Incidental Mutation 'R1799:Ralgapa2'
| ID |
202900 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ralgapa2
|
| Ensembl Gene |
ENSMUSG00000037110 |
| Gene Name |
Ral GTPase activating protein, alpha subunit 2 (catalytic) |
| Synonyms |
AS250, A230067G21Rik, RGC2 |
| MMRRC Submission |
039829-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.209)
|
| Stock # |
R1799 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
146081799-146354264 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 146184648 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 1453
(E1453G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000153734
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000109986]
[ENSMUST00000131824]
[ENSMUST00000228797]
|
| AlphaFold |
A3KGS3 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000109986
AA Change: E1406G
PolyPhen 2
Score 0.008 (Sensitivity: 0.96; Specificity: 0.76)
|
| SMART Domains |
Protein: ENSMUSP00000105613
Gene: ENSMUSG00000037110
AA Change: E1406G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
469 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
1017 |
1028 |
N/A |
INTRINSIC |
|
low complexity region
|
1296 |
1301 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
1701 |
1877 |
6.8e-48 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131824
AA Change: E1368G
PolyPhen 2
Score 0.008 (Sensitivity: 0.96; Specificity: 0.76)
|
| SMART Domains |
Protein: ENSMUSP00000122039
Gene: ENSMUSG00000037110
AA Change: E1368G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
469 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
979 |
990 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1263 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
1663 |
1842 |
1.3e-66 |
PFAM |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000146307
AA Change: E394G
|
| SMART Domains |
Protein: ENSMUSP00000114547
Gene: ENSMUSG00000037110
AA Change: E394G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
17 |
N/A |
INTRINSIC |
|
low complexity region
|
285 |
290 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
690 |
830 |
4.9e-39 |
PFAM |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000149499
AA Change: E1038G
|
| SMART Domains |
Protein: ENSMUSP00000122017
Gene: ENSMUSG00000037110
AA Change: E1038G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
140 |
151 |
N/A |
INTRINSIC |
|
low complexity region
|
650 |
661 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
934 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
1334 |
1511 |
2.4e-48 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000228797
AA Change: E1453G
PolyPhen 2
Score 0.023 (Sensitivity: 0.95; Specificity: 0.81)
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.3%
- 20x: 92.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased incidence and severity of induced urothelial bladder tumors. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 102 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A930011G23Rik |
A |
G |
5: 99,382,435 (GRCm39) |
L271P |
probably benign |
Het |
| Adamts3 |
A |
C |
5: 89,923,280 (GRCm39) |
D175E |
probably benign |
Het |
| Adcy4 |
T |
C |
14: 56,008,929 (GRCm39) |
T833A |
probably benign |
Het |
| Adgrf5 |
A |
T |
17: 43,750,958 (GRCm39) |
I508F |
probably damaging |
Het |
| Arhgap9 |
G |
T |
10: 127,163,593 (GRCm39) |
V464L |
probably damaging |
Het |
| Atp10a |
T |
A |
7: 58,474,182 (GRCm39) |
D1156E |
probably damaging |
Het |
| Atp2a1 |
A |
T |
7: 126,049,314 (GRCm39) |
M576K |
probably benign |
Het |
| Atrx |
T |
C |
X: 104,891,235 (GRCm39) |
Q1536R |
probably damaging |
Het |
| Ccdc141 |
A |
C |
2: 76,842,015 (GRCm39) |
V1472G |
possibly damaging |
Het |
| Cd84 |
A |
G |
1: 171,700,317 (GRCm39) |
T145A |
possibly damaging |
Het |
| Celsr1 |
G |
T |
15: 85,916,886 (GRCm39) |
N362K |
probably damaging |
Het |
| Cep290 |
G |
A |
10: 100,352,058 (GRCm39) |
A755T |
probably benign |
Het |
| Cfap70 |
T |
A |
14: 20,445,067 (GRCm39) |
E1071V |
probably damaging |
Het |
| Cps1 |
T |
C |
1: 67,248,801 (GRCm39) |
V1176A |
probably damaging |
Het |
| Csf2rb2 |
A |
C |
15: 78,181,268 (GRCm39) |
N41K |
probably damaging |
Het |
| Csn1s2a |
G |
A |
5: 87,926,052 (GRCm39) |
V43M |
probably damaging |
Het |
| Cyp26b1 |
T |
C |
6: 84,561,254 (GRCm39) |
D136G |
probably benign |
Het |
| Cyp7b1 |
A |
G |
3: 18,151,616 (GRCm39) |
L199P |
probably benign |
Het |
| Dapk1 |
C |
T |
13: 60,867,468 (GRCm39) |
T225I |
probably damaging |
Het |
| Dio2 |
T |
A |
12: 90,696,680 (GRCm39) |
T103S |
probably benign |
Het |
| Dipk1a |
C |
A |
5: 108,057,713 (GRCm39) |
V237F |
probably damaging |
Het |
| Dnhd1 |
T |
A |
7: 105,304,974 (GRCm39) |
S339T |
probably benign |
Het |
| Drc1 |
A |
G |
5: 30,523,841 (GRCm39) |
N737D |
probably damaging |
Het |
| Efhc1 |
C |
T |
1: 21,049,762 (GRCm39) |
P541S |
probably benign |
Het |
| Elmo2 |
A |
T |
2: 165,134,077 (GRCm39) |
I637N |
probably damaging |
Het |
| Eps15 |
T |
A |
4: 109,240,034 (GRCm39) |
D492E |
probably damaging |
Het |
| Ermn |
G |
T |
2: 57,938,249 (GRCm39) |
N121K |
probably benign |
Het |
| F5 |
A |
G |
1: 164,021,100 (GRCm39) |
T1192A |
possibly damaging |
Het |
| Fbxo22 |
T |
C |
9: 55,130,771 (GRCm39) |
F347L |
probably benign |
Het |
| Fbxw15 |
G |
A |
9: 109,387,314 (GRCm39) |
S227F |
probably damaging |
Het |
| Foxj3 |
A |
G |
4: 119,476,548 (GRCm39) |
N242S |
probably benign |
Het |
| Gjb3 |
G |
A |
4: 127,220,224 (GRCm39) |
R103W |
probably damaging |
Het |
| Grm4 |
A |
G |
17: 27,691,914 (GRCm39) |
V235A |
probably damaging |
Het |
| Gstm4 |
T |
C |
3: 107,950,874 (GRCm39) |
N74S |
probably damaging |
Het |
| Gtf3c3 |
A |
G |
1: 54,459,583 (GRCm39) |
V393A |
possibly damaging |
Het |
| Hltf |
T |
A |
3: 20,159,855 (GRCm39) |
L702H |
probably damaging |
Het |
| Inpp4a |
T |
A |
1: 37,432,059 (GRCm39) |
V153E |
possibly damaging |
Het |
| Kmt5c |
T |
C |
7: 4,745,729 (GRCm39) |
|
probably null |
Het |
| Kynu |
A |
G |
2: 43,494,169 (GRCm39) |
R201G |
possibly damaging |
Het |
| Lrp2 |
T |
A |
2: 69,333,874 (GRCm39) |
T1456S |
probably benign |
Het |
| Lrrc40 |
G |
A |
3: 157,742,441 (GRCm39) |
V19I |
probably benign |
Het |
| M1ap |
T |
A |
6: 82,982,491 (GRCm39) |
C258* |
probably null |
Het |
| Man2a1 |
T |
C |
17: 65,059,452 (GRCm39) |
L1113P |
probably benign |
Het |
| Man2a1 |
C |
T |
17: 64,976,492 (GRCm39) |
R427W |
probably damaging |
Het |
| Meikin |
C |
A |
11: 54,308,613 (GRCm39) |
Q404K |
probably benign |
Het |
| Mfsd4a |
T |
C |
1: 131,981,334 (GRCm39) |
I222V |
possibly damaging |
Het |
| N4bp2 |
A |
G |
5: 65,964,168 (GRCm39) |
N739S |
possibly damaging |
Het |
| Ncoa2 |
A |
T |
1: 13,232,517 (GRCm39) |
|
probably null |
Het |
| Nisch |
G |
T |
14: 30,899,228 (GRCm39) |
|
probably benign |
Het |
| Nmur2 |
A |
G |
11: 55,920,447 (GRCm39) |
V266A |
probably damaging |
Het |
| Npcd |
G |
A |
15: 79,712,987 (GRCm39) |
R147C |
probably damaging |
Het |
| Or4q3 |
T |
A |
14: 50,583,537 (GRCm39) |
M121L |
probably benign |
Het |
| Or5ac25 |
T |
A |
16: 59,182,243 (GRCm39) |
I113F |
probably benign |
Het |
| Pals2 |
T |
A |
6: 50,173,525 (GRCm39) |
M463K |
probably damaging |
Het |
| Parp4 |
A |
T |
14: 56,885,589 (GRCm39) |
H1556L |
unknown |
Het |
| Pcdh9 |
G |
T |
14: 94,126,107 (GRCm39) |
A21E |
probably benign |
Het |
| Phtf1 |
A |
G |
3: 103,903,958 (GRCm39) |
E436G |
probably benign |
Het |
| Piezo2 |
C |
A |
18: 63,165,911 (GRCm39) |
|
probably null |
Het |
| Piezo2 |
T |
C |
18: 63,241,158 (GRCm39) |
Y690C |
probably damaging |
Het |
| Pla2g4f |
T |
C |
2: 120,141,549 (GRCm39) |
R183G |
possibly damaging |
Het |
| Plxnd1 |
T |
C |
6: 115,971,018 (GRCm39) |
D250G |
probably damaging |
Het |
| Ppig |
A |
G |
2: 69,579,744 (GRCm39) |
D426G |
unknown |
Het |
| Ppp3cb |
T |
C |
14: 20,574,540 (GRCm39) |
E185G |
possibly damaging |
Het |
| Qsox1 |
A |
T |
1: 155,670,364 (GRCm39) |
M151K |
probably null |
Het |
| Rnf167 |
G |
A |
11: 70,540,838 (GRCm39) |
V191I |
probably benign |
Het |
| Rp1 |
T |
C |
1: 4,419,055 (GRCm39) |
K686E |
possibly damaging |
Het |
| Ryr1 |
T |
G |
7: 28,767,046 (GRCm39) |
Q2979P |
probably damaging |
Het |
| Scaf1 |
T |
A |
7: 44,657,443 (GRCm39) |
I479F |
probably damaging |
Het |
| Septin8 |
A |
G |
11: 53,425,310 (GRCm39) |
T68A |
probably benign |
Het |
| Sh3rf1 |
A |
T |
8: 61,825,661 (GRCm39) |
N552I |
probably damaging |
Het |
| Shoc1 |
A |
T |
4: 59,099,383 (GRCm39) |
V103D |
possibly damaging |
Het |
| Slc1a3 |
A |
G |
15: 8,717,888 (GRCm39) |
L68P |
probably damaging |
Het |
| Slc39a6 |
G |
A |
18: 24,718,524 (GRCm39) |
P511L |
probably benign |
Het |
| Slc9c1 |
A |
G |
16: 45,374,652 (GRCm39) |
Y339C |
probably damaging |
Het |
| Smarcal1 |
G |
T |
1: 72,625,120 (GRCm39) |
C89F |
probably damaging |
Het |
| Smu1 |
A |
T |
4: 40,745,537 (GRCm39) |
M261K |
probably damaging |
Het |
| Spag8 |
T |
G |
4: 43,653,087 (GRCm39) |
|
probably benign |
Het |
| Spag8 |
T |
C |
4: 43,653,345 (GRCm39) |
|
probably benign |
Het |
| Spata31d1a |
T |
C |
13: 59,851,216 (GRCm39) |
D304G |
probably benign |
Het |
| Spdl1 |
A |
T |
11: 34,711,856 (GRCm39) |
L298* |
probably null |
Het |
| Stac2 |
C |
T |
11: 97,930,444 (GRCm39) |
|
probably null |
Het |
| Stag1 |
A |
G |
9: 100,835,515 (GRCm39) |
|
probably null |
Het |
| Stpg2 |
C |
T |
3: 139,125,542 (GRCm39) |
P445L |
probably damaging |
Het |
| Sult2a8 |
A |
T |
7: 14,157,451 (GRCm39) |
V128E |
probably damaging |
Het |
| Synm |
A |
G |
7: 67,385,707 (GRCm39) |
F210L |
probably damaging |
Het |
| Tbck |
C |
G |
3: 132,480,263 (GRCm39) |
A714G |
probably benign |
Het |
| Tcerg1 |
A |
T |
18: 42,694,012 (GRCm39) |
Y711F |
possibly damaging |
Het |
| Tnfrsf25 |
A |
G |
4: 152,201,465 (GRCm39) |
T98A |
probably benign |
Het |
| Togaram2 |
T |
C |
17: 71,998,450 (GRCm39) |
S218P |
probably damaging |
Het |
| Tpp1 |
A |
T |
7: 105,399,515 (GRCm39) |
D84E |
probably benign |
Het |
| Trim30d |
G |
T |
7: 104,132,682 (GRCm39) |
Q202K |
probably damaging |
Het |
| Trim37 |
T |
A |
11: 87,068,845 (GRCm39) |
V397E |
probably damaging |
Het |
| Triml1 |
A |
T |
8: 43,583,512 (GRCm39) |
I363N |
probably damaging |
Het |
| Trpm6 |
T |
A |
19: 18,869,363 (GRCm39) |
|
probably null |
Het |
| Tsc2 |
T |
C |
17: 24,823,382 (GRCm39) |
S1055G |
probably benign |
Het |
| Ubr5 |
T |
C |
15: 37,989,621 (GRCm39) |
D2065G |
probably damaging |
Het |
| Uggt2 |
G |
T |
14: 119,269,688 (GRCm39) |
P948Q |
probably benign |
Het |
| Vps13c |
A |
T |
9: 67,851,399 (GRCm39) |
S2345C |
probably damaging |
Het |
| Wtap |
G |
T |
17: 13,199,771 (GRCm39) |
R48S |
possibly damaging |
Het |
| Zbtb38 |
A |
G |
9: 96,570,934 (GRCm39) |
V50A |
probably damaging |
Het |
| Zcchc2 |
T |
A |
1: 105,958,017 (GRCm39) |
S829R |
probably benign |
Het |
| Zfp385b |
T |
C |
2: 77,246,316 (GRCm39) |
D237G |
probably benign |
Het |
|
| Other mutations in Ralgapa2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00666:Ralgapa2
|
APN |
2 |
146,327,056 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
IGL00915:Ralgapa2
|
APN |
2 |
146,184,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01012:Ralgapa2
|
APN |
2 |
146,263,659 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01018:Ralgapa2
|
APN |
2 |
146,252,112 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01018:Ralgapa2
|
APN |
2 |
146,252,113 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01902:Ralgapa2
|
APN |
2 |
146,156,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02160:Ralgapa2
|
APN |
2 |
146,190,360 (GRCm39) |
splice site |
probably benign |
|
|
IGL02321:Ralgapa2
|
APN |
2 |
146,254,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02412:Ralgapa2
|
APN |
2 |
146,254,052 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03026:Ralgapa2
|
APN |
2 |
146,302,695 (GRCm39) |
splice site |
probably benign |
|
|
IGL03115:Ralgapa2
|
APN |
2 |
146,266,734 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03256:Ralgapa2
|
APN |
2 |
146,302,632 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03379:Ralgapa2
|
APN |
2 |
146,199,907 (GRCm39) |
missense |
probably benign |
0.01 |
|
Chow
|
UTSW |
2 |
146,188,638 (GRCm39) |
nonsense |
probably null |
|
|
purina
|
UTSW |
2 |
146,175,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
P4748:Ralgapa2
|
UTSW |
2 |
146,188,731 (GRCm39) |
nonsense |
probably null |
|
|
R0012:Ralgapa2
|
UTSW |
2 |
146,254,672 (GRCm39) |
missense |
probably benign |
|
|
R0012:Ralgapa2
|
UTSW |
2 |
146,254,672 (GRCm39) |
missense |
probably benign |
|
|
R0165:Ralgapa2
|
UTSW |
2 |
146,230,407 (GRCm39) |
splice site |
probably benign |
|
|
R0344:Ralgapa2
|
UTSW |
2 |
146,188,714 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0402:Ralgapa2
|
UTSW |
2 |
146,276,729 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0419:Ralgapa2
|
UTSW |
2 |
146,270,592 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0638:Ralgapa2
|
UTSW |
2 |
146,184,112 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0704:Ralgapa2
|
UTSW |
2 |
146,293,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0722:Ralgapa2
|
UTSW |
2 |
146,230,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0866:Ralgapa2
|
UTSW |
2 |
146,277,923 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1065:Ralgapa2
|
UTSW |
2 |
146,292,478 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1212:Ralgapa2
|
UTSW |
2 |
146,199,902 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1395:Ralgapa2
|
UTSW |
2 |
146,230,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1614:Ralgapa2
|
UTSW |
2 |
146,230,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1686:Ralgapa2
|
UTSW |
2 |
146,199,920 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1905:Ralgapa2
|
UTSW |
2 |
146,229,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1956:Ralgapa2
|
UTSW |
2 |
146,302,679 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2144:Ralgapa2
|
UTSW |
2 |
146,230,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2148:Ralgapa2
|
UTSW |
2 |
146,273,807 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2219:Ralgapa2
|
UTSW |
2 |
146,263,599 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2220:Ralgapa2
|
UTSW |
2 |
146,263,599 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2261:Ralgapa2
|
UTSW |
2 |
146,184,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2402:Ralgapa2
|
UTSW |
2 |
146,195,112 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2495:Ralgapa2
|
UTSW |
2 |
146,203,320 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R3752:Ralgapa2
|
UTSW |
2 |
146,263,551 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3953:Ralgapa2
|
UTSW |
2 |
146,277,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3956:Ralgapa2
|
UTSW |
2 |
146,277,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4177:Ralgapa2
|
UTSW |
2 |
146,327,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4182:Ralgapa2
|
UTSW |
2 |
146,277,914 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4193:Ralgapa2
|
UTSW |
2 |
146,184,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4332:Ralgapa2
|
UTSW |
2 |
146,102,288 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4507:Ralgapa2
|
UTSW |
2 |
146,195,168 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4574:Ralgapa2
|
UTSW |
2 |
146,277,919 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4585:Ralgapa2
|
UTSW |
2 |
146,156,944 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4627:Ralgapa2
|
UTSW |
2 |
146,203,373 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4647:Ralgapa2
|
UTSW |
2 |
146,229,549 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R4677:Ralgapa2
|
UTSW |
2 |
146,187,387 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4724:Ralgapa2
|
UTSW |
2 |
146,187,453 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R4760:Ralgapa2
|
UTSW |
2 |
146,188,669 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4831:Ralgapa2
|
UTSW |
2 |
146,246,987 (GRCm39) |
intron |
probably benign |
|
|
R4962:Ralgapa2
|
UTSW |
2 |
146,276,754 (GRCm39) |
nonsense |
probably null |
|
|
R4993:Ralgapa2
|
UTSW |
2 |
146,289,231 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5041:Ralgapa2
|
UTSW |
2 |
146,327,071 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5120:Ralgapa2
|
UTSW |
2 |
146,254,004 (GRCm39) |
missense |
probably benign |
0.26 |
|
R5185:Ralgapa2
|
UTSW |
2 |
146,230,406 (GRCm39) |
splice site |
probably null |
|
|
R5393:Ralgapa2
|
UTSW |
2 |
146,187,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5428:Ralgapa2
|
UTSW |
2 |
146,176,414 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5439:Ralgapa2
|
UTSW |
2 |
146,184,430 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5476:Ralgapa2
|
UTSW |
2 |
146,289,356 (GRCm39) |
missense |
probably benign |
|
|
R5695:Ralgapa2
|
UTSW |
2 |
146,175,397 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5705:Ralgapa2
|
UTSW |
2 |
146,291,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5718:Ralgapa2
|
UTSW |
2 |
146,295,326 (GRCm39) |
splice site |
probably null |
|
|
R5817:Ralgapa2
|
UTSW |
2 |
146,175,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5877:Ralgapa2
|
UTSW |
2 |
146,230,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5994:Ralgapa2
|
UTSW |
2 |
146,203,373 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6048:Ralgapa2
|
UTSW |
2 |
146,276,765 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6158:Ralgapa2
|
UTSW |
2 |
146,266,596 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R6169:Ralgapa2
|
UTSW |
2 |
146,292,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6280:Ralgapa2
|
UTSW |
2 |
146,184,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6301:Ralgapa2
|
UTSW |
2 |
146,169,331 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6650:Ralgapa2
|
UTSW |
2 |
146,230,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6959:Ralgapa2
|
UTSW |
2 |
146,184,621 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7020:Ralgapa2
|
UTSW |
2 |
146,188,638 (GRCm39) |
nonsense |
probably null |
|
|
R7035:Ralgapa2
|
UTSW |
2 |
146,353,777 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7167:Ralgapa2
|
UTSW |
2 |
146,190,374 (GRCm39) |
missense |
probably benign |
|
|
R7186:Ralgapa2
|
UTSW |
2 |
146,230,406 (GRCm39) |
splice site |
probably null |
|
|
R7252:Ralgapa2
|
UTSW |
2 |
146,184,671 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7266:Ralgapa2
|
UTSW |
2 |
146,176,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7371:Ralgapa2
|
UTSW |
2 |
146,189,046 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7432:Ralgapa2
|
UTSW |
2 |
146,276,776 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7470:Ralgapa2
|
UTSW |
2 |
146,266,587 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7663:Ralgapa2
|
UTSW |
2 |
146,260,335 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7780:Ralgapa2
|
UTSW |
2 |
146,184,334 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7973:Ralgapa2
|
UTSW |
2 |
146,230,481 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8018:Ralgapa2
|
UTSW |
2 |
146,182,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8063:Ralgapa2
|
UTSW |
2 |
146,285,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8070:Ralgapa2
|
UTSW |
2 |
146,195,199 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8264:Ralgapa2
|
UTSW |
2 |
146,175,370 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8309:Ralgapa2
|
UTSW |
2 |
146,246,786 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R8409:Ralgapa2
|
UTSW |
2 |
146,086,897 (GRCm39) |
missense |
|
|
|
R8474:Ralgapa2
|
UTSW |
2 |
146,266,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8487:Ralgapa2
|
UTSW |
2 |
146,230,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8492:Ralgapa2
|
UTSW |
2 |
146,184,524 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8733:Ralgapa2
|
UTSW |
2 |
146,266,683 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8856:Ralgapa2
|
UTSW |
2 |
146,184,139 (GRCm39) |
missense |
probably benign |
0.30 |
|
R8858:Ralgapa2
|
UTSW |
2 |
146,102,285 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8862:Ralgapa2
|
UTSW |
2 |
146,266,731 (GRCm39) |
missense |
probably benign |
0.41 |
|
R9146:Ralgapa2
|
UTSW |
2 |
146,184,252 (GRCm39) |
missense |
probably benign |
|
|
R9324:Ralgapa2
|
UTSW |
2 |
146,302,645 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9439:Ralgapa2
|
UTSW |
2 |
146,254,058 (GRCm39) |
missense |
probably benign |
|
|
R9457:Ralgapa2
|
UTSW |
2 |
146,176,474 (GRCm39) |
missense |
probably damaging |
0.99 |
|
RF019:Ralgapa2
|
UTSW |
2 |
146,203,423 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
X0019:Ralgapa2
|
UTSW |
2 |
146,230,572 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
Z1088:Ralgapa2
|
UTSW |
2 |
146,276,825 (GRCm39) |
missense |
probably benign |
0.20 |
|
| Predicted Primers |
PCR Primer
(F):5'- TACGAAGAGCTGCAGGTTTG -3'
(R):5'- TGGTTCTTTAGCAGTCTGTTTCAAC -3'
Sequencing Primer
(F):5'- AGGTTTGGGCTCCTGAACAC -3'
(R):5'- GTGGATCTATGCTTTACAGGCCAAC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation