Incidental Mutation 'R1781:Disp2'
| ID |
195259 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Disp2
|
| Ensembl Gene |
ENSMUSG00000040035 |
| Gene Name |
dispatched RND transporter family member 2 |
| Synonyms |
B230210L08Rik, DispB |
| MMRRC Submission |
039812-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.896)
|
| Stock # |
R1781 (G1)
|
| Quality Score |
223 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
118610183-118625656 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 118623042 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glycine to Aspartic acid
at position 1258
(G1258D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000037136
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000037547]
[ENSMUST00000063975]
[ENSMUST00000110843]
[ENSMUST00000110846]
|
| AlphaFold |
Q8CIP5 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000037547
AA Change: G1258D
PolyPhen 2
Score 0.959 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000037136
Gene: ENSMUSG00000040035
AA Change: G1258D
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
123 |
145 |
N/A |
INTRINSIC |
|
low complexity region
|
195 |
203 |
N/A |
INTRINSIC |
|
Pfam:MMPL
|
435 |
635 |
9.7e-8 |
PFAM |
|
Pfam:Sterol-sensing
|
458 |
611 |
9.1e-9 |
PFAM |
|
transmembrane domain
|
657 |
679 |
N/A |
INTRINSIC |
|
low complexity region
|
682 |
695 |
N/A |
INTRINSIC |
|
low complexity region
|
748 |
761 |
N/A |
INTRINSIC |
|
transmembrane domain
|
914 |
936 |
N/A |
INTRINSIC |
|
transmembrane domain
|
943 |
965 |
N/A |
INTRINSIC |
|
transmembrane domain
|
975 |
997 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1018 |
1040 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000063975
|
| SMART Domains |
Protein: ENSMUSP00000070031
Gene: ENSMUSG00000040035
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
123 |
145 |
N/A |
INTRINSIC |
|
low complexity region
|
195 |
203 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000110843
|
| SMART Domains |
Protein: ENSMUSP00000106467
Gene: ENSMUSG00000040035
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
123 |
145 |
N/A |
INTRINSIC |
|
low complexity region
|
195 |
203 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000110846
|
| SMART Domains |
Protein: ENSMUSP00000106470
Gene: ENSMUSG00000040035
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
123 |
145 |
N/A |
INTRINSIC |
|
low complexity region
|
195 |
203 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142072
|
| Meta Mutation Damage Score |
0.1893 |
| Coding Region Coverage |
- 1x: 97.3%
- 3x: 96.7%
- 10x: 94.6%
- 20x: 90.1%
|
| Validation Efficiency |
97% (88/91) |
| MGI Phenotype |
FUNCTION: The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. [provided by RefSeq, Sep 2015]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 90 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadacl2 |
A |
G |
3: 59,932,117 (GRCm39) |
K211E |
probably damaging |
Het |
| Abca13 |
T |
A |
11: 9,219,194 (GRCm39) |
L376Q |
probably damaging |
Het |
| Abca17 |
T |
C |
17: 24,486,531 (GRCm39) |
T1499A |
possibly damaging |
Het |
| Anks6 |
A |
C |
4: 47,043,639 (GRCm39) |
N363K |
possibly damaging |
Het |
| Apob |
T |
A |
12: 8,059,603 (GRCm39) |
I2695N |
possibly damaging |
Het |
| Arhgef18 |
C |
T |
8: 3,430,495 (GRCm39) |
R123W |
probably damaging |
Het |
| Atg14 |
T |
A |
14: 47,786,607 (GRCm39) |
|
probably null |
Het |
| Atg2a |
A |
T |
19: 6,306,243 (GRCm39) |
I1368F |
probably damaging |
Het |
| Btbd9 |
A |
G |
17: 30,732,567 (GRCm39) |
S373P |
probably damaging |
Het |
| Ccdc83 |
T |
C |
7: 89,899,749 (GRCm39) |
E41G |
probably damaging |
Het |
| Ccnh |
T |
C |
13: 85,354,254 (GRCm39) |
S233P |
possibly damaging |
Het |
| Cdh8 |
T |
C |
8: 99,917,094 (GRCm39) |
|
probably null |
Het |
| Cdh8 |
A |
T |
8: 100,006,290 (GRCm39) |
I99N |
probably damaging |
Het |
| Cdr2 |
G |
A |
7: 120,557,268 (GRCm39) |
P419L |
probably benign |
Het |
| Cds1 |
T |
A |
5: 101,960,416 (GRCm39) |
I289K |
possibly damaging |
Het |
| Cherp |
G |
A |
8: 73,221,615 (GRCm39) |
T394I |
probably damaging |
Het |
| Cyp4f17 |
T |
G |
17: 32,742,993 (GRCm39) |
I222S |
possibly damaging |
Het |
| Dcc |
A |
G |
18: 71,511,788 (GRCm39) |
S856P |
probably benign |
Het |
| Dcp1a |
C |
T |
14: 30,235,032 (GRCm39) |
T221I |
probably benign |
Het |
| Ddx10 |
A |
G |
9: 53,118,845 (GRCm39) |
S475P |
probably damaging |
Het |
| Dennd5b |
G |
T |
6: 148,928,896 (GRCm39) |
A759E |
probably damaging |
Het |
| Fhdc1 |
A |
T |
3: 84,356,111 (GRCm39) |
D444E |
probably damaging |
Het |
| Fhod1 |
T |
C |
8: 106,074,421 (GRCm39) |
|
probably benign |
Het |
| Gcnt7 |
T |
C |
2: 172,296,800 (GRCm39) |
K8R |
probably benign |
Het |
| Gk5 |
C |
T |
9: 96,015,508 (GRCm39) |
T108I |
possibly damaging |
Het |
| Gm8214 |
C |
A |
1: 183,414,129 (GRCm39) |
|
noncoding transcript |
Het |
| Gnl1 |
A |
T |
17: 36,298,638 (GRCm39) |
I434F |
probably damaging |
Het |
| Golga2 |
T |
C |
2: 32,196,588 (GRCm39) |
Y986H |
probably damaging |
Het |
| Gpr21 |
T |
C |
2: 37,407,550 (GRCm39) |
V32A |
probably benign |
Het |
| Grb14 |
A |
T |
2: 64,805,899 (GRCm39) |
|
probably null |
Het |
| H6pd |
A |
T |
4: 150,080,388 (GRCm39) |
F144L |
probably damaging |
Het |
| Hunk |
A |
G |
16: 90,229,448 (GRCm39) |
Y27C |
probably damaging |
Het |
| Ints7 |
C |
T |
1: 191,328,396 (GRCm39) |
T223M |
possibly damaging |
Het |
| Kcnmb2 |
T |
C |
3: 32,233,152 (GRCm39) |
|
probably null |
Het |
| Lilra6 |
A |
T |
7: 3,918,066 (GRCm39) |
L26H |
probably benign |
Het |
| Mc4r |
A |
T |
18: 66,992,918 (GRCm39) |
V65E |
probably damaging |
Het |
| Mgam |
G |
A |
6: 40,646,797 (GRCm39) |
G708R |
probably damaging |
Het |
| Mllt6 |
A |
G |
11: 97,563,395 (GRCm39) |
D326G |
probably benign |
Het |
| Myo7a |
A |
T |
7: 97,722,331 (GRCm39) |
V1198D |
probably damaging |
Het |
| Nampt |
T |
C |
12: 32,883,037 (GRCm39) |
V74A |
probably damaging |
Het |
| Nlrp4b |
G |
C |
7: 10,449,266 (GRCm39) |
V123L |
probably benign |
Het |
| Ntpcr |
T |
A |
8: 126,472,141 (GRCm39) |
L150Q |
probably damaging |
Het |
| Obscn |
C |
T |
11: 58,997,163 (GRCm39) |
E1513K |
probably damaging |
Het |
| Ola1 |
T |
C |
2: 72,987,099 (GRCm39) |
K178E |
possibly damaging |
Het |
| Opalin |
T |
C |
19: 41,056,070 (GRCm39) |
|
probably null |
Het |
| Or10g6 |
A |
G |
9: 39,934,541 (GRCm39) |
N284S |
probably damaging |
Het |
| Or13a20 |
A |
T |
7: 140,232,419 (GRCm39) |
I176F |
probably damaging |
Het |
| Or2ad1 |
C |
T |
13: 21,326,934 (GRCm39) |
V98I |
probably benign |
Het |
| Or2w2 |
C |
T |
13: 21,757,711 (GRCm39) |
G305D |
probably damaging |
Het |
| Or3a10 |
A |
T |
11: 73,935,786 (GRCm39) |
F105I |
probably damaging |
Het |
| Or51ah3 |
C |
T |
7: 103,209,773 (GRCm39) |
P30S |
probably benign |
Het |
| Or52ae9 |
T |
C |
7: 103,390,028 (GRCm39) |
M140V |
probably benign |
Het |
| Or52e15 |
A |
T |
7: 104,645,315 (GRCm39) |
F265L |
possibly damaging |
Het |
| Or5p62 |
A |
G |
7: 107,771,090 (GRCm39) |
V287A |
probably benign |
Het |
| Or7a35 |
T |
C |
10: 78,853,159 (GRCm39) |
M1T |
probably null |
Het |
| P2ry12 |
A |
G |
3: 59,125,199 (GRCm39) |
F159L |
probably benign |
Het |
| Paqr7 |
T |
C |
4: 134,234,592 (GRCm39) |
|
probably null |
Het |
| Parp1 |
T |
C |
1: 180,415,578 (GRCm39) |
S466P |
probably benign |
Het |
| Parp4 |
T |
A |
14: 56,864,838 (GRCm39) |
|
probably null |
Het |
| Pcdh1 |
T |
C |
18: 38,322,977 (GRCm39) |
D952G |
probably damaging |
Het |
| Pde6c |
T |
C |
19: 38,140,146 (GRCm39) |
S336P |
possibly damaging |
Het |
| Pgk2 |
T |
C |
17: 40,519,398 (GRCm39) |
D10G |
probably benign |
Het |
| Phf20l1 |
A |
G |
15: 66,504,674 (GRCm39) |
T771A |
probably damaging |
Het |
| Pkdrej |
A |
G |
15: 85,705,372 (GRCm39) |
V188A |
possibly damaging |
Het |
| Plekhm1 |
A |
G |
11: 103,285,682 (GRCm39) |
L251P |
probably damaging |
Het |
| Prex2 |
A |
T |
1: 11,270,179 (GRCm39) |
N1288I |
probably benign |
Het |
| Sarnp |
T |
C |
10: 128,669,191 (GRCm39) |
L16P |
probably damaging |
Het |
| Scgb3a2 |
T |
C |
18: 43,900,033 (GRCm39) |
|
probably benign |
Het |
| Scn11a |
A |
T |
9: 119,584,148 (GRCm39) |
I1489N |
probably damaging |
Het |
| Scn3a |
A |
T |
2: 65,302,729 (GRCm39) |
L1239Q |
probably damaging |
Het |
| Shisa9 |
T |
C |
16: 12,085,521 (GRCm39) |
S377P |
probably benign |
Het |
| Slc22a30 |
T |
A |
19: 8,313,136 (GRCm39) |
T550S |
probably damaging |
Het |
| Slc25a11 |
T |
C |
11: 70,535,651 (GRCm39) |
T296A |
probably benign |
Het |
| Slc35f1 |
T |
A |
10: 52,938,532 (GRCm39) |
|
probably null |
Het |
| Slc6a13 |
A |
G |
6: 121,311,811 (GRCm39) |
E396G |
probably damaging |
Het |
| Spata31d1c |
T |
C |
13: 65,183,985 (GRCm39) |
I509T |
probably benign |
Het |
| Srsf9 |
C |
A |
5: 115,465,481 (GRCm39) |
Y9* |
probably null |
Het |
| Tasor2 |
T |
C |
13: 3,634,759 (GRCm39) |
T683A |
possibly damaging |
Het |
| Tbx20 |
T |
C |
9: 24,636,795 (GRCm39) |
I431V |
probably benign |
Het |
| Tespa1 |
G |
A |
10: 130,184,119 (GRCm39) |
G67S |
probably benign |
Het |
| Trhde |
A |
T |
10: 114,424,405 (GRCm39) |
V460E |
possibly damaging |
Het |
| Trip12 |
A |
T |
1: 84,708,342 (GRCm39) |
F1739I |
probably benign |
Het |
| Ugcg |
C |
T |
4: 59,207,798 (GRCm39) |
P46S |
probably benign |
Het |
| Umodl1 |
G |
A |
17: 31,187,524 (GRCm39) |
R196H |
probably damaging |
Het |
| Vezf1 |
G |
T |
11: 87,972,447 (GRCm39) |
M269I |
probably benign |
Het |
| Vmn1r35 |
A |
T |
6: 66,656,550 (GRCm39) |
M40K |
probably benign |
Het |
| Vmn1r9 |
G |
T |
6: 57,048,300 (GRCm39) |
C125F |
probably benign |
Het |
| Vmn2r12 |
C |
A |
5: 109,239,594 (GRCm39) |
G323V |
probably benign |
Het |
| Vmn2r79 |
A |
T |
7: 86,651,555 (GRCm39) |
H318L |
probably benign |
Het |
| Zfhx3 |
T |
A |
8: 109,520,167 (GRCm39) |
S430T |
probably benign |
Het |
|
| Other mutations in Disp2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00790:Disp2
|
APN |
2 |
118,616,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00970:Disp2
|
APN |
2 |
118,622,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01790:Disp2
|
APN |
2 |
118,621,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01809:Disp2
|
APN |
2 |
118,617,745 (GRCm39) |
splice site |
probably benign |
|
|
IGL02069:Disp2
|
APN |
2 |
118,621,161 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL02140:Disp2
|
APN |
2 |
118,621,350 (GRCm39) |
missense |
probably benign |
|
|
IGL02143:Disp2
|
APN |
2 |
118,620,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02155:Disp2
|
APN |
2 |
118,622,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02884:Disp2
|
APN |
2 |
118,618,032 (GRCm39) |
splice site |
probably benign |
|
|
IGL03113:Disp2
|
APN |
2 |
118,621,259 (GRCm39) |
splice site |
probably null |
|
|
IGL03194:Disp2
|
APN |
2 |
118,618,110 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4453001:Disp2
|
UTSW |
2 |
118,618,125 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0109:Disp2
|
UTSW |
2 |
118,622,297 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0126:Disp2
|
UTSW |
2 |
118,620,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0603:Disp2
|
UTSW |
2 |
118,622,487 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0610:Disp2
|
UTSW |
2 |
118,622,717 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0639:Disp2
|
UTSW |
2 |
118,621,325 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R0673:Disp2
|
UTSW |
2 |
118,621,325 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R0755:Disp2
|
UTSW |
2 |
118,620,243 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0781:Disp2
|
UTSW |
2 |
118,620,920 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1110:Disp2
|
UTSW |
2 |
118,620,920 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1148:Disp2
|
UTSW |
2 |
118,636,899 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1148:Disp2
|
UTSW |
2 |
118,636,899 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1243:Disp2
|
UTSW |
2 |
118,622,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1587:Disp2
|
UTSW |
2 |
118,622,064 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1739:Disp2
|
UTSW |
2 |
118,622,031 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1771:Disp2
|
UTSW |
2 |
118,621,778 (GRCm39) |
nonsense |
probably null |
|
|
R1918:Disp2
|
UTSW |
2 |
118,622,408 (GRCm39) |
missense |
probably benign |
|
|
R1956:Disp2
|
UTSW |
2 |
118,622,704 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2167:Disp2
|
UTSW |
2 |
118,622,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2206:Disp2
|
UTSW |
2 |
118,622,725 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4031:Disp2
|
UTSW |
2 |
118,622,361 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4617:Disp2
|
UTSW |
2 |
118,620,643 (GRCm39) |
missense |
probably benign |
|
|
R4656:Disp2
|
UTSW |
2 |
118,621,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4684:Disp2
|
UTSW |
2 |
118,623,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4696:Disp2
|
UTSW |
2 |
118,622,165 (GRCm39) |
nonsense |
probably null |
|
|
R4697:Disp2
|
UTSW |
2 |
118,622,165 (GRCm39) |
nonsense |
probably null |
|
|
R4738:Disp2
|
UTSW |
2 |
118,620,807 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4834:Disp2
|
UTSW |
2 |
118,622,985 (GRCm39) |
missense |
probably benign |
0.09 |
|
R4914:Disp2
|
UTSW |
2 |
118,620,935 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4915:Disp2
|
UTSW |
2 |
118,620,935 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4918:Disp2
|
UTSW |
2 |
118,620,935 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5045:Disp2
|
UTSW |
2 |
118,622,543 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5208:Disp2
|
UTSW |
2 |
118,622,286 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5303:Disp2
|
UTSW |
2 |
118,641,329 (GRCm39) |
unclassified |
probably benign |
|
|
R5350:Disp2
|
UTSW |
2 |
118,618,056 (GRCm39) |
missense |
probably benign |
0.23 |
|
R5355:Disp2
|
UTSW |
2 |
118,617,392 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6011:Disp2
|
UTSW |
2 |
118,621,301 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R6031:Disp2
|
UTSW |
2 |
118,620,275 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6031:Disp2
|
UTSW |
2 |
118,620,275 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6139:Disp2
|
UTSW |
2 |
118,621,143 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6169:Disp2
|
UTSW |
2 |
118,622,031 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6187:Disp2
|
UTSW |
2 |
118,622,624 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6209:Disp2
|
UTSW |
2 |
118,617,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6250:Disp2
|
UTSW |
2 |
118,621,247 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6392:Disp2
|
UTSW |
2 |
118,621,230 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7138:Disp2
|
UTSW |
2 |
118,617,361 (GRCm39) |
missense |
probably benign |
|
|
R7156:Disp2
|
UTSW |
2 |
118,622,292 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7230:Disp2
|
UTSW |
2 |
118,622,286 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7400:Disp2
|
UTSW |
2 |
118,622,367 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7460:Disp2
|
UTSW |
2 |
118,620,261 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7505:Disp2
|
UTSW |
2 |
118,621,569 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7542:Disp2
|
UTSW |
2 |
118,621,599 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7728:Disp2
|
UTSW |
2 |
118,621,961 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7757:Disp2
|
UTSW |
2 |
118,621,391 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7798:Disp2
|
UTSW |
2 |
118,622,360 (GRCm39) |
missense |
probably benign |
|
|
R7945:Disp2
|
UTSW |
2 |
118,623,270 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8013:Disp2
|
UTSW |
2 |
118,620,163 (GRCm39) |
nonsense |
probably null |
|
|
R8085:Disp2
|
UTSW |
2 |
118,617,452 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8179:Disp2
|
UTSW |
2 |
118,623,030 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8288:Disp2
|
UTSW |
2 |
118,620,762 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8345:Disp2
|
UTSW |
2 |
118,641,284 (GRCm39) |
missense |
unknown |
|
|
R8385:Disp2
|
UTSW |
2 |
118,620,891 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8700:Disp2
|
UTSW |
2 |
118,620,340 (GRCm39) |
nonsense |
probably null |
|
|
R8808:Disp2
|
UTSW |
2 |
118,620,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8880:Disp2
|
UTSW |
2 |
118,621,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8997:Disp2
|
UTSW |
2 |
118,617,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9022:Disp2
|
UTSW |
2 |
118,621,179 (GRCm39) |
missense |
probably benign |
0.22 |
|
R9181:Disp2
|
UTSW |
2 |
118,617,393 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9660:Disp2
|
UTSW |
2 |
118,620,627 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Disp2
|
UTSW |
2 |
118,621,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Disp2
|
UTSW |
2 |
118,620,183 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGACCTCCTCTCCATATAAGCAGGC -3'
(R):5'- TGGCTGACTGTTGGGAAGCATC -3'
Sequencing Primer
(F):5'- CTGGATCAGGCAAGATTCCC -3'
(R):5'- CTGTTGGGAAGCATCACAGG -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation