Incidental Mutation 'R1778:Ddx60'
| ID |
197242 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ddx60
|
| Ensembl Gene |
ENSMUSG00000037921 |
| Gene Name |
DExD/H box helicase 60 |
| Synonyms |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| MMRRC Submission |
039809-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.199)
|
| Stock # |
R1778 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
8 |
| Chromosomal Location |
62381121-62490735 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 62427210 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Valine
at position 762
(I762V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000091197
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000070631]
[ENSMUST00000093485]
|
| AlphaFold |
E9PZQ1 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000070631
AA Change: I761V
PolyPhen 2
Score 0.851 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000070741
Gene: ENSMUSG00000037921
AA Change: I761V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
99 |
110 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
376 |
N/A |
INTRINSIC |
|
DEXDc
|
758 |
949 |
1.05e-15 |
SMART |
|
Blast:DEXDc
|
1007 |
1132 |
4e-24 |
BLAST |
|
HELICc
|
1245 |
1328 |
4.35e-13 |
SMART |
|
low complexity region
|
1362 |
1373 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
1503 |
1584 |
1e-20 |
BLAST |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000093485
AA Change: I762V
PolyPhen 2
Score 0.851 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000091197
Gene: ENSMUSG00000037921
AA Change: I762V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
99 |
110 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
376 |
N/A |
INTRINSIC |
|
DEXDc
|
759 |
950 |
1.05e-15 |
SMART |
|
Blast:DEXDc
|
1008 |
1133 |
4e-24 |
BLAST |
|
HELICc
|
1246 |
1329 |
4.35e-13 |
SMART |
|
low complexity region
|
1363 |
1374 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
1504 |
1585 |
1e-20 |
BLAST |
|
| Meta Mutation Damage Score |
0.2177 |
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 97.0%
- 10x: 95.6%
- 20x: 93.3%
|
| Validation Efficiency |
98% (107/109) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal immunity to several viruses (IAV, EMCV, SINV) but increased susceptibility to VSV infection. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 105 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930432E11Rik |
T |
C |
7: 29,260,131 (GRCm39) |
|
noncoding transcript |
Het |
| 4930568D16Rik |
A |
G |
2: 35,244,995 (GRCm39) |
M119T |
probably damaging |
Het |
| Aadacl2 |
A |
G |
3: 59,924,871 (GRCm39) |
|
probably null |
Het |
| Abca9 |
C |
T |
11: 110,021,542 (GRCm39) |
W1056* |
probably null |
Het |
| Adam20 |
A |
C |
8: 41,249,698 (GRCm39) |
T603P |
possibly damaging |
Het |
| Adgrl1 |
T |
C |
8: 84,656,666 (GRCm39) |
L323P |
probably damaging |
Het |
| Afap1l2 |
C |
T |
19: 56,904,638 (GRCm39) |
E628K |
possibly damaging |
Het |
| Ahctf1 |
A |
T |
1: 179,580,580 (GRCm39) |
L1874Q |
possibly damaging |
Het |
| Ak8 |
A |
G |
2: 28,602,333 (GRCm39) |
E89G |
probably benign |
Het |
| Aldh16a1 |
G |
A |
7: 44,796,732 (GRCm39) |
R256C |
probably damaging |
Het |
| Anxa5 |
G |
A |
3: 36,519,480 (GRCm39) |
T3M |
probably damaging |
Het |
| Arhgef16 |
T |
C |
4: 154,372,443 (GRCm39) |
K210E |
probably benign |
Het |
| Baz2b |
T |
C |
2: 59,836,480 (GRCm39) |
T18A |
unknown |
Het |
| Bub1 |
A |
C |
2: 127,645,042 (GRCm39) |
I960M |
possibly damaging |
Het |
| Cbln2 |
G |
T |
18: 86,731,272 (GRCm39) |
D27Y |
probably benign |
Het |
| Ces2h |
C |
A |
8: 105,741,239 (GRCm39) |
P77Q |
possibly damaging |
Het |
| Cfap410 |
G |
T |
10: 77,818,778 (GRCm39) |
A150S |
probably benign |
Het |
| Chga |
T |
A |
12: 102,527,959 (GRCm39) |
M150K |
probably benign |
Het |
| Chmp3 |
A |
G |
6: 71,554,791 (GRCm39) |
E162G |
probably benign |
Het |
| Clip3 |
A |
G |
7: 29,996,861 (GRCm39) |
N161S |
probably damaging |
Het |
| Col12a1 |
T |
A |
9: 79,511,867 (GRCm39) |
|
probably benign |
Het |
| Cuedc2 |
C |
T |
19: 46,320,079 (GRCm39) |
G105D |
probably benign |
Het |
| Cyp2j7 |
A |
C |
4: 96,087,627 (GRCm39) |
F428V |
probably damaging |
Het |
| Def6 |
G |
A |
17: 28,439,160 (GRCm39) |
R257Q |
probably benign |
Het |
| Dkkl1 |
A |
T |
7: 44,860,819 (GRCm39) |
|
probably null |
Het |
| Dnah3 |
A |
G |
7: 119,677,625 (GRCm39) |
L433P |
probably damaging |
Het |
| Eif2s3y |
C |
T |
Y: 1,011,287 (GRCm39) |
R33C |
probably benign |
Het |
| Elavl2 |
T |
A |
4: 91,141,715 (GRCm39) |
Y269F |
probably damaging |
Het |
| Esco2 |
A |
G |
14: 66,068,711 (GRCm39) |
S200P |
possibly damaging |
Het |
| Fcrl1 |
T |
A |
3: 87,292,626 (GRCm39) |
|
probably benign |
Het |
| Fhod1 |
C |
A |
8: 106,056,309 (GRCm39) |
D1135Y |
probably damaging |
Het |
| Fnbp1l |
T |
C |
3: 122,383,796 (GRCm39) |
N41D |
possibly damaging |
Het |
| Folh1 |
A |
T |
7: 86,410,907 (GRCm39) |
|
probably null |
Het |
| Fpr-rs7 |
T |
C |
17: 20,334,277 (GRCm39) |
D71G |
probably damaging |
Het |
| Gm10271 |
A |
G |
10: 116,797,844 (GRCm39) |
|
probably benign |
Het |
| Gm4841 |
A |
T |
18: 60,404,020 (GRCm39) |
Y24* |
probably null |
Het |
| Greb1 |
G |
A |
12: 16,740,895 (GRCm39) |
R1396C |
probably benign |
Het |
| Hectd1 |
C |
T |
12: 51,800,590 (GRCm39) |
C2076Y |
probably damaging |
Het |
| Hnrnpu |
A |
G |
1: 178,152,806 (GRCm39) |
|
probably benign |
Het |
| Ice2 |
T |
C |
9: 69,322,930 (GRCm39) |
I475T |
probably benign |
Het |
| Ifit1bl1 |
T |
A |
19: 34,571,593 (GRCm39) |
Q288L |
probably damaging |
Het |
| Ift56 |
T |
A |
6: 38,386,411 (GRCm39) |
D377E |
possibly damaging |
Het |
| Ik |
T |
C |
18: 36,889,871 (GRCm39) |
|
probably benign |
Het |
| Kidins220 |
C |
T |
12: 25,063,445 (GRCm39) |
|
probably benign |
Het |
| Kmt2c |
T |
C |
5: 25,577,972 (GRCm39) |
D768G |
probably benign |
Het |
| Kmt2e |
A |
G |
5: 23,697,362 (GRCm39) |
T87A |
probably damaging |
Het |
| Lama5 |
G |
A |
2: 179,837,274 (GRCm39) |
|
probably benign |
Het |
| Lmbr1l |
A |
G |
15: 98,810,357 (GRCm39) |
S85P |
probably damaging |
Het |
| Lrig2 |
A |
G |
3: 104,374,682 (GRCm39) |
|
probably benign |
Het |
| Lrig3 |
A |
G |
10: 125,845,944 (GRCm39) |
D791G |
probably damaging |
Het |
| Lrrc2 |
G |
A |
9: 110,809,908 (GRCm39) |
V315M |
probably benign |
Het |
| Lrrc4b |
A |
G |
7: 44,111,823 (GRCm39) |
D565G |
probably benign |
Het |
| Mpped1 |
C |
T |
15: 83,676,191 (GRCm39) |
|
probably benign |
Het |
| Msrb2 |
T |
A |
2: 19,388,114 (GRCm39) |
D87E |
probably benign |
Het |
| Muc20 |
T |
C |
16: 32,614,511 (GRCm39) |
T289A |
possibly damaging |
Het |
| Myo15a |
C |
A |
11: 60,369,238 (GRCm39) |
P666Q |
possibly damaging |
Het |
| Nfat5 |
C |
T |
8: 108,088,421 (GRCm39) |
P579L |
probably damaging |
Het |
| Nipbl |
A |
C |
15: 8,348,972 (GRCm39) |
M1920R |
probably damaging |
Het |
| Nuak1 |
T |
C |
10: 84,210,738 (GRCm39) |
|
probably null |
Het |
| Nup210l |
A |
G |
3: 90,096,793 (GRCm39) |
E1334G |
probably damaging |
Het |
| Odad2 |
A |
T |
18: 7,127,388 (GRCm39) |
C942S |
probably damaging |
Het |
| Or52e8b |
A |
T |
7: 104,673,370 (GRCm39) |
N272K |
probably benign |
Het |
| Or5an1c |
T |
A |
19: 12,218,819 (GRCm39) |
I69F |
probably benign |
Het |
| Or6c6c |
T |
C |
10: 129,541,574 (GRCm39) |
Y276H |
probably benign |
Het |
| Or9s13 |
G |
A |
1: 92,548,342 (GRCm39) |
G238E |
possibly damaging |
Het |
| Or9s14 |
A |
T |
1: 92,535,831 (GRCm39) |
N91Y |
possibly damaging |
Het |
| P4ha3 |
A |
T |
7: 99,949,898 (GRCm39) |
|
probably null |
Het |
| Pbld2 |
C |
T |
10: 62,890,150 (GRCm39) |
A186V |
probably benign |
Het |
| Pcdh18 |
A |
T |
3: 49,710,083 (GRCm39) |
Y411N |
probably benign |
Het |
| Pgf |
A |
G |
12: 85,218,541 (GRCm39) |
S70P |
probably benign |
Het |
| Phrf1 |
T |
A |
7: 140,812,369 (GRCm39) |
D44E |
probably benign |
Het |
| Pla2g4a |
A |
G |
1: 149,778,196 (GRCm39) |
|
probably benign |
Het |
| Plce1 |
A |
G |
19: 38,769,234 (GRCm39) |
|
probably benign |
Het |
| Plxna2 |
A |
G |
1: 194,493,278 (GRCm39) |
N1851S |
probably benign |
Het |
| Prl7a2 |
G |
A |
13: 27,843,254 (GRCm39) |
T183I |
probably damaging |
Het |
| Prxl2b |
A |
T |
4: 154,981,814 (GRCm39) |
V151D |
probably damaging |
Het |
| Ptger4 |
A |
T |
15: 5,264,576 (GRCm39) |
L335H |
probably damaging |
Het |
| Ptgr1 |
A |
G |
4: 58,984,865 (GRCm39) |
|
probably benign |
Het |
| Rdh7 |
A |
G |
10: 127,720,590 (GRCm39) |
S261P |
probably benign |
Het |
| Reg3a |
A |
G |
6: 78,360,269 (GRCm39) |
T150A |
probably benign |
Het |
| Rnf111 |
A |
G |
9: 70,383,394 (GRCm39) |
S180P |
probably benign |
Het |
| Rnf17 |
A |
G |
14: 56,759,856 (GRCm39) |
M1554V |
probably damaging |
Het |
| Rnf215 |
T |
A |
11: 4,085,873 (GRCm39) |
Y117* |
probably null |
Het |
| Rnps1-ps |
A |
T |
6: 7,983,124 (GRCm39) |
|
noncoding transcript |
Het |
| Rogdi |
T |
C |
16: 4,828,369 (GRCm39) |
T165A |
probably benign |
Het |
| Rpe65 |
A |
G |
3: 159,328,485 (GRCm39) |
Y431C |
probably damaging |
Het |
| Scube1 |
A |
G |
15: 83,494,405 (GRCm39) |
F844S |
probably damaging |
Het |
| Sdr16c6 |
T |
A |
4: 4,058,814 (GRCm39) |
E257D |
probably benign |
Het |
| Sim1 |
C |
A |
10: 50,857,649 (GRCm39) |
C466* |
probably null |
Het |
| Spi1 |
T |
A |
2: 90,929,867 (GRCm39) |
H46Q |
probably damaging |
Het |
| Sumf2 |
C |
A |
5: 129,873,909 (GRCm39) |
|
probably benign |
Het |
| Tbcb |
A |
G |
7: 29,931,037 (GRCm39) |
Y28H |
probably benign |
Het |
| Tecta |
C |
T |
9: 42,254,927 (GRCm39) |
C1752Y |
probably damaging |
Het |
| Tep1 |
T |
C |
14: 51,067,079 (GRCm39) |
|
probably benign |
Het |
| Tmem245 |
A |
T |
4: 56,903,968 (GRCm39) |
W591R |
probably damaging |
Het |
| Tnxb |
A |
G |
17: 34,902,548 (GRCm39) |
I1134V |
probably benign |
Het |
| Trappc14 |
T |
C |
5: 138,260,739 (GRCm39) |
|
probably null |
Het |
| Trim13 |
G |
T |
14: 61,843,068 (GRCm39) |
A362S |
probably benign |
Het |
| Trim47 |
T |
A |
11: 116,000,646 (GRCm39) |
D134V |
probably damaging |
Het |
| Utrn |
C |
A |
10: 12,312,108 (GRCm39) |
D616Y |
probably damaging |
Het |
| Vnn1 |
G |
T |
10: 23,775,415 (GRCm39) |
A222S |
possibly damaging |
Het |
| Wdr17 |
A |
G |
8: 55,143,249 (GRCm39) |
W110R |
probably damaging |
Het |
| Wwp1 |
G |
T |
4: 19,627,892 (GRCm39) |
Y700* |
probably null |
Het |
| Zbtb21 |
T |
C |
16: 97,751,785 (GRCm39) |
S661G |
probably benign |
Het |
| Zfp955b |
A |
G |
17: 33,521,788 (GRCm39) |
K419R |
probably benign |
Het |
|
| Other mutations in Ddx60 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00340:Ddx60
|
APN |
8 |
62,411,680 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00915:Ddx60
|
APN |
8 |
62,440,465 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL00931:Ddx60
|
APN |
8 |
62,422,617 (GRCm39) |
missense |
probably benign |
0.18 |
|
IGL01023:Ddx60
|
APN |
8 |
62,395,548 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01313:Ddx60
|
APN |
8 |
62,435,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01615:Ddx60
|
APN |
8 |
62,416,774 (GRCm39) |
missense |
probably null |
0.81 |
|
IGL01733:Ddx60
|
APN |
8 |
62,436,899 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01779:Ddx60
|
APN |
8 |
62,470,857 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01900:Ddx60
|
APN |
8 |
62,453,743 (GRCm39) |
splice site |
probably benign |
|
|
IGL02110:Ddx60
|
APN |
8 |
62,470,281 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02302:Ddx60
|
APN |
8 |
62,428,866 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02468:Ddx60
|
APN |
8 |
62,411,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02569:Ddx60
|
APN |
8 |
62,477,985 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL02622:Ddx60
|
APN |
8 |
62,395,470 (GRCm39) |
splice site |
probably null |
|
|
IGL02657:Ddx60
|
APN |
8 |
62,437,149 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02677:Ddx60
|
APN |
8 |
62,441,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02701:Ddx60
|
APN |
8 |
62,432,375 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02806:Ddx60
|
APN |
8 |
62,409,156 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03137:Ddx60
|
APN |
8 |
62,441,117 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
IGL03295:Ddx60
|
APN |
8 |
62,409,155 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL03387:Ddx60
|
APN |
8 |
62,465,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03411:Ddx60
|
APN |
8 |
62,430,916 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Scatter
|
UTSW |
8 |
62,474,348 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
shotgun
|
UTSW |
8 |
62,490,101 (GRCm39) |
missense |
probably benign |
0.28 |
|
splay
|
UTSW |
8 |
62,474,343 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
G1Funyon:Ddx60
|
UTSW |
8 |
62,453,631 (GRCm39) |
missense |
probably benign |
0.01 |
|
PIT4504001:Ddx60
|
UTSW |
8 |
62,411,147 (GRCm39) |
missense |
probably benign |
|
|
PIT4677001:Ddx60
|
UTSW |
8 |
62,425,288 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0090:Ddx60
|
UTSW |
8 |
62,395,327 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0266:Ddx60
|
UTSW |
8 |
62,486,527 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0325:Ddx60
|
UTSW |
8 |
62,436,889 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0367:Ddx60
|
UTSW |
8 |
62,470,783 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R0403:Ddx60
|
UTSW |
8 |
62,447,575 (GRCm39) |
splice site |
probably benign |
|
|
R0479:Ddx60
|
UTSW |
8 |
62,422,691 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0561:Ddx60
|
UTSW |
8 |
62,470,828 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0844:Ddx60
|
UTSW |
8 |
62,440,395 (GRCm39) |
missense |
probably benign |
0.27 |
|
R1119:Ddx60
|
UTSW |
8 |
62,395,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1428:Ddx60
|
UTSW |
8 |
62,411,193 (GRCm39) |
splice site |
probably benign |
|
|
R1840:Ddx60
|
UTSW |
8 |
62,422,587 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1964:Ddx60
|
UTSW |
8 |
62,401,903 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1970:Ddx60
|
UTSW |
8 |
62,425,240 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2101:Ddx60
|
UTSW |
8 |
62,393,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2174:Ddx60
|
UTSW |
8 |
62,470,234 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2174:Ddx60
|
UTSW |
8 |
62,409,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2198:Ddx60
|
UTSW |
8 |
62,411,097 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2332:Ddx60
|
UTSW |
8 |
62,490,125 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2338:Ddx60
|
UTSW |
8 |
62,465,470 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R2379:Ddx60
|
UTSW |
8 |
62,490,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4010:Ddx60
|
UTSW |
8 |
62,409,178 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4010:Ddx60
|
UTSW |
8 |
62,407,569 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R4133:Ddx60
|
UTSW |
8 |
62,425,254 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4282:Ddx60
|
UTSW |
8 |
62,447,427 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4382:Ddx60
|
UTSW |
8 |
62,402,012 (GRCm39) |
splice site |
probably null |
|
|
R4561:Ddx60
|
UTSW |
8 |
62,395,495 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4572:Ddx60
|
UTSW |
8 |
62,440,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4581:Ddx60
|
UTSW |
8 |
62,476,295 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4635:Ddx60
|
UTSW |
8 |
62,490,101 (GRCm39) |
missense |
probably benign |
0.28 |
|
R4698:Ddx60
|
UTSW |
8 |
62,465,458 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4807:Ddx60
|
UTSW |
8 |
62,432,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4858:Ddx60
|
UTSW |
8 |
62,474,348 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R4964:Ddx60
|
UTSW |
8 |
62,432,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5120:Ddx60
|
UTSW |
8 |
62,398,940 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5187:Ddx60
|
UTSW |
8 |
62,427,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5222:Ddx60
|
UTSW |
8 |
62,437,192 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5400:Ddx60
|
UTSW |
8 |
62,463,036 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R5500:Ddx60
|
UTSW |
8 |
62,403,485 (GRCm39) |
missense |
probably benign |
0.28 |
|
R5514:Ddx60
|
UTSW |
8 |
62,411,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5668:Ddx60
|
UTSW |
8 |
62,453,612 (GRCm39) |
missense |
probably benign |
0.38 |
|
R5742:Ddx60
|
UTSW |
8 |
62,401,955 (GRCm39) |
missense |
probably benign |
|
|
R5772:Ddx60
|
UTSW |
8 |
62,401,931 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5810:Ddx60
|
UTSW |
8 |
62,465,422 (GRCm39) |
nonsense |
probably null |
|
|
R5815:Ddx60
|
UTSW |
8 |
62,416,756 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5820:Ddx60
|
UTSW |
8 |
62,409,155 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R5866:Ddx60
|
UTSW |
8 |
62,393,774 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5881:Ddx60
|
UTSW |
8 |
62,490,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5977:Ddx60
|
UTSW |
8 |
62,474,444 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6048:Ddx60
|
UTSW |
8 |
62,453,616 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6061:Ddx60
|
UTSW |
8 |
62,476,275 (GRCm39) |
missense |
probably null |
0.01 |
|
R6153:Ddx60
|
UTSW |
8 |
62,398,974 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R6287:Ddx60
|
UTSW |
8 |
62,403,612 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6415:Ddx60
|
UTSW |
8 |
62,436,939 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6416:Ddx60
|
UTSW |
8 |
62,451,715 (GRCm39) |
missense |
probably benign |
|
|
R6416:Ddx60
|
UTSW |
8 |
62,430,984 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6660:Ddx60
|
UTSW |
8 |
62,409,273 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6694:Ddx60
|
UTSW |
8 |
62,490,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6715:Ddx60
|
UTSW |
8 |
62,436,924 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6720:Ddx60
|
UTSW |
8 |
62,453,723 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6937:Ddx60
|
UTSW |
8 |
62,490,103 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7153:Ddx60
|
UTSW |
8 |
62,441,142 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7274:Ddx60
|
UTSW |
8 |
62,393,142 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7409:Ddx60
|
UTSW |
8 |
62,411,612 (GRCm39) |
missense |
probably benign |
0.24 |
|
R7464:Ddx60
|
UTSW |
8 |
62,393,708 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7670:Ddx60
|
UTSW |
8 |
62,428,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7904:Ddx60
|
UTSW |
8 |
62,430,924 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7992:Ddx60
|
UTSW |
8 |
62,407,569 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8124:Ddx60
|
UTSW |
8 |
62,436,945 (GRCm39) |
missense |
probably benign |
|
|
R8125:Ddx60
|
UTSW |
8 |
62,436,945 (GRCm39) |
missense |
probably benign |
|
|
R8126:Ddx60
|
UTSW |
8 |
62,436,945 (GRCm39) |
missense |
probably benign |
|
|
R8155:Ddx60
|
UTSW |
8 |
62,470,205 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R8174:Ddx60
|
UTSW |
8 |
62,470,284 (GRCm39) |
splice site |
probably null |
|
|
R8192:Ddx60
|
UTSW |
8 |
62,431,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8271:Ddx60
|
UTSW |
8 |
62,393,142 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8301:Ddx60
|
UTSW |
8 |
62,453,631 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8304:Ddx60
|
UTSW |
8 |
62,451,803 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R8319:Ddx60
|
UTSW |
8 |
62,395,669 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8374:Ddx60
|
UTSW |
8 |
62,427,205 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8401:Ddx60
|
UTSW |
8 |
62,409,277 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R8487:Ddx60
|
UTSW |
8 |
62,427,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8804:Ddx60
|
UTSW |
8 |
62,411,640 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8826:Ddx60
|
UTSW |
8 |
62,398,990 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8829:Ddx60
|
UTSW |
8 |
62,393,695 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8881:Ddx60
|
UTSW |
8 |
62,474,343 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8884:Ddx60
|
UTSW |
8 |
62,447,553 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R8990:Ddx60
|
UTSW |
8 |
62,427,168 (GRCm39) |
nonsense |
probably null |
|
|
R9122:Ddx60
|
UTSW |
8 |
62,442,898 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9225:Ddx60
|
UTSW |
8 |
62,470,875 (GRCm39) |
missense |
probably benign |
0.36 |
|
R9278:Ddx60
|
UTSW |
8 |
62,431,012 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9293:Ddx60
|
UTSW |
8 |
62,462,994 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9405:Ddx60
|
UTSW |
8 |
62,425,248 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9766:Ddx60
|
UTSW |
8 |
62,465,312 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0003:Ddx60
|
UTSW |
8 |
62,486,451 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
X0019:Ddx60
|
UTSW |
8 |
62,416,726 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1177:Ddx60
|
UTSW |
8 |
62,453,622 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- ggacatggcaCAATGCATCCTTCAAA -3'
(R):5'- ACACCTCACCAAGGAAATGGTCTACATA -3'
Sequencing Primer
(F):5'- TGTACTTCAGAAAAGTGGTAAGGTC -3'
(R):5'- GTCTAAAGGAGACCTTTTAAACAGC -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation