Mutagenetix > Incidental Mutation

Incidental Mutation 'R1746:Igfn1'

193957

Institutional Source

Beutler Lab

Gene Symbol

Igfn1

Ensembl Gene

ENSMUSG00000051985

Gene Name

immunoglobulin-like and fibronectin type III domain containing 1

Synonyms

9830123M21Rik

MMRRC Submission

039778-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.076) question?

Stock #

R1746 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

135881316-135934080 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 135897561 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Proline at position 1002 (S1002P)

Ref Sequence

ENSEMBL: ENSMUSP00000129680 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000166193]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000124134

SMART Domains

Protein: ENSMUSP00000119230
Gene: ENSMUSG00000051985

Domain	Start	End	E-Value	Type
IG	73	159	1.29e-6	SMART
IG_like	258	344	5.45e1	SMART
IG	354	435	1.79e0	SMART
IG	445	524	3.54e-4	SMART
IG	538	624	4.86e-2	SMART
FN3	627	711	3.99e-10	SMART
FN3	727	810	9.1e-14	SMART
FN3	828	911	1.5e-14	SMART
IG	938	1021	6.41e-2	SMART
FN3	1024	1106	3.2e-9	SMART
IGc2	1152	1219	4.89e-7	SMART

Predicted Effect

possibly damaging
Transcript: ENSMUST00000166193
AA Change: S1002P

PolyPhen 2 Score 0.876 (Sensitivity: 0.83; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000129680
Gene: ENSMUSG00000051985
AA Change: S1002P

Domain	Start	End	E-Value	Type
low complexity region	90	101	N/A	INTRINSIC
IG	193	279	1.29e-6	SMART
PDB:2LHU\|A	302	365	8e-7	PDB
IG_like	378	464	5.45e1	SMART
IG	474	555	1.79e0	SMART
low complexity region	724	739	N/A	INTRINSIC
internal_repeat_2	838	1006	9.98e-5	PROSPERO
low complexity region	1067	1084	N/A	INTRINSIC
internal_repeat_2	1812	1967	9.98e-5	PROSPERO
Pfam:I-set	2054	2139	6.2e-8	PFAM
IG	2153	2239	4.86e-2	SMART
FN3	2242	2326	3.99e-10	SMART
FN3	2342	2425	9.1e-14	SMART
FN3	2443	2526	1.5e-14	SMART
IG	2553	2636	6.41e-2	SMART
FN3	2639	2721	3.2e-9	SMART
IGc2	2767	2834	4.89e-7	SMART

Meta Mutation Damage Score

0.1795

Coding Region Coverage

1x: 97.4%
3x: 96.9%
10x: 95.3%
20x: 92.6%

Validation Efficiency

100% (62/62)

Allele List at MGI

Other mutations in this stock

Total: 60 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adamts16	T	A	13: 70,927,717 (GRCm39)		probably null	Het
Agrp	G	T	8: 106,293,467 (GRCm39)	T106K	probably damaging	Het
Aknad1	A	G	3: 108,659,099 (GRCm39)	T38A	possibly damaging	Het
Anpep	C	T	7: 79,488,004 (GRCm39)	E518K	probably benign	Het
Arhgap21	T	C	2: 20,865,910 (GRCm39)	E902G	probably damaging	Het
Atg2b	A	G	12: 105,635,588 (GRCm39)	S227P	possibly damaging	Het
Atp2c2	C	T	8: 120,461,182 (GRCm39)		probably benign	Het
Atxn10	T	C	15: 85,260,864 (GRCm39)	V203A	probably damaging	Het
Chd9	A	C	8: 91,737,326 (GRCm39)	E1468D	probably benign	Het
Cntn5	T	A	9: 9,831,577 (GRCm39)	D601V	probably damaging	Het
Col4a2	G	A	8: 11,496,020 (GRCm39)	G1547D	probably benign	Het
Cul1	A	G	6: 47,485,179 (GRCm39)	E270G	probably damaging	Het
Dclk2	C	T	3: 86,712,946 (GRCm39)	R503Q	possibly damaging	Het
Dmgdh	C	A	13: 93,888,933 (GRCm39)	T857K	probably benign	Het
Ednra	T	G	8: 78,398,211 (GRCm39)	T279P	probably benign	Het
Erbin	A	G	13: 103,987,339 (GRCm39)	I407T	probably damaging	Het
Fggy	A	G	4: 95,814,965 (GRCm39)	Y440C	probably damaging	Het
Flrt2	A	T	12: 95,747,566 (GRCm39)	N635Y	possibly damaging	Het
Fnbp1l	A	G	3: 122,350,140 (GRCm39)	I357T	probably benign	Het
Gulp1	A	G	1: 44,793,513 (GRCm39)	H58R	possibly damaging	Het
Hid1	A	T	11: 115,245,464 (GRCm39)	V446E	probably damaging	Het
Klri1	A	G	6: 129,675,118 (GRCm39)		probably null	Het
Kmt2d	A	C	15: 98,762,259 (GRCm39)	L409R	probably damaging	Het
Ltn1	A	C	16: 87,208,669 (GRCm39)	S810A	possibly damaging	Het
Mysm1	G	A	4: 94,836,648 (GRCm39)	Q721*	probably null	Het
Nae1	A	G	8: 105,254,017 (GRCm39)	V105A	possibly damaging	Het
Nagpa	C	T	16: 5,021,503 (GRCm39)	V83M	probably damaging	Het
Nrg2	G	A	18: 36,154,975 (GRCm39)	T503M	probably damaging	Het
Nrxn3	A	G	12: 89,221,789 (GRCm39)	M150V	possibly damaging	Het
Or5p52	C	A	7: 107,502,093 (GRCm39)	H56Q	probably benign	Het
Or8g28	A	G	9: 39,169,498 (GRCm39)	S157P	probably damaging	Het
Papola	T	A	12: 105,773,468 (GRCm39)	D162E	probably benign	Het
Plxnc1	T	C	10: 94,680,041 (GRCm39)		probably null	Het
Ppp1r16b	T	A	2: 158,588,585 (GRCm39)		probably null	Het
Ptprq	T	A	10: 107,474,691 (GRCm39)	E1338V	probably damaging	Het
Puf60	G	A	15: 75,942,633 (GRCm39)	H437Y	probably benign	Het
Qsox2	C	T	2: 26,110,650 (GRCm39)	V189I	probably benign	Het
Rad51ap2	A	T	12: 11,507,776 (GRCm39)	D566V	probably benign	Het
Rb1cc1	T	A	1: 6,333,237 (GRCm39)		probably null	Het
Rfpl4b	C	T	10: 38,697,049 (GRCm39)	C184Y	possibly damaging	Het
Rif1	GCCACCA	GCCA	2: 52,000,336 (GRCm39)		probably benign	Het
Rundc3a	GAGCC	GAGCCAGCC	11: 102,291,739 (GRCm39)		probably null	Het
Scara5	A	C	14: 65,968,539 (GRCm39)	M271L	probably benign	Het
Sel1l2	A	G	2: 140,127,157 (GRCm39)	L118P	probably damaging	Het
Sema6a	T	A	18: 47,439,416 (GRCm39)		probably benign	Het
Siglech	T	A	7: 55,418,252 (GRCm39)	H73Q	probably benign	Het
Sim1	A	G	10: 50,860,205 (GRCm39)	D689G	probably benign	Het
Skp2	T	C	15: 9,139,530 (GRCm39)	E55G	possibly damaging	Het
Slc1a1	T	A	19: 28,871,869 (GRCm39)	V114E	probably benign	Het
Slc26a6	G	A	9: 108,738,916 (GRCm39)	G614D	probably benign	Het
Sptbn2	C	T	19: 4,795,992 (GRCm39)	Q1724*	probably null	Het
Tet3	T	C	6: 83,345,050 (GRCm39)	T1796A	probably damaging	Het
Tmem117	A	C	15: 94,829,714 (GRCm39)	D183A	possibly damaging	Het
Trmt44	A	G	5: 35,721,403 (GRCm39)	S587P	probably benign	Het
Ttn	G	T	2: 76,619,166 (GRCm39)		probably benign	Het
Tubgcp5	G	A	7: 55,458,285 (GRCm39)	V399M	probably benign	Het
Txndc2	T	A	17: 65,945,130 (GRCm39)	D349V	probably damaging	Het
Uggt2	T	A	14: 119,250,915 (GRCm39)	N1194I	probably benign	Het
Vmn1r178	A	T	7: 23,593,329 (GRCm39)	I53L	probably benign	Het
Vmn2r129	G	T	4: 156,686,692 (GRCm39)		noncoding transcript	Het

Other mutations in Igfn1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00753:Igfn1	APN	1	135,894,464 (GRCm39)	missense	probably damaging	1.00
IGL02299:Igfn1	APN	1	135,881,755 (GRCm39)	utr 3 prime	probably benign
Bounty	UTSW	1	135,904,655 (GRCm39)	critical splice donor site	probably null
R2276_Igfn1_773	UTSW	1	135,892,479 (GRCm39)	missense	probably damaging	0.98
R4058_Igfn1_315	UTSW	1	135,897,494 (GRCm39)	missense	probably benign	0.07
R0144:Igfn1	UTSW	1	135,889,751 (GRCm39)	missense	probably damaging	0.99
R0190:Igfn1	UTSW	1	135,889,790 (GRCm39)	missense	probably damaging	1.00
R0350:Igfn1	UTSW	1	135,884,505 (GRCm39)	nonsense	probably null
R0413:Igfn1	UTSW	1	135,895,334 (GRCm39)	missense	probably benign	0.23
R0504:Igfn1	UTSW	1	135,896,267 (GRCm39)	missense	probably benign	0.00
R0606:Igfn1	UTSW	1	135,887,639 (GRCm39)	missense	probably damaging	1.00
R0681:Igfn1	UTSW	1	135,891,591 (GRCm39)	missense	possibly damaging	0.88
R0825:Igfn1	UTSW	1	135,890,864 (GRCm39)	missense	probably damaging	1.00
R0839:Igfn1	UTSW	1	135,882,418 (GRCm39)	missense	probably damaging	1.00
R1066:Igfn1	UTSW	1	135,898,463 (GRCm39)	missense	probably benign
R1078:Igfn1	UTSW	1	135,902,585 (GRCm39)	missense	probably damaging	1.00
R1224:Igfn1	UTSW	1	135,897,494 (GRCm39)	missense	probably benign	0.07
R1569:Igfn1	UTSW	1	135,896,771 (GRCm39)	missense	probably benign
R1626:Igfn1	UTSW	1	135,896,705 (GRCm39)	missense	probably benign	0.29
R1663:Igfn1	UTSW	1	135,896,046 (GRCm39)	missense	probably benign	0.15
R1677:Igfn1	UTSW	1	135,898,839 (GRCm39)	missense	probably damaging	0.99
R1709:Igfn1	UTSW	1	135,883,311 (GRCm39)	missense	probably benign	0.24
R1728:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1728:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1728:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1728:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1728:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1728:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1728:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1728:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1729:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1729:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1729:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1729:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1729:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1729:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1729:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1729:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1730:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1730:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1739:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1739:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1739:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1739:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1739:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1739:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1739:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1739:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1762:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1762:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1762:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1762:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1762:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1762:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1762:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1762:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1783:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1783:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1783:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1783:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1783:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1783:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1783:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1783:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1784:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1784:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1785:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1785:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1785:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1785:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1785:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1785:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1785:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1785:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1847:Igfn1	UTSW	1	135,897,126 (GRCm39)	missense	probably benign
R1866:Igfn1	UTSW	1	135,902,606 (GRCm39)	splice site	probably null
R1921:Igfn1	UTSW	1	135,893,801 (GRCm39)	critical splice donor site	probably null
R1984:Igfn1	UTSW	1	135,889,782 (GRCm39)	missense	probably benign	0.39
R2049:Igfn1	UTSW	1	135,902,590 (GRCm39)	splice site	probably benign
R2049:Igfn1	UTSW	1	135,898,376 (GRCm39)	missense	probably benign
R2098:Igfn1	UTSW	1	135,906,043 (GRCm39)	missense	probably damaging	1.00
R2130:Igfn1	UTSW	1	135,902,590 (GRCm39)	splice site	probably benign
R2141:Igfn1	UTSW	1	135,902,590 (GRCm39)	splice site	probably benign
R2276:Igfn1	UTSW	1	135,892,479 (GRCm39)	missense	probably damaging	0.98
R2425:Igfn1	UTSW	1	135,890,840 (GRCm39)	missense	probably damaging	1.00
R2483:Igfn1	UTSW	1	135,897,275 (GRCm39)	missense	probably benign
R2504:Igfn1	UTSW	1	135,897,054 (GRCm39)	missense	probably benign	0.07
R3109:Igfn1	UTSW	1	135,925,586 (GRCm39)	missense	probably benign	0.12
R3421:Igfn1	UTSW	1	135,904,655 (GRCm39)	critical splice donor site	probably null
R3423:Igfn1	UTSW	1	135,926,379 (GRCm39)	missense	probably benign	0.01
R3705:Igfn1	UTSW	1	135,896,147 (GRCm39)	missense	probably benign
R3871:Igfn1	UTSW	1	135,896,574 (GRCm39)	missense	probably benign	0.03
R3875:Igfn1	UTSW	1	135,882,352 (GRCm39)	missense	probably damaging	1.00
R3953:Igfn1	UTSW	1	135,894,918 (GRCm39)	missense	possibly damaging	0.61
R3955:Igfn1	UTSW	1	135,894,918 (GRCm39)	missense	possibly damaging	0.61
R3957:Igfn1	UTSW	1	135,894,918 (GRCm39)	missense	possibly damaging	0.61
R3965:Igfn1	UTSW	1	135,895,557 (GRCm39)	missense	probably benign
R4006:Igfn1	UTSW	1	135,910,100 (GRCm39)	splice site	probably null
R4058:Igfn1	UTSW	1	135,897,494 (GRCm39)	missense	probably benign	0.07
R4059:Igfn1	UTSW	1	135,897,494 (GRCm39)	missense	probably benign	0.07
R4370:Igfn1	UTSW	1	135,895,844 (GRCm39)	missense	probably benign	0.00
R4380:Igfn1	UTSW	1	135,895,509 (GRCm39)	missense	probably benign	0.00
R4495:Igfn1	UTSW	1	135,897,416 (GRCm39)	missense	possibly damaging	0.79
R4628:Igfn1	UTSW	1	135,887,468 (GRCm39)	missense	possibly damaging	0.47
R4672:Igfn1	UTSW	1	135,893,107 (GRCm39)	missense	possibly damaging	0.72
R4682:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R4702:Igfn1	UTSW	1	135,894,947 (GRCm39)	missense	possibly damaging	0.71
R4744:Igfn1	UTSW	1	135,910,196 (GRCm39)	missense	probably benign	0.07
R4777:Igfn1	UTSW	1	135,882,600 (GRCm39)	missense	probably benign
R4806:Igfn1	UTSW	1	135,895,095 (GRCm39)	missense	probably benign	0.01
R4840:Igfn1	UTSW	1	135,895,778 (GRCm39)	missense	probably benign	0.00
R4894:Igfn1	UTSW	1	135,882,520 (GRCm39)	missense	probably damaging	1.00
R4998:Igfn1	UTSW	1	135,882,404 (GRCm39)	missense	probably damaging	1.00
R5092:Igfn1	UTSW	1	135,892,564 (GRCm39)	missense	probably benign
R5108:Igfn1	UTSW	1	135,910,179 (GRCm39)	missense	probably benign
R5120:Igfn1	UTSW	1	135,901,240 (GRCm39)	missense	possibly damaging	0.93
R5127:Igfn1	UTSW	1	135,887,634 (GRCm39)	missense	probably damaging	1.00
R5231:Igfn1	UTSW	1	135,894,474 (GRCm39)	missense	probably benign	0.26
R5286:Igfn1	UTSW	1	135,895,599 (GRCm39)	missense	probably benign	0.10
R5307:Igfn1	UTSW	1	135,892,676 (GRCm39)	missense	probably damaging	1.00
R5380:Igfn1	UTSW	1	135,893,825 (GRCm39)	missense	probably damaging	1.00
R5553:Igfn1	UTSW	1	135,895,622 (GRCm39)	missense	probably damaging	1.00
R5660:Igfn1	UTSW	1	135,898,152 (GRCm39)	missense	probably benign	0.01
R5779:Igfn1	UTSW	1	135,894,578 (GRCm39)	missense	probably benign	0.16
R5818:Igfn1	UTSW	1	135,893,864 (GRCm39)	missense	possibly damaging	0.72
R5832:Igfn1	UTSW	1	135,902,533 (GRCm39)	missense	probably damaging	0.96
R5933:Igfn1	UTSW	1	135,898,341 (GRCm39)	nonsense	probably null
R5966:Igfn1	UTSW	1	135,893,152 (GRCm39)	missense	probably damaging	1.00
R6116:Igfn1	UTSW	1	135,898,205 (GRCm39)	missense	probably benign	0.00
R6297:Igfn1	UTSW	1	135,892,399 (GRCm39)	critical splice donor site	probably null
R6652:Igfn1	UTSW	1	135,891,609 (GRCm39)	missense	probably damaging	1.00
R6737:Igfn1	UTSW	1	135,897,605 (GRCm39)	missense	probably benign
R6816:Igfn1	UTSW	1	135,887,466 (GRCm39)	missense	probably benign	0.02
R6886:Igfn1	UTSW	1	135,901,198 (GRCm39)	missense	probably damaging	1.00
R6888:Igfn1	UTSW	1	135,910,218 (GRCm39)	missense	probably benign	0.33
R6975:Igfn1	UTSW	1	135,896,183 (GRCm39)	missense	probably damaging	0.96
R7105:Igfn1	UTSW	1	135,911,956 (GRCm39)	missense	probably benign	0.11
R7114:Igfn1	UTSW	1	135,894,519 (GRCm39)	missense	probably benign	0.01
R7233:Igfn1	UTSW	1	135,897,873 (GRCm39)	missense	probably benign	0.41
R7276:Igfn1	UTSW	1	135,926,376 (GRCm39)	missense	possibly damaging	0.85
R7354:Igfn1	UTSW	1	135,903,770 (GRCm39)	missense	possibly damaging	0.72
R7358:Igfn1	UTSW	1	135,891,738 (GRCm39)	missense	probably damaging	1.00
R7380:Igfn1	UTSW	1	135,889,746 (GRCm39)	missense	probably damaging	1.00
R7389:Igfn1	UTSW	1	135,894,785 (GRCm39)	missense	probably benign	0.00
R7513:Igfn1	UTSW	1	135,887,705 (GRCm39)	missense	probably damaging	1.00
R7718:Igfn1	UTSW	1	135,896,774 (GRCm39)	missense	probably benign
R7769:Igfn1	UTSW	1	135,910,143 (GRCm39)	missense	possibly damaging	0.85
R7810:Igfn1	UTSW	1	135,902,527 (GRCm39)	missense	probably damaging	0.98
R7917:Igfn1	UTSW	1	135,899,706 (GRCm39)	missense	probably damaging	0.99
R7952:Igfn1	UTSW	1	135,891,693 (GRCm39)	missense	probably damaging	0.99
R8041:Igfn1	UTSW	1	135,895,797 (GRCm39)	nonsense	probably null
R8233:Igfn1	UTSW	1	135,895,782 (GRCm39)	missense	probably benign	0.00
R8354:Igfn1	UTSW	1	135,887,619 (GRCm39)	missense	possibly damaging	0.61
R8363:Igfn1	UTSW	1	135,891,625 (GRCm39)	missense	probably benign	0.01
R8428:Igfn1	UTSW	1	135,895,520 (GRCm39)	missense	probably damaging	1.00
R8731:Igfn1	UTSW	1	135,925,574 (GRCm39)	missense	probably benign	0.02
R8756:Igfn1	UTSW	1	135,895,698 (GRCm39)	missense	probably benign	0.10
R8797:Igfn1	UTSW	1	135,902,573 (GRCm39)	missense	possibly damaging	0.93
R8913:Igfn1	UTSW	1	135,891,579 (GRCm39)	missense	possibly damaging	0.90
R8927:Igfn1	UTSW	1	135,905,984 (GRCm39)	missense	probably damaging	1.00
R8928:Igfn1	UTSW	1	135,905,984 (GRCm39)	missense	probably damaging	1.00
R9087:Igfn1	UTSW	1	135,902,606 (GRCm39)	splice site	probably null
R9109:Igfn1	UTSW	1	135,926,327 (GRCm39)	missense	probably benign	0.26
R9113:Igfn1	UTSW	1	135,883,328 (GRCm39)	missense	probably damaging	1.00
R9117:Igfn1	UTSW	1	135,902,528 (GRCm39)	missense	probably benign	0.03
R9205:Igfn1	UTSW	1	135,903,695 (GRCm39)	missense	probably damaging	0.96
R9251:Igfn1	UTSW	1	135,894,409 (GRCm39)	splice site	probably benign
R9260:Igfn1	UTSW	1	135,907,694 (GRCm39)	missense	probably benign	0.45
R9275:Igfn1	UTSW	1	135,901,185 (GRCm39)	missense	probably damaging	0.96
R9277:Igfn1	UTSW	1	135,887,520 (GRCm39)	missense	probably damaging	0.98
R9278:Igfn1	UTSW	1	135,901,185 (GRCm39)	missense	probably damaging	0.96
R9287:Igfn1	UTSW	1	135,925,544 (GRCm39)	missense	probably benign	0.33
R9298:Igfn1	UTSW	1	135,926,327 (GRCm39)	missense	probably benign	0.26
R9356:Igfn1	UTSW	1	135,899,825 (GRCm39)	nonsense	probably null
R9371:Igfn1	UTSW	1	135,906,001 (GRCm39)	missense	probably damaging	1.00
R9532:Igfn1	UTSW	1	135,897,229 (GRCm39)	missense	possibly damaging	0.61
R9653:Igfn1	UTSW	1	135,883,323 (GRCm39)	nonsense	probably null
R9666:Igfn1	UTSW	1	135,897,692 (GRCm39)	missense	possibly damaging	0.65
R9741:Igfn1	UTSW	1	135,895,383 (GRCm39)	missense	probably benign	0.00
R9748:Igfn1	UTSW	1	135,926,336 (GRCm39)	missense	possibly damaging	0.89
R9796:Igfn1	UTSW	1	135,897,611 (GRCm39)	missense	probably benign	0.26
Z1176:Igfn1	UTSW	1	135,899,738 (GRCm39)	missense	probably damaging	0.99
Z1177:Igfn1	UTSW	1	135,897,305 (GRCm39)	missense	probably benign	0.26
Z1177:Igfn1	UTSW	1	135,883,547 (GRCm39)	missense	probably damaging	1.00
Z1177:Igfn1	UTSW	1	135,910,164 (GRCm39)	missense	possibly damaging	0.73

Predicted Primers

PCR Primer
(F):5'- GTGGCTCCATTCCTAGAAGCCATC -3'
(R):5'- GGTTCCAGAAGCCTCCAATTTCCTC -3'

Sequencing Primer
(F):5'- AGACTCTGCCCACTCTGGAC -3'
(R):5'- ATTTCCTCAGAGCTGGACAG -3'

Posted On

2014-05-23