Incidental Mutation 'R1812:Tanc1'
| ID |
202441 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tanc1
|
| Ensembl Gene |
ENSMUSG00000035168 |
| Gene Name |
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 |
| Synonyms |
1200003E16Rik |
| MMRRC Submission |
039840-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1812 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
59442386-59676493 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 59622023 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Methionine
at position 381
(V381M)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000123345
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000037526]
[ENSMUST00000112568]
[ENSMUST00000139863]
|
| AlphaFold |
Q0VGY8 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000037526
AA Change: V381M
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000036003
Gene: ENSMUSG00000035168
AA Change: V381M
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
22 |
N/A |
INTRINSIC |
|
low complexity region
|
60 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
171 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
229 |
240 |
N/A |
INTRINSIC |
|
low complexity region
|
439 |
451 |
N/A |
INTRINSIC |
|
low complexity region
|
455 |
475 |
N/A |
INTRINSIC |
|
ANK
|
893 |
925 |
1.06e3 |
SMART |
|
ANK
|
929 |
960 |
2.43e3 |
SMART |
|
ANK
|
964 |
993 |
1.12e-3 |
SMART |
|
Blast:ANK
|
997 |
1028 |
7e-12 |
BLAST |
|
ANK
|
1037 |
1066 |
1.78e3 |
SMART |
|
ANK
|
1075 |
1104 |
2.34e-1 |
SMART |
|
ANK
|
1108 |
1137 |
3.71e-4 |
SMART |
|
ANK
|
1141 |
1170 |
1.51e-4 |
SMART |
|
ANK
|
1174 |
1203 |
4.89e-4 |
SMART |
|
ANK
|
1207 |
1236 |
3.01e-4 |
SMART |
|
ANK
|
1240 |
1269 |
1.99e2 |
SMART |
|
TPR
|
1286 |
1319 |
7.49e1 |
SMART |
|
TPR
|
1333 |
1366 |
2.35e-1 |
SMART |
|
TPR
|
1367 |
1400 |
6.29e-2 |
SMART |
|
low complexity region
|
1416 |
1432 |
N/A |
INTRINSIC |
|
low complexity region
|
1454 |
1483 |
N/A |
INTRINSIC |
|
low complexity region
|
1656 |
1686 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000056900
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000112568
AA Change: V374M
PolyPhen 2
Score 0.896 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000108187
Gene: ENSMUSG00000035168
AA Change: V374M
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
22 |
N/A |
INTRINSIC |
|
low complexity region
|
60 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
171 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
229 |
240 |
N/A |
INTRINSIC |
|
low complexity region
|
432 |
444 |
N/A |
INTRINSIC |
|
low complexity region
|
448 |
468 |
N/A |
INTRINSIC |
|
ANK
|
886 |
918 |
1.06e3 |
SMART |
|
ANK
|
922 |
953 |
2.43e3 |
SMART |
|
ANK
|
957 |
986 |
1.12e-3 |
SMART |
|
Blast:ANK
|
990 |
1021 |
7e-12 |
BLAST |
|
ANK
|
1030 |
1059 |
1.78e3 |
SMART |
|
ANK
|
1068 |
1097 |
2.34e-1 |
SMART |
|
ANK
|
1101 |
1130 |
3.71e-4 |
SMART |
|
ANK
|
1134 |
1163 |
1.51e-4 |
SMART |
|
ANK
|
1167 |
1196 |
4.89e-4 |
SMART |
|
ANK
|
1200 |
1229 |
3.01e-4 |
SMART |
|
ANK
|
1233 |
1262 |
1.99e2 |
SMART |
|
TPR
|
1279 |
1312 |
7.49e1 |
SMART |
|
TPR
|
1326 |
1359 |
2.35e-1 |
SMART |
|
TPR
|
1360 |
1393 |
6.29e-2 |
SMART |
|
low complexity region
|
1409 |
1425 |
N/A |
INTRINSIC |
|
low complexity region
|
1447 |
1476 |
N/A |
INTRINSIC |
|
low complexity region
|
1649 |
1679 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000139863
AA Change: V381M
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000123345
Gene: ENSMUSG00000035168
AA Change: V381M
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
22 |
N/A |
INTRINSIC |
|
low complexity region
|
60 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
171 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
229 |
240 |
N/A |
INTRINSIC |
|
low complexity region
|
439 |
451 |
N/A |
INTRINSIC |
|
low complexity region
|
455 |
475 |
N/A |
INTRINSIC |
|
ANK
|
893 |
925 |
1.06e3 |
SMART |
|
ANK
|
929 |
960 |
2.43e3 |
SMART |
|
ANK
|
964 |
993 |
1.12e-3 |
SMART |
|
Blast:ANK
|
997 |
1028 |
7e-12 |
BLAST |
|
ANK
|
1037 |
1066 |
1.78e3 |
SMART |
|
ANK
|
1075 |
1104 |
2.34e-1 |
SMART |
|
ANK
|
1108 |
1137 |
3.71e-4 |
SMART |
|
ANK
|
1141 |
1170 |
1.51e-4 |
SMART |
|
ANK
|
1174 |
1203 |
4.89e-4 |
SMART |
|
ANK
|
1207 |
1236 |
3.01e-4 |
SMART |
|
ANK
|
1240 |
1269 |
1.99e2 |
SMART |
|
TPR
|
1286 |
1319 |
7.49e1 |
SMART |
|
TPR
|
1333 |
1366 |
2.35e-1 |
SMART |
|
TPR
|
1367 |
1400 |
6.29e-2 |
SMART |
|
low complexity region
|
1416 |
1432 |
N/A |
INTRINSIC |
|
low complexity region
|
1454 |
1483 |
N/A |
INTRINSIC |
|
low complexity region
|
1656 |
1686 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 97.3%
- 3x: 96.3%
- 10x: 93.2%
- 20x: 85.7%
|
| Validation Efficiency |
100% (1/1) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a gene trap vector exhibit decreased spine density in the CA3 region and impaired spatial memory. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 72 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700017B05Rik |
G |
A |
9: 57,164,740 (GRCm39) |
Q545* |
probably null |
Het |
| Aadacl2 |
T |
C |
3: 59,932,498 (GRCm39) |
C338R |
probably damaging |
Het |
| Abcb4 |
G |
A |
5: 8,978,578 (GRCm39) |
|
probably null |
Het |
| Adam17 |
T |
C |
12: 21,411,768 (GRCm39) |
D41G |
probably damaging |
Het |
| Angptl7 |
T |
A |
4: 148,582,540 (GRCm39) |
I119F |
probably damaging |
Het |
| Arid1b |
T |
A |
17: 5,387,304 (GRCm39) |
S1586T |
probably benign |
Het |
| Arid4b |
C |
T |
13: 14,370,014 (GRCm39) |
A1170V |
probably damaging |
Het |
| Atad5 |
A |
G |
11: 80,023,873 (GRCm39) |
T1659A |
probably damaging |
Het |
| Bub1b |
T |
G |
2: 118,462,902 (GRCm39) |
D754E |
probably benign |
Het |
| Cdkn1a |
T |
C |
17: 29,317,539 (GRCm39) |
V53A |
probably benign |
Het |
| Chsy1 |
T |
G |
7: 65,821,565 (GRCm39) |
V600G |
probably benign |
Het |
| Cntrl |
G |
A |
2: 35,039,481 (GRCm39) |
V561M |
probably damaging |
Het |
| Col6a5 |
A |
G |
9: 105,805,253 (GRCm39) |
C1218R |
unknown |
Het |
| Crhr1 |
T |
C |
11: 104,059,973 (GRCm39) |
L140P |
probably damaging |
Het |
| Cyb5b |
CAGAG |
CAG |
8: 107,897,020 (GRCm39) |
|
probably null |
Het |
| Cyp3a59 |
A |
T |
5: 146,039,621 (GRCm39) |
Q298L |
probably damaging |
Het |
| Dctn1 |
A |
G |
6: 83,169,500 (GRCm39) |
E638G |
possibly damaging |
Het |
| Ddx41 |
A |
G |
13: 55,683,767 (GRCm39) |
I88T |
probably benign |
Het |
| Dennd11 |
A |
G |
6: 40,386,365 (GRCm39) |
I288T |
probably benign |
Het |
| Diaph1 |
G |
T |
18: 38,024,071 (GRCm39) |
P589Q |
unknown |
Het |
| Dip2b |
C |
A |
15: 100,096,819 (GRCm39) |
|
probably null |
Het |
| Dscaml1 |
G |
A |
9: 45,662,584 (GRCm39) |
|
probably null |
Het |
| Dync1h1 |
C |
T |
12: 110,629,334 (GRCm39) |
A4246V |
possibly damaging |
Het |
| Epb41l1 |
T |
C |
2: 156,338,431 (GRCm39) |
I158T |
probably damaging |
Het |
| Fat1 |
A |
G |
8: 45,489,840 (GRCm39) |
Y3584C |
probably damaging |
Het |
| Fxyd5 |
T |
A |
7: 30,737,355 (GRCm39) |
|
probably null |
Het |
| Gapvd1 |
T |
A |
2: 34,615,076 (GRCm39) |
K336* |
probably null |
Het |
| Gm9637 |
G |
A |
14: 19,402,395 (GRCm38) |
|
noncoding transcript |
Het |
| Gpr65 |
C |
T |
12: 98,242,001 (GRCm39) |
T218M |
probably damaging |
Het |
| Gsdma3 |
T |
C |
11: 98,523,219 (GRCm39) |
V203A |
probably damaging |
Het |
| Helb |
T |
A |
10: 119,925,471 (GRCm39) |
K969* |
probably null |
Het |
| Hipk2 |
G |
A |
6: 38,675,098 (GRCm39) |
A1188V |
probably benign |
Het |
| Itpk1 |
T |
A |
12: 102,540,317 (GRCm39) |
E255D |
probably benign |
Het |
| Kif21a |
T |
C |
15: 90,855,969 (GRCm39) |
D596G |
possibly damaging |
Het |
| Kif5a |
A |
T |
10: 127,077,879 (GRCm39) |
I405N |
probably benign |
Het |
| Klk1b11 |
T |
A |
7: 43,427,179 (GRCm39) |
|
probably null |
Het |
| Luzp1 |
T |
A |
4: 136,269,642 (GRCm39) |
L622M |
probably benign |
Het |
| Macf1 |
T |
A |
4: 123,325,817 (GRCm39) |
I5227F |
probably damaging |
Het |
| Mapk10 |
A |
C |
5: 103,061,128 (GRCm39) |
S470A |
probably damaging |
Het |
| Morc2a |
C |
T |
11: 3,635,831 (GRCm39) |
T897I |
probably damaging |
Het |
| Nmbr |
A |
G |
10: 14,636,283 (GRCm39) |
|
probably null |
Het |
| Nosip |
T |
A |
7: 44,725,998 (GRCm39) |
M214K |
probably damaging |
Het |
| Or13c7d |
G |
T |
4: 43,770,230 (GRCm39) |
Y260* |
probably null |
Het |
| Or52m2 |
A |
T |
7: 102,263,577 (GRCm39) |
N206K |
possibly damaging |
Het |
| Or52r1 |
T |
C |
7: 102,537,285 (GRCm39) |
Y25C |
probably benign |
Het |
| Or5w13 |
A |
G |
2: 87,523,447 (GRCm39) |
F260L |
probably benign |
Het |
| Pik3c2a |
A |
T |
7: 116,016,899 (GRCm39) |
V286E |
probably damaging |
Het |
| Ppfia4 |
T |
A |
1: 134,252,311 (GRCm39) |
I388F |
probably benign |
Het |
| Ppm1f |
A |
G |
16: 16,735,651 (GRCm39) |
H289R |
probably damaging |
Het |
| Ptprz1 |
T |
A |
6: 22,959,711 (GRCm39) |
D69E |
probably benign |
Het |
| Rad54b |
A |
T |
4: 11,612,770 (GRCm39) |
T801S |
probably damaging |
Het |
| Ramp1 |
A |
T |
1: 91,124,579 (GRCm39) |
N47Y |
probably damaging |
Het |
| Rnf32 |
T |
A |
5: 29,411,258 (GRCm39) |
H181Q |
possibly damaging |
Het |
| Rpa2 |
T |
C |
4: 132,495,996 (GRCm39) |
F6L |
probably benign |
Het |
| Ryr2 |
C |
A |
13: 11,575,472 (GRCm39) |
R4842L |
probably damaging |
Het |
| Scn11a |
G |
T |
9: 119,609,931 (GRCm39) |
C972* |
probably null |
Het |
| Setd2 |
C |
T |
9: 110,379,170 (GRCm39) |
T995I |
probably damaging |
Het |
| Slc39a7 |
A |
G |
17: 34,247,789 (GRCm39) |
L471P |
probably damaging |
Het |
| Slc6a21 |
C |
G |
7: 44,932,371 (GRCm39) |
S350R |
probably damaging |
Het |
| Slx4ip |
A |
G |
2: 136,910,115 (GRCm39) |
N300S |
probably benign |
Het |
| Spef2 |
G |
A |
15: 9,679,435 (GRCm39) |
P634L |
probably damaging |
Het |
| Stk32b |
G |
A |
5: 37,624,102 (GRCm39) |
A215V |
probably damaging |
Het |
| Svil |
A |
T |
18: 5,097,545 (GRCm39) |
Y1676F |
probably damaging |
Het |
| Tanc2 |
T |
C |
11: 105,777,212 (GRCm39) |
F797L |
probably benign |
Het |
| Tas2r120 |
T |
G |
6: 132,634,564 (GRCm39) |
C215W |
probably benign |
Het |
| Tenm4 |
G |
A |
7: 96,545,147 (GRCm39) |
D2388N |
probably damaging |
Het |
| Thsd4 |
C |
T |
9: 59,964,220 (GRCm39) |
S64N |
probably damaging |
Het |
| Thsd7b |
C |
T |
1: 129,686,347 (GRCm39) |
R630C |
probably damaging |
Het |
| Top3a |
A |
G |
11: 60,650,188 (GRCm39) |
I145T |
probably damaging |
Het |
| Vmn2r78 |
A |
G |
7: 86,569,995 (GRCm39) |
D171G |
probably benign |
Het |
| Vmn2r82 |
A |
G |
10: 79,215,046 (GRCm39) |
E343G |
probably benign |
Het |
| Wdr70 |
T |
C |
15: 8,108,663 (GRCm39) |
D161G |
probably benign |
Het |
|
| Other mutations in Tanc1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00340:Tanc1
|
APN |
2 |
59,621,185 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL00484:Tanc1
|
APN |
2 |
59,623,520 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00688:Tanc1
|
APN |
2 |
59,645,735 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00765:Tanc1
|
APN |
2 |
59,636,645 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL01576:Tanc1
|
APN |
2 |
59,628,079 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01590:Tanc1
|
APN |
2 |
59,615,817 (GRCm39) |
missense |
probably benign |
|
|
IGL02016:Tanc1
|
APN |
2 |
59,673,934 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02373:Tanc1
|
APN |
2 |
59,626,372 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02539:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02540:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02541:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02543:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02559:Tanc1
|
APN |
2 |
59,554,998 (GRCm39) |
splice site |
probably benign |
|
|
IGL02626:Tanc1
|
APN |
2 |
59,630,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02669:Tanc1
|
APN |
2 |
59,630,330 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02902:Tanc1
|
APN |
2 |
59,623,431 (GRCm39) |
splice site |
probably benign |
|
|
Oreja
|
UTSW |
2 |
59,622,148 (GRCm39) |
synonymous |
silent |
|
|
R0178:Tanc1
|
UTSW |
2 |
59,665,791 (GRCm39) |
nonsense |
probably null |
|
|
R0347:Tanc1
|
UTSW |
2 |
59,673,335 (GRCm39) |
missense |
probably benign |
|
|
R0570:Tanc1
|
UTSW |
2 |
59,626,382 (GRCm39) |
splice site |
probably benign |
|
|
R0660:Tanc1
|
UTSW |
2 |
59,674,228 (GRCm39) |
nonsense |
probably null |
|
|
R0664:Tanc1
|
UTSW |
2 |
59,674,228 (GRCm39) |
nonsense |
probably null |
|
|
R0898:Tanc1
|
UTSW |
2 |
59,621,132 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1333:Tanc1
|
UTSW |
2 |
59,673,835 (GRCm39) |
missense |
probably benign |
|
|
R1575:Tanc1
|
UTSW |
2 |
59,621,995 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1608:Tanc1
|
UTSW |
2 |
59,628,038 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R1616:Tanc1
|
UTSW |
2 |
59,615,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1703:Tanc1
|
UTSW |
2 |
59,673,365 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1727:Tanc1
|
UTSW |
2 |
59,621,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1809:Tanc1
|
UTSW |
2 |
59,630,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1925:Tanc1
|
UTSW |
2 |
59,555,095 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R1951:Tanc1
|
UTSW |
2 |
59,622,156 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2174:Tanc1
|
UTSW |
2 |
59,674,177 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2228:Tanc1
|
UTSW |
2 |
59,555,068 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2267:Tanc1
|
UTSW |
2 |
59,667,563 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4191:Tanc1
|
UTSW |
2 |
59,669,357 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4476:Tanc1
|
UTSW |
2 |
59,672,340 (GRCm39) |
splice site |
probably null |
|
|
R4632:Tanc1
|
UTSW |
2 |
59,626,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4825:Tanc1
|
UTSW |
2 |
59,529,766 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4982:Tanc1
|
UTSW |
2 |
59,630,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5338:Tanc1
|
UTSW |
2 |
59,626,178 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5657:Tanc1
|
UTSW |
2 |
59,665,051 (GRCm39) |
splice site |
probably null |
|
|
R5672:Tanc1
|
UTSW |
2 |
59,602,697 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5703:Tanc1
|
UTSW |
2 |
59,626,341 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5707:Tanc1
|
UTSW |
2 |
59,588,874 (GRCm39) |
missense |
probably benign |
|
|
R5778:Tanc1
|
UTSW |
2 |
59,529,691 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5795:Tanc1
|
UTSW |
2 |
59,637,926 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R5831:Tanc1
|
UTSW |
2 |
59,615,685 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5849:Tanc1
|
UTSW |
2 |
59,630,248 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5912:Tanc1
|
UTSW |
2 |
59,622,030 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5944:Tanc1
|
UTSW |
2 |
59,667,564 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6057:Tanc1
|
UTSW |
2 |
59,647,837 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6142:Tanc1
|
UTSW |
2 |
59,663,566 (GRCm39) |
nonsense |
probably null |
|
|
R6179:Tanc1
|
UTSW |
2 |
59,673,320 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6185:Tanc1
|
UTSW |
2 |
59,621,929 (GRCm39) |
splice site |
probably null |
|
|
R6192:Tanc1
|
UTSW |
2 |
59,669,305 (GRCm39) |
splice site |
probably null |
|
|
R6196:Tanc1
|
UTSW |
2 |
59,674,366 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6197:Tanc1
|
UTSW |
2 |
59,674,366 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6230:Tanc1
|
UTSW |
2 |
59,672,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6275:Tanc1
|
UTSW |
2 |
59,673,854 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6415:Tanc1
|
UTSW |
2 |
59,667,458 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6480:Tanc1
|
UTSW |
2 |
59,637,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6578:Tanc1
|
UTSW |
2 |
59,626,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6786:Tanc1
|
UTSW |
2 |
59,622,150 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7006:Tanc1
|
UTSW |
2 |
59,626,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7133:Tanc1
|
UTSW |
2 |
59,627,953 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7381:Tanc1
|
UTSW |
2 |
59,615,670 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7422:Tanc1
|
UTSW |
2 |
59,636,688 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8392:Tanc1
|
UTSW |
2 |
59,636,651 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8692:Tanc1
|
UTSW |
2 |
59,673,989 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8730:Tanc1
|
UTSW |
2 |
59,601,590 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8731:Tanc1
|
UTSW |
2 |
59,673,596 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8813:Tanc1
|
UTSW |
2 |
59,630,265 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8815:Tanc1
|
UTSW |
2 |
59,621,185 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R8933:Tanc1
|
UTSW |
2 |
59,615,800 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9015:Tanc1
|
UTSW |
2 |
59,622,224 (GRCm39) |
missense |
probably benign |
|
|
R9042:Tanc1
|
UTSW |
2 |
59,673,766 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9154:Tanc1
|
UTSW |
2 |
59,630,132 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9269:Tanc1
|
UTSW |
2 |
59,630,432 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9283:Tanc1
|
UTSW |
2 |
59,630,174 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9380:Tanc1
|
UTSW |
2 |
59,665,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9422:Tanc1
|
UTSW |
2 |
59,637,933 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9428:Tanc1
|
UTSW |
2 |
59,601,548 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9694:Tanc1
|
UTSW |
2 |
59,626,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF028:Tanc1
|
UTSW |
2 |
59,673,613 (GRCm39) |
small deletion |
probably benign |
|
|
RF049:Tanc1
|
UTSW |
2 |
59,673,613 (GRCm39) |
small deletion |
probably benign |
|
|
X0063:Tanc1
|
UTSW |
2 |
59,674,324 (GRCm39) |
nonsense |
probably null |
|
|
X0064:Tanc1
|
UTSW |
2 |
59,674,456 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Tanc1
|
UTSW |
2 |
59,602,873 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
Z1177:Tanc1
|
UTSW |
2 |
59,622,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Tanc1
|
UTSW |
2 |
59,621,231 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GGACTGGGAGTTACTGTAACAG -3'
(R):5'- GATCTGTCTCATGCGGCTTC -3'
Sequencing Primer
(F):5'- CTGGGAGTTACTGTAACAGGATACC -3'
(R):5'- TTCCGTGACAGCTCAGTGC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation