Incidental Mutation 'R1695:Virma'
| ID |
192112 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Virma
|
| Ensembl Gene |
ENSMUSG00000040720 |
| Gene Name |
vir like m6A methyltransferase associated |
| Synonyms |
1110037F02Rik |
| MMRRC Submission |
039728-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1695 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
11485958-11550684 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 11494814 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Lysine
at position 38
(N38K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000058078
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000055372]
[ENSMUST00000059914]
[ENSMUST00000108307]
|
| AlphaFold |
A2AIV2 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000055372
AA Change: N38K
PolyPhen 2
Score 0.981 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000063188
Gene: ENSMUSG00000040720
AA Change: N38K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
139 |
153 |
N/A |
INTRINSIC |
|
low complexity region
|
172 |
198 |
N/A |
INTRINSIC |
|
low complexity region
|
236 |
267 |
N/A |
INTRINSIC |
|
low complexity region
|
276 |
297 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
625 |
N/A |
INTRINSIC |
|
low complexity region
|
1008 |
1020 |
N/A |
INTRINSIC |
|
low complexity region
|
1112 |
1124 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000059914
AA Change: N38K
PolyPhen 2
Score 0.981 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000058078
Gene: ENSMUSG00000040720
AA Change: N38K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
139 |
153 |
N/A |
INTRINSIC |
|
low complexity region
|
172 |
198 |
N/A |
INTRINSIC |
|
low complexity region
|
236 |
267 |
N/A |
INTRINSIC |
|
low complexity region
|
276 |
297 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
625 |
N/A |
INTRINSIC |
|
low complexity region
|
1008 |
1020 |
N/A |
INTRINSIC |
|
low complexity region
|
1112 |
1124 |
N/A |
INTRINSIC |
|
low complexity region
|
1224 |
1232 |
N/A |
INTRINSIC |
|
low complexity region
|
1443 |
1458 |
N/A |
INTRINSIC |
|
low complexity region
|
1460 |
1474 |
N/A |
INTRINSIC |
|
low complexity region
|
1618 |
1634 |
N/A |
INTRINSIC |
|
low complexity region
|
1684 |
1697 |
N/A |
INTRINSIC |
|
low complexity region
|
1750 |
1757 |
N/A |
INTRINSIC |
|
low complexity region
|
1796 |
1808 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108307
AA Change: N38K
PolyPhen 2
Score 0.045 (Sensitivity: 0.94; Specificity: 0.83)
|
| SMART Domains |
Protein: ENSMUSP00000103943
Gene: ENSMUSG00000040720
AA Change: N38K
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:VIR_N
|
5 |
266 |
2e-110 |
PFAM |
|
low complexity region
|
276 |
297 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
625 |
N/A |
INTRINSIC |
|
low complexity region
|
1058 |
1070 |
N/A |
INTRINSIC |
|
low complexity region
|
1162 |
1174 |
N/A |
INTRINSIC |
|
low complexity region
|
1274 |
1282 |
N/A |
INTRINSIC |
|
low complexity region
|
1493 |
1508 |
N/A |
INTRINSIC |
|
low complexity region
|
1510 |
1524 |
N/A |
INTRINSIC |
|
low complexity region
|
1668 |
1684 |
N/A |
INTRINSIC |
|
low complexity region
|
1734 |
1747 |
N/A |
INTRINSIC |
|
low complexity region
|
1800 |
1807 |
N/A |
INTRINSIC |
|
low complexity region
|
1846 |
1858 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.5%
- 20x: 93.2%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam1b |
T |
A |
5: 121,638,970 (GRCm39) |
T692S |
probably benign |
Het |
| Adgrf3 |
T |
A |
5: 30,408,553 (GRCm39) |
N75I |
probably benign |
Het |
| Adgrg5 |
A |
G |
8: 95,664,373 (GRCm39) |
M328V |
probably damaging |
Het |
| Adk |
A |
G |
14: 21,431,668 (GRCm39) |
D286G |
probably benign |
Het |
| Ankrd28 |
T |
A |
14: 31,429,201 (GRCm39) |
D917V |
probably damaging |
Het |
| Appl2 |
C |
T |
10: 83,457,446 (GRCm39) |
D141N |
probably damaging |
Het |
| Arfgef2 |
T |
C |
2: 166,706,632 (GRCm39) |
V952A |
probably damaging |
Het |
| Arpc2 |
T |
A |
1: 74,287,391 (GRCm39) |
H70Q |
probably damaging |
Het |
| Bpifa5 |
T |
C |
2: 154,009,580 (GRCm39) |
L261P |
probably damaging |
Het |
| Brca1 |
G |
T |
11: 101,415,281 (GRCm39) |
T951K |
probably damaging |
Het |
| Ccdc73 |
A |
T |
2: 104,822,450 (GRCm39) |
S800C |
probably damaging |
Het |
| Cdh15 |
C |
G |
8: 123,588,755 (GRCm39) |
D276E |
probably benign |
Het |
| Cfap119 |
A |
G |
7: 127,186,745 (GRCm39) |
|
probably null |
Het |
| Cfap418 |
T |
A |
4: 10,874,644 (GRCm39) |
D10E |
probably damaging |
Het |
| Cfh |
T |
C |
1: 140,030,575 (GRCm39) |
I551V |
probably damaging |
Het |
| Chd7 |
T |
A |
4: 8,833,960 (GRCm39) |
L1238Q |
probably damaging |
Het |
| Chd9 |
T |
G |
8: 91,728,410 (GRCm39) |
F1275L |
probably damaging |
Het |
| Chrnb3 |
A |
G |
8: 27,883,728 (GRCm39) |
Y155C |
probably damaging |
Het |
| Cltc |
C |
A |
11: 86,591,886 (GRCm39) |
|
probably null |
Het |
| Ctsll3 |
T |
A |
13: 60,948,791 (GRCm39) |
N55Y |
probably damaging |
Het |
| Cysltr2 |
T |
C |
14: 73,267,321 (GRCm39) |
M130V |
probably benign |
Het |
| Daglb |
T |
C |
5: 143,480,361 (GRCm39) |
M455T |
probably benign |
Het |
| Dbn1 |
A |
G |
13: 55,624,521 (GRCm39) |
S343P |
probably benign |
Het |
| Dnah2 |
T |
A |
11: 69,405,517 (GRCm39) |
D665V |
possibly damaging |
Het |
| Dusp6 |
T |
A |
10: 99,099,555 (GRCm39) |
M1K |
probably null |
Het |
| Eif3m |
T |
C |
2: 104,847,298 (GRCm39) |
E12G |
probably damaging |
Het |
| Epha2 |
T |
C |
4: 141,033,828 (GRCm39) |
V29A |
possibly damaging |
Het |
| Farp2 |
T |
A |
1: 93,488,047 (GRCm39) |
N91K |
probably damaging |
Het |
| Ferd3l |
C |
A |
12: 33,978,971 (GRCm39) |
S161R |
probably benign |
Het |
| Fgd2 |
A |
T |
17: 29,587,219 (GRCm39) |
D315V |
possibly damaging |
Het |
| Fhip2a |
T |
C |
19: 57,367,603 (GRCm39) |
W337R |
probably damaging |
Het |
| Fstl4 |
T |
A |
11: 53,056,705 (GRCm39) |
|
probably null |
Het |
| Grm5 |
A |
G |
7: 87,685,311 (GRCm39) |
D476G |
possibly damaging |
Het |
| Gtf3c3 |
C |
T |
1: 54,456,937 (GRCm39) |
A488T |
probably damaging |
Het |
| Hdlbp |
A |
G |
1: 93,364,922 (GRCm39) |
L115P |
probably damaging |
Het |
| Hk2 |
T |
A |
6: 82,721,932 (GRCm39) |
N136Y |
probably damaging |
Het |
| Hs2st1 |
G |
T |
3: 144,140,415 (GRCm39) |
A302E |
probably benign |
Het |
| Htr7 |
T |
C |
19: 35,947,136 (GRCm39) |
N293D |
probably benign |
Het |
| Ikbkb |
T |
A |
8: 23,163,496 (GRCm39) |
E271D |
probably benign |
Het |
| Il5ra |
A |
T |
6: 106,715,335 (GRCm39) |
Y166* |
probably null |
Het |
| Il9r |
T |
A |
11: 32,143,227 (GRCm39) |
H244L |
probably benign |
Het |
| Itih4 |
T |
C |
14: 30,613,456 (GRCm39) |
|
probably null |
Het |
| Kirrel1 |
C |
T |
3: 86,996,458 (GRCm39) |
M380I |
probably null |
Het |
| Large1 |
A |
T |
8: 73,544,710 (GRCm39) |
D689E |
probably damaging |
Het |
| Limk2 |
A |
G |
11: 3,303,275 (GRCm39) |
|
probably null |
Het |
| Med15 |
A |
G |
16: 17,540,644 (GRCm39) |
F34S |
probably damaging |
Het |
| Mprip |
C |
T |
11: 59,643,357 (GRCm39) |
T505I |
probably damaging |
Het |
| Mtor |
T |
A |
4: 148,623,364 (GRCm39) |
N2071K |
probably benign |
Het |
| Muc16 |
A |
G |
9: 18,408,729 (GRCm39) |
L2522P |
probably damaging |
Het |
| Myd88 |
A |
T |
9: 119,166,908 (GRCm39) |
|
probably null |
Het |
| Myo7a |
A |
C |
7: 97,741,703 (GRCm39) |
F484V |
possibly damaging |
Het |
| Nme1 |
A |
C |
11: 93,851,593 (GRCm39) |
L81R |
probably benign |
Het |
| Ntn4 |
T |
A |
10: 93,569,464 (GRCm39) |
|
probably null |
Het |
| Or2y13 |
T |
C |
11: 49,415,162 (GRCm39) |
V204A |
probably benign |
Het |
| Or4p19 |
T |
C |
2: 88,242,444 (GRCm39) |
D186G |
probably damaging |
Het |
| Or51l4 |
A |
T |
7: 103,404,131 (GRCm39) |
Y220* |
probably null |
Het |
| Otogl |
T |
G |
10: 107,649,878 (GRCm39) |
N1159T |
probably damaging |
Het |
| Pabpc6 |
G |
A |
17: 9,887,003 (GRCm39) |
T516I |
probably benign |
Het |
| Pcdh1 |
C |
T |
18: 38,335,921 (GRCm39) |
R238H |
probably damaging |
Het |
| Pex5l |
T |
A |
3: 33,008,531 (GRCm39) |
N151I |
probably benign |
Het |
| Plekha7 |
T |
C |
7: 115,727,920 (GRCm39) |
N980S |
probably damaging |
Het |
| Reg4 |
C |
T |
3: 98,143,677 (GRCm39) |
T157I |
probably benign |
Het |
| Rev3l |
G |
T |
10: 39,700,611 (GRCm39) |
E1703* |
probably null |
Het |
| Rev3l |
A |
T |
10: 39,700,612 (GRCm39) |
E1703V |
probably damaging |
Het |
| Rsf1 |
GCG |
GCGACG |
7: 97,229,114 (GRCm39) |
|
probably benign |
Het |
| Saal1 |
T |
C |
7: 46,342,340 (GRCm39) |
K368E |
probably damaging |
Het |
| Scn9a |
C |
T |
2: 66,335,220 (GRCm39) |
W1245* |
probably null |
Het |
| Slc38a11 |
T |
A |
2: 65,147,315 (GRCm39) |
L387F |
probably damaging |
Het |
| Sned1 |
G |
A |
1: 93,209,376 (GRCm39) |
V830M |
possibly damaging |
Het |
| Sptb |
C |
A |
12: 76,667,641 (GRCm39) |
V819L |
probably benign |
Het |
| Sptbn1 |
T |
C |
11: 30,086,124 (GRCm39) |
T1195A |
probably benign |
Het |
| Ssna1 |
C |
A |
2: 25,162,024 (GRCm39) |
V57F |
possibly damaging |
Het |
| Stk32a |
G |
T |
18: 43,446,485 (GRCm39) |
E312* |
probably null |
Het |
| Synpo |
A |
G |
18: 60,736,459 (GRCm39) |
F496L |
probably benign |
Het |
| Syt15 |
C |
T |
14: 33,944,858 (GRCm39) |
T135M |
probably benign |
Het |
| Tm9sf4 |
A |
G |
2: 153,032,832 (GRCm39) |
E246G |
probably benign |
Het |
| Trim44 |
T |
C |
2: 102,187,830 (GRCm39) |
M308V |
possibly damaging |
Het |
| Unc119b |
T |
A |
5: 115,272,885 (GRCm39) |
K29* |
probably null |
Het |
| Vim |
T |
A |
2: 13,584,921 (GRCm39) |
D367E |
probably benign |
Het |
| Vmn1r228 |
A |
T |
17: 20,996,560 (GRCm39) |
D319E |
possibly damaging |
Het |
| Vmn2r32 |
T |
A |
7: 7,466,991 (GRCm39) |
I846F |
probably benign |
Het |
| Vps13b |
T |
C |
15: 35,576,667 (GRCm39) |
V1025A |
probably benign |
Het |
| Vps13c |
G |
T |
9: 67,879,357 (GRCm39) |
E566* |
probably null |
Het |
|
| Other mutations in Virma |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00428:Virma
|
APN |
4 |
11,519,424 (GRCm39) |
splice site |
probably benign |
|
|
IGL00477:Virma
|
APN |
4 |
11,519,006 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01293:Virma
|
APN |
4 |
11,521,114 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01410:Virma
|
APN |
4 |
11,518,929 (GRCm39) |
nonsense |
probably null |
|
|
IGL01531:Virma
|
APN |
4 |
11,528,753 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01672:Virma
|
APN |
4 |
11,527,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01724:Virma
|
APN |
4 |
11,528,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01747:Virma
|
APN |
4 |
11,526,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01776:Virma
|
APN |
4 |
11,527,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02064:Virma
|
APN |
4 |
11,513,163 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL02243:Virma
|
APN |
4 |
11,546,031 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02244:Virma
|
APN |
4 |
11,546,031 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02445:Virma
|
APN |
4 |
11,527,029 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02546:Virma
|
APN |
4 |
11,494,804 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02807:Virma
|
APN |
4 |
11,507,079 (GRCm39) |
splice site |
probably benign |
|
|
IGL02967:Virma
|
APN |
4 |
11,514,096 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03211:Virma
|
APN |
4 |
11,548,770 (GRCm39) |
nonsense |
probably null |
|
|
IGL03242:Virma
|
APN |
4 |
11,527,669 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
IGL03256:Virma
|
APN |
4 |
11,542,207 (GRCm39) |
splice site |
probably benign |
|
|
IGL03327:Virma
|
APN |
4 |
11,518,984 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03346:Virma
|
APN |
4 |
11,518,984 (GRCm39) |
missense |
probably benign |
0.00 |
|
PIT4802001:Virma
|
UTSW |
4 |
11,546,008 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0142:Virma
|
UTSW |
4 |
11,548,783 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0355:Virma
|
UTSW |
4 |
11,528,626 (GRCm39) |
nonsense |
probably null |
|
|
R0522:Virma
|
UTSW |
4 |
11,519,416 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0600:Virma
|
UTSW |
4 |
11,498,769 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1435:Virma
|
UTSW |
4 |
11,528,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1489:Virma
|
UTSW |
4 |
11,521,164 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1568:Virma
|
UTSW |
4 |
11,528,776 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1616:Virma
|
UTSW |
4 |
11,544,954 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1655:Virma
|
UTSW |
4 |
11,494,786 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1835:Virma
|
UTSW |
4 |
11,540,511 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1951:Virma
|
UTSW |
4 |
11,513,907 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1991:Virma
|
UTSW |
4 |
11,519,242 (GRCm39) |
missense |
probably benign |
0.06 |
|
R2145:Virma
|
UTSW |
4 |
11,548,726 (GRCm39) |
splice site |
probably benign |
|
|
R2172:Virma
|
UTSW |
4 |
11,527,843 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R2217:Virma
|
UTSW |
4 |
11,544,924 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2218:Virma
|
UTSW |
4 |
11,544,924 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2248:Virma
|
UTSW |
4 |
11,518,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2342:Virma
|
UTSW |
4 |
11,501,316 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3424:Virma
|
UTSW |
4 |
11,513,177 (GRCm39) |
nonsense |
probably null |
|
|
R4397:Virma
|
UTSW |
4 |
11,513,901 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4449:Virma
|
UTSW |
4 |
11,498,828 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4660:Virma
|
UTSW |
4 |
11,513,505 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4698:Virma
|
UTSW |
4 |
11,528,636 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4878:Virma
|
UTSW |
4 |
11,544,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4937:Virma
|
UTSW |
4 |
11,521,147 (GRCm39) |
nonsense |
probably null |
|
|
R5031:Virma
|
UTSW |
4 |
11,542,116 (GRCm39) |
nonsense |
probably null |
|
|
R5040:Virma
|
UTSW |
4 |
11,528,746 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5061:Virma
|
UTSW |
4 |
11,494,840 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5091:Virma
|
UTSW |
4 |
11,519,392 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5137:Virma
|
UTSW |
4 |
11,546,297 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5262:Virma
|
UTSW |
4 |
11,539,926 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5297:Virma
|
UTSW |
4 |
11,494,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5730:Virma
|
UTSW |
4 |
11,542,154 (GRCm39) |
missense |
probably benign |
0.44 |
|
R5818:Virma
|
UTSW |
4 |
11,513,319 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5835:Virma
|
UTSW |
4 |
11,514,036 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6125:Virma
|
UTSW |
4 |
11,521,172 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6197:Virma
|
UTSW |
4 |
11,505,498 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6222:Virma
|
UTSW |
4 |
11,527,820 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6793:Virma
|
UTSW |
4 |
11,539,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7028:Virma
|
UTSW |
4 |
11,519,249 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R7356:Virma
|
UTSW |
4 |
11,513,595 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7383:Virma
|
UTSW |
4 |
11,514,026 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7391:Virma
|
UTSW |
4 |
11,508,099 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7425:Virma
|
UTSW |
4 |
11,546,211 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7556:Virma
|
UTSW |
4 |
11,518,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7715:Virma
|
UTSW |
4 |
11,513,016 (GRCm39) |
splice site |
probably null |
|
|
R7715:Virma
|
UTSW |
4 |
11,549,682 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7986:Virma
|
UTSW |
4 |
11,540,023 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7990:Virma
|
UTSW |
4 |
11,513,983 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8048:Virma
|
UTSW |
4 |
11,539,918 (GRCm39) |
nonsense |
probably null |
|
|
R8050:Virma
|
UTSW |
4 |
11,528,643 (GRCm39) |
missense |
probably benign |
0.22 |
|
R8165:Virma
|
UTSW |
4 |
11,542,128 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8412:Virma
|
UTSW |
4 |
11,521,261 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8544:Virma
|
UTSW |
4 |
11,516,949 (GRCm39) |
missense |
probably benign |
|
|
R8551:Virma
|
UTSW |
4 |
11,513,397 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8699:Virma
|
UTSW |
4 |
11,528,678 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8739:Virma
|
UTSW |
4 |
11,540,643 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8950:Virma
|
UTSW |
4 |
11,519,047 (GRCm39) |
nonsense |
probably null |
|
|
R9015:Virma
|
UTSW |
4 |
11,540,494 (GRCm39) |
missense |
probably benign |
0.27 |
|
R9038:Virma
|
UTSW |
4 |
11,526,922 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9115:Virma
|
UTSW |
4 |
11,498,744 (GRCm39) |
missense |
probably benign |
0.15 |
|
R9294:Virma
|
UTSW |
4 |
11,513,507 (GRCm39) |
nonsense |
probably null |
|
|
R9404:Virma
|
UTSW |
4 |
11,513,626 (GRCm39) |
missense |
probably benign |
0.17 |
|
R9477:Virma
|
UTSW |
4 |
11,528,753 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9532:Virma
|
UTSW |
4 |
11,507,078 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9649:Virma
|
UTSW |
4 |
11,486,045 (GRCm39) |
start codon destroyed |
probably null |
0.08 |
|
R9657:Virma
|
UTSW |
4 |
11,544,898 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9780:Virma
|
UTSW |
4 |
11,513,442 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R9800:Virma
|
UTSW |
4 |
11,546,007 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0020:Virma
|
UTSW |
4 |
11,486,055 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTTTTAGTGATGAGGGTTCAACCCAGG -3'
(R):5'- TCTATCTCCAACACATAGGGGCTGC -3'
Sequencing Primer
(F):5'- cccaagtgccaggattagag -3'
(R):5'- CACCCATATGCTCTGTTGTCAG -3'
|
| Posted On |
2014-05-14 |
Incidental Mutation