Incidental Mutation 'R1750:Fan1'
| ID |
193397 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Fan1
|
| Ensembl Gene |
ENSMUSG00000033458 |
| Gene Name |
FANCD2/FANCI-associated nuclease 1 |
| Synonyms |
Mtmr15, 6030441H18Rik |
| MMRRC Submission |
039782-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1750 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
63996506-64023843 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 64022761 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Cysteine
at position 164
(Y164C)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000130012
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000032735]
[ENSMUST00000163289]
|
| AlphaFold |
Q69ZT1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000032735
|
| SMART Domains |
Protein: ENSMUSP00000032735
Gene: ENSMUSG00000030521
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Mpp10
|
20 |
654 |
6.9e-217 |
PFAM |
|
low complexity region
|
666 |
671 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000163289
AA Change: Y164C
PolyPhen 2
Score 0.140 (Sensitivity: 0.92; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000130012
Gene: ENSMUSG00000033458
AA Change: Y164C
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1ihga1
|
600 |
737 |
5e-5 |
SMART |
|
Blast:VRR_NUC
|
834 |
867 |
2e-12 |
BLAST |
|
VRR_NUC
|
896 |
1011 |
1.99e-37 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177443
AA Change: Y164C
PolyPhen 2
Score 0.140 (Sensitivity: 0.92; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000135335
Gene: ENSMUSG00000033458
AA Change: Y164C
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1ihga1
|
600 |
737 |
5e-5 |
SMART |
|
Blast:VRR_NUC
|
834 |
867 |
2e-12 |
BLAST |
|
VRR_NUC
|
896 |
1011 |
1.99e-37 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206047
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206329
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206730
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206778
|
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.9%
- 10x: 95.2%
- 20x: 91.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene plays a role in DNA interstrand cross-link repair and encodes a protein with 5' flap endonuclease and 5'-3' exonuclease activity. Mutations in this gene cause karyomegalic interstitial nephritis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Feb 2016]
PHENOTYPE: Mice homozygous for mutations in this gene display renal tubular karyomegaly with polyploidy and defects in interstrand cross-link DNA repair. Some homozygous mice also display hepatocyte karyomegaly and liver dysfunction. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 113 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933402N03Rik |
G |
T |
7: 130,747,859 (GRCm39) |
N44K |
probably benign |
Het |
| Acd |
C |
A |
8: 106,425,524 (GRCm39) |
A270S |
possibly damaging |
Het |
| Acnat1 |
G |
A |
4: 49,451,042 (GRCm39) |
T23I |
probably benign |
Het |
| Adam26a |
T |
G |
8: 44,023,226 (GRCm39) |
E88A |
possibly damaging |
Het |
| Adgrb1 |
G |
A |
15: 74,413,676 (GRCm39) |
V589M |
probably benign |
Het |
| Agbl2 |
T |
A |
2: 90,646,720 (GRCm39) |
|
probably benign |
Het |
| Aif1 |
G |
A |
17: 35,391,127 (GRCm39) |
P44L |
probably benign |
Het |
| Amh |
AGCGCCTTGG |
AG |
10: 80,641,419 (GRCm39) |
|
probably null |
Het |
| Asap2 |
T |
C |
12: 21,253,999 (GRCm39) |
L170P |
probably damaging |
Het |
| Btg2 |
T |
C |
1: 134,006,769 (GRCm39) |
D8G |
probably benign |
Het |
| Cacna1g |
A |
T |
11: 94,334,118 (GRCm39) |
V841E |
probably damaging |
Het |
| Cacna2d1 |
C |
T |
5: 16,469,286 (GRCm39) |
P230L |
probably benign |
Het |
| Cacna2d2 |
A |
T |
9: 107,401,843 (GRCm39) |
D766V |
probably damaging |
Het |
| Carns1 |
A |
G |
19: 4,223,156 (GRCm39) |
W23R |
possibly damaging |
Het |
| Cdk11b |
T |
A |
4: 155,713,137 (GRCm39) |
|
probably null |
Het |
| Chrna3 |
T |
C |
9: 54,923,341 (GRCm39) |
S156G |
probably damaging |
Het |
| Cmya5 |
A |
T |
13: 93,232,171 (GRCm39) |
N972K |
probably benign |
Het |
| Cpne7 |
C |
A |
8: 123,861,263 (GRCm39) |
P541T |
probably damaging |
Het |
| Cracd |
A |
G |
5: 77,005,522 (GRCm39) |
I628V |
unknown |
Het |
| Csmd1 |
A |
T |
8: 15,967,303 (GRCm39) |
L3187I |
probably damaging |
Het |
| Dbt |
A |
G |
3: 116,339,943 (GRCm39) |
I404V |
probably benign |
Het |
| Dgki |
A |
T |
6: 36,893,369 (GRCm39) |
I819K |
probably damaging |
Het |
| Dip2b |
T |
A |
15: 100,076,347 (GRCm39) |
S782T |
probably benign |
Het |
| Dlc1 |
A |
T |
8: 37,325,244 (GRCm39) |
|
probably null |
Het |
| Dnajc13 |
A |
T |
9: 104,098,676 (GRCm39) |
V459E |
probably damaging |
Het |
| Enam |
A |
G |
5: 88,651,086 (GRCm39) |
E790G |
probably damaging |
Het |
| Epb41l4a |
G |
C |
18: 33,961,261 (GRCm39) |
Y424* |
probably null |
Het |
| Extl1 |
A |
G |
4: 134,089,999 (GRCm39) |
S370P |
probably benign |
Het |
| Fbxw15 |
G |
A |
9: 109,387,314 (GRCm39) |
S227F |
probably damaging |
Het |
| Fbxw25 |
A |
T |
9: 109,479,141 (GRCm39) |
I370N |
probably benign |
Het |
| Fcgbp |
T |
A |
7: 27,792,868 (GRCm39) |
Y957* |
probably null |
Het |
| Gkap1 |
C |
A |
13: 58,384,857 (GRCm39) |
E77* |
probably null |
Het |
| Gkn1 |
A |
T |
6: 87,326,105 (GRCm39) |
N28K |
unknown |
Het |
| Gls2 |
A |
G |
10: 128,037,194 (GRCm39) |
E245G |
probably damaging |
Het |
| Glyat |
G |
A |
19: 12,623,679 (GRCm39) |
V32I |
probably benign |
Het |
| Gm2431 |
A |
T |
7: 141,811,762 (GRCm39) |
C47* |
probably null |
Het |
| Gm5431 |
T |
C |
11: 48,785,658 (GRCm39) |
D239G |
probably benign |
Het |
| Ift70a1 |
C |
T |
2: 75,810,599 (GRCm39) |
V495I |
probably benign |
Het |
| Inpp5d |
T |
C |
1: 87,626,803 (GRCm39) |
F540L |
probably damaging |
Het |
| Kcna1 |
A |
C |
6: 126,619,771 (GRCm39) |
I183S |
probably benign |
Het |
| Kpna2 |
G |
T |
11: 106,882,271 (GRCm39) |
L212I |
probably damaging |
Het |
| Krt36 |
C |
G |
11: 99,994,884 (GRCm39) |
R229S |
probably benign |
Het |
| Krt78 |
G |
A |
15: 101,854,812 (GRCm39) |
H1000Y |
probably benign |
Het |
| Krt90 |
A |
G |
15: 101,461,800 (GRCm39) |
|
probably benign |
Het |
| Ldlrad4 |
C |
A |
18: 68,239,758 (GRCm39) |
F59L |
probably benign |
Het |
| Lrrc3b |
T |
C |
14: 15,358,601 (GRCm38) |
N2D |
probably benign |
Het |
| Madd |
T |
C |
2: 90,998,236 (GRCm39) |
D239G |
probably damaging |
Het |
| Mapk8ip3 |
C |
T |
17: 25,133,433 (GRCm39) |
G332S |
probably null |
Het |
| Mastl |
A |
T |
2: 23,036,093 (GRCm39) |
L141* |
probably null |
Het |
| Mdh1b |
T |
C |
1: 63,758,681 (GRCm39) |
N304D |
probably benign |
Het |
| Mfsd4b3-ps |
G |
T |
10: 39,823,929 (GRCm39) |
N110K |
probably benign |
Het |
| Mtus2 |
T |
C |
5: 148,214,443 (GRCm39) |
S1035P |
probably damaging |
Het |
| Muc21 |
T |
A |
17: 35,931,940 (GRCm39) |
|
probably benign |
Het |
| Myh11 |
T |
A |
16: 14,018,622 (GRCm39) |
D1908V |
probably damaging |
Het |
| Myh11 |
T |
C |
16: 14,033,654 (GRCm39) |
E1080G |
probably damaging |
Het |
| Mypn |
A |
C |
10: 62,971,976 (GRCm39) |
M688R |
probably benign |
Het |
| Nat8l |
G |
T |
5: 34,158,130 (GRCm39) |
C180F |
probably damaging |
Het |
| Nip7 |
T |
A |
8: 107,784,018 (GRCm39) |
L86Q |
probably damaging |
Het |
| Nisch |
C |
T |
14: 30,896,839 (GRCm39) |
|
probably benign |
Het |
| Nop2 |
A |
G |
6: 125,114,601 (GRCm39) |
I283V |
probably benign |
Het |
| Oas1h |
T |
A |
5: 121,009,840 (GRCm39) |
|
probably null |
Het |
| Or10ag56 |
T |
C |
2: 87,139,196 (GRCm39) |
V41A |
probably benign |
Het |
| Or2g25 |
A |
C |
17: 37,970,564 (GRCm39) |
I220S |
probably damaging |
Het |
| Or4c101 |
C |
A |
2: 88,390,402 (GRCm39) |
D185E |
possibly damaging |
Het |
| Or4c104 |
T |
C |
2: 88,586,117 (GRCm39) |
R301G |
probably benign |
Het |
| Or56b1b |
A |
T |
7: 108,164,564 (GRCm39) |
L146* |
probably null |
Het |
| Or5w17 |
T |
A |
2: 87,583,530 (GRCm39) |
D269V |
probably damaging |
Het |
| Or8b42 |
T |
A |
9: 38,341,986 (GRCm39) |
M136K |
probably damaging |
Het |
| P4hb |
A |
G |
11: 120,453,546 (GRCm39) |
V373A |
probably damaging |
Het |
| Pappa2 |
C |
A |
1: 158,590,720 (GRCm39) |
E1645* |
probably null |
Het |
| Pcdh10 |
G |
T |
3: 45,336,316 (GRCm39) |
E877* |
probably null |
Het |
| Pcdhb17 |
C |
T |
18: 37,618,764 (GRCm39) |
R185C |
probably damaging |
Het |
| Pcdhb17 |
A |
G |
18: 37,620,070 (GRCm39) |
H620R |
possibly damaging |
Het |
| Pdcl3 |
T |
A |
1: 39,034,946 (GRCm39) |
F168I |
probably damaging |
Het |
| Pde4a |
T |
A |
9: 21,114,528 (GRCm39) |
I365N |
probably damaging |
Het |
| Pdzd2 |
A |
G |
15: 12,385,950 (GRCm39) |
V940A |
probably damaging |
Het |
| Picalm |
T |
A |
7: 89,840,390 (GRCm39) |
S399T |
possibly damaging |
Het |
| Pigk |
A |
T |
3: 152,450,101 (GRCm39) |
I249F |
probably damaging |
Het |
| Plxnb1 |
C |
A |
9: 108,940,836 (GRCm39) |
H1570Q |
probably benign |
Het |
| Plxnc1 |
A |
G |
10: 94,635,359 (GRCm39) |
Y1321H |
probably damaging |
Het |
| Ppm1g |
G |
A |
5: 31,363,560 (GRCm39) |
S114F |
probably damaging |
Het |
| Rassf4 |
A |
G |
6: 116,617,228 (GRCm39) |
M259T |
probably damaging |
Het |
| Rbm47 |
T |
C |
5: 66,176,653 (GRCm39) |
K557E |
possibly damaging |
Het |
| Rhobtb1 |
A |
G |
10: 69,115,236 (GRCm39) |
K21R |
probably damaging |
Het |
| Selenoi |
T |
C |
5: 30,462,771 (GRCm39) |
F212S |
probably benign |
Het |
| Shc3 |
T |
G |
13: 51,603,328 (GRCm39) |
Y259S |
probably damaging |
Het |
| Skic3 |
T |
A |
13: 76,288,720 (GRCm39) |
L951Q |
possibly damaging |
Het |
| Slc11a2 |
T |
C |
15: 100,299,168 (GRCm39) |
N134S |
probably damaging |
Het |
| Slc9a7 |
A |
T |
X: 20,028,717 (GRCm39) |
M368K |
probably damaging |
Het |
| Slx4ip |
T |
A |
2: 136,888,669 (GRCm39) |
C117S |
probably damaging |
Het |
| Spata31d1d |
T |
A |
13: 59,876,509 (GRCm39) |
Q342L |
probably benign |
Het |
| Spink13 |
T |
A |
18: 62,740,820 (GRCm39) |
Y93F |
probably damaging |
Het |
| St6galnac5 |
A |
T |
3: 152,551,958 (GRCm39) |
I203N |
possibly damaging |
Het |
| Syne2 |
T |
A |
12: 76,099,579 (GRCm39) |
C5335S |
probably damaging |
Het |
| Tagap |
T |
A |
17: 8,148,742 (GRCm39) |
D173E |
probably benign |
Het |
| Tekt3 |
A |
C |
11: 62,960,867 (GRCm39) |
Y12S |
probably damaging |
Het |
| Tmem81 |
T |
A |
1: 132,435,321 (GRCm39) |
N42K |
probably damaging |
Het |
| Tnc |
A |
G |
4: 63,890,972 (GRCm39) |
W1728R |
probably damaging |
Het |
| Ttc33 |
C |
T |
15: 5,241,579 (GRCm39) |
R135* |
probably null |
Het |
| Unc5c |
A |
G |
3: 141,533,278 (GRCm39) |
D842G |
possibly damaging |
Het |
| Usp43 |
A |
T |
11: 67,770,779 (GRCm39) |
H618Q |
probably damaging |
Het |
| Vmn2r50 |
T |
G |
7: 9,786,915 (GRCm39) |
N64T |
possibly damaging |
Het |
| Vmn2r53 |
T |
C |
7: 12,315,632 (GRCm39) |
Y729C |
probably damaging |
Het |
| Vmn2r59 |
T |
A |
7: 41,695,251 (GRCm39) |
H387L |
possibly damaging |
Het |
| Vstm2a |
G |
T |
11: 16,213,166 (GRCm39) |
V184F |
possibly damaging |
Het |
| Wdr53 |
T |
G |
16: 32,070,935 (GRCm39) |
N93K |
probably damaging |
Het |
| Wdr95 |
A |
G |
5: 149,505,351 (GRCm39) |
|
probably null |
Het |
| Xpot |
A |
T |
10: 121,438,932 (GRCm39) |
|
probably null |
Het |
| Xrcc5 |
C |
T |
1: 72,364,246 (GRCm39) |
Q233* |
probably null |
Het |
| Zbtb18 |
T |
A |
1: 177,275,077 (GRCm39) |
C137S |
possibly damaging |
Het |
| Zfp58 |
C |
A |
13: 67,639,598 (GRCm39) |
G298* |
probably null |
Het |
| Zfp963 |
A |
G |
8: 70,196,100 (GRCm39) |
S118P |
possibly damaging |
Het |
| Zmynd15 |
A |
T |
11: 70,353,393 (GRCm39) |
Q336L |
probably benign |
Het |
|
| Other mutations in Fan1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01648:Fan1
|
APN |
7 |
64,022,297 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01752:Fan1
|
APN |
7 |
64,022,542 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01971:Fan1
|
APN |
7 |
64,003,459 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02043:Fan1
|
APN |
7 |
64,021,367 (GRCm39) |
splice site |
probably null |
|
|
IGL02542:Fan1
|
APN |
7 |
64,014,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02731:Fan1
|
APN |
7 |
64,022,741 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL03111:Fan1
|
APN |
7 |
63,999,816 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
hitched
|
UTSW |
7 |
64,014,377 (GRCm39) |
missense |
probably damaging |
1.00 |
|
stitched
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0270:Fan1
|
UTSW |
7 |
63,998,619 (GRCm39) |
missense |
probably benign |
0.26 |
|
R0632:Fan1
|
UTSW |
7 |
64,012,947 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1714:Fan1
|
UTSW |
7 |
64,016,435 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1822:Fan1
|
UTSW |
7 |
64,022,554 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2031:Fan1
|
UTSW |
7 |
64,004,172 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2107:Fan1
|
UTSW |
7 |
64,016,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2126:Fan1
|
UTSW |
7 |
63,996,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2869:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2869:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2870:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2870:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2871:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2871:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2873:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3849:Fan1
|
UTSW |
7 |
64,022,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3850:Fan1
|
UTSW |
7 |
64,022,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3949:Fan1
|
UTSW |
7 |
64,021,292 (GRCm39) |
nonsense |
probably null |
|
|
R4007:Fan1
|
UTSW |
7 |
64,016,309 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4490:Fan1
|
UTSW |
7 |
64,018,928 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4623:Fan1
|
UTSW |
7 |
64,023,301 (GRCm39) |
nonsense |
probably null |
|
|
R4918:Fan1
|
UTSW |
7 |
64,023,286 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R5328:Fan1
|
UTSW |
7 |
64,004,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5691:Fan1
|
UTSW |
7 |
64,004,118 (GRCm39) |
splice site |
probably null |
|
|
R5902:Fan1
|
UTSW |
7 |
64,023,070 (GRCm39) |
splice site |
probably null |
|
|
R5905:Fan1
|
UTSW |
7 |
64,003,399 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6126:Fan1
|
UTSW |
7 |
64,014,318 (GRCm39) |
nonsense |
probably null |
|
|
R6195:Fan1
|
UTSW |
7 |
64,004,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6233:Fan1
|
UTSW |
7 |
64,004,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6405:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6434:Fan1
|
UTSW |
7 |
64,004,129 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6460:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6469:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6471:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6473:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6696:Fan1
|
UTSW |
7 |
63,999,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6708:Fan1
|
UTSW |
7 |
64,022,554 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6713:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6714:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6749:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6841:Fan1
|
UTSW |
7 |
64,014,377 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6858:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6859:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6860:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6925:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6927:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6936:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6938:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6939:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7040:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7120:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7290:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7292:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7459:Fan1
|
UTSW |
7 |
63,998,714 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7460:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7464:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7465:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7465:Fan1
|
UTSW |
7 |
64,003,386 (GRCm39) |
missense |
probably benign |
0.30 |
|
R7608:Fan1
|
UTSW |
7 |
64,003,979 (GRCm39) |
splice site |
probably null |
|
|
R7624:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7629:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7682:Fan1
|
UTSW |
7 |
64,022,512 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7731:Fan1
|
UTSW |
7 |
64,022,444 (GRCm39) |
missense |
probably benign |
0.17 |
|
R7863:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8054:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8055:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8057:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8058:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8101:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8241:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8262:Fan1
|
UTSW |
7 |
64,023,054 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8274:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8275:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8276:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8285:Fan1
|
UTSW |
7 |
64,016,348 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8318:Fan1
|
UTSW |
7 |
63,999,803 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8402:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8466:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8468:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8799:Fan1
|
UTSW |
7 |
64,016,406 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8821:Fan1
|
UTSW |
7 |
64,004,249 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9030:Fan1
|
UTSW |
7 |
64,022,761 (GRCm39) |
missense |
probably benign |
0.14 |
|
R9181:Fan1
|
UTSW |
7 |
64,016,400 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9525:Fan1
|
UTSW |
7 |
64,022,007 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9564:Fan1
|
UTSW |
7 |
63,999,240 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9565:Fan1
|
UTSW |
7 |
63,999,240 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9796:Fan1
|
UTSW |
7 |
64,022,278 (GRCm39) |
missense |
probably benign |
0.09 |
|
X0025:Fan1
|
UTSW |
7 |
64,022,583 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCGGAGAGGATTTCGTGTTACTGAC -3'
(R):5'- GGTATGACCTCATTCGGCACCTTG -3'
Sequencing Primer
(F):5'- TTACTGACGAGAGTTGAATCTGAG -3'
(R):5'- TTCAAGTAGAGCCTGCTCAG -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation