Incidental Mutation 'R1781:Parp4'
| ID |
195324 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Parp4
|
| Ensembl Gene |
ENSMUSG00000054509 |
| Gene Name |
poly (ADP-ribose) polymerase family, member 4 |
| Synonyms |
VPARP, Adprtl1, C030027K23Rik, VAULT3, p193, PH5P, E230037B21Rik |
| MMRRC Submission |
039812-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.146)
|
| Stock # |
R1781 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
14 |
| Chromosomal Location |
56813076-56897251 bp(+) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
T to A
at 56864838 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000124258
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000161553]
|
| AlphaFold |
E9PYK3 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000161553
|
| SMART Domains |
Protein: ENSMUSP00000124258
Gene: ENSMUSG00000054509
| Domain | Start | End | E-Value | Type |
|---|
|
BRCT
|
3 |
84 |
4.32e-9 |
SMART |
|
low complexity region
|
97 |
104 |
N/A |
INTRINSIC |
|
SCOP:d1a26_1
|
252 |
352 |
2e-19 |
SMART |
|
Pfam:PARP
|
371 |
559 |
1.8e-50 |
PFAM |
|
VIT
|
600 |
728 |
1.5e-57 |
SMART |
|
VWA
|
867 |
1030 |
6.08e-13 |
SMART |
|
Blast:14_3_3
|
1149 |
1205 |
5e-10 |
BLAST |
|
low complexity region
|
1255 |
1264 |
N/A |
INTRINSIC |
|
low complexity region
|
1348 |
1362 |
N/A |
INTRINSIC |
|
low complexity region
|
1371 |
1394 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1395 |
1416 |
4.48e-6 |
PROSPERO |
|
Pfam:Drf_FH1
|
1443 |
1542 |
3.3e-15 |
PFAM |
|
low complexity region
|
1553 |
1587 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
1588 |
1608 |
2.45e-5 |
PROSPERO |
|
low complexity region
|
1695 |
1708 |
N/A |
INTRINSIC |
|
low complexity region
|
1739 |
1750 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 97.3%
- 3x: 96.7%
- 10x: 94.6%
- 20x: 90.1%
|
| Validation Efficiency |
97% (88/91) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygous null mutants are helathy and fertile. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 90 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadacl2 |
A |
G |
3: 59,932,117 (GRCm39) |
K211E |
probably damaging |
Het |
| Abca13 |
T |
A |
11: 9,219,194 (GRCm39) |
L376Q |
probably damaging |
Het |
| Abca17 |
T |
C |
17: 24,486,531 (GRCm39) |
T1499A |
possibly damaging |
Het |
| Anks6 |
A |
C |
4: 47,043,639 (GRCm39) |
N363K |
possibly damaging |
Het |
| Apob |
T |
A |
12: 8,059,603 (GRCm39) |
I2695N |
possibly damaging |
Het |
| Arhgef18 |
C |
T |
8: 3,430,495 (GRCm39) |
R123W |
probably damaging |
Het |
| Atg14 |
T |
A |
14: 47,786,607 (GRCm39) |
|
probably null |
Het |
| Atg2a |
A |
T |
19: 6,306,243 (GRCm39) |
I1368F |
probably damaging |
Het |
| Btbd9 |
A |
G |
17: 30,732,567 (GRCm39) |
S373P |
probably damaging |
Het |
| Ccdc83 |
T |
C |
7: 89,899,749 (GRCm39) |
E41G |
probably damaging |
Het |
| Ccnh |
T |
C |
13: 85,354,254 (GRCm39) |
S233P |
possibly damaging |
Het |
| Cdh8 |
T |
C |
8: 99,917,094 (GRCm39) |
|
probably null |
Het |
| Cdh8 |
A |
T |
8: 100,006,290 (GRCm39) |
I99N |
probably damaging |
Het |
| Cdr2 |
G |
A |
7: 120,557,268 (GRCm39) |
P419L |
probably benign |
Het |
| Cds1 |
T |
A |
5: 101,960,416 (GRCm39) |
I289K |
possibly damaging |
Het |
| Cherp |
G |
A |
8: 73,221,615 (GRCm39) |
T394I |
probably damaging |
Het |
| Cyp4f17 |
T |
G |
17: 32,742,993 (GRCm39) |
I222S |
possibly damaging |
Het |
| Dcc |
A |
G |
18: 71,511,788 (GRCm39) |
S856P |
probably benign |
Het |
| Dcp1a |
C |
T |
14: 30,235,032 (GRCm39) |
T221I |
probably benign |
Het |
| Ddx10 |
A |
G |
9: 53,118,845 (GRCm39) |
S475P |
probably damaging |
Het |
| Dennd5b |
G |
T |
6: 148,928,896 (GRCm39) |
A759E |
probably damaging |
Het |
| Disp2 |
G |
A |
2: 118,623,042 (GRCm39) |
G1258D |
probably damaging |
Het |
| Fhdc1 |
A |
T |
3: 84,356,111 (GRCm39) |
D444E |
probably damaging |
Het |
| Fhod1 |
T |
C |
8: 106,074,421 (GRCm39) |
|
probably benign |
Het |
| Gcnt7 |
T |
C |
2: 172,296,800 (GRCm39) |
K8R |
probably benign |
Het |
| Gk5 |
C |
T |
9: 96,015,508 (GRCm39) |
T108I |
possibly damaging |
Het |
| Gm8214 |
C |
A |
1: 183,414,129 (GRCm39) |
|
noncoding transcript |
Het |
| Gnl1 |
A |
T |
17: 36,298,638 (GRCm39) |
I434F |
probably damaging |
Het |
| Golga2 |
T |
C |
2: 32,196,588 (GRCm39) |
Y986H |
probably damaging |
Het |
| Gpr21 |
T |
C |
2: 37,407,550 (GRCm39) |
V32A |
probably benign |
Het |
| Grb14 |
A |
T |
2: 64,805,899 (GRCm39) |
|
probably null |
Het |
| H6pd |
A |
T |
4: 150,080,388 (GRCm39) |
F144L |
probably damaging |
Het |
| Hunk |
A |
G |
16: 90,229,448 (GRCm39) |
Y27C |
probably damaging |
Het |
| Ints7 |
C |
T |
1: 191,328,396 (GRCm39) |
T223M |
possibly damaging |
Het |
| Kcnmb2 |
T |
C |
3: 32,233,152 (GRCm39) |
|
probably null |
Het |
| Lilra6 |
A |
T |
7: 3,918,066 (GRCm39) |
L26H |
probably benign |
Het |
| Mc4r |
A |
T |
18: 66,992,918 (GRCm39) |
V65E |
probably damaging |
Het |
| Mgam |
G |
A |
6: 40,646,797 (GRCm39) |
G708R |
probably damaging |
Het |
| Mllt6 |
A |
G |
11: 97,563,395 (GRCm39) |
D326G |
probably benign |
Het |
| Myo7a |
A |
T |
7: 97,722,331 (GRCm39) |
V1198D |
probably damaging |
Het |
| Nampt |
T |
C |
12: 32,883,037 (GRCm39) |
V74A |
probably damaging |
Het |
| Nlrp4b |
G |
C |
7: 10,449,266 (GRCm39) |
V123L |
probably benign |
Het |
| Ntpcr |
T |
A |
8: 126,472,141 (GRCm39) |
L150Q |
probably damaging |
Het |
| Obscn |
C |
T |
11: 58,997,163 (GRCm39) |
E1513K |
probably damaging |
Het |
| Ola1 |
T |
C |
2: 72,987,099 (GRCm39) |
K178E |
possibly damaging |
Het |
| Opalin |
T |
C |
19: 41,056,070 (GRCm39) |
|
probably null |
Het |
| Or10g6 |
A |
G |
9: 39,934,541 (GRCm39) |
N284S |
probably damaging |
Het |
| Or13a20 |
A |
T |
7: 140,232,419 (GRCm39) |
I176F |
probably damaging |
Het |
| Or2ad1 |
C |
T |
13: 21,326,934 (GRCm39) |
V98I |
probably benign |
Het |
| Or2w2 |
C |
T |
13: 21,757,711 (GRCm39) |
G305D |
probably damaging |
Het |
| Or3a10 |
A |
T |
11: 73,935,786 (GRCm39) |
F105I |
probably damaging |
Het |
| Or51ah3 |
C |
T |
7: 103,209,773 (GRCm39) |
P30S |
probably benign |
Het |
| Or52ae9 |
T |
C |
7: 103,390,028 (GRCm39) |
M140V |
probably benign |
Het |
| Or52e15 |
A |
T |
7: 104,645,315 (GRCm39) |
F265L |
possibly damaging |
Het |
| Or5p62 |
A |
G |
7: 107,771,090 (GRCm39) |
V287A |
probably benign |
Het |
| Or7a35 |
T |
C |
10: 78,853,159 (GRCm39) |
M1T |
probably null |
Het |
| P2ry12 |
A |
G |
3: 59,125,199 (GRCm39) |
F159L |
probably benign |
Het |
| Paqr7 |
T |
C |
4: 134,234,592 (GRCm39) |
|
probably null |
Het |
| Parp1 |
T |
C |
1: 180,415,578 (GRCm39) |
S466P |
probably benign |
Het |
| Pcdh1 |
T |
C |
18: 38,322,977 (GRCm39) |
D952G |
probably damaging |
Het |
| Pde6c |
T |
C |
19: 38,140,146 (GRCm39) |
S336P |
possibly damaging |
Het |
| Pgk2 |
T |
C |
17: 40,519,398 (GRCm39) |
D10G |
probably benign |
Het |
| Phf20l1 |
A |
G |
15: 66,504,674 (GRCm39) |
T771A |
probably damaging |
Het |
| Pkdrej |
A |
G |
15: 85,705,372 (GRCm39) |
V188A |
possibly damaging |
Het |
| Plekhm1 |
A |
G |
11: 103,285,682 (GRCm39) |
L251P |
probably damaging |
Het |
| Prex2 |
A |
T |
1: 11,270,179 (GRCm39) |
N1288I |
probably benign |
Het |
| Sarnp |
T |
C |
10: 128,669,191 (GRCm39) |
L16P |
probably damaging |
Het |
| Scgb3a2 |
T |
C |
18: 43,900,033 (GRCm39) |
|
probably benign |
Het |
| Scn11a |
A |
T |
9: 119,584,148 (GRCm39) |
I1489N |
probably damaging |
Het |
| Scn3a |
A |
T |
2: 65,302,729 (GRCm39) |
L1239Q |
probably damaging |
Het |
| Shisa9 |
T |
C |
16: 12,085,521 (GRCm39) |
S377P |
probably benign |
Het |
| Slc22a30 |
T |
A |
19: 8,313,136 (GRCm39) |
T550S |
probably damaging |
Het |
| Slc25a11 |
T |
C |
11: 70,535,651 (GRCm39) |
T296A |
probably benign |
Het |
| Slc35f1 |
T |
A |
10: 52,938,532 (GRCm39) |
|
probably null |
Het |
| Slc6a13 |
A |
G |
6: 121,311,811 (GRCm39) |
E396G |
probably damaging |
Het |
| Spata31d1c |
T |
C |
13: 65,183,985 (GRCm39) |
I509T |
probably benign |
Het |
| Srsf9 |
C |
A |
5: 115,465,481 (GRCm39) |
Y9* |
probably null |
Het |
| Tasor2 |
T |
C |
13: 3,634,759 (GRCm39) |
T683A |
possibly damaging |
Het |
| Tbx20 |
T |
C |
9: 24,636,795 (GRCm39) |
I431V |
probably benign |
Het |
| Tespa1 |
G |
A |
10: 130,184,119 (GRCm39) |
G67S |
probably benign |
Het |
| Trhde |
A |
T |
10: 114,424,405 (GRCm39) |
V460E |
possibly damaging |
Het |
| Trip12 |
A |
T |
1: 84,708,342 (GRCm39) |
F1739I |
probably benign |
Het |
| Ugcg |
C |
T |
4: 59,207,798 (GRCm39) |
P46S |
probably benign |
Het |
| Umodl1 |
G |
A |
17: 31,187,524 (GRCm39) |
R196H |
probably damaging |
Het |
| Vezf1 |
G |
T |
11: 87,972,447 (GRCm39) |
M269I |
probably benign |
Het |
| Vmn1r35 |
A |
T |
6: 66,656,550 (GRCm39) |
M40K |
probably benign |
Het |
| Vmn1r9 |
G |
T |
6: 57,048,300 (GRCm39) |
C125F |
probably benign |
Het |
| Vmn2r12 |
C |
A |
5: 109,239,594 (GRCm39) |
G323V |
probably benign |
Het |
| Vmn2r79 |
A |
T |
7: 86,651,555 (GRCm39) |
H318L |
probably benign |
Het |
| Zfhx3 |
T |
A |
8: 109,520,167 (GRCm39) |
S430T |
probably benign |
Het |
|
| Other mutations in Parp4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00479:Parp4
|
APN |
14 |
56,853,917 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL00571:Parp4
|
APN |
14 |
56,884,810 (GRCm39) |
missense |
unknown |
|
|
IGL00737:Parp4
|
APN |
14 |
56,821,620 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00793:Parp4
|
APN |
14 |
56,840,334 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL01108:Parp4
|
APN |
14 |
56,844,897 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01131:Parp4
|
APN |
14 |
56,823,217 (GRCm39) |
splice site |
probably benign |
|
|
IGL01485:Parp4
|
APN |
14 |
56,859,661 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
IGL01704:Parp4
|
APN |
14 |
56,839,783 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01993:Parp4
|
APN |
14 |
56,848,245 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL02125:Parp4
|
APN |
14 |
56,827,959 (GRCm39) |
missense |
probably benign |
0.33 |
|
IGL02851:Parp4
|
APN |
14 |
56,886,326 (GRCm39) |
missense |
unknown |
|
|
IGL02863:Parp4
|
APN |
14 |
56,886,243 (GRCm39) |
missense |
unknown |
|
|
IGL03065:Parp4
|
APN |
14 |
56,875,326 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL03117:Parp4
|
APN |
14 |
56,840,313 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL03271:Parp4
|
APN |
14 |
56,823,082 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL03309:Parp4
|
APN |
14 |
56,825,265 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL03408:Parp4
|
APN |
14 |
56,839,865 (GRCm39) |
missense |
probably damaging |
0.99 |
|
poisonous
|
UTSW |
14 |
56,873,205 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R0515_Parp4_195
|
UTSW |
14 |
56,851,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
toxic
|
UTSW |
14 |
56,866,615 (GRCm39) |
missense |
probably benign |
0.28 |
|
venomous
|
UTSW |
14 |
56,827,355 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
virulent
|
UTSW |
14 |
56,825,235 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0278:Parp4
|
UTSW |
14 |
56,844,980 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0320:Parp4
|
UTSW |
14 |
56,825,953 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0445:Parp4
|
UTSW |
14 |
56,840,205 (GRCm39) |
splice site |
probably null |
|
|
R0452:Parp4
|
UTSW |
14 |
56,886,300 (GRCm39) |
missense |
unknown |
|
|
R0511:Parp4
|
UTSW |
14 |
56,873,172 (GRCm39) |
splice site |
probably benign |
|
|
R0515:Parp4
|
UTSW |
14 |
56,851,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0608:Parp4
|
UTSW |
14 |
56,839,861 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0800:Parp4
|
UTSW |
14 |
56,827,408 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0959:Parp4
|
UTSW |
14 |
56,885,576 (GRCm39) |
missense |
unknown |
|
|
R1207:Parp4
|
UTSW |
14 |
56,885,339 (GRCm39) |
missense |
unknown |
|
|
R1207:Parp4
|
UTSW |
14 |
56,885,339 (GRCm39) |
missense |
unknown |
|
|
R1342:Parp4
|
UTSW |
14 |
56,827,854 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1520:Parp4
|
UTSW |
14 |
56,835,863 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1565:Parp4
|
UTSW |
14 |
56,827,329 (GRCm39) |
splice site |
probably benign |
|
|
R1574:Parp4
|
UTSW |
14 |
56,839,752 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1574:Parp4
|
UTSW |
14 |
56,839,752 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1649:Parp4
|
UTSW |
14 |
56,827,885 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1666:Parp4
|
UTSW |
14 |
56,861,620 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1799:Parp4
|
UTSW |
14 |
56,885,589 (GRCm39) |
missense |
unknown |
|
|
R1823:Parp4
|
UTSW |
14 |
56,827,329 (GRCm39) |
splice site |
probably benign |
|
|
R1859:Parp4
|
UTSW |
14 |
56,886,372 (GRCm39) |
missense |
unknown |
|
|
R1919:Parp4
|
UTSW |
14 |
56,861,474 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2000:Parp4
|
UTSW |
14 |
56,851,181 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2032:Parp4
|
UTSW |
14 |
56,866,553 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R2034:Parp4
|
UTSW |
14 |
56,871,720 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2177:Parp4
|
UTSW |
14 |
56,896,746 (GRCm39) |
missense |
unknown |
|
|
R2291:Parp4
|
UTSW |
14 |
56,851,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2865:Parp4
|
UTSW |
14 |
56,851,181 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3012:Parp4
|
UTSW |
14 |
56,832,873 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3841:Parp4
|
UTSW |
14 |
56,825,235 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3913:Parp4
|
UTSW |
14 |
56,857,975 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4064:Parp4
|
UTSW |
14 |
56,861,597 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4201:Parp4
|
UTSW |
14 |
56,829,848 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4288:Parp4
|
UTSW |
14 |
56,844,951 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4360:Parp4
|
UTSW |
14 |
56,866,661 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4506:Parp4
|
UTSW |
14 |
56,889,761 (GRCm39) |
missense |
unknown |
|
|
R4577:Parp4
|
UTSW |
14 |
56,827,867 (GRCm39) |
missense |
probably benign |
0.33 |
|
R4633:Parp4
|
UTSW |
14 |
56,885,048 (GRCm39) |
missense |
unknown |
|
|
R4762:Parp4
|
UTSW |
14 |
56,848,267 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4836:Parp4
|
UTSW |
14 |
56,823,195 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4974:Parp4
|
UTSW |
14 |
56,827,355 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5049:Parp4
|
UTSW |
14 |
56,873,188 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5479:Parp4
|
UTSW |
14 |
56,861,552 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5683:Parp4
|
UTSW |
14 |
56,884,886 (GRCm39) |
nonsense |
probably null |
|
|
R5884:Parp4
|
UTSW |
14 |
56,852,207 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5965:Parp4
|
UTSW |
14 |
56,861,489 (GRCm39) |
missense |
probably benign |
0.11 |
|
R6001:Parp4
|
UTSW |
14 |
56,878,740 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6027:Parp4
|
UTSW |
14 |
56,866,615 (GRCm39) |
missense |
probably benign |
0.28 |
|
R6230:Parp4
|
UTSW |
14 |
56,844,990 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6242:Parp4
|
UTSW |
14 |
56,832,856 (GRCm39) |
nonsense |
probably null |
|
|
R6355:Parp4
|
UTSW |
14 |
56,839,757 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R6414:Parp4
|
UTSW |
14 |
56,864,838 (GRCm39) |
splice site |
probably null |
|
|
R6418:Parp4
|
UTSW |
14 |
56,858,108 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6477:Parp4
|
UTSW |
14 |
56,884,694 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6542:Parp4
|
UTSW |
14 |
56,885,339 (GRCm39) |
missense |
unknown |
|
|
R6759:Parp4
|
UTSW |
14 |
56,857,947 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6995:Parp4
|
UTSW |
14 |
56,851,196 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7002:Parp4
|
UTSW |
14 |
56,839,861 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7026:Parp4
|
UTSW |
14 |
56,858,049 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7062:Parp4
|
UTSW |
14 |
56,852,216 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R7101:Parp4
|
UTSW |
14 |
56,827,430 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7124:Parp4
|
UTSW |
14 |
56,840,256 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7162:Parp4
|
UTSW |
14 |
56,886,333 (GRCm39) |
missense |
unknown |
|
|
R7293:Parp4
|
UTSW |
14 |
56,885,303 (GRCm39) |
small deletion |
probably benign |
|
|
R7297:Parp4
|
UTSW |
14 |
56,885,138 (GRCm39) |
missense |
not run |
|
|
R7337:Parp4
|
UTSW |
14 |
56,839,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7539:Parp4
|
UTSW |
14 |
56,873,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7575:Parp4
|
UTSW |
14 |
56,875,375 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7808:Parp4
|
UTSW |
14 |
56,873,205 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R7854:Parp4
|
UTSW |
14 |
56,896,805 (GRCm39) |
missense |
unknown |
|
|
R7960:Parp4
|
UTSW |
14 |
56,832,708 (GRCm39) |
splice site |
probably null |
|
|
R8152:Parp4
|
UTSW |
14 |
56,884,703 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8344:Parp4
|
UTSW |
14 |
56,886,186 (GRCm39) |
missense |
unknown |
|
|
R8416:Parp4
|
UTSW |
14 |
56,825,271 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8726:Parp4
|
UTSW |
14 |
56,866,556 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8752:Parp4
|
UTSW |
14 |
56,886,073 (GRCm39) |
missense |
unknown |
|
|
R8804:Parp4
|
UTSW |
14 |
56,853,900 (GRCm39) |
nonsense |
probably null |
|
|
R9046:Parp4
|
UTSW |
14 |
56,864,927 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9176:Parp4
|
UTSW |
14 |
56,873,274 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R9303:Parp4
|
UTSW |
14 |
56,852,224 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9303:Parp4
|
UTSW |
14 |
56,832,790 (GRCm39) |
frame shift |
probably null |
|
|
R9305:Parp4
|
UTSW |
14 |
56,852,224 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9305:Parp4
|
UTSW |
14 |
56,832,790 (GRCm39) |
frame shift |
probably null |
|
|
R9360:Parp4
|
UTSW |
14 |
56,878,775 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9430:Parp4
|
UTSW |
14 |
56,866,673 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9491:Parp4
|
UTSW |
14 |
56,832,828 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9729:Parp4
|
UTSW |
14 |
56,885,888 (GRCm39) |
missense |
unknown |
|
|
RF020:Parp4
|
UTSW |
14 |
56,884,806 (GRCm39) |
missense |
unknown |
|
|
Z1177:Parp4
|
UTSW |
14 |
56,829,824 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
|
| Posted On |
2014-05-23 |
Incidental Mutation