgap3
|
UTSW |
3 |
88,021,363 (GRCm39) |
splice site |
probably benign |
|
|
R0569:Iqgap3
|
UTSW |
3 |
87,998,032 (GRCm39) |
splice site |
probably benign |
|
|
R0747:Iqgap3
|
UTSW |
3 |
88,014,810 (GRCm39) |
splice site |
probably benign |
|
|
R0843:Iqgap3
|
UTSW |
3 |
88,015,738 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1260:Iqgap3
|
UTSW |
3 |
88,021,330 (GRCm39) |
missense |
probably benign |
|
|
R1465:Iqgap3
|
UTSW |
3 |
87,994,616 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1465:Iqgap3
|
UTSW |
3 |
87,994,616 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1544:Iqgap3
|
UTSW |
3 |
88,006,200 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1662:Iqgap3
|
UTSW |
3 |
88,005,708 (GRCm39) |
missense |
probably benign |
0.33 |
|
R1748:Iqgap3
|
UTSW |
3 |
88,021,287 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1836:Iqgap3
|
UTSW |
3 |
88,015,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1972:Iqgap3
|
UTSW |
3 |
87,991,235 (GRCm39) |
splice site |
probably null |
|
|
R1973:Iqgap3
|
UTSW |
3 |
87,991,235 (GRCm39) |
splice site |
probably null |
|
|
R2051:Iqgap3
|
UTSW |
3 |
88,027,474 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2314:Iqgap3
|
UTSW |
3 |
88,023,338 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2352:Iqgap3
|
UTSW |
3 |
88,011,815 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2857:Iqgap3
|
UTSW |
3 |
88,014,903 (GRCm39) |
nonsense |
probably null |
|
|
R2859:Iqgap3
|
UTSW |
3 |
88,014,903 (GRCm39) |
nonsense |
probably null |
|
|
R3435:Iqgap3
|
UTSW |
3 |
88,001,911 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3522:Iqgap3
|
UTSW |
3 |
87,998,089 (GRCm39) |
missense |
probably null |
0.90 |
|
R4281:Iqgap3
|
UTSW |
3 |
88,006,167 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4283:Iqgap3
|
UTSW |
3 |
88,006,167 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4397:Iqgap3
|
UTSW |
3 |
88,011,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4414:Iqgap3
|
UTSW |
3 |
88,004,293 (GRCm39) |
missense |
probably benign |
|
|
R4660:Iqgap3
|
UTSW |
3 |
88,027,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4872:Iqgap3
|
UTSW |
3 |
88,020,435 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4883:Iqgap3
|
UTSW |
3 |
88,014,842 (GRCm39) |
missense |
probably benign |
|
|
R4915:Iqgap3
|
UTSW |
3 |
88,008,834 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5050:Iqgap3
|
UTSW |
3 |
87,997,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5130:Iqgap3
|
UTSW |
3 |
88,016,161 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5151:Iqgap3
|
UTSW |
3 |
88,025,067 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R5645:Iqgap3
|
UTSW |
3 |
88,025,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5706:Iqgap3
|
UTSW |
3 |
88,023,215 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5748:Iqgap3
|
UTSW |
3 |
88,016,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5880:Iqgap3
|
UTSW |
3 |
88,024,509 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5982:Iqgap3
|
UTSW |
3 |
87,998,899 (GRCm39) |
nonsense |
probably null |
|
|
R6006:Iqgap3
|
UTSW |
3 |
87,998,854 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6026:Iqgap3
|
UTSW |
3 |
87,997,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6188:Iqgap3
|
UTSW |
3 |
88,006,200 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6211:Iqgap3
|
UTSW |
3 |
87,998,822 (GRCm39) |
missense |
probably benign |
|
|
R6291:Iqgap3
|
UTSW |
3 |
87,997,037 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6344:Iqgap3
|
UTSW |
3 |
87,989,401 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6854:Iqgap3
|
UTSW |
3 |
88,004,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6875:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R6877:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R6958:Iqgap3
|
UTSW |
3 |
88,020,673 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7008:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R7050:Iqgap3
|
UTSW |
3 |
88,006,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7144:Iqgap3
|
UTSW |
3 |
88,024,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7170:Iqgap3
|
UTSW |
3 |
88,009,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7288:Iqgap3
|
UTSW |
3 |
88,016,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7952:Iqgap3
|
UTSW |
3 |
88,005,677 (GRCm39) |
missense |
probably benign |
|
|
R8008:Iqgap3
|
UTSW |
3 |
88,016,770 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8049:Iqgap3
|
UTSW |
3 |
88,011,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8176:Iqgap3
|
UTSW |
3 |
88,001,957 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8190:Iqgap3
|
UTSW |
3 |
87,998,086 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8772:Iqgap3
|
UTSW |
3 |
87,997,144 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8878:Iqgap3
|
UTSW |
3 |
88,020,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8893:Iqgap3
|
UTSW |
3 |
87,997,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9072:Iqgap3
|
UTSW |
3 |
88,016,773 (GRCm39) |
missense |
|
|
|
R9072:Iqgap3
|
UTSW |
3 |
87,998,883 (GRCm39) |
missense |
probably benign |
|
|
R9073:Iqgap3
|
UTSW |
3 |
88,016,773 (GRCm39) |
missense |
|
|
|
R9337:Iqgap3
|
UTSW |
3 |
88,023,425 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9489:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9492:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9593:Iqgap3
|
UTSW |
3 |
88,011,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9655:Iqgap3
|
UTSW |
3 |
88,016,728 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9708:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9709:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9752:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9753:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9765:Iqgap3
|
UTSW |
3 |
88,017,361 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R9771:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9772:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Iqgap3
|
UTSW |
3 |
87,996,278 (GRCm39) |
critical splice donor site |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TCTTCCCTGGCAGAATGCAGAGAC -3'
(R):5'- TGTGTGCTGAGCAAGCACTCAC -3'
Sequencing Primer
(F):5'- AACAGGCTGATGCTGCTG -3'
(R):5'- TCACCACCGTGCTACCATC -3'
|
| Posted On |
2014-05-14 |
Incidental Mutation