Incidental Mutation 'R1771:Clca3a2'
| ID |
196555 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Clca3a2
|
| Ensembl Gene |
ENSMUSG00000028262 |
| Gene Name |
chloride channel accessory 3A2 |
| Synonyms |
Clca2 |
| MMRRC Submission |
039802-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.089)
|
| Stock # |
R1771 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
144502320-144525255 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 144787171 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Glutamic Acid
at position 500
(V500E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000143161
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000040465]
[ENSMUST00000198993]
|
| AlphaFold |
Q9EQR4 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000040465
AA Change: V500E
PolyPhen 2
Score 0.121 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000036029
Gene: ENSMUSG00000036960
AA Change: V500E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
29 |
N/A |
INTRINSIC |
|
VWA
|
309 |
485 |
3.55e-5 |
SMART |
|
low complexity region
|
739 |
754 |
N/A |
INTRINSIC |
|
Blast:FN3
|
765 |
875 |
5e-21 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000198993
AA Change: V500E
PolyPhen 2
Score 0.121 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000143161
Gene: ENSMUSG00000036960
AA Change: V500E
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:CLCA_N
|
7 |
265 |
1.7e-121 |
PFAM |
|
VWA
|
309 |
485 |
2.2e-7 |
SMART |
|
Pfam:DUF1973
|
494 |
674 |
7.8e-75 |
PFAM |
|
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.9%
- 10x: 95.2%
- 20x: 92.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 102 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acss3 |
A |
G |
10: 106,773,061 (GRCm39) |
S642P |
probably damaging |
Het |
| Adam30 |
T |
C |
3: 98,068,835 (GRCm39) |
S95P |
possibly damaging |
Het |
| Ahnak |
G |
A |
19: 8,991,117 (GRCm39) |
V4134I |
probably benign |
Het |
| Ankrd13a |
T |
C |
5: 114,941,649 (GRCm39) |
V512A |
probably benign |
Het |
| Asph |
A |
T |
4: 9,598,773 (GRCm39) |
S149R |
probably damaging |
Het |
| Atp2b4 |
C |
A |
1: 133,660,131 (GRCm39) |
V384L |
probably damaging |
Het |
| Atp8a1 |
A |
G |
5: 67,805,074 (GRCm39) |
W1014R |
probably damaging |
Het |
| Cand1 |
A |
C |
10: 119,044,211 (GRCm39) |
N1054K |
probably benign |
Het |
| Car15 |
A |
T |
16: 17,654,730 (GRCm39) |
V96E |
probably damaging |
Het |
| Cd1d1 |
T |
C |
3: 86,905,972 (GRCm39) |
E101G |
possibly damaging |
Het |
| Cd84 |
A |
G |
1: 171,700,317 (GRCm39) |
T145A |
possibly damaging |
Het |
| Ceacam1 |
T |
A |
7: 25,171,469 (GRCm39) |
T332S |
probably benign |
Het |
| Cul9 |
A |
T |
17: 46,848,738 (GRCm39) |
M666K |
probably benign |
Het |
| Dennd3 |
A |
G |
15: 73,426,950 (GRCm39) |
T776A |
possibly damaging |
Het |
| Dennd5a |
T |
C |
7: 109,517,893 (GRCm39) |
D581G |
probably damaging |
Het |
| Dgkh |
A |
G |
14: 78,846,967 (GRCm39) |
V371A |
probably damaging |
Het |
| Dhcr24 |
A |
G |
4: 106,435,450 (GRCm39) |
T314A |
probably benign |
Het |
| Diaph1 |
G |
T |
18: 38,024,071 (GRCm39) |
P589Q |
unknown |
Het |
| Disp2 |
C |
T |
2: 118,621,778 (GRCm39) |
Q837* |
probably null |
Het |
| Dusp3 |
A |
T |
11: 101,875,561 (GRCm39) |
M1K |
probably null |
Het |
| Ecpas |
A |
G |
4: 58,879,100 (GRCm39) |
I63T |
probably damaging |
Het |
| Eddm13 |
G |
T |
7: 6,280,541 (GRCm39) |
|
probably null |
Het |
| Erich3 |
A |
C |
3: 154,454,109 (GRCm39) |
D625A |
possibly damaging |
Het |
| Fat2 |
G |
A |
11: 55,201,691 (GRCm39) |
S461L |
probably benign |
Het |
| Fmn2 |
A |
G |
1: 174,436,342 (GRCm39) |
|
probably benign |
Het |
| Foxi1 |
A |
G |
11: 34,157,594 (GRCm39) |
Y144H |
probably damaging |
Het |
| Ftcd |
G |
A |
10: 76,423,202 (GRCm39) |
V458M |
probably damaging |
Het |
| Gm3604 |
C |
A |
13: 62,517,888 (GRCm39) |
G157* |
probably null |
Het |
| Gnpda1 |
C |
T |
18: 38,466,380 (GRCm39) |
R79Q |
probably benign |
Het |
| Gpr65 |
T |
A |
12: 98,242,259 (GRCm39) |
I304K |
probably damaging |
Het |
| Grem1 |
T |
C |
2: 113,580,021 (GRCm39) |
E160G |
probably benign |
Het |
| Gria2 |
T |
A |
3: 80,599,608 (GRCm39) |
K759* |
probably null |
Het |
| Gsg1l |
A |
G |
7: 125,557,745 (GRCm39) |
S128P |
probably damaging |
Het |
| Hdac1 |
A |
T |
4: 129,415,221 (GRCm39) |
I240N |
probably damaging |
Het |
| Hic2 |
C |
T |
16: 17,076,578 (GRCm39) |
T469M |
probably benign |
Het |
| Hoxc10 |
A |
C |
15: 102,875,522 (GRCm39) |
D77A |
probably damaging |
Het |
| Itprid1 |
T |
C |
6: 55,875,132 (GRCm39) |
S361P |
probably benign |
Het |
| Klhl14 |
T |
A |
18: 21,784,677 (GRCm39) |
H250L |
probably damaging |
Het |
| Klk1b24 |
A |
G |
7: 43,837,653 (GRCm39) |
|
probably null |
Het |
| Letm1 |
T |
A |
5: 33,926,811 (GRCm39) |
H162L |
probably damaging |
Het |
| Loxl3 |
A |
T |
6: 83,026,890 (GRCm39) |
Y573F |
probably damaging |
Het |
| Macf1 |
A |
T |
4: 123,405,901 (GRCm39) |
I330N |
probably damaging |
Het |
| Mchr1 |
T |
A |
15: 81,121,436 (GRCm39) |
I62N |
probably damaging |
Het |
| Mcm8 |
C |
T |
2: 132,685,476 (GRCm39) |
Q803* |
probably null |
Het |
| Msh3 |
T |
G |
13: 92,349,004 (GRCm39) |
D1075A |
probably benign |
Het |
| Msh6 |
T |
A |
17: 88,291,950 (GRCm39) |
V235D |
probably benign |
Het |
| Mthfd2l |
A |
T |
5: 91,122,254 (GRCm39) |
D253V |
probably damaging |
Het |
| Mtor |
T |
C |
4: 148,555,081 (GRCm39) |
V901A |
possibly damaging |
Het |
| Muc20 |
A |
T |
16: 32,614,222 (GRCm39) |
I385N |
probably damaging |
Het |
| Myo6 |
G |
T |
9: 80,193,082 (GRCm39) |
C829F |
probably damaging |
Het |
| Nbea |
T |
C |
3: 55,841,940 (GRCm39) |
I1914V |
probably benign |
Het |
| Ncor1 |
T |
C |
11: 62,217,938 (GRCm39) |
E1462G |
probably damaging |
Het |
| Necab1 |
A |
G |
4: 15,111,267 (GRCm39) |
Y54H |
probably damaging |
Het |
| Nlrp4b |
A |
G |
7: 10,452,520 (GRCm39) |
K15R |
probably damaging |
Het |
| Ntrk1 |
A |
G |
3: 87,696,937 (GRCm39) |
S139P |
probably benign |
Het |
| Oas1d |
T |
C |
5: 121,053,900 (GRCm39) |
F120S |
probably damaging |
Het |
| Ofd1 |
A |
G |
X: 165,189,002 (GRCm39) |
Y755H |
probably benign |
Het |
| Or10al2 |
A |
G |
17: 37,983,554 (GRCm39) |
I213M |
probably damaging |
Het |
| Or13a25 |
A |
G |
7: 140,248,048 (GRCm39) |
T276A |
probably benign |
Het |
| Or4f47 |
T |
G |
2: 111,973,065 (GRCm39) |
Y258* |
probably null |
Het |
| Or5c1 |
T |
A |
2: 37,222,430 (GRCm39) |
F224I |
probably benign |
Het |
| Or5p58 |
A |
C |
7: 107,694,816 (GRCm39) |
|
probably null |
Het |
| Or9s27 |
A |
G |
1: 92,516,837 (GRCm39) |
I262V |
probably benign |
Het |
| Plekha6 |
T |
C |
1: 133,201,651 (GRCm39) |
S355P |
probably benign |
Het |
| Prdm14 |
T |
C |
1: 13,189,082 (GRCm39) |
K421E |
probably damaging |
Het |
| Prss36 |
A |
G |
7: 127,532,625 (GRCm39) |
L731P |
probably damaging |
Het |
| Rad51d |
A |
G |
11: 82,774,764 (GRCm39) |
L97P |
probably damaging |
Het |
| Rbl1 |
C |
A |
2: 157,005,454 (GRCm39) |
|
probably null |
Het |
| Rnh1 |
G |
T |
7: 140,744,519 (GRCm39) |
A52D |
possibly damaging |
Het |
| Rps24 |
A |
G |
14: 24,541,830 (GRCm39) |
T6A |
probably damaging |
Het |
| Ryr2 |
A |
C |
13: 11,760,062 (GRCm39) |
|
probably null |
Het |
| Samd4 |
A |
T |
14: 47,326,532 (GRCm39) |
N454I |
probably damaging |
Het |
| Sap130 |
T |
C |
18: 31,769,135 (GRCm39) |
I32T |
probably benign |
Het |
| Sap30l |
A |
T |
11: 57,696,925 (GRCm39) |
N85I |
probably damaging |
Het |
| Sbf2 |
G |
A |
7: 110,060,353 (GRCm39) |
Q204* |
probably null |
Het |
| Slc45a3 |
T |
C |
1: 131,904,694 (GRCm39) |
W6R |
possibly damaging |
Het |
| Snx16 |
A |
G |
3: 10,484,221 (GRCm39) |
V334A |
probably damaging |
Het |
| Soat1 |
C |
T |
1: 156,269,991 (GRCm39) |
V143I |
probably benign |
Het |
| Sp8 |
T |
A |
12: 118,813,302 (GRCm39) |
F386I |
probably damaging |
Het |
| Spag6 |
C |
T |
2: 18,738,928 (GRCm39) |
S286L |
probably benign |
Het |
| Srpra |
A |
T |
9: 35,124,147 (GRCm39) |
N31I |
possibly damaging |
Het |
| Ssbp4 |
A |
G |
8: 71,051,502 (GRCm39) |
|
probably null |
Het |
| Stxbp2 |
G |
T |
8: 3,684,064 (GRCm39) |
A124S |
probably benign |
Het |
| Tacc2 |
A |
G |
7: 130,343,970 (GRCm39) |
K700R |
probably damaging |
Het |
| Tatdn2 |
A |
T |
6: 113,679,060 (GRCm39) |
|
probably null |
Het |
| Tecrl |
G |
A |
5: 83,439,134 (GRCm39) |
T226I |
probably damaging |
Het |
| Timeless |
T |
G |
10: 128,083,477 (GRCm39) |
V702G |
probably benign |
Het |
| Tjp1 |
A |
T |
7: 64,962,753 (GRCm39) |
S1061R |
probably benign |
Het |
| Tmem39b |
A |
T |
4: 129,587,011 (GRCm39) |
C67S |
probably damaging |
Het |
| Tstd3 |
T |
C |
4: 21,759,475 (GRCm39) |
Y99C |
probably damaging |
Het |
| Ttc39c |
T |
A |
18: 12,817,881 (GRCm39) |
|
probably null |
Het |
| Ttll7 |
C |
T |
3: 146,600,160 (GRCm39) |
P23S |
probably benign |
Het |
| Uba5 |
A |
G |
9: 103,927,107 (GRCm39) |
F290S |
probably damaging |
Het |
| Ubap2l |
T |
C |
3: 89,926,538 (GRCm39) |
Y623C |
probably damaging |
Het |
| Ube3a |
A |
G |
7: 58,925,714 (GRCm39) |
E164G |
probably damaging |
Het |
| Ugcg |
A |
G |
4: 59,207,775 (GRCm39) |
N38S |
probably benign |
Het |
| Ugp2 |
G |
A |
11: 21,279,915 (GRCm39) |
T283I |
probably damaging |
Het |
| Vmn1r55 |
A |
T |
7: 5,149,919 (GRCm39) |
I168N |
probably benign |
Het |
| Wdr27 |
A |
C |
17: 15,112,703 (GRCm39) |
S668A |
probably damaging |
Het |
| Wnt2 |
T |
A |
6: 18,008,696 (GRCm39) |
N247I |
probably damaging |
Het |
| Zfp850 |
A |
T |
7: 27,684,700 (GRCm39) |
C15* |
probably null |
Het |
| Zfp959 |
A |
G |
17: 56,204,677 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Clca3a2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00419:Clca3a2
|
APN |
3 |
144,804,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01019:Clca3a2
|
APN |
3 |
144,519,388 (GRCm39) |
nonsense |
probably null |
|
|
IGL01337:Clca3a2
|
APN |
3 |
144,800,939 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01389:Clca3a2
|
APN |
3 |
144,783,629 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01595:Clca3a2
|
APN |
3 |
144,793,768 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01663:Clca3a2
|
APN |
3 |
144,522,916 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL01704:Clca3a2
|
APN |
3 |
144,800,979 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01779:Clca3a2
|
APN |
3 |
144,525,139 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL02066:Clca3a2
|
APN |
3 |
144,519,216 (GRCm39) |
missense |
probably benign |
|
|
IGL02301:Clca3a2
|
APN |
3 |
144,512,133 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02416:Clca3a2
|
APN |
3 |
144,790,777 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02455:Clca3a2
|
APN |
3 |
144,787,172 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02481:Clca3a2
|
APN |
3 |
144,790,701 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02526:Clca3a2
|
APN |
3 |
144,793,779 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02619:Clca3a2
|
APN |
3 |
144,512,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02797:Clca3a2
|
APN |
3 |
144,787,024 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02852:Clca3a2
|
APN |
3 |
144,512,104 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02901:Clca3a2
|
APN |
3 |
144,522,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03162:Clca3a2
|
APN |
3 |
144,512,177 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03253:Clca3a2
|
APN |
3 |
144,777,324 (GRCm39) |
missense |
probably benign |
0.41 |
|
IGL03256:Clca3a2
|
APN |
3 |
144,792,153 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
IGL03294:Clca3a2
|
APN |
3 |
144,803,530 (GRCm39) |
missense |
probably damaging |
1.00 |
|
3370:Clca3a2
|
UTSW |
3 |
144,783,738 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0032:Clca3a2
|
UTSW |
3 |
144,522,494 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0244:Clca3a2
|
UTSW |
3 |
144,519,659 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0479:Clca3a2
|
UTSW |
3 |
144,796,610 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0542:Clca3a2
|
UTSW |
3 |
144,781,571 (GRCm39) |
splice site |
probably benign |
|
|
R0629:Clca3a2
|
UTSW |
3 |
144,778,000 (GRCm39) |
missense |
probably benign |
|
|
R1249:Clca3a2
|
UTSW |
3 |
144,508,765 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R1370:Clca3a2
|
UTSW |
3 |
144,519,624 (GRCm39) |
splice site |
probably benign |
|
|
R1488:Clca3a2
|
UTSW |
3 |
144,789,925 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1523:Clca3a2
|
UTSW |
3 |
144,777,405 (GRCm39) |
nonsense |
probably null |
|
|
R1568:Clca3a2
|
UTSW |
3 |
144,781,410 (GRCm39) |
nonsense |
probably null |
|
|
R1586:Clca3a2
|
UTSW |
3 |
144,516,477 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1650:Clca3a2
|
UTSW |
3 |
144,797,973 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1776:Clca3a2
|
UTSW |
3 |
144,519,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1797:Clca3a2
|
UTSW |
3 |
144,503,398 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1869:Clca3a2
|
UTSW |
3 |
144,512,164 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1871:Clca3a2
|
UTSW |
3 |
144,503,398 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1919:Clca3a2
|
UTSW |
3 |
144,516,457 (GRCm39) |
missense |
probably benign |
|
|
R1923:Clca3a2
|
UTSW |
3 |
144,511,491 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2101:Clca3a2
|
UTSW |
3 |
144,783,699 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2200:Clca3a2
|
UTSW |
3 |
144,519,685 (GRCm39) |
missense |
probably benign |
0.10 |
|
R2242:Clca3a2
|
UTSW |
3 |
144,796,551 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2324:Clca3a2
|
UTSW |
3 |
144,512,041 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2937:Clca3a2
|
UTSW |
3 |
144,519,679 (GRCm39) |
missense |
probably benign |
0.06 |
|
R3429:Clca3a2
|
UTSW |
3 |
144,512,088 (GRCm39) |
missense |
probably benign |
0.07 |
|
R3434:Clca3a2
|
UTSW |
3 |
144,514,522 (GRCm39) |
unclassified |
probably benign |
|
|
R3551:Clca3a2
|
UTSW |
3 |
144,508,842 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3751:Clca3a2
|
UTSW |
3 |
144,777,216 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3952:Clca3a2
|
UTSW |
3 |
144,508,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4120:Clca3a2
|
UTSW |
3 |
144,516,613 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4383:Clca3a2
|
UTSW |
3 |
144,512,081 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4496:Clca3a2
|
UTSW |
3 |
144,797,926 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4518:Clca3a2
|
UTSW |
3 |
144,514,466 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4598:Clca3a2
|
UTSW |
3 |
144,511,444 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4801:Clca3a2
|
UTSW |
3 |
144,513,112 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4802:Clca3a2
|
UTSW |
3 |
144,513,112 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4816:Clca3a2
|
UTSW |
3 |
144,516,613 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4934:Clca3a2
|
UTSW |
3 |
144,523,692 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4942:Clca3a2
|
UTSW |
3 |
144,512,263 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4962:Clca3a2
|
UTSW |
3 |
144,783,640 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5123:Clca3a2
|
UTSW |
3 |
144,512,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5156:Clca3a2
|
UTSW |
3 |
144,511,599 (GRCm39) |
missense |
probably benign |
0.26 |
|
R5275:Clca3a2
|
UTSW |
3 |
144,519,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5344:Clca3a2
|
UTSW |
3 |
144,793,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5372:Clca3a2
|
UTSW |
3 |
144,503,286 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5424:Clca3a2
|
UTSW |
3 |
144,789,942 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5656:Clca3a2
|
UTSW |
3 |
144,503,393 (GRCm39) |
missense |
probably benign |
0.26 |
|
R5931:Clca3a2
|
UTSW |
3 |
144,797,886 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6059:Clca3a2
|
UTSW |
3 |
144,516,531 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6155:Clca3a2
|
UTSW |
3 |
144,525,118 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6181:Clca3a2
|
UTSW |
3 |
144,796,469 (GRCm39) |
nonsense |
probably null |
|
|
R6254:Clca3a2
|
UTSW |
3 |
144,507,895 (GRCm39) |
missense |
probably benign |
|
|
R6336:Clca3a2
|
UTSW |
3 |
144,512,239 (GRCm39) |
missense |
probably benign |
|
|
R6470:Clca3a2
|
UTSW |
3 |
144,510,024 (GRCm39) |
splice site |
probably null |
|
|
R6593:Clca3a2
|
UTSW |
3 |
144,514,338 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6598:Clca3a2
|
UTSW |
3 |
144,792,246 (GRCm39) |
nonsense |
probably null |
|
|
R6631:Clca3a2
|
UTSW |
3 |
144,519,405 (GRCm39) |
missense |
probably benign |
|
|
R6826:Clca3a2
|
UTSW |
3 |
144,523,815 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6836:Clca3a2
|
UTSW |
3 |
144,512,144 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6896:Clca3a2
|
UTSW |
3 |
144,514,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7167:Clca3a2
|
UTSW |
3 |
144,803,545 (GRCm39) |
missense |
probably benign |
0.40 |
|
R7211:Clca3a2
|
UTSW |
3 |
144,519,775 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7229:Clca3a2
|
UTSW |
3 |
144,789,869 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7256:Clca3a2
|
UTSW |
3 |
144,796,608 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7324:Clca3a2
|
UTSW |
3 |
144,514,372 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7365:Clca3a2
|
UTSW |
3 |
144,804,545 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7411:Clca3a2
|
UTSW |
3 |
144,507,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7486:Clca3a2
|
UTSW |
3 |
144,503,362 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7491:Clca3a2
|
UTSW |
3 |
144,519,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7521:Clca3a2
|
UTSW |
3 |
144,507,674 (GRCm39) |
makesense |
probably null |
|
|
R7813:Clca3a2
|
UTSW |
3 |
144,790,726 (GRCm39) |
missense |
probably benign |
0.26 |
|
R7889:Clca3a2
|
UTSW |
3 |
144,516,574 (GRCm39) |
nonsense |
probably null |
|
|
R7946:Clca3a2
|
UTSW |
3 |
144,513,075 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7991:Clca3a2
|
UTSW |
3 |
144,519,756 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8022:Clca3a2
|
UTSW |
3 |
144,511,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8077:Clca3a2
|
UTSW |
3 |
144,777,288 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R8169:Clca3a2
|
UTSW |
3 |
144,783,653 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8290:Clca3a2
|
UTSW |
3 |
144,793,719 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8300:Clca3a2
|
UTSW |
3 |
144,804,692 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8344:Clca3a2
|
UTSW |
3 |
144,511,703 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8350:Clca3a2
|
UTSW |
3 |
144,783,668 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8367:Clca3a2
|
UTSW |
3 |
144,523,508 (GRCm39) |
splice site |
probably null |
|
|
R8371:Clca3a2
|
UTSW |
3 |
144,513,114 (GRCm39) |
nonsense |
probably null |
|
|
R8814:Clca3a2
|
UTSW |
3 |
144,503,525 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8854:Clca3a2
|
UTSW |
3 |
144,783,852 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8876:Clca3a2
|
UTSW |
3 |
144,777,360 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8887:Clca3a2
|
UTSW |
3 |
144,790,810 (GRCm39) |
nonsense |
probably null |
|
|
R9006:Clca3a2
|
UTSW |
3 |
144,783,789 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9031:Clca3a2
|
UTSW |
3 |
144,511,475 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9069:Clca3a2
|
UTSW |
3 |
144,519,447 (GRCm39) |
splice site |
probably benign |
|
|
R9093:Clca3a2
|
UTSW |
3 |
144,781,481 (GRCm39) |
missense |
probably benign |
0.20 |
|
R9190:Clca3a2
|
UTSW |
3 |
144,796,599 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9201:Clca3a2
|
UTSW |
3 |
144,519,684 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9209:Clca3a2
|
UTSW |
3 |
144,778,005 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9261:Clca3a2
|
UTSW |
3 |
144,525,158 (GRCm39) |
missense |
probably benign |
|
|
R9469:Clca3a2
|
UTSW |
3 |
144,507,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9501:Clca3a2
|
UTSW |
3 |
144,777,322 (GRCm39) |
nonsense |
probably null |
|
|
R9515:Clca3a2
|
UTSW |
3 |
144,508,808 (GRCm39) |
nonsense |
probably null |
|
|
R9569:Clca3a2
|
UTSW |
3 |
144,513,075 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9664:Clca3a2
|
UTSW |
3 |
144,503,575 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0025:Clca3a2
|
UTSW |
3 |
144,792,265 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
Z1177:Clca3a2
|
UTSW |
3 |
144,792,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAGCACATTTCCTTTACGCACGAC -3'
(R):5'- CAATAGTGAAGCCACGCAATGGTG -3'
Sequencing Primer
(F):5'- AGGTTGTCACACTGACCTTAG -3'
(R):5'- tctacctgagaccttatcacaaac -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation