Incidental Mutation 'R1819:Tdrd6'
| ID |
204753 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tdrd6
|
| Ensembl Gene |
ENSMUSG00000040140 |
| Gene Name |
tudor domain containing 6 |
| Synonyms |
|
| MMRRC Submission |
039847-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1819 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
43926226-43941190 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 43937442 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Asparagine
at position 1202
(S1202N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000131277
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000045717]
[ENSMUST00000168073]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000045717
AA Change: S1202N
PolyPhen 2
Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)
|
| SMART Domains |
Protein: ENSMUSP00000035338
Gene: ENSMUSG00000040140
AA Change: S1202N
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TUDOR
|
14 |
133 |
9.9e-9 |
PFAM |
|
low complexity region
|
166 |
187 |
N/A |
INTRINSIC |
|
TUDOR
|
308 |
366 |
1.14e-2 |
SMART |
|
low complexity region
|
452 |
463 |
N/A |
INTRINSIC |
|
TUDOR
|
541 |
597 |
2.68e-8 |
SMART |
|
TUDOR
|
817 |
877 |
2.56e-5 |
SMART |
|
TUDOR
|
1037 |
1090 |
5.36e-8 |
SMART |
|
TUDOR
|
1357 |
1415 |
2.19e-13 |
SMART |
|
TUDOR
|
1569 |
1628 |
3.1e-13 |
SMART |
|
low complexity region
|
1826 |
1842 |
N/A |
INTRINSIC |
|
low complexity region
|
1866 |
1876 |
N/A |
INTRINSIC |
|
TUDOR
|
2026 |
2083 |
9.45e-1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000168073
AA Change: S1202N
PolyPhen 2
Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)
|
| SMART Domains |
Protein: ENSMUSP00000131277
Gene: ENSMUSG00000040140
AA Change: S1202N
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TUDOR
|
12 |
133 |
7.2e-9 |
PFAM |
|
low complexity region
|
166 |
187 |
N/A |
INTRINSIC |
|
TUDOR
|
308 |
366 |
1.14e-2 |
SMART |
|
low complexity region
|
452 |
463 |
N/A |
INTRINSIC |
|
TUDOR
|
541 |
597 |
2.68e-8 |
SMART |
|
TUDOR
|
817 |
877 |
2.56e-5 |
SMART |
|
TUDOR
|
1037 |
1090 |
5.36e-8 |
SMART |
|
TUDOR
|
1357 |
1415 |
2.19e-13 |
SMART |
|
TUDOR
|
1569 |
1628 |
3.1e-13 |
SMART |
|
low complexity region
|
1826 |
1842 |
N/A |
INTRINSIC |
|
low complexity region
|
1866 |
1876 |
N/A |
INTRINSIC |
|
TUDOR
|
2027 |
2084 |
9.45e-1 |
SMART |
|
| Meta Mutation Damage Score |
0.0723 |
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.1%
- 20x: 91.9%
|
| Validation Efficiency |
100% (91/91) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a tudor domain-containing protein and component of the chromatoid body, a type of ribonucleoprotein granule present in male germ cells. Studies in rodents have demonstrated a role for the encoded protein in spermiogenesis and the nonsense mediated decay (NMD) pathway. This protein is a major autoantigen in human patients with autoimmune polyendocrine syndrome type 1 (APS1). [provided by RefSeq, Oct 2016]
PHENOTYPE: Mice homozygous for a null allele exhibit male fertility associated with arrested spermatogenesis. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca8b |
T |
C |
11: 109,871,882 (GRCm39) |
|
probably null |
Het |
| Abhd17a |
T |
C |
10: 80,422,470 (GRCm39) |
T71A |
probably benign |
Het |
| Acad11 |
G |
A |
9: 103,991,738 (GRCm39) |
|
probably null |
Het |
| Adgrf1 |
C |
A |
17: 43,620,924 (GRCm39) |
T387K |
probably benign |
Het |
| Afdn |
A |
G |
17: 14,071,110 (GRCm39) |
T783A |
probably damaging |
Het |
| Akap13 |
T |
A |
7: 75,258,453 (GRCm39) |
M359K |
probably benign |
Het |
| Asxl3 |
A |
T |
18: 22,655,433 (GRCm39) |
N1148Y |
probably damaging |
Het |
| Atl1 |
T |
C |
12: 70,010,074 (GRCm39) |
S547P |
probably benign |
Het |
| Bace1 |
A |
T |
9: 45,768,460 (GRCm39) |
T252S |
possibly damaging |
Het |
| BC034090 |
A |
G |
1: 155,101,575 (GRCm39) |
S230P |
possibly damaging |
Het |
| Bnc2 |
A |
G |
4: 84,210,111 (GRCm39) |
F778L |
possibly damaging |
Het |
| Capn2 |
T |
A |
1: 182,300,162 (GRCm39) |
K609N |
probably benign |
Het |
| Capn8 |
T |
A |
1: 182,426,391 (GRCm39) |
I242N |
probably damaging |
Het |
| Car9 |
G |
T |
4: 43,512,439 (GRCm39) |
|
probably null |
Het |
| Ccdc180 |
A |
G |
4: 45,926,195 (GRCm39) |
E1135G |
possibly damaging |
Het |
| Ccdc181 |
C |
T |
1: 164,110,047 (GRCm39) |
Q385* |
probably null |
Het |
| Cdh10 |
G |
T |
15: 18,992,051 (GRCm39) |
G437* |
probably null |
Het |
| Ceacam1 |
T |
A |
7: 25,163,285 (GRCm39) |
Q316L |
possibly damaging |
Het |
| Cecr2 |
A |
G |
6: 120,708,228 (GRCm39) |
T77A |
probably damaging |
Het |
| Cers4 |
T |
A |
8: 4,571,232 (GRCm39) |
M267K |
probably benign |
Het |
| Csmd3 |
T |
C |
15: 47,617,131 (GRCm39) |
D1930G |
possibly damaging |
Het |
| Cyp2j11 |
A |
T |
4: 96,185,976 (GRCm39) |
V403D |
probably damaging |
Het |
| Cyp4v3 |
G |
A |
8: 45,768,673 (GRCm39) |
R296C |
possibly damaging |
Het |
| Ddx59 |
A |
G |
1: 136,360,245 (GRCm39) |
I420V |
probably damaging |
Het |
| Dnah5 |
T |
A |
15: 28,246,546 (GRCm39) |
L628* |
probably null |
Het |
| Dnah7a |
A |
C |
1: 53,598,307 (GRCm39) |
D1409E |
probably benign |
Het |
| Dus2 |
T |
A |
8: 106,778,480 (GRCm39) |
W377R |
probably damaging |
Het |
| E330034G19Rik |
A |
G |
14: 24,348,081 (GRCm39) |
D111G |
probably damaging |
Het |
| Erich4 |
C |
T |
7: 25,314,715 (GRCm39) |
R66Q |
possibly damaging |
Het |
| Fcgbp |
G |
T |
7: 27,784,708 (GRCm39) |
R256L |
probably benign |
Het |
| Fdxr |
A |
T |
11: 115,166,930 (GRCm39) |
F53Y |
probably damaging |
Het |
| Fkbp10 |
G |
T |
11: 100,306,715 (GRCm39) |
A36S |
probably benign |
Het |
| Foxo3 |
A |
T |
10: 42,073,607 (GRCm39) |
D84E |
probably benign |
Het |
| Gin1 |
A |
G |
1: 97,712,951 (GRCm39) |
|
probably null |
Het |
| Gli3 |
C |
T |
13: 15,900,377 (GRCm39) |
Q1255* |
probably null |
Het |
| Gm4847 |
T |
A |
1: 166,465,788 (GRCm39) |
H267L |
probably damaging |
Het |
| Gpr171 |
T |
C |
3: 59,005,341 (GRCm39) |
I145V |
probably benign |
Het |
| Gpr68 |
T |
A |
12: 100,844,662 (GRCm39) |
H294L |
possibly damaging |
Het |
| Gys2 |
T |
C |
6: 142,406,912 (GRCm39) |
E148G |
probably damaging |
Het |
| Heatr5b |
T |
C |
17: 79,098,940 (GRCm39) |
D1320G |
probably damaging |
Het |
| Ifnlr1 |
G |
T |
4: 135,413,834 (GRCm39) |
|
probably benign |
Het |
| Ift88 |
G |
A |
14: 57,692,976 (GRCm39) |
E392K |
probably damaging |
Het |
| Igsf9b |
T |
A |
9: 27,222,889 (GRCm39) |
S97T |
probably damaging |
Het |
| Il18rap |
A |
G |
1: 40,570,687 (GRCm39) |
I210V |
probably benign |
Het |
| Kcnj11 |
C |
T |
7: 45,748,580 (GRCm39) |
G248S |
probably benign |
Het |
| Kif28 |
T |
C |
1: 179,533,319 (GRCm39) |
K541E |
possibly damaging |
Het |
| Lilrb4a |
A |
G |
10: 51,372,124 (GRCm39) |
Y205C |
probably damaging |
Het |
| Lima1 |
T |
A |
15: 99,717,817 (GRCm39) |
H63L |
probably benign |
Het |
| Lonrf3 |
A |
G |
X: 35,622,361 (GRCm39) |
I687V |
probably damaging |
Het |
| Lrba |
A |
G |
3: 86,449,941 (GRCm39) |
T2099A |
possibly damaging |
Het |
| Morn5 |
C |
T |
2: 35,942,987 (GRCm39) |
T29M |
probably damaging |
Het |
| Neurl1b |
G |
A |
17: 26,657,674 (GRCm39) |
R22H |
probably benign |
Het |
| Nr2e3 |
T |
C |
9: 59,850,720 (GRCm39) |
I380V |
probably damaging |
Het |
| Oas1c |
G |
A |
5: 120,946,800 (GRCm39) |
A10V |
possibly damaging |
Het |
| Or1e35 |
T |
C |
11: 73,797,505 (GRCm39) |
E271G |
probably benign |
Het |
| Or52e8 |
C |
T |
7: 104,624,605 (GRCm39) |
V196I |
probably benign |
Het |
| P3h3 |
T |
C |
6: 124,831,895 (GRCm39) |
T297A |
probably benign |
Het |
| Pdpk1 |
T |
C |
17: 24,329,878 (GRCm39) |
K53E |
probably damaging |
Het |
| Plec |
C |
T |
15: 76,064,106 (GRCm39) |
R2056Q |
probably damaging |
Het |
| Plxna2 |
T |
A |
1: 194,472,494 (GRCm39) |
N1079K |
probably benign |
Het |
| Prr12 |
G |
C |
7: 44,698,121 (GRCm39) |
|
probably benign |
Het |
| Psip1 |
A |
G |
4: 83,376,400 (GRCm39) |
S480P |
probably benign |
Het |
| Ptpre |
A |
G |
7: 135,270,722 (GRCm39) |
|
probably benign |
Het |
| Pvalb |
A |
C |
15: 78,086,784 (GRCm39) |
V44G |
probably damaging |
Het |
| Rab3c |
T |
G |
13: 110,220,669 (GRCm39) |
Q164P |
possibly damaging |
Het |
| Rubcn |
T |
C |
16: 32,647,284 (GRCm39) |
K703R |
possibly damaging |
Het |
| Setd7 |
T |
G |
3: 51,450,060 (GRCm39) |
H122P |
probably benign |
Het |
| Slc26a8 |
A |
T |
17: 28,903,808 (GRCm39) |
F19I |
probably benign |
Het |
| Slc6a14 |
A |
G |
X: 21,607,286 (GRCm39) |
D625G |
probably benign |
Het |
| Snx6 |
C |
T |
12: 54,830,259 (GRCm39) |
V67I |
possibly damaging |
Het |
| Syngr3 |
A |
G |
17: 24,906,696 (GRCm39) |
F40L |
possibly damaging |
Het |
| Syt8 |
G |
A |
7: 141,991,971 (GRCm39) |
G21R |
possibly damaging |
Het |
| Tagln |
A |
G |
9: 45,842,138 (GRCm39) |
F152L |
probably benign |
Het |
| Tcf12 |
G |
A |
9: 72,016,999 (GRCm39) |
T36M |
probably damaging |
Het |
| Tekt2 |
T |
C |
4: 126,217,529 (GRCm39) |
K179E |
probably damaging |
Het |
| Tekt4 |
G |
T |
17: 25,692,785 (GRCm39) |
|
probably null |
Het |
| Tmprss5 |
G |
T |
9: 49,018,464 (GRCm39) |
R98L |
probably benign |
Het |
| Tns1 |
G |
T |
1: 73,955,635 (GRCm39) |
|
probably benign |
Het |
| Tpcn1 |
A |
C |
5: 120,674,292 (GRCm39) |
|
probably null |
Het |
| Ttc6 |
T |
C |
12: 57,741,286 (GRCm39) |
|
probably null |
Het |
| Ttf1 |
A |
G |
2: 28,964,796 (GRCm39) |
N706S |
possibly damaging |
Het |
| Washc4 |
C |
T |
10: 83,386,748 (GRCm39) |
T124I |
probably benign |
Het |
| Wdr17 |
A |
T |
8: 55,143,159 (GRCm39) |
S140T |
probably benign |
Het |
| Wdr19 |
A |
T |
5: 65,370,234 (GRCm39) |
I123F |
possibly damaging |
Het |
| Zer1 |
C |
T |
2: 30,000,230 (GRCm39) |
A317T |
probably benign |
Het |
| Zfp474 |
A |
G |
18: 52,771,872 (GRCm39) |
D175G |
probably damaging |
Het |
| Zfp598 |
T |
C |
17: 24,900,104 (GRCm39) |
|
probably benign |
Het |
| Zfp646 |
G |
A |
7: 127,482,292 (GRCm39) |
G1490S |
probably benign |
Het |
| Zranb3 |
A |
T |
1: 127,945,293 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Tdrd6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00571:Tdrd6
|
APN |
17 |
43,939,051 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL00844:Tdrd6
|
APN |
17 |
43,928,087 (GRCm39) |
missense |
probably benign |
|
|
IGL00845:Tdrd6
|
APN |
17 |
43,937,607 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL01558:Tdrd6
|
APN |
17 |
43,936,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01558:Tdrd6
|
APN |
17 |
43,935,657 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01575:Tdrd6
|
APN |
17 |
43,938,871 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01812:Tdrd6
|
APN |
17 |
43,936,065 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL02013:Tdrd6
|
APN |
17 |
43,936,837 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02067:Tdrd6
|
APN |
17 |
43,939,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02112:Tdrd6
|
APN |
17 |
43,940,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02159:Tdrd6
|
APN |
17 |
43,939,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02226:Tdrd6
|
APN |
17 |
43,938,093 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02416:Tdrd6
|
APN |
17 |
43,935,629 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL02577:Tdrd6
|
APN |
17 |
43,937,728 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02631:Tdrd6
|
APN |
17 |
43,937,110 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02738:Tdrd6
|
APN |
17 |
43,931,337 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02792:Tdrd6
|
APN |
17 |
43,935,918 (GRCm39) |
missense |
probably benign |
|
|
IGL02929:Tdrd6
|
APN |
17 |
43,940,604 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
IGL02934:Tdrd6
|
APN |
17 |
43,938,778 (GRCm39) |
missense |
probably benign |
0.42 |
|
IGL02954:Tdrd6
|
APN |
17 |
43,938,153 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL02969:Tdrd6
|
APN |
17 |
43,938,440 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03006:Tdrd6
|
APN |
17 |
43,936,323 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03155:Tdrd6
|
APN |
17 |
43,936,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03219:Tdrd6
|
APN |
17 |
43,938,855 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL03372:Tdrd6
|
APN |
17 |
43,936,459 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Edward
|
UTSW |
17 |
43,938,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
eliza
|
UTSW |
17 |
43,939,053 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
Elizabeth
|
UTSW |
17 |
43,935,095 (GRCm39) |
missense |
probably benign |
0.00 |
|
henry
|
UTSW |
17 |
43,939,050 (GRCm39) |
missense |
probably damaging |
0.99 |
|
BB001:Tdrd6
|
UTSW |
17 |
43,938,697 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
BB011:Tdrd6
|
UTSW |
17 |
43,938,697 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
G1citation:Tdrd6
|
UTSW |
17 |
43,938,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0030:Tdrd6
|
UTSW |
17 |
43,937,482 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0057:Tdrd6
|
UTSW |
17 |
43,928,052 (GRCm39) |
splice site |
probably benign |
|
|
R0090:Tdrd6
|
UTSW |
17 |
43,939,132 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0270:Tdrd6
|
UTSW |
17 |
43,935,199 (GRCm39) |
missense |
probably benign |
|
|
R0463:Tdrd6
|
UTSW |
17 |
43,936,452 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0594:Tdrd6
|
UTSW |
17 |
43,940,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0650:Tdrd6
|
UTSW |
17 |
43,939,050 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1226:Tdrd6
|
UTSW |
17 |
43,937,523 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1309:Tdrd6
|
UTSW |
17 |
43,937,512 (GRCm39) |
missense |
probably benign |
|
|
R1483:Tdrd6
|
UTSW |
17 |
43,938,498 (GRCm39) |
missense |
probably benign |
0.31 |
|
R1561:Tdrd6
|
UTSW |
17 |
43,936,515 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1574:Tdrd6
|
UTSW |
17 |
43,936,515 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1647:Tdrd6
|
UTSW |
17 |
43,938,000 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1648:Tdrd6
|
UTSW |
17 |
43,938,000 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1723:Tdrd6
|
UTSW |
17 |
43,939,218 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1786:Tdrd6
|
UTSW |
17 |
43,935,724 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1836:Tdrd6
|
UTSW |
17 |
43,936,480 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1892:Tdrd6
|
UTSW |
17 |
43,935,696 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1911:Tdrd6
|
UTSW |
17 |
43,937,979 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1936:Tdrd6
|
UTSW |
17 |
43,937,358 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2005:Tdrd6
|
UTSW |
17 |
43,939,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2006:Tdrd6
|
UTSW |
17 |
43,939,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2132:Tdrd6
|
UTSW |
17 |
43,935,724 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2133:Tdrd6
|
UTSW |
17 |
43,935,724 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3010:Tdrd6
|
UTSW |
17 |
43,938,933 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4225:Tdrd6
|
UTSW |
17 |
43,936,864 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4448:Tdrd6
|
UTSW |
17 |
43,940,626 (GRCm39) |
missense |
probably benign |
0.26 |
|
R4449:Tdrd6
|
UTSW |
17 |
43,940,626 (GRCm39) |
missense |
probably benign |
0.26 |
|
R4531:Tdrd6
|
UTSW |
17 |
43,939,645 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4624:Tdrd6
|
UTSW |
17 |
43,936,881 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4665:Tdrd6
|
UTSW |
17 |
43,935,007 (GRCm39) |
missense |
probably benign |
|
|
R4676:Tdrd6
|
UTSW |
17 |
43,938,501 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4785:Tdrd6
|
UTSW |
17 |
43,936,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4912:Tdrd6
|
UTSW |
17 |
43,935,218 (GRCm39) |
missense |
probably benign |
0.34 |
|
R5134:Tdrd6
|
UTSW |
17 |
43,937,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5145:Tdrd6
|
UTSW |
17 |
43,936,966 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5623:Tdrd6
|
UTSW |
17 |
43,940,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5712:Tdrd6
|
UTSW |
17 |
43,937,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5897:Tdrd6
|
UTSW |
17 |
43,935,768 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5913:Tdrd6
|
UTSW |
17 |
43,939,302 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R6142:Tdrd6
|
UTSW |
17 |
43,940,373 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6181:Tdrd6
|
UTSW |
17 |
43,939,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6195:Tdrd6
|
UTSW |
17 |
43,940,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6233:Tdrd6
|
UTSW |
17 |
43,940,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6289:Tdrd6
|
UTSW |
17 |
43,935,411 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6315:Tdrd6
|
UTSW |
17 |
43,937,229 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6578:Tdrd6
|
UTSW |
17 |
43,939,852 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R6645:Tdrd6
|
UTSW |
17 |
43,935,423 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6822:Tdrd6
|
UTSW |
17 |
43,938,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7000:Tdrd6
|
UTSW |
17 |
43,938,599 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7075:Tdrd6
|
UTSW |
17 |
43,936,065 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7107:Tdrd6
|
UTSW |
17 |
43,935,095 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7381:Tdrd6
|
UTSW |
17 |
43,936,984 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7458:Tdrd6
|
UTSW |
17 |
43,935,937 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7461:Tdrd6
|
UTSW |
17 |
43,938,817 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7505:Tdrd6
|
UTSW |
17 |
43,938,570 (GRCm39) |
missense |
not run |
|
|
R7583:Tdrd6
|
UTSW |
17 |
43,935,129 (GRCm39) |
missense |
probably benign |
0.29 |
|
R7613:Tdrd6
|
UTSW |
17 |
43,938,817 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7723:Tdrd6
|
UTSW |
17 |
43,936,851 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7759:Tdrd6
|
UTSW |
17 |
43,935,730 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7924:Tdrd6
|
UTSW |
17 |
43,938,697 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8002:Tdrd6
|
UTSW |
17 |
43,940,710 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8134:Tdrd6
|
UTSW |
17 |
43,937,064 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8231:Tdrd6
|
UTSW |
17 |
43,933,026 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8242:Tdrd6
|
UTSW |
17 |
43,939,821 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8542:Tdrd6
|
UTSW |
17 |
43,935,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8713:Tdrd6
|
UTSW |
17 |
43,935,910 (GRCm39) |
missense |
probably benign |
0.28 |
|
R9100:Tdrd6
|
UTSW |
17 |
43,936,305 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9201:Tdrd6
|
UTSW |
17 |
43,936,561 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9222:Tdrd6
|
UTSW |
17 |
43,939,231 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9369:Tdrd6
|
UTSW |
17 |
43,936,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9373:Tdrd6
|
UTSW |
17 |
43,939,053 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9384:Tdrd6
|
UTSW |
17 |
43,937,783 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9448:Tdrd6
|
UTSW |
17 |
43,936,567 (GRCm39) |
missense |
probably benign |
|
|
R9534:Tdrd6
|
UTSW |
17 |
43,936,510 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9613:Tdrd6
|
UTSW |
17 |
43,939,518 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0065:Tdrd6
|
UTSW |
17 |
43,936,884 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0065:Tdrd6
|
UTSW |
17 |
43,936,044 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
Z1088:Tdrd6
|
UTSW |
17 |
43,937,409 (GRCm39) |
missense |
probably benign |
0.23 |
|
Z1177:Tdrd6
|
UTSW |
17 |
43,938,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGTGAGCTGGCAAATATGTCTTC -3'
(R):5'- GTAGCCAAAGACCCAGATGG -3'
Sequencing Primer
(F):5'- TCTCCCTTGTTAATGGAAACCC -3'
(R):5'- GACTGATTATAGAGCTGTATGACGAC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation