Incidental Mutation 'R1764:Sned1'
| ID |
193242 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Sned1
|
| Ensembl Gene |
ENSMUSG00000047793 |
| Gene Name |
sushi, nidogen and EGF-like domains 1 |
| Synonyms |
D430044C15Rik, 6720455I24Rik, Snep |
| MMRRC Submission |
039796-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.080)
|
| Stock # |
R1764 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
93163563-93228787 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 93209376 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Methionine
at position 830
(V830M)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000050832
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000062202]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000062202
AA Change: V830M
PolyPhen 2
Score 0.895 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000050832
Gene: ENSMUSG00000047793
AA Change: V830M
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
24 |
N/A |
INTRINSIC |
|
NIDO
|
103 |
260 |
2.98e-54 |
SMART |
|
EGF
|
271 |
309 |
3.79e-6 |
SMART |
|
EGF_CA
|
311 |
347 |
2.42e-13 |
SMART |
|
EGF
|
352 |
385 |
1.02e-6 |
SMART |
|
EGF_CA
|
387 |
423 |
1.91e-11 |
SMART |
|
EGF
|
432 |
465 |
2.96e-8 |
SMART |
|
EGF
|
471 |
500 |
6.02e0 |
SMART |
|
EGF
|
544 |
577 |
3.54e-6 |
SMART |
|
EGF
|
583 |
616 |
6.06e-5 |
SMART |
|
EGF_CA
|
619 |
655 |
2.33e-6 |
SMART |
|
EGF
|
660 |
693 |
1.77e-6 |
SMART |
|
CCP
|
698 |
751 |
2.5e-11 |
SMART |
|
EGF_CA
|
753 |
789 |
1.66e-11 |
SMART |
|
EGF_CA
|
791 |
827 |
1.38e-8 |
SMART |
|
EGF_CA
|
829 |
865 |
1.92e-7 |
SMART |
|
EGF
|
870 |
903 |
2.35e-2 |
SMART |
|
FN3
|
906 |
991 |
1.7e-4 |
SMART |
|
FN3
|
1005 |
1084 |
1.38e-4 |
SMART |
|
FN3
|
1104 |
1185 |
1.6e-9 |
SMART |
|
EGF
|
1309 |
1342 |
6.16e-6 |
SMART |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000163688
AA Change: V39M
|
| SMART Domains |
Protein: ENSMUSP00000132455
Gene: ENSMUSG00000047793
AA Change: V39M
| Domain | Start | End | E-Value | Type |
|---|
|
EGF_CA
|
1 |
37 |
6.7e-7 |
SMART |
|
EGF_CA
|
39 |
75 |
1.92e-7 |
SMART |
|
EGF
|
80 |
113 |
2.35e-2 |
SMART |
|
FN3
|
116 |
201 |
1.7e-4 |
SMART |
|
FN3
|
215 |
294 |
1.38e-4 |
SMART |
|
FN3
|
314 |
395 |
1.6e-9 |
SMART |
|
EGF
|
487 |
520 |
6.16e-6 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000165843
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000172289
|
| Meta Mutation Damage Score |
0.1152 |
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.1%
- 20x: 92.2%
|
| Validation Efficiency |
94% (94/100) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 95 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930522L14Rik |
A |
G |
5: 109,884,655 (GRCm39) |
V401A |
probably benign |
Het |
| Abca7 |
G |
T |
10: 79,844,784 (GRCm39) |
W1502L |
probably damaging |
Het |
| Adcy7 |
A |
G |
8: 89,035,468 (GRCm39) |
E124G |
probably benign |
Het |
| Aif1l |
G |
A |
2: 31,855,118 (GRCm39) |
E66K |
probably benign |
Het |
| Aldh8a1 |
A |
T |
10: 21,271,392 (GRCm39) |
M373L |
probably benign |
Het |
| Alg6 |
T |
C |
4: 99,629,815 (GRCm39) |
Y131H |
probably benign |
Het |
| Arhgef6 |
T |
C |
X: 56,383,922 (GRCm39) |
M5V |
probably benign |
Het |
| Arrdc4 |
A |
T |
7: 68,391,622 (GRCm39) |
I215K |
probably damaging |
Het |
| Asb4 |
A |
G |
6: 5,390,798 (GRCm39) |
|
probably null |
Het |
| Astn1 |
T |
C |
1: 158,331,821 (GRCm39) |
I305T |
probably benign |
Het |
| Atp5f1b |
T |
A |
10: 127,919,949 (GRCm39) |
|
probably benign |
Het |
| Atp8a1 |
C |
A |
5: 67,788,910 (GRCm39) |
M1044I |
probably benign |
Het |
| Atp9b |
C |
T |
18: 80,952,806 (GRCm39) |
|
probably null |
Het |
| Brd10 |
T |
A |
19: 29,696,560 (GRCm39) |
T978S |
possibly damaging |
Het |
| Btaf1 |
A |
G |
19: 36,928,518 (GRCm39) |
H113R |
probably benign |
Het |
| C87436 |
G |
T |
6: 86,430,594 (GRCm39) |
C338F |
possibly damaging |
Het |
| Casz1 |
T |
C |
4: 149,027,357 (GRCm39) |
|
probably benign |
Het |
| Cbr3 |
T |
A |
16: 93,487,370 (GRCm39) |
H184Q |
probably damaging |
Het |
| Cct8l1 |
T |
C |
5: 25,722,097 (GRCm39) |
S271P |
possibly damaging |
Het |
| Cdc34 |
A |
G |
10: 79,521,174 (GRCm39) |
K77R |
probably benign |
Het |
| Cdc34 |
G |
T |
10: 79,521,172 (GRCm39) |
|
probably null |
Het |
| Cdh20 |
A |
G |
1: 104,862,070 (GRCm39) |
|
probably benign |
Het |
| Celsr3 |
A |
G |
9: 108,706,157 (GRCm39) |
E880G |
probably damaging |
Het |
| Cers1 |
T |
G |
8: 70,774,141 (GRCm39) |
|
probably null |
Het |
| Cntn5 |
T |
C |
9: 9,673,988 (GRCm39) |
I705V |
probably benign |
Het |
| Dennd4c |
T |
A |
4: 86,721,247 (GRCm39) |
D636E |
probably damaging |
Het |
| Dnah11 |
T |
C |
12: 118,154,560 (GRCm39) |
E240G |
probably benign |
Het |
| Dnah2 |
T |
C |
11: 69,314,369 (GRCm39) |
Y4100C |
probably damaging |
Het |
| Dpysl3 |
T |
C |
18: 43,496,583 (GRCm39) |
E151G |
probably damaging |
Het |
| Efcab9 |
T |
G |
11: 32,474,457 (GRCm39) |
T9P |
possibly damaging |
Het |
| Eif4g2 |
A |
T |
7: 110,673,694 (GRCm39) |
F725Y |
probably damaging |
Het |
| Epha6 |
T |
A |
16: 59,596,091 (GRCm39) |
I867F |
probably null |
Het |
| Erbin |
T |
C |
13: 103,979,959 (GRCm39) |
|
probably benign |
Het |
| Evi5l |
A |
G |
8: 4,253,560 (GRCm39) |
E468G |
probably damaging |
Het |
| Filip1l |
C |
T |
16: 57,390,401 (GRCm39) |
R330W |
probably damaging |
Het |
| Fmo3 |
C |
T |
1: 162,786,142 (GRCm39) |
V283M |
possibly damaging |
Het |
| Gabarapl1 |
A |
T |
6: 129,510,481 (GRCm39) |
K24N |
possibly damaging |
Het |
| Gigyf1 |
C |
T |
5: 137,520,770 (GRCm39) |
|
probably benign |
Het |
| Gm5581 |
T |
A |
6: 131,158,362 (GRCm39) |
|
noncoding transcript |
Het |
| Gon4l |
G |
T |
3: 88,799,906 (GRCm39) |
K850N |
probably damaging |
Het |
| Igf2bp3 |
C |
T |
6: 49,085,980 (GRCm39) |
R233H |
probably damaging |
Het |
| Iqcf4 |
G |
A |
9: 106,445,893 (GRCm39) |
R85C |
probably benign |
Het |
| Kalrn |
C |
T |
16: 34,033,243 (GRCm39) |
R473Q |
probably damaging |
Het |
| Lmod2 |
T |
A |
6: 24,603,376 (GRCm39) |
V117E |
probably damaging |
Het |
| Mapk11 |
A |
G |
15: 89,028,594 (GRCm39) |
|
probably null |
Het |
| Mcm3 |
G |
A |
1: 20,876,103 (GRCm39) |
R664C |
probably damaging |
Het |
| Mex3d |
A |
G |
10: 80,222,770 (GRCm39) |
M162T |
probably benign |
Het |
| Mrgprb3 |
A |
G |
7: 48,292,771 (GRCm39) |
I260T |
probably benign |
Het |
| Ncor2 |
G |
T |
5: 125,105,679 (GRCm39) |
A1637D |
possibly damaging |
Het |
| Nedd4 |
T |
A |
9: 72,638,189 (GRCm39) |
D441E |
probably damaging |
Het |
| Nek5 |
A |
T |
8: 22,599,928 (GRCm39) |
C194S |
probably damaging |
Het |
| Nos1ap |
T |
C |
1: 170,146,447 (GRCm39) |
D369G |
possibly damaging |
Het |
| Ntrk1 |
G |
T |
3: 87,687,391 (GRCm39) |
T681K |
probably damaging |
Het |
| Or13a24 |
T |
C |
7: 140,154,383 (GRCm39) |
W106R |
probably damaging |
Het |
| Or4f14 |
A |
G |
2: 111,742,526 (GRCm39) |
F250L |
possibly damaging |
Het |
| Otogl |
C |
T |
10: 107,735,322 (GRCm39) |
W154* |
probably null |
Het |
| Pcdh20 |
T |
C |
14: 88,706,620 (GRCm39) |
T227A |
possibly damaging |
Het |
| Pcdhb17 |
T |
C |
18: 37,620,324 (GRCm39) |
S705P |
probably damaging |
Het |
| Piezo2 |
T |
C |
18: 63,257,713 (GRCm39) |
H335R |
possibly damaging |
Het |
| Pkn2 |
T |
C |
3: 142,499,615 (GRCm39) |
Q954R |
probably damaging |
Het |
| Pramel23 |
C |
A |
4: 143,424,840 (GRCm39) |
C201F |
probably benign |
Het |
| Prkcq |
G |
A |
2: 11,237,442 (GRCm39) |
V74M |
probably damaging |
Het |
| Prkrip1 |
A |
T |
5: 136,218,489 (GRCm39) |
|
probably null |
Het |
| Pttg1ip2 |
A |
T |
5: 5,528,943 (GRCm39) |
I24N |
possibly damaging |
Het |
| Rb1cc1 |
A |
G |
1: 6,284,904 (GRCm39) |
|
probably benign |
Het |
| Rbm5 |
A |
T |
9: 107,644,763 (GRCm39) |
Y11* |
probably null |
Het |
| Rsf1 |
CG |
CGACGGCGGTG |
7: 97,229,115 (GRCm39) |
|
probably benign |
Het |
| Ryr3 |
C |
A |
2: 112,690,805 (GRCm39) |
V1082L |
probably damaging |
Het |
| Scart2 |
A |
G |
7: 139,877,178 (GRCm39) |
E831G |
probably benign |
Het |
| Sel1l3 |
C |
A |
5: 53,327,789 (GRCm39) |
E497* |
probably null |
Het |
| Serpina6 |
A |
T |
12: 103,620,182 (GRCm39) |
I189N |
probably damaging |
Het |
| Serpinb11 |
A |
T |
1: 107,304,532 (GRCm39) |
T166S |
probably benign |
Het |
| Skint7 |
T |
C |
4: 111,839,270 (GRCm39) |
L188S |
probably benign |
Het |
| Slc25a45 |
C |
T |
19: 5,934,958 (GRCm39) |
A269V |
probably damaging |
Het |
| Sltm |
A |
G |
9: 70,469,082 (GRCm39) |
T114A |
probably benign |
Het |
| Spen |
C |
A |
4: 141,200,261 (GRCm39) |
V2766L |
probably damaging |
Het |
| Srgap2 |
T |
A |
1: 131,247,275 (GRCm39) |
I445F |
possibly damaging |
Het |
| Stox2 |
A |
T |
8: 47,647,051 (GRCm39) |
Y200* |
probably null |
Het |
| Strada |
C |
A |
11: 106,055,010 (GRCm39) |
R384L |
probably damaging |
Het |
| Tctn2 |
G |
A |
5: 124,757,094 (GRCm39) |
|
noncoding transcript |
Het |
| Tgfbr3l |
G |
T |
8: 4,299,282 (GRCm39) |
R461L |
probably benign |
Het |
| Tmem65 |
A |
G |
15: 58,661,998 (GRCm39) |
|
probably benign |
Het |
| Tpst1 |
G |
T |
5: 130,143,343 (GRCm39) |
V294F |
possibly damaging |
Het |
| Trim23 |
A |
G |
13: 104,335,126 (GRCm39) |
Y384C |
probably damaging |
Het |
| Ube3b |
C |
G |
5: 114,542,678 (GRCm39) |
L512V |
possibly damaging |
Het |
| Ubxn4 |
T |
A |
1: 128,183,916 (GRCm39) |
V92E |
probably damaging |
Het |
| Vmn2r57 |
A |
T |
7: 41,050,067 (GRCm39) |
C561S |
probably damaging |
Het |
| Vwa8 |
A |
G |
14: 79,145,635 (GRCm39) |
D104G |
probably damaging |
Het |
| Wdr25 |
T |
A |
12: 108,992,364 (GRCm39) |
L73* |
probably null |
Het |
| Wnt9a |
G |
A |
11: 59,221,728 (GRCm39) |
A209T |
probably benign |
Het |
| Zcchc17 |
A |
C |
4: 130,223,388 (GRCm39) |
C133G |
probably damaging |
Het |
| Zdhhc18 |
T |
A |
4: 133,335,987 (GRCm39) |
M375L |
probably benign |
Het |
| Zfhx3 |
T |
C |
8: 109,678,276 (GRCm39) |
F3109L |
probably benign |
Het |
| Zfp202 |
T |
A |
9: 40,121,762 (GRCm39) |
D286E |
probably benign |
Het |
| Zzef1 |
T |
C |
11: 72,784,158 (GRCm39) |
L2021P |
probably benign |
Het |
|
| Other mutations in Sned1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00785:Sned1
|
APN |
1 |
93,201,891 (GRCm39) |
splice site |
probably benign |
|
|
IGL00955:Sned1
|
APN |
1 |
93,202,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01367:Sned1
|
APN |
1 |
93,210,936 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL02116:Sned1
|
APN |
1 |
93,209,447 (GRCm39) |
nonsense |
probably null |
|
|
IGL02195:Sned1
|
APN |
1 |
93,201,882 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02390:Sned1
|
APN |
1 |
93,189,386 (GRCm39) |
missense |
probably benign |
|
|
IGL02423:Sned1
|
APN |
1 |
93,211,322 (GRCm39) |
missense |
probably benign |
|
|
IGL02451:Sned1
|
APN |
1 |
93,163,930 (GRCm39) |
splice site |
probably benign |
|
|
IGL02567:Sned1
|
APN |
1 |
93,202,069 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03184:Sned1
|
APN |
1 |
93,202,390 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03328:Sned1
|
APN |
1 |
93,217,089 (GRCm39) |
missense |
probably benign |
|
|
Bulger
|
UTSW |
1 |
93,199,385 (GRCm39) |
nonsense |
probably null |
|
|
farina
|
UTSW |
1 |
93,209,374 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Millet
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
triticale
|
UTSW |
1 |
93,281,654 (GRCm39) |
missense |
|
|
|
R0257:Sned1
|
UTSW |
1 |
93,192,819 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R0372:Sned1
|
UTSW |
1 |
93,213,673 (GRCm39) |
splice site |
probably benign |
|
|
R0525:Sned1
|
UTSW |
1 |
93,199,696 (GRCm39) |
splice site |
probably null |
|
|
R0727:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0759:Sned1
|
UTSW |
1 |
93,200,286 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0965:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0968:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0969:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1006:Sned1
|
UTSW |
1 |
93,184,114 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1068:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1069:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1070:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1112:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1113:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1114:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1115:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1118:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1119:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1144:Sned1
|
UTSW |
1 |
93,208,298 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1228:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1230:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1231:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1313:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1313:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1340:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1382:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1383:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1394:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1395:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1397:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1414:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1430:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1432:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1473:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1503:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1563:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1565:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1689:Sned1
|
UTSW |
1 |
93,211,094 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1695:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1734:Sned1
|
UTSW |
1 |
93,187,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1767:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1896:Sned1
|
UTSW |
1 |
93,192,769 (GRCm39) |
missense |
probably benign |
0.16 |
|
R1916:Sned1
|
UTSW |
1 |
93,201,884 (GRCm39) |
missense |
probably null |
1.00 |
|
R1945:Sned1
|
UTSW |
1 |
93,198,960 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1972:Sned1
|
UTSW |
1 |
93,192,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1973:Sned1
|
UTSW |
1 |
93,192,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2143:Sned1
|
UTSW |
1 |
93,199,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2144:Sned1
|
UTSW |
1 |
93,199,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2145:Sned1
|
UTSW |
1 |
93,199,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2153:Sned1
|
UTSW |
1 |
93,202,379 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2273:Sned1
|
UTSW |
1 |
93,209,364 (GRCm39) |
splice site |
probably null |
|
|
R2274:Sned1
|
UTSW |
1 |
93,209,364 (GRCm39) |
splice site |
probably null |
|
|
R2275:Sned1
|
UTSW |
1 |
93,209,364 (GRCm39) |
splice site |
probably null |
|
|
R2340:Sned1
|
UTSW |
1 |
93,184,174 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3237:Sned1
|
UTSW |
1 |
93,186,725 (GRCm39) |
missense |
probably benign |
0.21 |
|
R3747:Sned1
|
UTSW |
1 |
93,189,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3879:Sned1
|
UTSW |
1 |
93,192,752 (GRCm39) |
splice site |
probably benign |
|
|
R4281:Sned1
|
UTSW |
1 |
93,213,577 (GRCm39) |
nonsense |
probably null |
|
|
R4282:Sned1
|
UTSW |
1 |
93,213,577 (GRCm39) |
nonsense |
probably null |
|
|
R4356:Sned1
|
UTSW |
1 |
93,193,113 (GRCm39) |
splice site |
probably null |
|
|
R4358:Sned1
|
UTSW |
1 |
93,202,381 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4677:Sned1
|
UTSW |
1 |
93,224,019 (GRCm39) |
unclassified |
probably benign |
|
|
R5291:Sned1
|
UTSW |
1 |
93,223,446 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5340:Sned1
|
UTSW |
1 |
93,210,479 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5542:Sned1
|
UTSW |
1 |
93,199,324 (GRCm39) |
missense |
probably benign |
|
|
R5582:Sned1
|
UTSW |
1 |
93,210,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5874:Sned1
|
UTSW |
1 |
93,193,067 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6159:Sned1
|
UTSW |
1 |
93,210,659 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6175:Sned1
|
UTSW |
1 |
93,203,196 (GRCm39) |
splice site |
probably null |
|
|
R6445:Sned1
|
UTSW |
1 |
93,211,318 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6631:Sned1
|
UTSW |
1 |
93,209,374 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7018:Sned1
|
UTSW |
1 |
93,212,143 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7035:Sned1
|
UTSW |
1 |
93,189,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7047:Sned1
|
UTSW |
1 |
93,213,540 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R7347:Sned1
|
UTSW |
1 |
93,209,458 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7427:Sned1
|
UTSW |
1 |
93,217,080 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7581:Sned1
|
UTSW |
1 |
93,184,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7679:Sned1
|
UTSW |
1 |
93,163,760 (GRCm39) |
missense |
unknown |
|
|
R7899:Sned1
|
UTSW |
1 |
93,201,804 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8093:Sned1
|
UTSW |
1 |
93,202,387 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8124:Sned1
|
UTSW |
1 |
93,210,711 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8489:Sned1
|
UTSW |
1 |
93,210,978 (GRCm39) |
nonsense |
probably null |
|
|
R9012:Sned1
|
UTSW |
1 |
93,212,320 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9290:Sned1
|
UTSW |
1 |
93,199,385 (GRCm39) |
nonsense |
probably null |
|
|
R9560:Sned1
|
UTSW |
1 |
93,202,110 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9775:Sned1
|
UTSW |
1 |
93,199,604 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0025:Sned1
|
UTSW |
1 |
93,189,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Sned1
|
UTSW |
1 |
93,186,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Sned1
|
UTSW |
1 |
93,213,542 (GRCm39) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCATCCTCTTGCTGGACAAGCTAC -3'
(R):5'- TCCTGAAAAGCCTGACCAAGTGTG -3'
Sequencing Primer
(F):5'- TTGCTGGACAAGCTACTCAGAG -3'
(R):5'- GCCTATCCAGGGACAACAGAG -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation