Incidental Mutation 'R0090:Nup210l'
| ID |
20120 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nup210l
|
| Ensembl Gene |
ENSMUSG00000027939 |
| Gene Name |
nucleoporin 210-like |
| Synonyms |
4930548O11Rik |
| MMRRC Submission |
038377-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.432)
|
| Stock # |
R0090 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
(trace)
|
| Chromosome |
3 |
| Chromosomal Location |
90011439-90119355 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 90119086 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Isoleucine
at position 1832
(V1832I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000143368
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000029548]
[ENSMUST00000107373]
[ENSMUST00000170122]
[ENSMUST00000195998]
[ENSMUST00000196205]
[ENSMUST00000200410]
[ENSMUST00000197361]
|
| AlphaFold |
Q9D2F7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000029548
AA Change: V1832I
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000029548
Gene: ENSMUSG00000027939
AA Change: V1832I
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
13 |
32 |
N/A |
INTRINSIC |
|
BID_2
|
457 |
536 |
2.05e1 |
SMART |
|
Blast:S1
|
949 |
1023 |
2e-16 |
BLAST |
|
BID_2
|
1077 |
1152 |
4.51e-11 |
SMART |
|
Blast:BID_2
|
1468 |
1550 |
7e-15 |
BLAST |
|
transmembrane domain
|
1807 |
1829 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000107373
|
| SMART Domains |
Protein: ENSMUSP00000102996
Gene: ENSMUSG00000027935
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Miro
|
1 |
43 |
3.5e-6 |
PFAM |
|
Pfam:Arf
|
1 |
88 |
1.8e-5 |
PFAM |
|
Pfam:Ras
|
1 |
90 |
2.5e-30 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000170122
|
| SMART Domains |
Protein: ENSMUSP00000132102
Gene: ENSMUSG00000090733
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
13 |
23 |
N/A |
INTRINSIC |
|
Pfam:Ribosomal_S27e
|
28 |
82 |
9.8e-34 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195998
|
| SMART Domains |
Protein: ENSMUSP00000142942
Gene: ENSMUSG00000090733
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Ribosomal_S27e
|
1 |
50 |
3e-30 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000196196
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000196205
|
| SMART Domains |
Protein: ENSMUSP00000142536
Gene: ENSMUSG00000090733
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
21 |
N/A |
INTRINSIC |
|
Pfam:Ribosomal_S27e
|
26 |
80 |
7.5e-34 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000197028
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000200410
AA Change: V1832I
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000143368
Gene: ENSMUSG00000027939
AA Change: V1832I
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
32 |
N/A |
INTRINSIC |
|
BID_2
|
457 |
536 |
6.9e-2 |
SMART |
|
Blast:S1
|
938 |
1023 |
9e-17 |
BLAST |
|
BID_2
|
1077 |
1152 |
1.5e-13 |
SMART |
|
Blast:BID_2
|
1468 |
1550 |
7e-15 |
BLAST |
|
transmembrane domain
|
1807 |
1829 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000199428
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000198809
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000200305
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000199031
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000197361
|
| SMART Domains |
Protein: ENSMUSP00000143402
Gene: ENSMUSG00000090733
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
13 |
23 |
N/A |
INTRINSIC |
|
Pfam:Ribosomal_S27e
|
28 |
80 |
5.7e-28 |
PFAM |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 98.9%
- 3x: 98.0%
- 10x: 95.7%
- 20x: 91.4%
|
| Validation Efficiency |
99% (90/91) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a transgene insertion exhibit male infertility, asthenozoospermia, teratozoospermia, azoospermia, and seminiferous tubule degeneration. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2010315B03Rik |
T |
C |
9: 124,057,789 (GRCm39) |
|
probably benign |
Het |
| 4933427I04Rik |
A |
G |
4: 123,754,775 (GRCm39) |
T230A |
possibly damaging |
Het |
| Acsm1 |
T |
C |
7: 119,261,412 (GRCm39) |
|
probably benign |
Het |
| Acta1 |
T |
C |
8: 124,620,396 (GRCm39) |
N14S |
probably damaging |
Het |
| Aff4 |
A |
G |
11: 53,283,609 (GRCm39) |
T362A |
probably benign |
Het |
| Aggf1 |
A |
G |
13: 95,501,467 (GRCm39) |
I305T |
probably benign |
Het |
| Ap4b1 |
A |
G |
3: 103,727,745 (GRCm39) |
D325G |
possibly damaging |
Het |
| Ap4e1 |
C |
T |
2: 126,906,905 (GRCm39) |
T1055I |
possibly damaging |
Het |
| Arhgef2 |
A |
T |
3: 88,546,655 (GRCm39) |
Q496L |
probably damaging |
Het |
| Arhgef28 |
A |
G |
13: 98,211,618 (GRCm39) |
F122L |
probably damaging |
Het |
| Baiap3 |
G |
A |
17: 25,469,044 (GRCm39) |
|
probably benign |
Het |
| Casp8ap2 |
T |
A |
4: 32,640,327 (GRCm39) |
H460Q |
probably damaging |
Het |
| Casz1 |
A |
G |
4: 149,017,868 (GRCm39) |
T386A |
probably benign |
Het |
| Cd53 |
A |
T |
3: 106,674,725 (GRCm39) |
V114E |
possibly damaging |
Het |
| Celsr2 |
A |
G |
3: 108,300,643 (GRCm39) |
|
probably benign |
Het |
| Cfap300 |
T |
A |
9: 8,027,184 (GRCm39) |
N118I |
probably benign |
Het |
| Chaf1b |
G |
T |
16: 93,684,012 (GRCm39) |
A88S |
possibly damaging |
Het |
| Cldn10 |
A |
T |
14: 119,111,612 (GRCm39) |
Y194F |
probably damaging |
Het |
| Clec2e |
A |
C |
6: 129,072,181 (GRCm39) |
|
probably null |
Het |
| Cmpk2 |
A |
T |
12: 26,528,021 (GRCm39) |
T413S |
probably benign |
Het |
| Col9a1 |
T |
A |
1: 24,262,643 (GRCm39) |
|
probably null |
Het |
| Dchs1 |
G |
T |
7: 105,405,139 (GRCm39) |
Q2468K |
probably benign |
Het |
| Ddx60 |
A |
G |
8: 62,395,327 (GRCm39) |
D88G |
probably damaging |
Het |
| Dnah8 |
A |
G |
17: 31,003,064 (GRCm39) |
R3588G |
probably benign |
Het |
| Ect2 |
T |
C |
3: 27,169,625 (GRCm39) |
T774A |
probably benign |
Het |
| Ect2 |
C |
T |
3: 27,192,651 (GRCm39) |
E431K |
probably null |
Het |
| Ern1 |
A |
G |
11: 106,296,649 (GRCm39) |
V767A |
probably damaging |
Het |
| Fbln1 |
A |
C |
15: 85,108,489 (GRCm39) |
E75A |
possibly damaging |
Het |
| Fgf5 |
C |
T |
5: 98,409,846 (GRCm39) |
R132* |
probably null |
Het |
| Folh1 |
T |
C |
7: 86,375,076 (GRCm39) |
|
probably benign |
Het |
| Gdf15 |
A |
T |
8: 71,082,334 (GRCm39) |
H257Q |
probably damaging |
Het |
| Ghitm |
T |
C |
14: 36,844,176 (GRCm39) |
T322A |
probably benign |
Het |
| Gm5709 |
A |
G |
3: 59,526,192 (GRCm39) |
|
noncoding transcript |
Het |
| Hbb-y |
C |
T |
7: 103,501,950 (GRCm39) |
|
probably null |
Het |
| Hmcn2 |
A |
T |
2: 31,316,210 (GRCm39) |
D3771V |
probably damaging |
Het |
| Hspa12a |
T |
C |
19: 58,787,941 (GRCm39) |
D627G |
probably benign |
Het |
| Idh2 |
T |
C |
7: 79,747,662 (GRCm39) |
E286G |
probably damaging |
Het |
| Idh3b |
C |
A |
2: 130,122,899 (GRCm39) |
A297S |
probably benign |
Het |
| Igsf3 |
A |
G |
3: 101,342,968 (GRCm39) |
E535G |
probably damaging |
Het |
| Ilf3 |
T |
A |
9: 21,306,710 (GRCm39) |
D314E |
probably damaging |
Het |
| Itgb8 |
A |
G |
12: 119,166,298 (GRCm39) |
S78P |
probably benign |
Het |
| Itih5 |
G |
A |
2: 10,169,495 (GRCm39) |
V31I |
probably benign |
Het |
| Kcnj2 |
T |
C |
11: 110,963,853 (GRCm39) |
V415A |
probably benign |
Het |
| Kin |
A |
G |
2: 10,090,584 (GRCm39) |
Q53R |
possibly damaging |
Het |
| Krt78 |
A |
T |
15: 101,856,272 (GRCm39) |
M513K |
probably benign |
Het |
| Krtap4-8 |
A |
T |
11: 99,671,312 (GRCm39) |
|
probably benign |
Het |
| Ltbr |
T |
C |
6: 125,286,412 (GRCm39) |
|
probably benign |
Het |
| Mgat4a |
G |
A |
1: 37,529,414 (GRCm39) |
T146I |
probably damaging |
Het |
| Mrps2 |
G |
C |
2: 28,358,268 (GRCm39) |
W19C |
probably damaging |
Het |
| Mthfs |
T |
C |
9: 89,093,344 (GRCm39) |
S33P |
probably damaging |
Het |
| Myh6 |
T |
C |
14: 55,196,161 (GRCm39) |
D546G |
probably damaging |
Het |
| Nanos3 |
C |
T |
8: 84,902,763 (GRCm39) |
R133Q |
probably damaging |
Het |
| Ndst2 |
T |
C |
14: 20,777,335 (GRCm39) |
T553A |
probably damaging |
Het |
| Nlrp12 |
T |
C |
7: 3,288,664 (GRCm39) |
E616G |
probably damaging |
Het |
| Nrde2 |
T |
C |
12: 100,095,545 (GRCm39) |
|
probably benign |
Het |
| Or1e1c |
G |
A |
11: 73,266,402 (GRCm39) |
V276I |
probably benign |
Het |
| Or4k77 |
A |
T |
2: 111,199,639 (GRCm39) |
I221F |
probably damaging |
Het |
| Pcm1 |
A |
T |
8: 41,709,078 (GRCm39) |
E9D |
probably damaging |
Het |
| Pear1 |
A |
T |
3: 87,661,649 (GRCm39) |
D541E |
possibly damaging |
Het |
| Peg10 |
A |
G |
6: 4,756,063 (GRCm39) |
|
probably benign |
Het |
| Prss1 |
G |
A |
6: 41,438,166 (GRCm39) |
R31Q |
probably benign |
Het |
| Ptpn13 |
T |
C |
5: 103,717,369 (GRCm39) |
V1837A |
probably damaging |
Het |
| Rasgrp3 |
A |
G |
17: 75,805,456 (GRCm39) |
D149G |
probably damaging |
Het |
| Reg3d |
A |
T |
6: 78,355,466 (GRCm39) |
H8Q |
possibly damaging |
Het |
| Rhox4f |
A |
C |
X: 36,789,122 (GRCm39) |
V15G |
probably benign |
Het |
| Sacs |
T |
A |
14: 61,442,889 (GRCm39) |
L1645H |
probably damaging |
Het |
| Slc16a5 |
A |
T |
11: 115,355,751 (GRCm39) |
S71C |
probably damaging |
Het |
| Slc9a3 |
A |
G |
13: 74,306,847 (GRCm39) |
E324G |
probably damaging |
Het |
| Smgc |
T |
C |
15: 91,743,960 (GRCm39) |
V574A |
possibly damaging |
Het |
| Stac3 |
C |
T |
10: 127,339,799 (GRCm39) |
|
probably benign |
Het |
| Supv3l1 |
A |
G |
10: 62,265,485 (GRCm39) |
L685P |
probably benign |
Het |
| Taar2 |
G |
A |
10: 23,817,393 (GRCm39) |
R311H |
probably benign |
Het |
| Tas2r125 |
G |
T |
6: 132,887,361 (GRCm39) |
A250S |
probably benign |
Het |
| Tdrd6 |
C |
T |
17: 43,939,132 (GRCm39) |
V639I |
probably benign |
Het |
| Thap12 |
T |
G |
7: 98,365,100 (GRCm39) |
W423G |
probably damaging |
Het |
| Tmem245 |
T |
C |
4: 56,899,410 (GRCm39) |
I217V |
probably benign |
Het |
| Trip12 |
T |
A |
1: 84,709,857 (GRCm39) |
|
probably benign |
Het |
| Tshz3 |
T |
C |
7: 36,468,317 (GRCm39) |
V102A |
probably benign |
Het |
| Ubap1 |
T |
C |
4: 41,379,826 (GRCm39) |
S347P |
probably damaging |
Het |
| Usp10 |
C |
T |
8: 120,679,935 (GRCm39) |
Q612* |
probably null |
Het |
| Vmn2r72 |
T |
C |
7: 85,404,084 (GRCm39) |
I36V |
probably benign |
Het |
| Vps37a |
T |
C |
8: 40,980,030 (GRCm39) |
I63T |
possibly damaging |
Het |
| Whrn |
C |
A |
4: 63,350,969 (GRCm39) |
R9L |
possibly damaging |
Het |
| Xrcc1 |
T |
C |
7: 24,269,642 (GRCm39) |
Y401H |
probably damaging |
Het |
| Ylpm1 |
GCCTAAGCAGCAACCTAAG |
GCCTAAG |
12: 85,075,814 (GRCm39) |
|
probably benign |
Het |
| Zfhx3 |
G |
A |
8: 109,676,689 (GRCm39) |
D2580N |
possibly damaging |
Het |
| Zfhx4 |
A |
G |
3: 5,308,685 (GRCm39) |
N637S |
probably damaging |
Het |
| Zfp268 |
A |
T |
4: 145,349,195 (GRCm39) |
K211* |
probably null |
Het |
| Zyg11a |
A |
T |
4: 108,058,544 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Nup210l |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00780:Nup210l
|
APN |
3 |
90,098,156 (GRCm39) |
splice site |
probably benign |
|
|
IGL00813:Nup210l
|
APN |
3 |
90,039,725 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01375:Nup210l
|
APN |
3 |
90,067,200 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01731:Nup210l
|
APN |
3 |
90,061,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01786:Nup210l
|
APN |
3 |
90,030,083 (GRCm39) |
nonsense |
probably null |
|
|
IGL01958:Nup210l
|
APN |
3 |
90,111,231 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
IGL02094:Nup210l
|
APN |
3 |
90,087,520 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02120:Nup210l
|
APN |
3 |
90,044,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02313:Nup210l
|
APN |
3 |
90,030,099 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02336:Nup210l
|
APN |
3 |
90,088,859 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02348:Nup210l
|
APN |
3 |
90,011,471 (GRCm39) |
utr 5 prime |
probably benign |
|
|
IGL02372:Nup210l
|
APN |
3 |
90,109,278 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL02557:Nup210l
|
APN |
3 |
90,031,537 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02559:Nup210l
|
APN |
3 |
90,067,260 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02738:Nup210l
|
APN |
3 |
90,044,157 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL03231:Nup210l
|
APN |
3 |
90,096,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03257:Nup210l
|
APN |
3 |
90,087,455 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL03388:Nup210l
|
APN |
3 |
90,077,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03134:Nup210l
|
UTSW |
3 |
90,098,194 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0003:Nup210l
|
UTSW |
3 |
90,027,218 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0040:Nup210l
|
UTSW |
3 |
90,089,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0083:Nup210l
|
UTSW |
3 |
90,096,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0108:Nup210l
|
UTSW |
3 |
90,096,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0142:Nup210l
|
UTSW |
3 |
90,079,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0306:Nup210l
|
UTSW |
3 |
90,114,675 (GRCm39) |
missense |
probably benign |
0.13 |
|
R0332:Nup210l
|
UTSW |
3 |
90,039,616 (GRCm39) |
splice site |
probably benign |
|
|
R0346:Nup210l
|
UTSW |
3 |
90,096,745 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0463:Nup210l
|
UTSW |
3 |
90,087,518 (GRCm39) |
missense |
probably null |
1.00 |
|
R0622:Nup210l
|
UTSW |
3 |
90,075,047 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0765:Nup210l
|
UTSW |
3 |
90,027,184 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0990:Nup210l
|
UTSW |
3 |
90,119,232 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1014:Nup210l
|
UTSW |
3 |
90,077,355 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1036:Nup210l
|
UTSW |
3 |
90,100,247 (GRCm39) |
splice site |
probably benign |
|
|
R1177:Nup210l
|
UTSW |
3 |
90,109,310 (GRCm39) |
missense |
probably benign |
0.11 |
|
R1183:Nup210l
|
UTSW |
3 |
90,067,252 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1188:Nup210l
|
UTSW |
3 |
90,105,486 (GRCm39) |
missense |
probably benign |
0.16 |
|
R1457:Nup210l
|
UTSW |
3 |
90,098,279 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1471:Nup210l
|
UTSW |
3 |
90,077,869 (GRCm39) |
missense |
probably benign |
|
|
R1627:Nup210l
|
UTSW |
3 |
90,051,476 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1778:Nup210l
|
UTSW |
3 |
90,096,793 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1827:Nup210l
|
UTSW |
3 |
90,061,864 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1843:Nup210l
|
UTSW |
3 |
90,079,393 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1858:Nup210l
|
UTSW |
3 |
90,061,806 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1942:Nup210l
|
UTSW |
3 |
90,058,544 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2015:Nup210l
|
UTSW |
3 |
90,092,739 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2113:Nup210l
|
UTSW |
3 |
90,098,281 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R2944:Nup210l
|
UTSW |
3 |
90,088,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3736:Nup210l
|
UTSW |
3 |
90,027,320 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3740:Nup210l
|
UTSW |
3 |
90,114,701 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3741:Nup210l
|
UTSW |
3 |
90,114,701 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3742:Nup210l
|
UTSW |
3 |
90,114,701 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3771:Nup210l
|
UTSW |
3 |
90,027,201 (GRCm39) |
nonsense |
probably null |
|
|
R3773:Nup210l
|
UTSW |
3 |
90,027,201 (GRCm39) |
nonsense |
probably null |
|
|
R3879:Nup210l
|
UTSW |
3 |
90,092,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3882:Nup210l
|
UTSW |
3 |
90,031,517 (GRCm39) |
missense |
probably benign |
0.19 |
|
R3953:Nup210l
|
UTSW |
3 |
90,100,361 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3954:Nup210l
|
UTSW |
3 |
90,100,361 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3955:Nup210l
|
UTSW |
3 |
90,100,361 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3956:Nup210l
|
UTSW |
3 |
90,100,361 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4200:Nup210l
|
UTSW |
3 |
90,027,218 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4290:Nup210l
|
UTSW |
3 |
90,114,633 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4328:Nup210l
|
UTSW |
3 |
90,083,142 (GRCm39) |
splice site |
probably null |
|
|
R4629:Nup210l
|
UTSW |
3 |
90,098,181 (GRCm39) |
nonsense |
probably null |
|
|
R4629:Nup210l
|
UTSW |
3 |
90,075,182 (GRCm39) |
missense |
probably benign |
0.21 |
|
R4897:Nup210l
|
UTSW |
3 |
90,100,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4906:Nup210l
|
UTSW |
3 |
90,077,337 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4966:Nup210l
|
UTSW |
3 |
90,014,208 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5004:Nup210l
|
UTSW |
3 |
90,087,472 (GRCm39) |
nonsense |
probably null |
|
|
R5237:Nup210l
|
UTSW |
3 |
90,087,505 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5499:Nup210l
|
UTSW |
3 |
90,081,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5522:Nup210l
|
UTSW |
3 |
90,061,972 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5627:Nup210l
|
UTSW |
3 |
90,051,557 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5678:Nup210l
|
UTSW |
3 |
90,098,266 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5726:Nup210l
|
UTSW |
3 |
90,036,514 (GRCm39) |
splice site |
probably null |
|
|
R5792:Nup210l
|
UTSW |
3 |
90,107,164 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6129:Nup210l
|
UTSW |
3 |
90,011,483 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6272:Nup210l
|
UTSW |
3 |
90,077,331 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R6290:Nup210l
|
UTSW |
3 |
90,027,216 (GRCm39) |
nonsense |
probably null |
|
|
R6293:Nup210l
|
UTSW |
3 |
90,022,371 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6446:Nup210l
|
UTSW |
3 |
90,079,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6698:Nup210l
|
UTSW |
3 |
90,089,815 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R6855:Nup210l
|
UTSW |
3 |
90,044,231 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6895:Nup210l
|
UTSW |
3 |
90,067,231 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6899:Nup210l
|
UTSW |
3 |
90,075,204 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R6978:Nup210l
|
UTSW |
3 |
90,061,873 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R6980:Nup210l
|
UTSW |
3 |
90,027,234 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7038:Nup210l
|
UTSW |
3 |
90,067,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7273:Nup210l
|
UTSW |
3 |
90,025,854 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7450:Nup210l
|
UTSW |
3 |
90,022,495 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7514:Nup210l
|
UTSW |
3 |
90,117,766 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7658:Nup210l
|
UTSW |
3 |
90,119,300 (GRCm39) |
missense |
probably benign |
0.43 |
|
R7735:Nup210l
|
UTSW |
3 |
90,092,883 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7772:Nup210l
|
UTSW |
3 |
90,067,233 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7800:Nup210l
|
UTSW |
3 |
90,041,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7840:Nup210l
|
UTSW |
3 |
90,030,036 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7847:Nup210l
|
UTSW |
3 |
90,058,430 (GRCm39) |
missense |
probably benign |
|
|
R7848:Nup210l
|
UTSW |
3 |
90,111,212 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8084:Nup210l
|
UTSW |
3 |
90,043,365 (GRCm39) |
missense |
probably benign |
0.15 |
|
R8121:Nup210l
|
UTSW |
3 |
90,022,428 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8421:Nup210l
|
UTSW |
3 |
90,111,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8458:Nup210l
|
UTSW |
3 |
90,092,874 (GRCm39) |
missense |
probably null |
1.00 |
|
R8701:Nup210l
|
UTSW |
3 |
90,030,121 (GRCm39) |
missense |
probably benign |
0.41 |
|
R8720:Nup210l
|
UTSW |
3 |
90,117,681 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8770:Nup210l
|
UTSW |
3 |
90,025,850 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8896:Nup210l
|
UTSW |
3 |
90,025,932 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9033:Nup210l
|
UTSW |
3 |
90,105,396 (GRCm39) |
missense |
probably benign |
|
|
R9371:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9373:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9381:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9426:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9427:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9501:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9523:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9574:Nup210l
|
UTSW |
3 |
90,117,693 (GRCm39) |
missense |
probably benign |
|
|
R9612:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9654:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9660:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9660:Nup210l
|
UTSW |
3 |
90,105,402 (GRCm39) |
missense |
probably benign |
0.30 |
|
R9662:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9682:Nup210l
|
UTSW |
3 |
90,051,469 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R9729:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9750:Nup210l
|
UTSW |
3 |
90,117,659 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GTATCAGCATACAGGGCAGTTTAGAGG -3'
(R):5'- CCATAACCAGTGTTGTAGCCGACTC -3'
Sequencing Primer
(F):5'- aatcccagaatcccagcac -3'
(R):5'- AGGTCTTTACCTGGCTGAGT -3'
|
| Posted On |
2013-04-11 |
Incidental Mutation