Incidental Mutation 'R1733:Dock9'
| ID |
199519 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dock9
|
| Ensembl Gene |
ENSMUSG00000025558 |
| Gene Name |
dedicator of cytokinesis 9 |
| Synonyms |
D14Wsu89e, B230309H04Rik, Zizimin1 |
| MMRRC Submission |
039765-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1733 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
14 |
| Chromosomal Location |
121779458-122035249 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 121864292 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Glutamine
at position 572
(H572Q)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000040700]
[ENSMUST00000100299]
[ENSMUST00000212181]
[ENSMUST00000212376]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000040700
AA Change: H769Q
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000047881
Gene: ENSMUSG00000025558
AA Change: H769Q
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF3398
|
58 |
151 |
5.6e-36 |
PFAM |
|
PH
|
172 |
280 |
1.38e-16 |
SMART |
|
Blast:PH
|
297 |
372 |
4e-25 |
BLAST |
|
Pfam:DOCK-C2
|
631 |
822 |
5.3e-51 |
PFAM |
|
Pfam:DHR-2
|
1523 |
2068 |
2.1e-212 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000100299
AA Change: H771Q
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000097872
Gene: ENSMUSG00000025558
AA Change: H771Q
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF3398
|
58 |
153 |
1.5e-32 |
PFAM |
|
PH
|
174 |
282 |
1.38e-16 |
SMART |
|
Blast:PH
|
299 |
374 |
4e-25 |
BLAST |
|
Pfam:DOCK-C2
|
632 |
825 |
1.3e-59 |
PFAM |
|
low complexity region
|
1752 |
1763 |
N/A |
INTRINSIC |
|
Pfam:Ded_cyto
|
1836 |
2013 |
2.4e-69 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000212181
AA Change: H769Q
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000212283
AA Change: H572Q
PolyPhen 2
Score 0.009 (Sensitivity: 0.96; Specificity: 0.77)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000212376
AA Change: H783Q
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| Meta Mutation Damage Score |
0.1002 |
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.2%
- 20x: 91.9%
|
| Validation Efficiency |
95% (95/100) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamts19 |
T |
G |
18: 59,165,001 (GRCm39) |
C1034W |
probably damaging |
Het |
| Agbl2 |
G |
T |
2: 90,641,089 (GRCm39) |
K737N |
probably damaging |
Het |
| Aqp9 |
T |
A |
9: 71,019,624 (GRCm39) |
I279F |
possibly damaging |
Het |
| Aspm |
T |
A |
1: 139,384,855 (GRCm39) |
N166K |
probably benign |
Het |
| Atp13a3 |
A |
T |
16: 30,176,084 (GRCm39) |
I186N |
probably benign |
Het |
| Btaf1 |
A |
T |
19: 36,972,362 (GRCm39) |
I1366L |
probably benign |
Het |
| Camk4 |
A |
C |
18: 33,211,074 (GRCm39) |
K60Q |
possibly damaging |
Het |
| Card11 |
G |
T |
5: 140,892,388 (GRCm39) |
Q226K |
possibly damaging |
Het |
| Ccdc187 |
T |
C |
2: 26,183,670 (GRCm39) |
D110G |
possibly damaging |
Het |
| Col5a2 |
C |
T |
1: 45,446,192 (GRCm39) |
R462Q |
possibly damaging |
Het |
| Cp |
A |
T |
3: 20,022,383 (GRCm39) |
|
probably benign |
Het |
| Cpz |
A |
T |
5: 35,675,102 (GRCm39) |
V38E |
probably damaging |
Het |
| Cxcr6 |
G |
A |
9: 123,639,181 (GRCm39) |
V68I |
probably damaging |
Het |
| Cyp2a22 |
C |
A |
7: 26,634,187 (GRCm39) |
E322D |
possibly damaging |
Het |
| D130052B06Rik |
C |
T |
11: 33,573,784 (GRCm39) |
T127I |
probably benign |
Het |
| Daam2 |
T |
A |
17: 49,797,231 (GRCm39) |
M185L |
possibly damaging |
Het |
| Dnaja3 |
G |
A |
16: 4,502,029 (GRCm39) |
R11K |
probably null |
Het |
| Dnttip2 |
T |
A |
3: 122,070,397 (GRCm39) |
S537R |
probably benign |
Het |
| Dpp4 |
T |
A |
2: 62,203,213 (GRCm39) |
|
probably null |
Het |
| Enc1 |
T |
G |
13: 97,381,550 (GRCm39) |
I20S |
possibly damaging |
Het |
| Ephb6 |
T |
A |
6: 41,596,654 (GRCm39) |
H900Q |
probably benign |
Het |
| Ercc3 |
T |
C |
18: 32,400,218 (GRCm39) |
V690A |
possibly damaging |
Het |
| Fam90a1a |
C |
T |
8: 22,453,385 (GRCm39) |
Q247* |
probably null |
Het |
| Fkbp10 |
G |
A |
11: 100,314,757 (GRCm39) |
R423H |
probably benign |
Het |
| Fus |
A |
G |
7: 127,580,717 (GRCm39) |
M265V |
probably benign |
Het |
| Gas2l3 |
T |
A |
10: 89,250,127 (GRCm39) |
K330N |
probably damaging |
Het |
| Gpam |
T |
G |
19: 55,069,901 (GRCm39) |
L410F |
probably damaging |
Het |
| Gpr37l1 |
A |
T |
1: 135,089,273 (GRCm39) |
V264E |
possibly damaging |
Het |
| Grk6 |
A |
T |
13: 55,600,979 (GRCm39) |
|
probably benign |
Het |
| Gsto1 |
G |
T |
19: 47,843,674 (GRCm39) |
V19F |
probably damaging |
Het |
| H1f7 |
G |
T |
15: 98,154,016 (GRCm39) |
Q378K |
unknown |
Het |
| Hgfac |
G |
A |
5: 35,201,018 (GRCm39) |
C194Y |
probably damaging |
Het |
| Hivep1 |
A |
G |
13: 42,311,407 (GRCm39) |
N1216D |
probably damaging |
Het |
| Hrg |
C |
T |
16: 22,769,997 (GRCm39) |
A42V |
probably damaging |
Het |
| Irx4 |
A |
G |
13: 73,414,824 (GRCm39) |
D136G |
probably benign |
Het |
| Kcnn3 |
G |
T |
3: 89,559,397 (GRCm39) |
V556L |
probably benign |
Het |
| Klk1b8 |
T |
C |
7: 43,451,545 (GRCm39) |
Y179H |
possibly damaging |
Het |
| Klrb1f |
T |
A |
6: 129,031,322 (GRCm39) |
L173* |
probably null |
Het |
| Kremen2 |
A |
T |
17: 23,962,373 (GRCm39) |
|
probably null |
Het |
| Krt25 |
A |
T |
11: 99,207,378 (GRCm39) |
Y400* |
probably null |
Het |
| Lingo4 |
A |
T |
3: 94,310,485 (GRCm39) |
R474S |
probably benign |
Het |
| Lnpep |
T |
C |
17: 17,773,575 (GRCm39) |
K599E |
probably benign |
Het |
| Mapk8ip3 |
A |
T |
17: 25,155,824 (GRCm39) |
M2K |
possibly damaging |
Het |
| Mat2b |
A |
T |
11: 40,570,904 (GRCm39) |
S307T |
probably benign |
Het |
| Mcph1 |
C |
A |
8: 18,681,979 (GRCm39) |
A372D |
probably benign |
Het |
| Mfsd6 |
T |
A |
1: 52,748,524 (GRCm39) |
I114F |
probably damaging |
Het |
| Mlkl |
A |
G |
8: 112,049,380 (GRCm39) |
S248P |
probably damaging |
Het |
| Mmrn1 |
A |
T |
6: 60,954,085 (GRCm39) |
T789S |
probably benign |
Het |
| Mphosph8 |
A |
G |
14: 56,930,916 (GRCm39) |
Y735C |
probably damaging |
Het |
| Mrc1 |
T |
A |
2: 14,261,910 (GRCm39) |
Y300N |
probably damaging |
Het |
| Mrps11 |
A |
G |
7: 78,442,460 (GRCm39) |
H180R |
probably damaging |
Het |
| Msh4 |
T |
C |
3: 153,573,404 (GRCm39) |
D556G |
probably damaging |
Het |
| Myh10 |
C |
A |
11: 68,693,122 (GRCm39) |
D1472E |
probably benign |
Het |
| Myo16 |
T |
C |
8: 10,492,283 (GRCm39) |
S742P |
probably damaging |
Het |
| Nlrp5-ps |
C |
T |
7: 14,316,978 (GRCm39) |
|
noncoding transcript |
Het |
| Nrp1 |
C |
T |
8: 129,194,974 (GRCm39) |
P477S |
probably benign |
Het |
| Oplah |
G |
T |
15: 76,186,683 (GRCm39) |
C665* |
probably null |
Het |
| Or4f14b |
T |
A |
2: 111,775,625 (GRCm39) |
M59L |
probably benign |
Het |
| Or4f54 |
T |
C |
2: 111,123,210 (GRCm39) |
V199A |
probably damaging |
Het |
| Or51b17 |
T |
C |
7: 103,542,118 (GRCm39) |
S275G |
probably benign |
Het |
| Or8g22 |
G |
T |
9: 38,958,678 (GRCm39) |
H57N |
unknown |
Het |
| Otogl |
T |
C |
10: 107,619,573 (GRCm39) |
T1696A |
possibly damaging |
Het |
| Pdzrn4 |
A |
G |
15: 92,299,855 (GRCm39) |
I242V |
probably benign |
Het |
| Phgdh |
G |
A |
3: 98,235,451 (GRCm39) |
T141I |
probably benign |
Het |
| Pigv |
T |
C |
4: 133,392,237 (GRCm39) |
Y311C |
probably damaging |
Het |
| Pik3c2a |
T |
G |
7: 116,017,755 (GRCm39) |
M1L |
possibly damaging |
Het |
| Pitpnm1 |
A |
T |
19: 4,159,960 (GRCm39) |
K760* |
probably null |
Het |
| Pnrc1 |
G |
A |
4: 33,246,438 (GRCm39) |
H174Y |
probably damaging |
Het |
| Ptgis |
A |
G |
2: 167,033,888 (GRCm39) |
|
probably benign |
Het |
| Ptpn4 |
T |
C |
1: 119,643,773 (GRCm39) |
|
probably null |
Het |
| Rin3 |
T |
A |
12: 102,335,589 (GRCm39) |
L420* |
probably null |
Het |
| Sacs |
T |
G |
14: 61,442,903 (GRCm39) |
F1650V |
probably damaging |
Het |
| Sbno2 |
T |
A |
10: 79,894,342 (GRCm39) |
N1081Y |
possibly damaging |
Het |
| Sema5b |
C |
T |
16: 35,466,737 (GRCm39) |
P213L |
probably damaging |
Het |
| Sharpin |
T |
C |
15: 76,232,136 (GRCm39) |
K240R |
probably benign |
Het |
| Skint6 |
T |
A |
4: 113,034,234 (GRCm39) |
|
probably benign |
Het |
| Slc4a2 |
A |
G |
5: 24,634,565 (GRCm39) |
E68G |
probably damaging |
Het |
| Srcin1 |
C |
T |
11: 97,424,327 (GRCm39) |
V634I |
probably benign |
Het |
| Srsf10 |
T |
A |
4: 135,590,476 (GRCm39) |
F134I |
possibly damaging |
Het |
| Stab1 |
C |
A |
14: 30,867,260 (GRCm39) |
G1700V |
probably damaging |
Het |
| Sun1 |
T |
G |
5: 139,216,544 (GRCm39) |
C290W |
possibly damaging |
Het |
| Svs6 |
T |
A |
2: 164,159,577 (GRCm39) |
|
probably benign |
Het |
| Tmem8b |
G |
A |
4: 43,690,228 (GRCm39) |
|
probably null |
Het |
| Usp49 |
A |
G |
17: 47,983,238 (GRCm39) |
D81G |
probably damaging |
Het |
| Vmn1r215 |
T |
A |
13: 23,260,848 (GRCm39) |
V296D |
probably benign |
Het |
| Vmn1r6 |
T |
A |
6: 56,979,607 (GRCm39) |
S90T |
probably damaging |
Het |
| Wbp2 |
A |
G |
11: 115,974,709 (GRCm39) |
F42L |
probably benign |
Het |
| Wdr20rt |
C |
T |
12: 65,274,055 (GRCm39) |
T333I |
possibly damaging |
Het |
| Zfp341 |
C |
T |
2: 154,483,298 (GRCm39) |
A552V |
probably benign |
Het |
| Zfp607b |
A |
T |
7: 27,391,949 (GRCm39) |
H8L |
possibly damaging |
Het |
| Zfp758 |
G |
T |
17: 22,594,830 (GRCm39) |
D439Y |
probably damaging |
Het |
| Zfp946 |
T |
C |
17: 22,672,538 (GRCm39) |
Y46H |
probably damaging |
Het |
| Zic2 |
G |
A |
14: 122,716,359 (GRCm39) |
E432K |
probably damaging |
Het |
|
| Other mutations in Dock9 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00236:Dock9
|
APN |
14 |
121,905,880 (GRCm39) |
missense |
probably benign |
0.12 |
|
IGL00817:Dock9
|
APN |
14 |
121,935,703 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL00923:Dock9
|
APN |
14 |
121,844,504 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01385:Dock9
|
APN |
14 |
121,817,995 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01567:Dock9
|
APN |
14 |
121,890,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01767:Dock9
|
APN |
14 |
121,860,282 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL01811:Dock9
|
APN |
14 |
121,796,440 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02512:Dock9
|
APN |
14 |
121,856,950 (GRCm39) |
splice site |
probably benign |
|
|
IGL02525:Dock9
|
APN |
14 |
121,877,538 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02550:Dock9
|
APN |
14 |
121,935,724 (GRCm39) |
start codon destroyed |
probably null |
0.07 |
|
IGL02559:Dock9
|
APN |
14 |
121,862,559 (GRCm39) |
splice site |
probably benign |
|
|
IGL02666:Dock9
|
APN |
14 |
121,818,111 (GRCm39) |
missense |
probably benign |
0.42 |
|
IGL02674:Dock9
|
APN |
14 |
121,833,023 (GRCm39) |
splice site |
probably null |
|
|
IGL02795:Dock9
|
APN |
14 |
121,877,390 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL03074:Dock9
|
APN |
14 |
121,844,682 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03095:Dock9
|
APN |
14 |
121,876,940 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03294:Dock9
|
APN |
14 |
121,879,035 (GRCm39) |
splice site |
probably benign |
|
|
R0036:Dock9
|
UTSW |
14 |
121,860,265 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0050:Dock9
|
UTSW |
14 |
121,844,637 (GRCm39) |
missense |
probably benign |
0.43 |
|
R0050:Dock9
|
UTSW |
14 |
121,844,637 (GRCm39) |
missense |
probably benign |
0.43 |
|
R0164:Dock9
|
UTSW |
14 |
121,835,077 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0164:Dock9
|
UTSW |
14 |
121,835,077 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0270:Dock9
|
UTSW |
14 |
121,813,411 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0494:Dock9
|
UTSW |
14 |
121,899,996 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R0726:Dock9
|
UTSW |
14 |
121,889,180 (GRCm39) |
nonsense |
probably null |
|
|
R1029:Dock9
|
UTSW |
14 |
121,837,096 (GRCm39) |
splice site |
probably null |
|
|
R1214:Dock9
|
UTSW |
14 |
121,823,728 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1231:Dock9
|
UTSW |
14 |
121,813,362 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R1535:Dock9
|
UTSW |
14 |
121,783,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1629:Dock9
|
UTSW |
14 |
121,780,986 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R1637:Dock9
|
UTSW |
14 |
121,889,187 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1772:Dock9
|
UTSW |
14 |
121,847,210 (GRCm39) |
missense |
probably benign |
0.07 |
|
R1855:Dock9
|
UTSW |
14 |
121,877,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1888:Dock9
|
UTSW |
14 |
121,862,617 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1888:Dock9
|
UTSW |
14 |
121,862,617 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1901:Dock9
|
UTSW |
14 |
121,862,565 (GRCm39) |
splice site |
probably null |
|
|
R1920:Dock9
|
UTSW |
14 |
121,820,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1987:Dock9
|
UTSW |
14 |
121,829,242 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3035:Dock9
|
UTSW |
14 |
121,844,249 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R3851:Dock9
|
UTSW |
14 |
121,866,498 (GRCm39) |
splice site |
probably null |
|
|
R4020:Dock9
|
UTSW |
14 |
121,844,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4021:Dock9
|
UTSW |
14 |
121,864,324 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R4089:Dock9
|
UTSW |
14 |
121,820,883 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4258:Dock9
|
UTSW |
14 |
121,818,854 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4423:Dock9
|
UTSW |
14 |
121,799,465 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4561:Dock9
|
UTSW |
14 |
121,796,419 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4604:Dock9
|
UTSW |
14 |
121,905,871 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4646:Dock9
|
UTSW |
14 |
121,823,658 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4647:Dock9
|
UTSW |
14 |
121,823,658 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4776:Dock9
|
UTSW |
14 |
121,847,509 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4809:Dock9
|
UTSW |
14 |
121,784,008 (GRCm39) |
missense |
probably benign |
0.37 |
|
R4865:Dock9
|
UTSW |
14 |
121,780,917 (GRCm39) |
makesense |
probably null |
|
|
R4951:Dock9
|
UTSW |
14 |
121,890,547 (GRCm39) |
missense |
probably benign |
0.35 |
|
R5151:Dock9
|
UTSW |
14 |
121,815,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5359:Dock9
|
UTSW |
14 |
121,890,472 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R5366:Dock9
|
UTSW |
14 |
121,815,615 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5502:Dock9
|
UTSW |
14 |
121,847,594 (GRCm39) |
splice site |
probably null |
|
|
R5579:Dock9
|
UTSW |
14 |
121,837,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5753:Dock9
|
UTSW |
14 |
121,872,037 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5836:Dock9
|
UTSW |
14 |
121,918,763 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5858:Dock9
|
UTSW |
14 |
121,866,204 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5890:Dock9
|
UTSW |
14 |
121,905,820 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6075:Dock9
|
UTSW |
14 |
121,783,385 (GRCm39) |
missense |
probably benign |
|
|
R6298:Dock9
|
UTSW |
14 |
121,872,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6306:Dock9
|
UTSW |
14 |
121,799,492 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6321:Dock9
|
UTSW |
14 |
121,783,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6330:Dock9
|
UTSW |
14 |
121,842,655 (GRCm39) |
start codon destroyed |
probably null |
0.00 |
|
R6719:Dock9
|
UTSW |
14 |
121,847,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6784:Dock9
|
UTSW |
14 |
121,780,926 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6826:Dock9
|
UTSW |
14 |
121,860,330 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6830:Dock9
|
UTSW |
14 |
121,860,330 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6838:Dock9
|
UTSW |
14 |
121,784,008 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R6868:Dock9
|
UTSW |
14 |
121,823,676 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6919:Dock9
|
UTSW |
14 |
121,880,564 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6989:Dock9
|
UTSW |
14 |
121,864,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7539:Dock9
|
UTSW |
14 |
121,818,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7645:Dock9
|
UTSW |
14 |
121,835,075 (GRCm39) |
missense |
probably benign |
0.44 |
|
R7875:Dock9
|
UTSW |
14 |
121,863,396 (GRCm39) |
nonsense |
probably null |
|
|
R7900:Dock9
|
UTSW |
14 |
121,783,491 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R8040:Dock9
|
UTSW |
14 |
121,889,206 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8420:Dock9
|
UTSW |
14 |
121,783,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8511:Dock9
|
UTSW |
14 |
121,918,847 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8511:Dock9
|
UTSW |
14 |
121,864,801 (GRCm39) |
missense |
probably benign |
0.40 |
|
R8514:Dock9
|
UTSW |
14 |
121,896,199 (GRCm39) |
missense |
probably benign |
0.25 |
|
R8691:Dock9
|
UTSW |
14 |
121,877,517 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R8804:Dock9
|
UTSW |
14 |
121,842,595 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8894:Dock9
|
UTSW |
14 |
121,860,373 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8900:Dock9
|
UTSW |
14 |
121,817,940 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9069:Dock9
|
UTSW |
14 |
121,866,324 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9218:Dock9
|
UTSW |
14 |
121,905,871 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9233:Dock9
|
UTSW |
14 |
121,820,781 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9236:Dock9
|
UTSW |
14 |
121,876,970 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9285:Dock9
|
UTSW |
14 |
121,833,012 (GRCm39) |
missense |
probably benign |
|
|
R9451:Dock9
|
UTSW |
14 |
121,787,601 (GRCm39) |
splice site |
probably benign |
|
|
R9461:Dock9
|
UTSW |
14 |
121,842,601 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9484:Dock9
|
UTSW |
14 |
121,818,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9517:Dock9
|
UTSW |
14 |
121,829,236 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9542:Dock9
|
UTSW |
14 |
121,864,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9694:Dock9
|
UTSW |
14 |
121,818,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9701:Dock9
|
UTSW |
14 |
121,876,983 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9703:Dock9
|
UTSW |
14 |
121,781,989 (GRCm39) |
makesense |
probably null |
|
|
R9726:Dock9
|
UTSW |
14 |
121,835,149 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9741:Dock9
|
UTSW |
14 |
121,877,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Dock9
|
UTSW |
14 |
121,792,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Dock9
|
UTSW |
14 |
121,889,194 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TATCAGAAGCCGCTCCTAACTGTGC -3'
(R):5'- ACGTAACTTGCTGGTGGTCTGAC -3'
Sequencing Primer
(F):5'- CCAAGTGTCGGGACTGATAAAAATC -3'
(R):5'- TGTCAGAGGCTATCTCAAGGC -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation