Incidental Mutation 'R1773:Hivep3'
| ID |
196795 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Hivep3
|
| Ensembl Gene |
ENSMUSG00000028634 |
| Gene Name |
human immunodeficiency virus type I enhancer binding protein 3 |
| Synonyms |
Krc, E030045D18Rik, Schnurri-3, Shn3, 2900056N03Rik |
| MMRRC Submission |
039804-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1773 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
119590982-119992608 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 119956034 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Lysine to Isoleucine
at position 1450
(K1450I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000130249
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000106307]
[ENSMUST00000166542]
[ENSMUST00000226560]
|
| AlphaFold |
A2A884 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000106307
AA Change: K1450I
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000101914
Gene: ENSMUSG00000028634
AA Change: K1450I
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
185 |
207 |
1.67e-2 |
SMART |
|
ZnF_C2H2
|
213 |
235 |
8.34e-3 |
SMART |
|
low complexity region
|
257 |
285 |
N/A |
INTRINSIC |
|
low complexity region
|
292 |
323 |
N/A |
INTRINSIC |
|
low complexity region
|
425 |
438 |
N/A |
INTRINSIC |
|
low complexity region
|
513 |
527 |
N/A |
INTRINSIC |
|
low complexity region
|
589 |
612 |
N/A |
INTRINSIC |
|
low complexity region
|
622 |
633 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
636 |
656 |
2.06e1 |
SMART |
|
low complexity region
|
736 |
749 |
N/A |
INTRINSIC |
|
low complexity region
|
806 |
817 |
N/A |
INTRINSIC |
|
low complexity region
|
844 |
865 |
N/A |
INTRINSIC |
|
low complexity region
|
878 |
894 |
N/A |
INTRINSIC |
|
low complexity region
|
896 |
931 |
N/A |
INTRINSIC |
|
low complexity region
|
1010 |
1020 |
N/A |
INTRINSIC |
|
low complexity region
|
1050 |
1061 |
N/A |
INTRINSIC |
|
low complexity region
|
1110 |
1136 |
N/A |
INTRINSIC |
|
low complexity region
|
1143 |
1167 |
N/A |
INTRINSIC |
|
low complexity region
|
1170 |
1183 |
N/A |
INTRINSIC |
|
low complexity region
|
1259 |
1284 |
N/A |
INTRINSIC |
|
low complexity region
|
1376 |
1390 |
N/A |
INTRINSIC |
|
low complexity region
|
1529 |
1547 |
N/A |
INTRINSIC |
|
low complexity region
|
1673 |
1684 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1720 |
1742 |
1.82e-3 |
SMART |
|
ZnF_C2H2
|
1748 |
1772 |
1.69e-3 |
SMART |
|
low complexity region
|
1778 |
1791 |
N/A |
INTRINSIC |
|
low complexity region
|
1814 |
1843 |
N/A |
INTRINSIC |
|
low complexity region
|
2203 |
2216 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000166542
AA Change: K1450I
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000130249
Gene: ENSMUSG00000028634
AA Change: K1450I
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
185 |
207 |
1.67e-2 |
SMART |
|
ZnF_C2H2
|
213 |
235 |
8.34e-3 |
SMART |
|
low complexity region
|
257 |
285 |
N/A |
INTRINSIC |
|
low complexity region
|
292 |
323 |
N/A |
INTRINSIC |
|
low complexity region
|
425 |
438 |
N/A |
INTRINSIC |
|
low complexity region
|
513 |
527 |
N/A |
INTRINSIC |
|
low complexity region
|
589 |
612 |
N/A |
INTRINSIC |
|
low complexity region
|
622 |
633 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
636 |
656 |
2.06e1 |
SMART |
|
low complexity region
|
736 |
749 |
N/A |
INTRINSIC |
|
low complexity region
|
806 |
817 |
N/A |
INTRINSIC |
|
low complexity region
|
844 |
865 |
N/A |
INTRINSIC |
|
low complexity region
|
878 |
894 |
N/A |
INTRINSIC |
|
low complexity region
|
896 |
931 |
N/A |
INTRINSIC |
|
low complexity region
|
1010 |
1020 |
N/A |
INTRINSIC |
|
low complexity region
|
1050 |
1061 |
N/A |
INTRINSIC |
|
low complexity region
|
1110 |
1136 |
N/A |
INTRINSIC |
|
low complexity region
|
1143 |
1167 |
N/A |
INTRINSIC |
|
low complexity region
|
1170 |
1183 |
N/A |
INTRINSIC |
|
low complexity region
|
1259 |
1284 |
N/A |
INTRINSIC |
|
low complexity region
|
1376 |
1390 |
N/A |
INTRINSIC |
|
low complexity region
|
1529 |
1547 |
N/A |
INTRINSIC |
|
low complexity region
|
1673 |
1684 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1720 |
1742 |
1.82e-3 |
SMART |
|
ZnF_C2H2
|
1748 |
1772 |
1.69e-3 |
SMART |
|
low complexity region
|
1778 |
1791 |
N/A |
INTRINSIC |
|
low complexity region
|
1814 |
1843 |
N/A |
INTRINSIC |
|
low complexity region
|
2203 |
2216 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000226560
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.4%
- 20x: 92.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the human immunodeficiency virus type 1 enhancer-binding protein family. Members of this protein family contain multiple zinc finger and acid-rich (ZAS) domains and serine-threonine rich regions. This protein acts as a transcription factor and is able to regulate nuclear factor kappaB-mediated transcription by binding the kappaB motif in target genes. This protein also binds the recombination signal sequence that flanks the V, D, and J regions of immunoglobulin and T-cell receptors. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Sep 2011]
PHENOTYPE: Homozygous mutation of this gene results in diminished IL-2 production by stimulated CD4 cells. Mice homozygous for a knock-out allele exhibit increased bone volume. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 96 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310022A10Rik |
A |
G |
7: 27,280,020 (GRCm39) |
K334E |
probably damaging |
Het |
| Abca12 |
A |
G |
1: 71,327,755 (GRCm39) |
Y1442H |
probably damaging |
Het |
| Acot12 |
A |
G |
13: 91,905,676 (GRCm39) |
T79A |
probably benign |
Het |
| Adipoq |
A |
C |
16: 22,973,988 (GRCm39) |
Q26P |
unknown |
Het |
| Afg2a |
T |
C |
3: 37,493,334 (GRCm39) |
F515L |
probably damaging |
Het |
| Akap13 |
T |
A |
7: 75,333,199 (GRCm39) |
N1582K |
possibly damaging |
Het |
| Alg9 |
A |
G |
9: 50,690,396 (GRCm39) |
T133A |
probably benign |
Het |
| Anks3 |
T |
C |
16: 4,765,158 (GRCm39) |
T418A |
probably benign |
Het |
| Ano3 |
A |
C |
2: 110,591,800 (GRCm39) |
L37R |
probably damaging |
Het |
| Ano9 |
A |
G |
7: 140,688,291 (GRCm39) |
F178L |
possibly damaging |
Het |
| Arhgef12 |
A |
G |
9: 42,916,838 (GRCm39) |
|
probably null |
Het |
| Arl16 |
T |
A |
11: 120,356,589 (GRCm39) |
I137F |
possibly damaging |
Het |
| Brpf1 |
T |
A |
6: 113,296,892 (GRCm39) |
S959T |
possibly damaging |
Het |
| Ccdc27 |
C |
T |
4: 154,126,222 (GRCm39) |
R89Q |
unknown |
Het |
| Cd109 |
A |
C |
9: 78,611,006 (GRCm39) |
Q1207H |
probably benign |
Het |
| Cd14 |
A |
T |
18: 36,858,357 (GRCm39) |
V366D |
possibly damaging |
Het |
| Cep290 |
G |
A |
10: 100,346,435 (GRCm39) |
V538I |
probably benign |
Het |
| Cep57 |
G |
A |
9: 13,727,364 (GRCm39) |
A202V |
probably damaging |
Het |
| Chl1 |
T |
C |
6: 103,624,292 (GRCm39) |
|
probably null |
Het |
| Cmah |
T |
G |
13: 24,601,282 (GRCm39) |
F29L |
probably benign |
Het |
| Cracd |
G |
T |
5: 77,015,052 (GRCm39) |
A42S |
possibly damaging |
Het |
| Crybg1 |
A |
G |
10: 43,868,544 (GRCm39) |
V1378A |
possibly damaging |
Het |
| Cryzl2 |
A |
G |
1: 157,298,292 (GRCm39) |
K227R |
probably benign |
Het |
| D130043K22Rik |
T |
G |
13: 25,066,585 (GRCm39) |
V794G |
possibly damaging |
Het |
| Ddx4 |
T |
A |
13: 112,736,436 (GRCm39) |
T645S |
probably benign |
Het |
| Dhcr7 |
C |
T |
7: 143,401,195 (GRCm39) |
R453C |
possibly damaging |
Het |
| Dhx8 |
T |
C |
11: 101,643,189 (GRCm39) |
Y754H |
possibly damaging |
Het |
| Dip2b |
T |
A |
15: 100,091,842 (GRCm39) |
D860E |
probably benign |
Het |
| Dnah7a |
T |
C |
1: 53,472,046 (GRCm39) |
|
probably null |
Het |
| Dst |
A |
G |
1: 34,330,980 (GRCm39) |
D6937G |
probably damaging |
Het |
| Dusp1 |
A |
G |
17: 26,726,081 (GRCm39) |
I204T |
probably damaging |
Het |
| Dync2h1 |
T |
A |
9: 7,128,256 (GRCm39) |
Q1859L |
probably damaging |
Het |
| E4f1 |
C |
A |
17: 24,665,558 (GRCm39) |
G328V |
probably damaging |
Het |
| Eml5 |
T |
C |
12: 98,765,098 (GRCm39) |
Y1617C |
probably damaging |
Het |
| Espn |
G |
T |
4: 152,212,686 (GRCm39) |
P622Q |
probably damaging |
Het |
| Fam184b |
G |
A |
5: 45,741,676 (GRCm39) |
P185L |
possibly damaging |
Het |
| Fn1 |
T |
A |
1: 71,676,542 (GRCm39) |
D563V |
probably damaging |
Het |
| Gad2 |
A |
G |
2: 22,580,219 (GRCm39) |
Y540C |
probably benign |
Het |
| Garin1b |
T |
C |
6: 29,334,152 (GRCm39) |
S335P |
possibly damaging |
Het |
| Gdf11 |
T |
C |
10: 128,727,163 (GRCm39) |
D131G |
probably damaging |
Het |
| Gm19965 |
T |
A |
1: 116,748,989 (GRCm39) |
Y223* |
probably null |
Het |
| H2-M10.6 |
A |
G |
17: 37,123,076 (GRCm39) |
K3R |
probably benign |
Het |
| Hid1 |
A |
G |
11: 115,239,336 (GRCm39) |
Y776H |
probably damaging |
Het |
| Icam5 |
T |
C |
9: 20,944,821 (GRCm39) |
L128P |
possibly damaging |
Het |
| Idnk |
T |
C |
13: 58,305,526 (GRCm39) |
V9A |
probably damaging |
Het |
| Il4ra |
A |
T |
7: 125,166,354 (GRCm39) |
T33S |
possibly damaging |
Het |
| Ino80 |
A |
G |
2: 119,248,890 (GRCm39) |
V990A |
probably benign |
Het |
| Krtap4-9 |
T |
C |
11: 99,676,396 (GRCm39) |
|
probably benign |
Het |
| Lrrk2 |
A |
G |
15: 91,664,184 (GRCm39) |
I1974V |
possibly damaging |
Het |
| Mcm3ap |
C |
T |
10: 76,306,994 (GRCm39) |
A369V |
probably benign |
Het |
| Nek6 |
A |
G |
2: 38,472,431 (GRCm39) |
M252V |
probably benign |
Het |
| Nfasc |
T |
A |
1: 132,538,577 (GRCm39) |
I443F |
probably damaging |
Het |
| Nme8 |
T |
G |
13: 19,881,206 (GRCm39) |
M1L |
probably damaging |
Het |
| Npnt |
T |
A |
3: 132,610,454 (GRCm39) |
Q423L |
possibly damaging |
Het |
| Nup133 |
A |
T |
8: 124,657,722 (GRCm39) |
C404* |
probably null |
Het |
| Or2b7 |
T |
C |
13: 21,739,982 (GRCm39) |
D70G |
probably damaging |
Het |
| Or4c124 |
A |
G |
2: 89,156,086 (GRCm39) |
V146A |
probably benign |
Het |
| Or4f14b |
A |
G |
2: 111,775,204 (GRCm39) |
V199A |
possibly damaging |
Het |
| Or56a4 |
T |
C |
7: 104,806,190 (GRCm39) |
E233G |
probably benign |
Het |
| Or5an1c |
T |
C |
19: 12,219,023 (GRCm39) |
M1V |
probably null |
Het |
| Or6c213 |
A |
G |
10: 129,574,312 (GRCm39) |
L158S |
probably damaging |
Het |
| Otog |
T |
A |
7: 45,937,583 (GRCm39) |
I1764N |
probably benign |
Het |
| Oxa1l |
A |
G |
14: 54,600,909 (GRCm39) |
I127M |
probably benign |
Het |
| P4hb |
C |
A |
11: 120,463,552 (GRCm39) |
V28F |
probably damaging |
Het |
| Pbld2 |
C |
T |
10: 62,890,150 (GRCm39) |
A186V |
probably benign |
Het |
| Pdzph1 |
G |
T |
17: 59,281,808 (GRCm39) |
T158K |
probably damaging |
Het |
| Pgm2 |
T |
A |
5: 64,265,194 (GRCm39) |
|
probably null |
Het |
| Phip |
A |
T |
9: 82,758,242 (GRCm39) |
S1484T |
probably benign |
Het |
| Pikfyve |
T |
C |
1: 65,231,430 (GRCm39) |
L100P |
probably damaging |
Het |
| Pikfyve |
T |
C |
1: 65,285,529 (GRCm39) |
S923P |
probably benign |
Het |
| Pla2g4e |
A |
G |
2: 120,075,202 (GRCm39) |
S63P |
probably benign |
Het |
| Plekhh2 |
A |
G |
17: 84,906,693 (GRCm39) |
E1176G |
probably damaging |
Het |
| Prlr |
T |
A |
15: 10,325,404 (GRCm39) |
Y192* |
probably null |
Het |
| Pten |
T |
A |
19: 32,775,472 (GRCm39) |
C71S |
probably damaging |
Het |
| Rbbp8nl |
A |
G |
2: 179,922,987 (GRCm39) |
L202P |
probably benign |
Het |
| Ripor2 |
T |
A |
13: 24,885,237 (GRCm39) |
S491T |
probably benign |
Het |
| Robo1 |
A |
T |
16: 72,801,399 (GRCm39) |
I1008F |
probably benign |
Het |
| Scg2 |
T |
C |
1: 79,413,352 (GRCm39) |
N417S |
probably benign |
Het |
| Scn8a |
A |
G |
15: 100,937,496 (GRCm39) |
I1581V |
probably damaging |
Het |
| Slc22a8 |
T |
A |
19: 8,571,593 (GRCm39) |
I108N |
probably damaging |
Het |
| Slc9a8 |
A |
T |
2: 167,313,385 (GRCm39) |
T416S |
possibly damaging |
Het |
| Spata32 |
T |
A |
11: 103,099,644 (GRCm39) |
E287V |
probably damaging |
Het |
| Tgfbrap1 |
C |
T |
1: 43,114,512 (GRCm39) |
G196D |
probably damaging |
Het |
| Tgm5 |
G |
T |
2: 120,908,131 (GRCm39) |
T15K |
possibly damaging |
Het |
| Tmc1 |
C |
T |
19: 20,803,865 (GRCm39) |
|
probably null |
Het |
| Tmem177 |
T |
C |
1: 119,838,306 (GRCm39) |
I124M |
possibly damaging |
Het |
| Trim30a |
A |
G |
7: 104,085,108 (GRCm39) |
F34S |
probably damaging |
Het |
| Tsn |
T |
C |
1: 118,232,969 (GRCm39) |
T112A |
probably benign |
Het |
| Tspyl5 |
T |
G |
15: 33,686,922 (GRCm39) |
N341T |
probably benign |
Het |
| Vmn2r108 |
C |
T |
17: 20,689,335 (GRCm39) |
C540Y |
probably damaging |
Het |
| Vrtn |
C |
T |
12: 84,696,998 (GRCm39) |
R583W |
probably damaging |
Het |
| Wnt1 |
T |
C |
15: 98,689,638 (GRCm39) |
S142P |
probably damaging |
Het |
| Wrn |
A |
T |
8: 33,833,589 (GRCm39) |
I108N |
probably damaging |
Het |
| Zfhx2 |
A |
C |
14: 55,310,348 (GRCm39) |
C733G |
possibly damaging |
Het |
| Zfp219 |
T |
C |
14: 52,244,563 (GRCm39) |
T539A |
probably damaging |
Het |
| Zswim8 |
T |
A |
14: 20,761,598 (GRCm39) |
M177K |
probably damaging |
Het |
|
| Other mutations in Hivep3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00953:Hivep3
|
APN |
4 |
119,955,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01017:Hivep3
|
APN |
4 |
119,956,443 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01837:Hivep3
|
APN |
4 |
119,951,759 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL01878:Hivep3
|
APN |
4 |
119,952,424 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL02134:Hivep3
|
APN |
4 |
119,990,771 (GRCm39) |
splice site |
probably benign |
|
|
IGL02183:Hivep3
|
APN |
4 |
119,989,221 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02350:Hivep3
|
APN |
4 |
119,980,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02451:Hivep3
|
APN |
4 |
119,991,162 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02567:Hivep3
|
APN |
4 |
119,991,153 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02617:Hivep3
|
APN |
4 |
119,952,641 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02725:Hivep3
|
APN |
4 |
119,953,019 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL02828:Hivep3
|
APN |
4 |
119,954,929 (GRCm39) |
nonsense |
probably null |
|
|
IGL02954:Hivep3
|
APN |
4 |
119,990,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02966:Hivep3
|
APN |
4 |
119,989,383 (GRCm39) |
missense |
probably benign |
0.04 |
|
Branchial
|
UTSW |
4 |
119,953,772 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
Deceit
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
Mandible
|
UTSW |
4 |
119,954,318 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Sclerotic
|
UTSW |
4 |
119,952,296 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
Stealth
|
UTSW |
4 |
119,980,073 (GRCm39) |
nonsense |
probably null |
|
|
Yellowjacket
|
UTSW |
4 |
119,989,554 (GRCm39) |
missense |
probably benign |
0.01 |
|
PIT4260001:Hivep3
|
UTSW |
4 |
119,956,379 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0321:Hivep3
|
UTSW |
4 |
119,952,788 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0336:Hivep3
|
UTSW |
4 |
119,961,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0558:Hivep3
|
UTSW |
4 |
119,953,763 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0562:Hivep3
|
UTSW |
4 |
119,953,751 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0637:Hivep3
|
UTSW |
4 |
119,989,738 (GRCm39) |
nonsense |
probably null |
|
|
R0645:Hivep3
|
UTSW |
4 |
119,954,531 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1186:Hivep3
|
UTSW |
4 |
119,671,920 (GRCm39) |
start gained |
probably benign |
|
|
R1254:Hivep3
|
UTSW |
4 |
119,956,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1428:Hivep3
|
UTSW |
4 |
119,953,772 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1623:Hivep3
|
UTSW |
4 |
119,952,901 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R1739:Hivep3
|
UTSW |
4 |
119,952,371 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1766:Hivep3
|
UTSW |
4 |
119,953,868 (GRCm39) |
missense |
probably benign |
|
|
R1769:Hivep3
|
UTSW |
4 |
119,954,768 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1968:Hivep3
|
UTSW |
4 |
119,953,435 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R2220:Hivep3
|
UTSW |
4 |
119,591,235 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2428:Hivep3
|
UTSW |
4 |
119,955,705 (GRCm39) |
nonsense |
probably null |
|
|
R3789:Hivep3
|
UTSW |
4 |
119,955,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3917:Hivep3
|
UTSW |
4 |
119,956,624 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4366:Hivep3
|
UTSW |
4 |
119,953,286 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4436:Hivep3
|
UTSW |
4 |
119,953,120 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4504:Hivep3
|
UTSW |
4 |
119,590,990 (GRCm39) |
unclassified |
probably benign |
|
|
R4705:Hivep3
|
UTSW |
4 |
119,729,247 (GRCm39) |
intron |
probably benign |
|
|
R4713:Hivep3
|
UTSW |
4 |
119,989,000 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4756:Hivep3
|
UTSW |
4 |
119,955,020 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4887:Hivep3
|
UTSW |
4 |
119,980,131 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4888:Hivep3
|
UTSW |
4 |
119,980,131 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5008:Hivep3
|
UTSW |
4 |
119,956,114 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5204:Hivep3
|
UTSW |
4 |
119,961,053 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5594:Hivep3
|
UTSW |
4 |
119,980,245 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5697:Hivep3
|
UTSW |
4 |
119,954,152 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R5715:Hivep3
|
UTSW |
4 |
119,953,570 (GRCm39) |
missense |
probably benign |
|
|
R5740:Hivep3
|
UTSW |
4 |
119,953,220 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5760:Hivep3
|
UTSW |
4 |
119,952,208 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5923:Hivep3
|
UTSW |
4 |
119,953,490 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5927:Hivep3
|
UTSW |
4 |
119,954,305 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6042:Hivep3
|
UTSW |
4 |
119,955,061 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6074:Hivep3
|
UTSW |
4 |
119,954,891 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6150:Hivep3
|
UTSW |
4 |
119,591,274 (GRCm39) |
nonsense |
probably null |
|
|
R6211:Hivep3
|
UTSW |
4 |
119,955,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6251:Hivep3
|
UTSW |
4 |
119,952,137 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6451:Hivep3
|
UTSW |
4 |
119,956,105 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6531:Hivep3
|
UTSW |
4 |
119,980,073 (GRCm39) |
nonsense |
probably null |
|
|
R6651:Hivep3
|
UTSW |
4 |
119,980,146 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6701:Hivep3
|
UTSW |
4 |
119,951,737 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6721:Hivep3
|
UTSW |
4 |
119,952,296 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R6796:Hivep3
|
UTSW |
4 |
119,953,558 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6864:Hivep3
|
UTSW |
4 |
119,952,085 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R6902:Hivep3
|
UTSW |
4 |
119,953,192 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R7111:Hivep3
|
UTSW |
4 |
119,952,431 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R7113:Hivep3
|
UTSW |
4 |
119,955,566 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7140:Hivep3
|
UTSW |
4 |
119,954,318 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7189:Hivep3
|
UTSW |
4 |
119,989,416 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7218:Hivep3
|
UTSW |
4 |
119,952,649 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7366:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7368:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7491:Hivep3
|
UTSW |
4 |
119,956,027 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7496:Hivep3
|
UTSW |
4 |
119,989,599 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7514:Hivep3
|
UTSW |
4 |
119,954,052 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R7604:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7605:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7607:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7610:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7611:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7613:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7626:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7707:Hivep3
|
UTSW |
4 |
119,591,156 (GRCm39) |
missense |
|
|
|
R7736:Hivep3
|
UTSW |
4 |
119,952,740 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7915:Hivep3
|
UTSW |
4 |
119,954,962 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7943:Hivep3
|
UTSW |
4 |
119,989,554 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7972:Hivep3
|
UTSW |
4 |
119,954,711 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8093:Hivep3
|
UTSW |
4 |
119,952,632 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R8111:Hivep3
|
UTSW |
4 |
119,955,583 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8215:Hivep3
|
UTSW |
4 |
119,980,098 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8364:Hivep3
|
UTSW |
4 |
119,956,639 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8467:Hivep3
|
UTSW |
4 |
119,952,238 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8768:Hivep3
|
UTSW |
4 |
119,989,521 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8890:Hivep3
|
UTSW |
4 |
119,953,657 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8902:Hivep3
|
UTSW |
4 |
119,953,937 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9022:Hivep3
|
UTSW |
4 |
119,955,304 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9336:Hivep3
|
UTSW |
4 |
119,952,400 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R9606:Hivep3
|
UTSW |
4 |
119,989,786 (GRCm39) |
missense |
probably damaging |
0.98 |
|
RF019:Hivep3
|
UTSW |
4 |
119,955,467 (GRCm39) |
missense |
probably benign |
0.12 |
|
X0062:Hivep3
|
UTSW |
4 |
119,955,895 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0067:Hivep3
|
UTSW |
4 |
119,988,984 (GRCm39) |
missense |
probably damaging |
0.96 |
|
Z1176:Hivep3
|
UTSW |
4 |
119,990,979 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Hivep3
|
UTSW |
4 |
119,988,975 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Hivep3
|
UTSW |
4 |
119,953,143 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATCCACAGCCAGTGGAAGCAAG -3'
(R):5'- GCAGTACCTTCTTTGAGTCCGTACC -3'
Sequencing Primer
(F):5'- AAGCAAGCGCGTCCTTTC -3'
(R):5'- CTTTACACTCATTGGAGGCAGAC -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation