Mutagenetix > Incidental Mutation

Incidental Mutation 'R1722:Tenm2'

191565

Institutional Source

Beutler Lab

Gene Symbol

Tenm2

Ensembl Gene

ENSMUSG00000049336

Gene Name

teneurin transmembrane protein 2

Synonyms

D3Bwg1534e, Odz2, 9330187F13Rik, Ten-m2, 2610040L17Rik

MMRRC Submission

039754-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.558) question?

Stock #

R1722 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

35897483-37126791 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to C at 35898930 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Aspartic acid at position 2743 (Y2743D)

Ref Sequence

ENSEMBL: ENSMUSP00000129951 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000057207] [ENSMUST00000102801] [ENSMUST00000163524]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000057207
AA Change: Y2744D

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000052014
Gene: ENSMUSG00000049336
AA Change: Y2744D

Domain	Start	End	E-Value	Type
Pfam:Ten_N	10	374	4.9e-177	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	738	766	9.63e0	SMART
EGF	769	797	1.25e1	SMART
EGF	800	832	1.4e0	SMART
low complexity region	1459	1475	N/A	INTRINSIC
low complexity region	2219	2230	N/A	INTRINSIC
Pfam:Tox-GHH	2681	2758	1.4e-34	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000102801
AA Change: Y2743D

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000099865
Gene: ENSMUSG00000049336
AA Change: Y2743D

Domain	Start	End	E-Value	Type
Pfam:Ten_N	9	374	2e-186	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	737	765	9.63e0	SMART
EGF	768	796	1.25e1	SMART
EGF	799	831	1.4e0	SMART
low complexity region	1458	1474	N/A	INTRINSIC
low complexity region	2218	2229	N/A	INTRINSIC
Pfam:Tox-GHH	2679	2757	2e-34	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000163524
AA Change: Y2743D

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000129951
Gene: ENSMUSG00000049336
AA Change: Y2743D

Domain	Start	End	E-Value	Type
Pfam:Ten_N	9	374	2e-186	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	737	765	9.63e0	SMART
EGF	768	796	1.25e1	SMART
EGF	799	831	1.4e0	SMART
low complexity region	1458	1474	N/A	INTRINSIC
low complexity region	2218	2229	N/A	INTRINSIC
Pfam:Tox-GHH	2679	2757	2e-34	PFAM

Coding Region Coverage

1x: 99.2%
3x: 98.5%
10x: 96.9%
20x: 94.3%

Validation Efficiency

MGI Phenotype

PHENOTYPE: Mice homozygous for a null allele show abnormalities in the laterality and mapping of ipsilateral retinal projections that lead to loss of ipsilateral drive, defects in binocular vision, and impaired performance on a visual discrimination task. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 60 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4931422A03Rik	A	T	2: 103,824,273 (GRCm39)		probably null	Het
Adss1	A	T	12: 112,602,915 (GRCm39)	I346F	possibly damaging	Het
Ahnak	T	A	19: 8,988,019 (GRCm39)	L3101H	probably damaging	Het
Aldh3b3	A	G	19: 4,014,871 (GRCm39)	I123V	possibly damaging	Het
Angptl1	C	T	1: 156,684,655 (GRCm39)	P275S	possibly damaging	Het
Apoa5	C	T	9: 46,181,847 (GRCm39)	Q308*	probably null	Het
Arhgef12	T	C	9: 42,932,013 (GRCm39)	*106W	probably null	Het
Atp2c1	A	G	9: 105,316,599 (GRCm39)	Y485H	probably benign	Het
Atp6v1b1	C	T	6: 83,720,074 (GRCm39)	T3I	possibly damaging	Het
Btbd7	A	T	12: 102,778,913 (GRCm39)	I451N	possibly damaging	Het
Clasp1	T	G	1: 118,518,194 (GRCm39)	L1080R	probably damaging	Het
Clec4f	A	G	6: 83,623,915 (GRCm39)	V408A	probably benign	Het
Clint1	T	A	11: 45,797,233 (GRCm39)	M438K	possibly damaging	Het
Cuzd1	A	T	7: 130,913,373 (GRCm39)	Y415N	probably damaging	Het
Ddias	A	G	7: 92,509,250 (GRCm39)	F222L	possibly damaging	Het
Efcab7	A	T	4: 99,757,815 (GRCm39)	T321S	probably benign	Het
Elp3	A	T	14: 65,788,846 (GRCm39)	D393E	probably benign	Het
Fbn2	T	C	18: 58,181,124 (GRCm39)		probably null	Het
Fcgr3	T	C	1: 170,881,688 (GRCm39)	R146G	possibly damaging	Het
Fkrp	G	A	7: 16,544,719 (GRCm39)	A381V	probably benign	Het
Gatad2b	T	G	3: 90,262,986 (GRCm39)	I476S	probably damaging	Het
Gm1527	C	T	3: 28,975,783 (GRCm39)	H557Y	probably benign	Het
Gm2431	A	T	7: 141,811,599 (GRCm39)	C102S	unknown	Het
Hoxd13	A	G	2: 74,500,389 (GRCm39)	N310S	probably benign	Het
Il9	T	A	13: 56,627,208 (GRCm39)	T135S	probably benign	Het
Ints4	A	C	7: 97,162,786 (GRCm39)	N476T	probably benign	Het
Kcnq4	A	C	4: 120,559,624 (GRCm39)	D525E	probably benign	Het
Kncn	A	T	4: 115,743,096 (GRCm39)	Y57F	probably damaging	Het
Lpl	TGG	TG	8: 69,349,254 (GRCm39)		probably null	Het
Lrrfip2	A	G	9: 111,028,829 (GRCm39)	T351A	probably damaging	Het
Madd	T	C	2: 90,997,982 (GRCm39)	E682G	probably benign	Het
Marchf7	A	C	2: 60,064,526 (GRCm39)	R267S	probably damaging	Het
Mmp16	T	A	4: 18,051,767 (GRCm39)	L252Q	probably damaging	Het
Mri1	A	T	8: 84,980,554 (GRCm39)	V296D	possibly damaging	Het
Myo3a	A	G	2: 22,404,638 (GRCm39)	T665A	probably benign	Het
N4bp2	T	C	5: 65,964,225 (GRCm39)	V758A	probably benign	Het
Nbea	T	C	3: 55,573,116 (GRCm39)	D2489G	probably damaging	Het
Neb	T	C	2: 52,146,757 (GRCm39)	T2836A	probably damaging	Het
Nedd4l	T	A	18: 65,291,010 (GRCm39)	V203E	probably damaging	Het
Nkpd1	C	A	7: 19,257,846 (GRCm39)	Q392K	possibly damaging	Het
Nploc4	G	T	11: 120,273,395 (GRCm39)	A576E	probably benign	Het
Nxph1	T	A	6: 9,247,516 (GRCm39)	N162K	probably damaging	Het
Or3a1	T	C	11: 74,225,271 (GRCm39)	Y262C	probably damaging	Het
Or7c70	T	A	10: 78,682,805 (GRCm39)	T315S	probably benign	Het
Pabpc2	T	G	18: 39,908,169 (GRCm39)	I478S	probably benign	Het
Pde7b	G	T	10: 20,311,990 (GRCm39)	H190Q	probably damaging	Het
Plekha2	A	T	8: 25,532,976 (GRCm39)	S332T	probably benign	Het
Rapgef6	TG	TGG	11: 54,437,223 (GRCm39)		probably null	Het
Rasl11a	A	T	5: 146,782,052 (GRCm39)	H9L	probably benign	Het
Rer1	A	T	4: 155,159,458 (GRCm39)	F177I	probably damaging	Het
Rinl	T	C	7: 28,491,669 (GRCm39)	L74P	probably damaging	Het
Rsf1	CG	CGACGGCGGTG	7: 97,229,115 (GRCm39)		probably benign	Het
Rttn	T	C	18: 88,991,655 (GRCm39)	V78A	probably benign	Het
Skint5	A	T	4: 113,703,508 (GRCm39)		probably null	Het
Tmem101	T	C	11: 102,045,519 (GRCm39)	Y110C	probably damaging	Het
Trim9	T	C	12: 70,295,148 (GRCm39)	N658S	probably benign	Het
Ucp1	A	T	8: 84,017,317 (GRCm39)	T36S	probably benign	Het
Vmn2r43	A	G	7: 8,258,067 (GRCm39)	I382T	probably damaging	Het
Zfp142	C	T	1: 74,608,935 (GRCm39)	R1620Q	probably damaging	Het
Zfp386	T	C	12: 116,023,526 (GRCm39)	S380P	probably damaging	Het

Other mutations in Tenm2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00161:Tenm2	APN	11	36,097,726 (GRCm39)	splice site	probably benign
IGL00834:Tenm2	APN	11	35,915,085 (GRCm39)	missense	probably damaging	1.00
IGL00911:Tenm2	APN	11	35,899,560 (GRCm39)	nonsense	probably null
IGL00937:Tenm2	APN	11	35,915,450 (GRCm39)	missense	probably damaging	1.00
IGL01154:Tenm2	APN	11	35,932,371 (GRCm39)	missense	probably damaging	1.00
IGL01313:Tenm2	APN	11	35,915,075 (GRCm39)	missense	probably damaging	0.98
IGL01346:Tenm2	APN	11	35,918,232 (GRCm39)	nonsense	probably null
IGL01539:Tenm2	APN	11	35,997,654 (GRCm39)	missense	possibly damaging	0.89
IGL01629:Tenm2	APN	11	36,755,711 (GRCm39)	missense	probably damaging	0.98
IGL01780:Tenm2	APN	11	35,937,768 (GRCm39)	missense	probably benign
IGL01821:Tenm2	APN	11	35,914,710 (GRCm39)	missense	probably damaging	0.98
IGL01988:Tenm2	APN	11	35,918,078 (GRCm39)	missense	probably damaging	1.00
IGL02002:Tenm2	APN	11	36,097,922 (GRCm39)	missense	probably benign
IGL02449:Tenm2	APN	11	35,914,449 (GRCm39)	missense	probably damaging	0.99
IGL02505:Tenm2	APN	11	35,942,743 (GRCm39)	nonsense	probably null
IGL02649:Tenm2	APN	11	36,097,912 (GRCm39)	missense	possibly damaging	0.85
IGL02688:Tenm2	APN	11	35,959,285 (GRCm39)	missense	probably benign	0.05
IGL02801:Tenm2	APN	11	35,937,857 (GRCm39)	nonsense	probably null
IGL02928:Tenm2	APN	11	35,917,997 (GRCm39)	missense	possibly damaging	0.69
IGL02940:Tenm2	APN	11	35,932,471 (GRCm39)	missense	probably damaging	1.00
IGL03202:Tenm2	APN	11	35,915,375 (GRCm39)	missense	probably damaging	1.00
IGL03213:Tenm2	APN	11	35,914,157 (GRCm39)	missense	probably benign	0.05
IGL03276:Tenm2	APN	11	35,963,603 (GRCm39)	missense	possibly damaging	0.95
IGL03296:Tenm2	APN	11	35,942,852 (GRCm39)	splice site	probably null
IGL03381:Tenm2	APN	11	35,959,238 (GRCm39)	missense	probably benign	0.01
IGL03398:Tenm2	APN	11	35,915,370 (GRCm39)	missense	probably damaging	1.00
browser	UTSW	11	35,937,592 (GRCm39)	critical splice donor site	probably null
mosaic	UTSW	11	35,954,602 (GRCm39)	critical splice donor site	probably null
IGL02799:Tenm2	UTSW	11	36,164,235 (GRCm39)	missense	probably damaging	1.00
PIT4260001:Tenm2	UTSW	11	36,054,557 (GRCm39)	missense	probably damaging	1.00
PIT4382001:Tenm2	UTSW	11	35,954,729 (GRCm39)	missense	probably damaging	0.99
R0004:Tenm2	UTSW	11	35,914,184 (GRCm39)	missense	probably damaging	1.00
R0420:Tenm2	UTSW	11	36,097,951 (GRCm39)	splice site	probably benign
R0537:Tenm2	UTSW	11	36,054,557 (GRCm39)	missense	probably damaging	1.00
R0599:Tenm2	UTSW	11	35,915,607 (GRCm39)	missense	possibly damaging	0.93
R0636:Tenm2	UTSW	11	36,834,803 (GRCm39)	missense	probably damaging	1.00
R0693:Tenm2	UTSW	11	35,915,636 (GRCm39)	missense	probably damaging	1.00
R0991:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R0992:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1167:Tenm2	UTSW	11	36,755,511 (GRCm39)	missense	probably benign	0.30
R1177:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1178:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1179:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1180:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1181:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1193:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1194:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1259:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1265:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1267:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1268:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1269:Tenm2	UTSW	11	35,899,185 (GRCm39)	missense	possibly damaging	0.64
R1270:Tenm2	UTSW	11	35,932,486 (GRCm39)	missense	probably damaging	1.00
R1272:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1273:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1311:Tenm2	UTSW	11	35,959,421 (GRCm39)	splice site	probably benign
R1374:Tenm2	UTSW	11	35,899,281 (GRCm39)	missense	probably benign	0.00
R1542:Tenm2	UTSW	11	36,191,047 (GRCm39)	missense	probably damaging	0.99
R1573:Tenm2	UTSW	11	35,937,896 (GRCm39)	missense	probably damaging	1.00
R1579:Tenm2	UTSW	11	35,997,610 (GRCm39)	missense	probably damaging	1.00
R1697:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1756:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1793:Tenm2	UTSW	11	35,914,209 (GRCm39)	missense	probably damaging	0.99
R1950:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1954:Tenm2	UTSW	11	35,938,374 (GRCm39)	missense	possibly damaging	0.87
R2025:Tenm2	UTSW	11	35,938,091 (GRCm39)	nonsense	probably null
R2117:Tenm2	UTSW	11	35,915,681 (GRCm39)	missense	probably damaging	1.00
R2244:Tenm2	UTSW	11	36,755,689 (GRCm39)	missense	probably damaging	0.98
R2298:Tenm2	UTSW	11	35,937,604 (GRCm39)	missense	possibly damaging	0.62
R2432:Tenm2	UTSW	11	35,918,018 (GRCm39)	missense	probably damaging	1.00
R3014:Tenm2	UTSW	11	35,914,800 (GRCm39)	missense	probably damaging	1.00
R3115:Tenm2	UTSW	11	35,914,193 (GRCm39)	missense	probably damaging	1.00
R3684:Tenm2	UTSW	11	35,942,644 (GRCm39)	missense	probably benign	0.00
R3685:Tenm2	UTSW	11	35,942,644 (GRCm39)	missense	probably benign	0.00
R3705:Tenm2	UTSW	11	35,959,153 (GRCm39)	missense	probably damaging	0.97
R3820:Tenm2	UTSW	11	35,915,147 (GRCm39)	missense	probably damaging	0.98
R3821:Tenm2	UTSW	11	35,915,147 (GRCm39)	missense	probably damaging	0.98
R3822:Tenm2	UTSW	11	35,915,147 (GRCm39)	missense	probably damaging	0.98
R3844:Tenm2	UTSW	11	35,938,365 (GRCm39)	missense	probably damaging	0.98
R3878:Tenm2	UTSW	11	36,030,401 (GRCm39)	critical splice donor site	probably null
R4019:Tenm2	UTSW	11	35,937,901 (GRCm39)	missense	probably benign	0.04
R4062:Tenm2	UTSW	11	35,899,482 (GRCm39)	missense	probably damaging	1.00
R4367:Tenm2	UTSW	11	35,918,225 (GRCm39)	missense	probably benign
R4395:Tenm2	UTSW	11	35,915,451 (GRCm39)	missense	probably benign	0.23
R4508:Tenm2	UTSW	11	35,899,172 (GRCm39)	missense	possibly damaging	0.82
R4534:Tenm2	UTSW	11	35,953,931 (GRCm39)	missense	possibly damaging	0.64
R4539:Tenm2	UTSW	11	35,937,607 (GRCm39)	missense	probably damaging	1.00
R4644:Tenm2	UTSW	11	35,937,963 (GRCm39)	missense	probably benign	0.00
R4661:Tenm2	UTSW	11	35,915,275 (GRCm39)	missense	probably damaging	0.99
R4669:Tenm2	UTSW	11	35,901,314 (GRCm39)	missense	probably damaging	1.00
R4687:Tenm2	UTSW	11	35,939,924 (GRCm39)	missense	probably benign
R4711:Tenm2	UTSW	11	36,191,039 (GRCm39)	missense	probably damaging	0.98
R4816:Tenm2	UTSW	11	35,918,117 (GRCm39)	missense	probably damaging	1.00
R4843:Tenm2	UTSW	11	35,914,847 (GRCm39)	missense	probably damaging	1.00
R4850:Tenm2	UTSW	11	35,914,315 (GRCm39)	nonsense	probably null
R4870:Tenm2	UTSW	11	35,969,396 (GRCm39)	missense	probably damaging	1.00
R5058:Tenm2	UTSW	11	36,097,907 (GRCm39)	missense	possibly damaging	0.80
R5071:Tenm2	UTSW	11	35,959,208 (GRCm39)	missense	probably damaging	0.99
R5073:Tenm2	UTSW	11	35,959,208 (GRCm39)	missense	probably damaging	0.99
R5074:Tenm2	UTSW	11	35,959,208 (GRCm39)	missense	probably damaging	0.99
R5081:Tenm2	UTSW	11	35,915,460 (GRCm39)	missense	possibly damaging	0.95
R5093:Tenm2	UTSW	11	36,834,989 (GRCm39)	missense	probably damaging	1.00
R5170:Tenm2	UTSW	11	35,915,633 (GRCm39)	missense	probably damaging	0.98
R5253:Tenm2	UTSW	11	35,938,028 (GRCm39)	nonsense	probably null
R5343:Tenm2	UTSW	11	35,960,330 (GRCm39)	missense	probably benign	0.00
R5493:Tenm2	UTSW	11	36,755,503 (GRCm39)	missense	probably benign	0.01
R5600:Tenm2	UTSW	11	36,054,541 (GRCm39)	splice site	probably null
R5677:Tenm2	UTSW	11	36,032,510 (GRCm39)	missense	probably damaging	0.98
R5703:Tenm2	UTSW	11	35,914,626 (GRCm39)	missense	probably benign	0.34
R5707:Tenm2	UTSW	11	35,938,009 (GRCm39)	missense	possibly damaging	0.79
R6026:Tenm2	UTSW	11	35,963,556 (GRCm39)	critical splice donor site	probably null
R6063:Tenm2	UTSW	11	36,054,544 (GRCm39)	critical splice donor site	probably null
R6086:Tenm2	UTSW	11	35,899,473 (GRCm39)	missense	possibly damaging	0.64
R6151:Tenm2	UTSW	11	35,899,610 (GRCm39)	missense	probably damaging	1.00
R6169:Tenm2	UTSW	11	36,030,517 (GRCm39)	missense	probably damaging	0.99
R6193:Tenm2	UTSW	11	35,937,621 (GRCm39)	missense	probably damaging	1.00
R6405:Tenm2	UTSW	11	36,755,686 (GRCm39)	missense	probably benign	0.44
R6477:Tenm2	UTSW	11	35,901,334 (GRCm39)	critical splice acceptor site	probably null
R6607:Tenm2	UTSW	11	35,954,602 (GRCm39)	critical splice donor site	probably null
R6668:Tenm2	UTSW	11	35,937,592 (GRCm39)	critical splice donor site	probably null
R6825:Tenm2	UTSW	11	35,937,711 (GRCm39)	missense	probably benign	0.02
R6885:Tenm2	UTSW	11	35,914,407 (GRCm39)	missense	possibly damaging	0.95
R7017:Tenm2	UTSW	11	36,062,236 (GRCm39)	missense	probably damaging	0.98
R7115:Tenm2	UTSW	11	36,054,644 (GRCm39)	missense	probably damaging	0.99
R7153:Tenm2	UTSW	11	35,915,009 (GRCm39)	missense	probably damaging	0.98
R7173:Tenm2	UTSW	11	35,932,378 (GRCm39)	missense	probably damaging	0.99
R7199:Tenm2	UTSW	11	36,062,263 (GRCm39)	missense	probably damaging	1.00
R7205:Tenm2	UTSW	11	35,939,956 (GRCm39)	missense	probably damaging	0.99
R7250:Tenm2	UTSW	11	35,963,625 (GRCm39)	missense	probably damaging	1.00
R7290:Tenm2	UTSW	11	35,914,298 (GRCm39)	missense	probably damaging	1.00
R7366:Tenm2	UTSW	11	35,960,241 (GRCm39)	missense	probably benign	0.09
R7432:Tenm2	UTSW	11	36,755,768 (GRCm39)	missense	probably benign
R7504:Tenm2	UTSW	11	36,030,570 (GRCm39)	missense	probably damaging	1.00
R7513:Tenm2	UTSW	11	35,942,727 (GRCm39)	missense	probably benign	0.34
R7523:Tenm2	UTSW	11	35,969,408 (GRCm39)	splice site	probably null
R7527:Tenm2	UTSW	11	36,097,803 (GRCm39)	missense	probably damaging	1.00
R7648:Tenm2	UTSW	11	35,997,563 (GRCm39)	missense	probably damaging	1.00
R7653:Tenm2	UTSW	11	35,938,174 (GRCm39)	missense	probably benign	0.09
R7717:Tenm2	UTSW	11	36,755,762 (GRCm39)	missense	probably damaging	0.97
R7739:Tenm2	UTSW	11	35,960,388 (GRCm39)	missense	possibly damaging	0.50
R7762:Tenm2	UTSW	11	35,914,133 (GRCm39)	missense	possibly damaging	0.74
R7786:Tenm2	UTSW	11	35,901,276 (GRCm39)	missense	probably damaging	0.99
R7803:Tenm2	UTSW	11	35,937,943 (GRCm39)	missense	probably damaging	0.98
R7834:Tenm2	UTSW	11	35,915,681 (GRCm39)	missense	probably damaging	1.00
R7838:Tenm2	UTSW	11	35,997,626 (GRCm39)	missense	probably benign	0.02
R8073:Tenm2	UTSW	11	36,030,471 (GRCm39)	missense	possibly damaging	0.56
R8076:Tenm2	UTSW	11	35,918,048 (GRCm39)	missense	probably benign	0.23
R8109:Tenm2	UTSW	11	35,899,137 (GRCm39)	missense	probably benign
R8306:Tenm2	UTSW	11	35,960,196 (GRCm39)	missense	possibly damaging	0.52
R8352:Tenm2	UTSW	11	35,914,428 (GRCm39)	missense	probably damaging	0.98
R8452:Tenm2	UTSW	11	35,914,428 (GRCm39)	missense	probably damaging	0.98
R8864:Tenm2	UTSW	11	35,918,022 (GRCm39)	missense	possibly damaging	0.95
R8880:Tenm2	UTSW	11	35,942,788 (GRCm39)	missense	probably damaging	0.99
R8943:Tenm2	UTSW	11	36,834,861 (GRCm39)	missense	probably damaging	0.98
R8969:Tenm2	UTSW	11	35,942,688 (GRCm39)	missense	probably damaging	0.99
R9168:Tenm2	UTSW	11	35,930,722 (GRCm39)	missense	probably damaging	1.00
R9279:Tenm2	UTSW	11	35,959,303 (GRCm39)	missense	probably benign	0.00
R9294:Tenm2	UTSW	11	35,915,327 (GRCm39)	missense	probably damaging	0.98
R9320:Tenm2	UTSW	11	35,914,474 (GRCm39)	missense	probably damaging	0.99
R9373:Tenm2	UTSW	11	35,930,713 (GRCm39)	missense	probably damaging	1.00
R9408:Tenm2	UTSW	11	35,960,246 (GRCm39)	missense	probably damaging	1.00
R9410:Tenm2	UTSW	11	36,032,396 (GRCm39)	missense	probably damaging	0.99
R9454:Tenm2	UTSW	11	36,112,286 (GRCm39)	missense	probably benign
R9489:Tenm2	UTSW	11	36,834,791 (GRCm39)	missense	probably damaging	0.99
R9711:Tenm2	UTSW	11	35,915,341 (GRCm39)	missense	probably damaging	0.99
RF021:Tenm2	UTSW	11	35,915,030 (GRCm39)	missense	possibly damaging	0.95
X0018:Tenm2	UTSW	11	35,915,027 (GRCm39)	missense	probably damaging	1.00
X0063:Tenm2	UTSW	11	35,915,557 (GRCm39)	missense	probably benign
Z1088:Tenm2	UTSW	11	36,164,094 (GRCm39)	missense	probably damaging	1.00
Z1177:Tenm2	UTSW	11	36,191,162 (GRCm39)	missense	probably damaging	0.98
Z1177:Tenm2	UTSW	11	35,899,061 (GRCm39)	missense	possibly damaging	0.95
Z1177:Tenm2	UTSW	11	36,275,957 (GRCm39)	missense	probably benign	0.01

Predicted Primers

PCR Primer
(F):5'- GGATGAGGGACTTTGCGCTTAGAC -3'
(R):5'- AGGACTCGAAGGTTCACCAACATTG -3'

Sequencing Primer
(F):5'- ACTTTGCGCTTAGACAGTAGC -3'
(R):5'- GGTTCACCAACATTGAGTTCCAG -3'

Posted On

2014-05-14