Mutagenetix > Incidental Mutation

Incidental Mutation 'R1758:Dnah12'

195122

Institutional Source

Beutler Lab

Gene Symbol

Dnah12

Ensembl Gene

ENSMUSG00000021879

Gene Name

dynein, axonemal, heavy chain 12

Synonyms

HL19, DHC3, Dnahc7l, 4921531P07Rik, HL-19, LOC380889, Hdhc3, Dnahc12, DLP12

MMRRC Submission

039790-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.187) question?

Stock #

R1758 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

26414429-26613660 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to A at 26488071 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Glutamine to Lysine at position 992 (Q992K)

Ref Sequence

ENSEMBL: ENSMUSP00000022433 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000022433] [ENSMUST00000073309]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000022433
AA Change: Q992K

PolyPhen 2 Score 0.021 (Sensitivity: 0.95; Specificity: 0.80)

SMART Domains

Protein: ENSMUSP00000022433
Gene: ENSMUSG00000021879
AA Change: Q992K

Domain	Start	End	E-Value	Type
low complexity region	127	140	N/A	INTRINSIC
coiled coil region	588	666	N/A	INTRINSIC
Pfam:DHC_N2	676	1113	1.1e-147	PFAM
AAA	1268	1407	1.15e0	SMART
Pfam:AAA_5	1552	1695	1.5e-7	PFAM
Blast:AAA	1709	1827	2e-24	BLAST
Blast:AAA	1848	1898	1e-16	BLAST
AAA	1903	2051	5.42e-4	SMART
Pfam:AAA_8	2238	2316	2e-18	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000073309

SMART Domains

Protein: ENSMUSP00000073035
Gene: ENSMUSG00000021879

Domain	Start	End	E-Value	Type
Pfam:AAA_6	1	203	4e-84	PFAM

Coding Region Coverage

1x: 97.5%
3x: 97.0%
10x: 95.6%
20x: 93.2%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 95 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700029H14Rik	T	C	8: 13,612,237 (GRCm39)	R38G	possibly damaging	Het
4930590J08Rik	T	C	6: 91,892,203 (GRCm39)	V155A	possibly damaging	Het
Adgb	A	G	10: 10,302,349 (GRCm39)	S406P	probably damaging	Het
Adgrb2	C	A	4: 129,905,668 (GRCm39)	T893N	probably damaging	Het
Adgrf5	T	C	17: 43,735,484 (GRCm39)		probably null	Het
Alms1	T	A	6: 85,605,487 (GRCm39)	I2379N	probably damaging	Het
Arap3	C	T	18: 38,122,965 (GRCm39)	V512I	probably benign	Het
Atf4	C	T	15: 80,141,414 (GRCm39)	T268I	probably benign	Het
Cblif	G	A	19: 11,735,179 (GRCm39)	M266I	probably damaging	Het
Ccdc154	T	C	17: 25,382,156 (GRCm39)	L25P	probably damaging	Het
Ccdc9	G	A	7: 16,010,161 (GRCm39)	S381F	probably damaging	Het
Cdk17	C	T	10: 93,044,112 (GRCm39)	T17M	probably damaging	Het
Cep128	T	C	12: 91,314,352 (GRCm39)	N142S	probably benign	Het
Cep78	A	G	19: 15,936,900 (GRCm39)	I602T	probably damaging	Het
Clasp1	C	T	1: 118,475,755 (GRCm39)	T935I	probably damaging	Het
Cnr1	T	C	4: 33,945,000 (GRCm39)	S463P	probably damaging	Het
Cntnap1	T	A	11: 101,075,449 (GRCm39)	W876R	probably damaging	Het
Cntnap5c	A	G	17: 58,349,545 (GRCm39)	D286G	probably damaging	Het
Copa	C	T	1: 171,931,711 (GRCm39)	R321C	probably damaging	Het
Cspg4b	A	G	13: 113,505,266 (GRCm39)	T2132A	possibly damaging	Het
Ctla2a	T	G	13: 61,083,256 (GRCm39)	E98A	probably damaging	Het
Cux1	A	T	5: 136,421,176 (GRCm39)	D183E	probably damaging	Het
Cxcl15	A	C	5: 90,949,323 (GRCm39)	T163P	unknown	Het
Ddias	T	C	7: 92,508,571 (GRCm39)	N448S	probably benign	Het
Dhx8	T	C	11: 101,657,564 (GRCm39)	F1152S	probably damaging	Het
Eno3	G	T	11: 70,552,251 (GRCm39)	W301L	possibly damaging	Het
Faap100	A	T	11: 120,268,059 (GRCm39)	V238E	probably damaging	Het
Fgf4	A	G	7: 144,416,049 (GRCm39)	S137G	probably benign	Het
Fhod3	A	C	18: 25,253,367 (GRCm39)	D1439A	possibly damaging	Het
Frem2	A	G	3: 53,560,778 (GRCm39)	L1243P	probably damaging	Het
Gkn3	T	G	6: 87,365,817 (GRCm39)	M1L	probably benign	Het
Gm10250	T	C	15: 5,150,509 (GRCm39)		probably benign	Het
Gm12185	T	C	11: 48,798,859 (GRCm39)	T545A	possibly damaging	Het
Gm14226	T	A	2: 154,867,378 (GRCm39)	L445H	probably damaging	Het
Gm3404	A	T	5: 146,463,036 (GRCm39)	M73L	probably benign	Het
Gm973	G	T	1: 59,673,169 (GRCm39)	R976S	unknown	Het
Gpr146	A	T	5: 139,379,137 (GRCm39)	H313L	probably benign	Het
Gys2	T	A	6: 142,418,432 (GRCm39)	E32D	probably damaging	Het
Igsf10	G	A	3: 59,236,617 (GRCm39)	T1188I	probably benign	Het
Igsf9b	A	T	9: 27,245,548 (GRCm39)	T1172S	possibly damaging	Het
Itga8	T	A	2: 12,270,144 (GRCm39)	N114I	possibly damaging	Het
Itsn2	T	A	12: 4,708,160 (GRCm39)	V795E	possibly damaging	Het
Kdm1b	T	A	13: 47,214,244 (GRCm39)	S197T	probably benign	Het
Kif5c	G	A	2: 49,613,145 (GRCm39)	R161Q	probably benign	Het
Krt33b	T	C	11: 99,916,361 (GRCm39)	Y232C	probably damaging	Het
Lonrf2	G	A	1: 38,852,357 (GRCm39)	P165S	probably benign	Het
Lrp1	A	T	10: 127,424,453 (GRCm39)	N744K	possibly damaging	Het
Mcm10	C	A	2: 5,008,861 (GRCm39)	L369F	probably damaging	Het
Muc5ac	T	A	7: 141,355,268 (GRCm39)	I1018N	possibly damaging	Het
Myom2	T	C	8: 15,115,795 (GRCm39)	L70P	probably benign	Het
Myt1l	T	A	12: 29,877,241 (GRCm39)	N297K	unknown	Het
Ncr1	C	T	7: 4,343,807 (GRCm39)	T98I	probably benign	Het
Nek3	T	C	8: 22,650,278 (GRCm39)	E78G	probably damaging	Het
Nfatc3	T	A	8: 106,825,768 (GRCm39)	N606K	probably damaging	Het
Nup107	T	G	10: 117,597,248 (GRCm39)	D669A	probably damaging	Het
Or10ag52	A	T	2: 87,043,758 (GRCm39)	Q174L	probably benign	Het
Or10c1	A	T	17: 37,522,204 (GRCm39)	I180N	possibly damaging	Het
Or4c3	T	C	2: 89,851,673 (GRCm39)	T246A	probably benign	Het
Or8b55	A	T	9: 38,726,871 (GRCm39)	H24L	probably benign	Het
Pcnx1	T	C	12: 82,030,258 (GRCm39)	V1711A	probably benign	Het
Pik3c3	A	G	18: 30,410,063 (GRCm39)	D99G	probably damaging	Het
Pinx1	C	A	14: 64,157,024 (GRCm39)	T317K	probably benign	Het
Ppargc1b	G	T	18: 61,431,857 (GRCm39)		probably null	Het
Pradc1	T	A	6: 85,424,203 (GRCm39)	I119F	possibly damaging	Het
Psat1	G	T	19: 15,892,243 (GRCm39)	T242K	probably damaging	Het
Psma6	G	A	12: 55,454,317 (GRCm39)	C28Y	probably damaging	Het
Pyurf	A	T	6: 57,668,817 (GRCm39)	C58*	probably null	Het
Rab3gap2	C	A	1: 185,016,081 (GRCm39)	A1331E	probably benign	Het
Rnase4	T	C	14: 51,342,722 (GRCm39)	*149Q	probably null	Het
Ruvbl2	T	C	7: 45,074,586 (GRCm39)	K184R	probably benign	Het
Scn7a	T	G	2: 66,510,527 (GRCm39)	M1292L	probably benign	Het
Scn7a	A	T	2: 66,531,231 (GRCm39)	Y549N	probably damaging	Het
Selp	A	G	1: 163,959,854 (GRCm39)	D370G	possibly damaging	Het
Slc22a15	G	A	3: 101,767,769 (GRCm39)	Q386*	probably null	Het
Slc22a29	A	G	19: 8,195,126 (GRCm39)		probably null	Het
Slc26a7	A	C	4: 14,548,491 (GRCm39)	I266S	possibly damaging	Het
Smpd4	T	C	16: 17,443,872 (GRCm39)	S112P	probably damaging	Het
Smpd4	T	A	16: 17,458,744 (GRCm39)	L165Q	probably damaging	Het
Snx33	A	G	9: 56,833,982 (GRCm39)	I29T	probably benign	Het
Spen	G	A	4: 141,203,686 (GRCm39)	P1647L	unknown	Het
Strip2	T	C	6: 29,941,940 (GRCm39)		probably null	Het
Swsap1	C	T	9: 21,867,280 (GRCm39)	R75*	probably null	Het
Tesl1	A	G	X: 23,772,990 (GRCm39)	I164V	probably benign	Het
Tmem210	C	T	2: 25,178,435 (GRCm39)	T32I	probably damaging	Het
Tnn	C	T	1: 159,975,154 (GRCm39)	R91H	possibly damaging	Het
Tnni1	G	A	1: 135,736,420 (GRCm39)	R94H	probably damaging	Het
Tnrc6c	T	A	11: 117,651,556 (GRCm39)	V1693D	probably benign	Het
Trip4	G	A	9: 65,782,259 (GRCm39)	Q158*	probably null	Het
Ttc39b	T	C	4: 83,155,586 (GRCm39)	E474G	probably damaging	Het
Usp50	C	A	2: 126,617,782 (GRCm39)	C221F	probably damaging	Het
Vmn1r171	T	C	7: 23,331,781 (GRCm39)	I2T	probably benign	Het
Wdr62	T	A	7: 29,967,328 (GRCm39)	I309F	probably damaging	Het
Xdh	A	T	17: 74,217,204 (GRCm39)	V688E	probably damaging	Het
Zfyve26	A	G	12: 79,285,718 (GRCm39)	L2353P	probably damaging	Het
Zgpat	C	A	2: 181,020,633 (GRCm39)	R269S	probably damaging	Het

Other mutations in Dnah12

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01412:Dnah12	APN	14	26,492,962 (GRCm39)	missense	probably damaging	1.00
IGL01602:Dnah12	APN	14	26,431,430 (GRCm39)	splice site	probably benign
IGL01681:Dnah12	APN	14	26,443,315 (GRCm39)	missense	probably benign
IGL02082:Dnah12	APN	14	26,428,317 (GRCm39)	missense	possibly damaging	0.79
IGL02140:Dnah12	APN	14	26,437,732 (GRCm39)	missense	probably benign	0.20
IGL02170:Dnah12	APN	14	26,495,069 (GRCm39)	missense	probably damaging	0.99
IGL02174:Dnah12	APN	14	26,428,072 (GRCm39)	missense	probably benign	0.00
IGL02367:Dnah12	APN	14	26,430,316 (GRCm39)	missense	probably benign	0.30
IGL02418:Dnah12	APN	14	26,495,679 (GRCm39)	missense	probably damaging	1.00
IGL03039:Dnah12	APN	14	26,445,667 (GRCm39)	missense	probably benign	0.02
IGL03066:Dnah12	APN	14	26,418,553 (GRCm39)	missense	probably benign	0.06
drippings	UTSW	14	26,576,761 (GRCm39)	missense	probably damaging	1.00
grueben	UTSW	14	26,600,036 (GRCm39)	missense	probably damaging	1.00
BB010:Dnah12	UTSW	14	26,488,072 (GRCm39)	missense	probably benign	0.00
BB020:Dnah12	UTSW	14	26,488,072 (GRCm39)	missense	probably benign	0.00
F5770:Dnah12	UTSW	14	26,495,050 (GRCm39)	missense	possibly damaging	0.95
FR4304:Dnah12	UTSW	14	26,571,342 (GRCm39)	missense	probably damaging	1.00
FR4340:Dnah12	UTSW	14	26,571,342 (GRCm39)	missense	probably damaging	1.00
FR4342:Dnah12	UTSW	14	26,571,342 (GRCm39)	missense	probably damaging	1.00
FR4589:Dnah12	UTSW	14	26,571,342 (GRCm39)	missense	probably damaging	1.00
IGL03055:Dnah12	UTSW	14	26,594,697 (GRCm39)	missense	probably damaging	1.00
LCD18:Dnah12	UTSW	14	26,571,342 (GRCm39)	missense	probably damaging	1.00
R0003:Dnah12	UTSW	14	26,494,601 (GRCm39)	missense	probably damaging	1.00
R0110:Dnah12	UTSW	14	26,520,856 (GRCm39)	missense	probably damaging	1.00
R0302:Dnah12	UTSW	14	26,521,956 (GRCm39)	missense	probably damaging	1.00
R0355:Dnah12	UTSW	14	26,427,272 (GRCm39)	splice site	probably null
R0364:Dnah12	UTSW	14	26,445,628 (GRCm39)	missense	probably benign	0.10
R0469:Dnah12	UTSW	14	26,520,856 (GRCm39)	missense	probably damaging	1.00
R0558:Dnah12	UTSW	14	26,430,465 (GRCm39)	missense	probably benign	0.00
R0709:Dnah12	UTSW	14	26,606,222 (GRCm39)	splice site	probably benign
R0734:Dnah12	UTSW	14	26,521,970 (GRCm39)	missense	probably benign	0.00
R1273:Dnah12	UTSW	14	26,460,375 (GRCm39)	nonsense	probably null
R1496:Dnah12	UTSW	14	26,431,403 (GRCm39)	missense	probably benign
R1503:Dnah12	UTSW	14	26,495,649 (GRCm39)	missense	probably damaging	1.00
R1535:Dnah12	UTSW	14	26,538,279 (GRCm39)	missense	possibly damaging	0.91
R1608:Dnah12	UTSW	14	26,488,147 (GRCm39)	missense	probably damaging	1.00
R1682:Dnah12	UTSW	14	26,500,840 (GRCm39)	missense	possibly damaging	0.71
R1826:Dnah12	UTSW	14	26,432,174 (GRCm39)	missense	probably benign	0.01
R1829:Dnah12	UTSW	14	26,522,032 (GRCm39)	missense	probably damaging	1.00
R1829:Dnah12	UTSW	14	26,494,980 (GRCm39)	missense	probably damaging	1.00
R1862:Dnah12	UTSW	14	26,430,412 (GRCm39)	missense	probably benign	0.30
R1862:Dnah12	UTSW	14	26,418,553 (GRCm39)	missense	probably benign	0.06
R1913:Dnah12	UTSW	14	26,514,221 (GRCm39)	splice site	probably null
R1933:Dnah12	UTSW	14	26,455,650 (GRCm39)	missense	probably damaging	0.98
R2006:Dnah12	UTSW	14	26,536,416 (GRCm39)	missense	possibly damaging	0.95
R2045:Dnah12	UTSW	14	26,503,485 (GRCm39)	missense	probably null	1.00
R2113:Dnah12	UTSW	14	26,488,098 (GRCm39)	missense	probably damaging	1.00
R2125:Dnah12	UTSW	14	26,445,613 (GRCm39)	nonsense	probably null
R2126:Dnah12	UTSW	14	26,445,613 (GRCm39)	nonsense	probably null
R2207:Dnah12	UTSW	14	26,503,744 (GRCm39)	missense	probably damaging	0.99
R2213:Dnah12	UTSW	14	26,460,485 (GRCm39)	missense	probably benign	0.06
R2511:Dnah12	UTSW	14	26,491,907 (GRCm39)	missense	possibly damaging	0.65
R2875:Dnah12	UTSW	14	26,598,907 (GRCm39)	missense	probably benign	0.05
R2875:Dnah12	UTSW	14	26,414,625 (GRCm39)	missense	probably benign	0.04
R3551:Dnah12	UTSW	14	26,492,929 (GRCm39)	missense	probably benign	0.01
R3713:Dnah12	UTSW	14	26,534,747 (GRCm39)	missense	probably benign
R3729:Dnah12	UTSW	14	26,427,220 (GRCm39)	missense	probably benign	0.02
R3799:Dnah12	UTSW	14	26,492,880 (GRCm39)	missense	probably damaging	1.00
R3846:Dnah12	UTSW	14	26,431,366 (GRCm39)	missense	probably benign	0.00
R3892:Dnah12	UTSW	14	26,578,573 (GRCm39)	missense	probably benign	0.03
R3921:Dnah12	UTSW	14	26,493,008 (GRCm39)	missense	probably damaging	1.00
R3940:Dnah12	UTSW	14	26,444,754 (GRCm39)	missense	probably benign
R4065:Dnah12	UTSW	14	26,492,405 (GRCm39)	missense	probably benign	0.02
R4113:Dnah12	UTSW	14	26,414,722 (GRCm39)	missense	probably damaging	0.98
R4249:Dnah12	UTSW	14	26,430,341 (GRCm39)	missense	possibly damaging	0.70
R4259:Dnah12	UTSW	14	26,520,883 (GRCm39)	missense	probably benign	0.01
R4260:Dnah12	UTSW	14	26,520,883 (GRCm39)	missense	probably benign	0.01
R4348:Dnah12	UTSW	14	26,536,498 (GRCm39)	missense	possibly damaging	0.94
R4457:Dnah12	UTSW	14	26,537,464 (GRCm39)	missense	probably damaging	1.00
R4490:Dnah12	UTSW	14	26,455,758 (GRCm39)	missense	possibly damaging	0.67
R4491:Dnah12	UTSW	14	26,455,758 (GRCm39)	missense	possibly damaging	0.67
R4494:Dnah12	UTSW	14	26,593,812 (GRCm39)	missense	probably damaging	0.99
R4523:Dnah12	UTSW	14	26,598,915 (GRCm39)	missense	possibly damaging	0.83
R4523:Dnah12	UTSW	14	26,491,979 (GRCm39)	missense	probably damaging	0.97
R4546:Dnah12	UTSW	14	26,494,971 (GRCm39)	missense	probably damaging	1.00
R4584:Dnah12	UTSW	14	26,494,551 (GRCm39)	missense	probably damaging	1.00
R4624:Dnah12	UTSW	14	26,456,913 (GRCm39)	missense	possibly damaging	0.82
R4689:Dnah12	UTSW	14	26,427,994 (GRCm39)	missense	probably benign	0.00
R4727:Dnah12	UTSW	14	26,594,274 (GRCm39)	missense	probably damaging	1.00
R4732:Dnah12	UTSW	14	26,503,741 (GRCm39)	missense	probably damaging	1.00
R4733:Dnah12	UTSW	14	26,503,741 (GRCm39)	missense	probably damaging	1.00
R4851:Dnah12	UTSW	14	26,437,784 (GRCm39)	nonsense	probably null
R4879:Dnah12	UTSW	14	26,439,201 (GRCm39)	critical splice donor site	probably null
R4893:Dnah12	UTSW	14	26,431,325 (GRCm39)	missense	possibly damaging	0.66
R4915:Dnah12	UTSW	14	26,455,725 (GRCm39)	missense	probably damaging	1.00
R4927:Dnah12	UTSW	14	26,583,762 (GRCm39)	nonsense	probably null
R4939:Dnah12	UTSW	14	26,613,481 (GRCm39)	missense	probably damaging	1.00
R4962:Dnah12	UTSW	14	26,437,855 (GRCm39)	missense	probably benign	0.00
R5011:Dnah12	UTSW	14	26,431,326 (GRCm39)	missense	probably benign	0.03
R5013:Dnah12	UTSW	14	26,431,326 (GRCm39)	missense	probably benign	0.03
R5043:Dnah12	UTSW	14	26,606,147 (GRCm39)	missense	probably damaging	1.00
R5049:Dnah12	UTSW	14	26,456,852 (GRCm39)	missense	probably benign	0.09
R5122:Dnah12	UTSW	14	26,439,155 (GRCm39)	missense	probably benign	0.00
R5135:Dnah12	UTSW	14	26,492,434 (GRCm39)	missense	probably damaging	0.99
R5149:Dnah12	UTSW	14	26,572,883 (GRCm39)	nonsense	probably null
R5154:Dnah12	UTSW	14	26,571,320 (GRCm39)	missense	probably benign	0.12
R5206:Dnah12	UTSW	14	26,491,942 (GRCm39)	missense	probably damaging	1.00
R5307:Dnah12	UTSW	14	26,414,641 (GRCm39)	missense	possibly damaging	0.49
R5330:Dnah12	UTSW	14	26,495,787 (GRCm39)	missense	probably damaging	1.00
R5335:Dnah12	UTSW	14	26,601,695 (GRCm39)	missense	probably damaging	1.00
R5339:Dnah12	UTSW	14	26,536,494 (GRCm39)	missense	possibly damaging	0.83
R5354:Dnah12	UTSW	14	26,496,299 (GRCm39)	splice site	probably null
R5389:Dnah12	UTSW	14	26,456,904 (GRCm39)	missense	probably damaging	1.00
R5434:Dnah12	UTSW	14	26,581,256 (GRCm39)	missense	probably damaging	1.00
R5466:Dnah12	UTSW	14	26,493,007 (GRCm39)	missense	probably damaging	1.00
R5655:Dnah12	UTSW	14	26,431,424 (GRCm39)	missense	probably benign	0.01
R5681:Dnah12	UTSW	14	26,537,452 (GRCm39)	missense	probably benign	0.32
R5824:Dnah12	UTSW	14	26,492,475 (GRCm39)	critical splice donor site	probably null
R5863:Dnah12	UTSW	14	26,576,878 (GRCm39)	missense	probably damaging	1.00
R5890:Dnah12	UTSW	14	26,428,039 (GRCm39)	missense	probably benign	0.09
R5912:Dnah12	UTSW	14	26,491,965 (GRCm39)	nonsense	probably null
R5916:Dnah12	UTSW	14	26,428,073 (GRCm39)	missense	possibly damaging	0.92
R5941:Dnah12	UTSW	14	26,428,022 (GRCm39)	missense	probably benign	0.00
R5987:Dnah12	UTSW	14	26,608,828 (GRCm39)	missense	possibly damaging	0.54
R5992:Dnah12	UTSW	14	26,418,496 (GRCm39)	missense	probably benign	0.04
R6132:Dnah12	UTSW	14	26,439,066 (GRCm39)	missense	probably damaging	1.00
R6136:Dnah12	UTSW	14	26,597,227 (GRCm39)	missense	probably damaging	0.99
R6158:Dnah12	UTSW	14	26,495,642 (GRCm39)	missense	possibly damaging	0.95
R6183:Dnah12	UTSW	14	26,583,726 (GRCm39)	missense	probably damaging	1.00
R6191:Dnah12	UTSW	14	26,431,412 (GRCm39)	missense	probably benign	0.03
R6235:Dnah12	UTSW	14	26,576,761 (GRCm39)	missense	probably damaging	1.00
R6277:Dnah12	UTSW	14	26,492,439 (GRCm39)	missense	probably damaging	1.00
R6332:Dnah12	UTSW	14	26,439,129 (GRCm39)	missense	probably damaging	0.99
R6334:Dnah12	UTSW	14	26,427,989 (GRCm39)	missense	possibly damaging	0.51
R6443:Dnah12	UTSW	14	26,600,008 (GRCm39)	missense	probably benign	0.06
R6480:Dnah12	UTSW	14	26,594,412 (GRCm39)	missense	probably damaging	1.00
R6530:Dnah12	UTSW	14	26,456,865 (GRCm39)	missense	probably damaging	1.00
R6678:Dnah12	UTSW	14	26,456,847 (GRCm39)	missense	probably damaging	1.00
R6709:Dnah12	UTSW	14	26,594,706 (GRCm39)	missense	probably damaging	1.00
R6724:Dnah12	UTSW	14	26,518,180 (GRCm39)	missense	probably benign	0.02
R6745:Dnah12	UTSW	14	26,428,383 (GRCm39)	missense	probably damaging	0.99
R6788:Dnah12	UTSW	14	26,523,470 (GRCm39)	missense	probably damaging	0.99
R6894:Dnah12	UTSW	14	26,456,904 (GRCm39)	missense	probably damaging	1.00
R6912:Dnah12	UTSW	14	26,600,036 (GRCm39)	missense	probably damaging	1.00
R6982:Dnah12	UTSW	14	26,521,033 (GRCm39)	splice site	probably null
R7001:Dnah12	UTSW	14	26,601,681 (GRCm39)	missense	probably damaging	0.99
R7002:Dnah12	UTSW	14	26,598,955 (GRCm39)	missense	probably damaging	1.00
R7017:Dnah12	UTSW	14	26,456,835 (GRCm39)	missense	probably benign
R7107:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7108:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7121:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7122:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7135:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7135:Dnah12	UTSW	14	26,523,370 (GRCm39)	missense	probably damaging	0.99
R7150:Dnah12	UTSW	14	26,583,689 (GRCm39)	missense	probably damaging	0.99
R7188:Dnah12	UTSW	14	26,536,370 (GRCm39)	missense	probably benign	0.04
R7201:Dnah12	UTSW	14	26,536,579 (GRCm39)	missense	probably benign	0.08
R7202:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7204:Dnah12	UTSW	14	26,503,442 (GRCm39)	missense	probably damaging	0.99
R7204:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7205:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7206:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7219:Dnah12	UTSW	14	26,576,837 (GRCm39)	missense	probably damaging	0.99
R7337:Dnah12	UTSW	14	26,488,534 (GRCm39)	splice site	probably null
R7339:Dnah12	UTSW	14	26,594,277 (GRCm39)	missense	probably benign
R7363:Dnah12	UTSW	14	26,445,766 (GRCm39)	missense	probably benign
R7426:Dnah12	UTSW	14	26,445,781 (GRCm39)	missense	probably benign	0.01
R7472:Dnah12	UTSW	14	26,578,592 (GRCm39)	missense	probably benign	0.01
R7579:Dnah12	UTSW	14	26,492,460 (GRCm39)	missense	probably benign	0.05
R7655:Dnah12	UTSW	14	26,581,273 (GRCm39)	missense	probably benign	0.21
R7656:Dnah12	UTSW	14	26,581,273 (GRCm39)	missense	probably benign	0.21
R7694:Dnah12	UTSW	14	26,503,337 (GRCm39)	missense	probably damaging	1.00
R7730:Dnah12	UTSW	14	26,507,890 (GRCm39)	missense	probably damaging	1.00
R7837:Dnah12	UTSW	14	26,518,176 (GRCm39)	missense	probably benign	0.01
R7855:Dnah12	UTSW	14	26,551,286 (GRCm39)	missense	probably benign	0.14
R7870:Dnah12	UTSW	14	26,578,486 (GRCm39)	missense	probably benign	0.00
R7920:Dnah12	UTSW	14	26,578,499 (GRCm39)	missense	possibly damaging	0.58
R7933:Dnah12	UTSW	14	26,488,072 (GRCm39)	missense	probably benign	0.00
R7956:Dnah12	UTSW	14	26,430,427 (GRCm39)	missense	probably damaging	0.96
R8192:Dnah12	UTSW	14	26,428,036 (GRCm39)	missense	probably benign
R8263:Dnah12	UTSW	14	26,613,421 (GRCm39)	missense	noncoding transcript
R8287:Dnah12	UTSW	14	26,534,560 (GRCm39)	missense	probably benign
R8336:Dnah12	UTSW	14	26,432,220 (GRCm39)	missense	probably benign	0.01
R8362:Dnah12	UTSW	14	26,576,788 (GRCm39)	missense	probably damaging	1.00
R8392:Dnah12	UTSW	14	26,607,869 (GRCm39)	missense	probably benign
R8458:Dnah12	UTSW	14	26,548,849 (GRCm39)	critical splice acceptor site	probably null
R8481:Dnah12	UTSW	14	26,575,753 (GRCm39)	missense	probably benign	0.02
R8551:Dnah12	UTSW	14	26,496,227 (GRCm39)	missense	probably damaging	0.97
R8669:Dnah12	UTSW	14	26,552,582 (GRCm39)	splice site	probably benign
R8698:Dnah12	UTSW	14	26,428,418 (GRCm39)	missense	probably benign	0.02
R8709:Dnah12	UTSW	14	26,414,757 (GRCm39)	missense	probably benign	0.00
R8778:Dnah12	UTSW	14	26,455,718 (GRCm39)	missense	probably benign	0.29
R9049:Dnah12	UTSW	14	26,443,275 (GRCm39)	missense	probably benign	0.00
R9087:Dnah12	UTSW	14	26,546,503 (GRCm39)	missense	probably damaging	1.00
R9099:Dnah12	UTSW	14	26,492,325 (GRCm39)	missense	probably benign	0.31
R9153:Dnah12	UTSW	14	26,536,569 (GRCm39)	missense	probably damaging	1.00
R9177:Dnah12	UTSW	14	26,571,255 (GRCm39)	missense	possibly damaging	0.84
R9214:Dnah12	UTSW	14	26,445,060 (GRCm39)	missense	probably benign	0.02
R9268:Dnah12	UTSW	14	26,571,255 (GRCm39)	missense	possibly damaging	0.84
R9274:Dnah12	UTSW	14	26,537,374 (GRCm39)	missense	probably benign	0.00
R9293:Dnah12	UTSW	14	26,495,016 (GRCm39)	missense	probably benign
R9322:Dnah12	UTSW	14	26,492,934 (GRCm39)	missense	possibly damaging	0.75
R9353:Dnah12	UTSW	14	26,578,507 (GRCm39)	missense	probably damaging	1.00
R9506:Dnah12	UTSW	14	26,514,168 (GRCm39)	missense	probably benign	0.00
R9518:Dnah12	UTSW	14	26,495,713 (GRCm39)	missense	probably damaging	1.00
R9524:Dnah12	UTSW	14	26,572,494 (GRCm39)	missense	probably null	0.91
R9562:Dnah12	UTSW	14	26,597,281 (GRCm39)	missense	possibly damaging	0.58
R9565:Dnah12	UTSW	14	26,597,281 (GRCm39)	missense	possibly damaging	0.58
R9573:Dnah12	UTSW	14	26,414,619 (GRCm39)	missense	probably benign
R9581:Dnah12	UTSW	14	26,491,985 (GRCm39)	missense	probably damaging	1.00
R9689:Dnah12	UTSW	14	26,590,871 (GRCm39)	missense	probably null	1.00
R9727:Dnah12	UTSW	14	26,523,510 (GRCm39)	nonsense	probably null
V7580:Dnah12	UTSW	14	26,495,050 (GRCm39)	missense	possibly damaging	0.95
V7581:Dnah12	UTSW	14	26,495,050 (GRCm39)	missense	possibly damaging	0.95
X0018:Dnah12	UTSW	14	26,536,437 (GRCm39)	missense	probably damaging	1.00
X0027:Dnah12	UTSW	14	26,538,245 (GRCm39)	missense	probably damaging	1.00
X0065:Dnah12	UTSW	14	26,536,602 (GRCm39)	missense	possibly damaging	0.93
Z1177:Dnah12	UTSW	14	26,597,172 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- AGGGGAGGGTATATTTCACTACTGATTTCAT -3'
(R):5'- GCAATCACATCACGAATACTTCTGAGCAT -3'

Sequencing Primer
(F):5'- ATGAACTGTGTCTTTTAGGTGC -3'
(R):5'- GAATGAGCCATTTCTCTACAGCG -3'

Posted On

2014-05-23