|Institutional Source||Beutler Lab|
|Gene Name||collectin sub-family member 10|
|Is this an essential gene?||Probably non essential (E-score: 0.125)|
|Stock #||R0060 (G1)|
|Chromosomal Location||54410774-54466358 bp(+) (GRCm38)|
|Type of Mutation||splice site|
|DNA Base Change (assembly)||G to A at 54439146 bp|
|Amino Acid Change|
|Ref Sequence||ENSEMBL: ENSMUSP00000037867 (fasta)|
|Gene Model||predicted gene model for transcript(s): [ENSMUST00000036737]|
|Predicted Effect||probably benign
|Coding Region Coverage||
|Validation Efficiency||98% (60/61)|
|MGI Phenotype||FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. The other members of this family are secreted proteins and bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. This gene product is a cytosolic protein, a characteristic that suggests that it may have different biological functions than other C-lectins. [provided by RefSeq, Jul 2008]|
|Allele List at MGI|
|Other mutations in this stock||
|Other mutations in Colec10||
(F):5'- TGAGCAAACCATCACAACTTGTCATCT -3'
(R):5'- TCCAGGGAGAGAGTTCAACATAGAACC -3'
(F):5'- CACAACTTGTCATCTtaggtagaag -3'
(R):5'- TTGCATAAGACTCAAGTTCAGGAG -3'