Incidental Mutation 'R1837:Ylpm1'
| ID |
205427 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ylpm1
|
| Ensembl Gene |
ENSMUSG00000021244 |
| Gene Name |
YLP motif containing 1 |
| Synonyms |
A930013E17Rik, Zap3, ZAP |
| MMRRC Submission |
039864-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1837 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
12 |
| Chromosomal Location |
85043095-85117289 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 85076107 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 486
(V486A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000126347
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000021670]
[ENSMUST00000101202]
[ENSMUST00000164558]
[ENSMUST00000168977]
|
| AlphaFold |
Q9R0I7 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000021670
AA Change: V944A
PolyPhen 2
Score 0.862 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000021670
Gene: ENSMUSG00000021244
AA Change: V944A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
26 |
N/A |
INTRINSIC |
|
low complexity region
|
31 |
50 |
N/A |
INTRINSIC |
|
low complexity region
|
57 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
79 |
91 |
N/A |
INTRINSIC |
|
low complexity region
|
94 |
114 |
N/A |
INTRINSIC |
|
low complexity region
|
139 |
225 |
N/A |
INTRINSIC |
|
low complexity region
|
226 |
253 |
N/A |
INTRINSIC |
|
low complexity region
|
341 |
382 |
N/A |
INTRINSIC |
|
low complexity region
|
389 |
407 |
N/A |
INTRINSIC |
|
low complexity region
|
422 |
435 |
N/A |
INTRINSIC |
|
low complexity region
|
455 |
464 |
N/A |
INTRINSIC |
|
low complexity region
|
538 |
654 |
N/A |
INTRINSIC |
|
low complexity region
|
688 |
696 |
N/A |
INTRINSIC |
|
low complexity region
|
751 |
763 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
771 |
840 |
4.03e-5 |
PROSPERO |
|
low complexity region
|
841 |
854 |
N/A |
INTRINSIC |
|
low complexity region
|
966 |
972 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1062 |
1124 |
4.03e-5 |
PROSPERO |
|
low complexity region
|
1252 |
1266 |
N/A |
INTRINSIC |
|
low complexity region
|
1275 |
1293 |
N/A |
INTRINSIC |
|
low complexity region
|
1326 |
1338 |
N/A |
INTRINSIC |
|
low complexity region
|
1339 |
1353 |
N/A |
INTRINSIC |
|
low complexity region
|
1408 |
1425 |
N/A |
INTRINSIC |
|
coiled coil region
|
1447 |
1474 |
N/A |
INTRINSIC |
|
low complexity region
|
1494 |
1517 |
N/A |
INTRINSIC |
|
low complexity region
|
1518 |
1532 |
N/A |
INTRINSIC |
|
low complexity region
|
1536 |
1557 |
N/A |
INTRINSIC |
|
low complexity region
|
1598 |
1630 |
N/A |
INTRINSIC |
|
low complexity region
|
1678 |
1694 |
N/A |
INTRINSIC |
|
low complexity region
|
1705 |
1717 |
N/A |
INTRINSIC |
|
low complexity region
|
1720 |
1736 |
N/A |
INTRINSIC |
|
low complexity region
|
1797 |
1808 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
1829 |
1990 |
7.8e-11 |
PFAM |
|
coiled coil region
|
1995 |
2032 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000101202
|
| SMART Domains |
Protein: ENSMUSP00000098763
Gene: ENSMUSG00000021244
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
26 |
N/A |
INTRINSIC |
|
low complexity region
|
31 |
50 |
N/A |
INTRINSIC |
|
low complexity region
|
57 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
79 |
91 |
N/A |
INTRINSIC |
|
low complexity region
|
94 |
114 |
N/A |
INTRINSIC |
|
low complexity region
|
139 |
206 |
N/A |
INTRINSIC |
|
low complexity region
|
294 |
335 |
N/A |
INTRINSIC |
|
low complexity region
|
342 |
360 |
N/A |
INTRINSIC |
|
low complexity region
|
375 |
388 |
N/A |
INTRINSIC |
|
low complexity region
|
408 |
417 |
N/A |
INTRINSIC |
|
low complexity region
|
491 |
607 |
N/A |
INTRINSIC |
|
low complexity region
|
641 |
649 |
N/A |
INTRINSIC |
|
low complexity region
|
741 |
764 |
N/A |
INTRINSIC |
|
low complexity region
|
765 |
779 |
N/A |
INTRINSIC |
|
low complexity region
|
783 |
804 |
N/A |
INTRINSIC |
|
low complexity region
|
845 |
877 |
N/A |
INTRINSIC |
|
low complexity region
|
925 |
941 |
N/A |
INTRINSIC |
|
low complexity region
|
952 |
964 |
N/A |
INTRINSIC |
|
low complexity region
|
967 |
983 |
N/A |
INTRINSIC |
|
low complexity region
|
1044 |
1055 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
1076 |
1265 |
4.9e-11 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000164558
AA Change: V486A
PolyPhen 2
Score 0.923 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000126347
Gene: ENSMUSG00000021244
AA Change: V486A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
80 |
196 |
N/A |
INTRINSIC |
|
low complexity region
|
230 |
238 |
N/A |
INTRINSIC |
|
low complexity region
|
293 |
305 |
N/A |
INTRINSIC |
|
low complexity region
|
383 |
396 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
514 |
N/A |
INTRINSIC |
|
low complexity region
|
794 |
808 |
N/A |
INTRINSIC |
|
low complexity region
|
817 |
835 |
N/A |
INTRINSIC |
|
low complexity region
|
868 |
880 |
N/A |
INTRINSIC |
|
low complexity region
|
881 |
895 |
N/A |
INTRINSIC |
|
low complexity region
|
950 |
967 |
N/A |
INTRINSIC |
|
coiled coil region
|
989 |
1016 |
N/A |
INTRINSIC |
|
low complexity region
|
1036 |
1059 |
N/A |
INTRINSIC |
|
low complexity region
|
1060 |
1074 |
N/A |
INTRINSIC |
|
low complexity region
|
1078 |
1099 |
N/A |
INTRINSIC |
|
low complexity region
|
1140 |
1172 |
N/A |
INTRINSIC |
|
low complexity region
|
1220 |
1236 |
N/A |
INTRINSIC |
|
low complexity region
|
1247 |
1259 |
N/A |
INTRINSIC |
|
low complexity region
|
1262 |
1278 |
N/A |
INTRINSIC |
|
low complexity region
|
1339 |
1350 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
1371 |
1559 |
5.2e-11 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000168977
|
| SMART Domains |
Protein: ENSMUSP00000128962
Gene: ENSMUSG00000021244
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
26 |
N/A |
INTRINSIC |
|
low complexity region
|
31 |
50 |
N/A |
INTRINSIC |
|
low complexity region
|
57 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
79 |
91 |
N/A |
INTRINSIC |
|
low complexity region
|
94 |
114 |
N/A |
INTRINSIC |
|
low complexity region
|
139 |
225 |
N/A |
INTRINSIC |
|
low complexity region
|
226 |
253 |
N/A |
INTRINSIC |
|
low complexity region
|
341 |
382 |
N/A |
INTRINSIC |
|
low complexity region
|
389 |
407 |
N/A |
INTRINSIC |
|
low complexity region
|
422 |
435 |
N/A |
INTRINSIC |
|
low complexity region
|
455 |
464 |
N/A |
INTRINSIC |
|
low complexity region
|
538 |
654 |
N/A |
INTRINSIC |
|
low complexity region
|
688 |
696 |
N/A |
INTRINSIC |
|
low complexity region
|
788 |
811 |
N/A |
INTRINSIC |
|
low complexity region
|
812 |
826 |
N/A |
INTRINSIC |
|
low complexity region
|
830 |
851 |
N/A |
INTRINSIC |
|
low complexity region
|
892 |
924 |
N/A |
INTRINSIC |
|
low complexity region
|
972 |
988 |
N/A |
INTRINSIC |
|
low complexity region
|
999 |
1011 |
N/A |
INTRINSIC |
|
low complexity region
|
1014 |
1030 |
N/A |
INTRINSIC |
|
low complexity region
|
1091 |
1102 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
1123 |
1311 |
4.5e-11 |
PFAM |
|
| Meta Mutation Damage Score |
0.0609 |
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 94.9%
- 20x: 91.6%
|
| Validation Efficiency |
99% (86/87) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 85 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Actl10 |
G |
T |
2: 154,394,962 (GRCm39) |
G305W |
probably damaging |
Het |
| Actr3b |
A |
T |
5: 26,030,157 (GRCm39) |
T74S |
probably benign |
Het |
| Add2 |
A |
G |
6: 86,095,540 (GRCm39) |
E652G |
probably damaging |
Het |
| Alg9 |
T |
A |
9: 50,717,615 (GRCm39) |
V83D |
probably damaging |
Het |
| Atp13a2 |
T |
A |
4: 140,721,643 (GRCm39) |
Y244* |
probably null |
Het |
| BB014433 |
C |
G |
8: 15,092,629 (GRCm39) |
V75L |
unknown |
Het |
| Bcr |
A |
G |
10: 75,003,932 (GRCm39) |
|
probably benign |
Het |
| Begain |
G |
A |
12: 109,001,249 (GRCm39) |
|
probably benign |
Het |
| Bzw1 |
A |
G |
1: 58,439,277 (GRCm39) |
K67E |
probably damaging |
Het |
| Ccdc141 |
T |
C |
2: 76,842,009 (GRCm39) |
E1474G |
probably benign |
Het |
| Cdc73 |
T |
A |
1: 143,543,395 (GRCm39) |
T314S |
possibly damaging |
Het |
| Cfap206 |
T |
C |
4: 34,728,813 (GRCm39) |
T31A |
probably damaging |
Het |
| Cfap58 |
G |
A |
19: 48,017,578 (GRCm39) |
E813K |
probably damaging |
Het |
| Clstn2 |
C |
A |
9: 97,465,593 (GRCm39) |
A133S |
probably benign |
Het |
| Col14a1 |
A |
T |
15: 55,245,891 (GRCm39) |
D465V |
unknown |
Het |
| Col2a1 |
C |
T |
15: 97,894,522 (GRCm39) |
|
probably benign |
Het |
| Dab2 |
A |
G |
15: 6,365,957 (GRCm39) |
|
probably benign |
Het |
| Eme1 |
T |
C |
11: 94,536,787 (GRCm39) |
D464G |
probably benign |
Het |
| Eml6 |
T |
C |
11: 29,699,802 (GRCm39) |
|
probably null |
Het |
| Ern1 |
C |
A |
11: 106,349,783 (GRCm39) |
L44F |
probably damaging |
Het |
| Fam111a |
T |
A |
19: 12,564,816 (GRCm39) |
S188R |
probably benign |
Het |
| Fam151b |
A |
T |
13: 92,610,639 (GRCm39) |
|
probably benign |
Het |
| Fmo6 |
T |
C |
1: 162,750,379 (GRCm39) |
N226D |
probably benign |
Het |
| Ggt1 |
A |
G |
10: 75,415,128 (GRCm39) |
D214G |
probably benign |
Het |
| Gm14226 |
A |
G |
2: 154,866,930 (GRCm39) |
I296V |
probably benign |
Het |
| Gm9915 |
A |
T |
1: 42,269,847 (GRCm39) |
|
noncoding transcript |
Het |
| Heatr5b |
T |
C |
17: 79,128,180 (GRCm39) |
D485G |
possibly damaging |
Het |
| Helz2 |
A |
T |
2: 180,871,082 (GRCm39) |
I2785N |
probably damaging |
Het |
| Htt |
C |
T |
5: 34,976,367 (GRCm39) |
T723M |
probably benign |
Het |
| Hydin |
C |
A |
8: 111,296,257 (GRCm39) |
H3595Q |
probably benign |
Het |
| Il6ra |
T |
C |
3: 89,797,579 (GRCm39) |
D96G |
probably benign |
Het |
| Kif5a |
G |
A |
10: 127,072,684 (GRCm39) |
Q702* |
probably null |
Het |
| Klhdc7a |
G |
T |
4: 139,694,381 (GRCm39) |
P189T |
probably benign |
Het |
| Krt7 |
A |
G |
15: 101,317,463 (GRCm39) |
D252G |
probably benign |
Het |
| Lad1 |
C |
A |
1: 135,757,444 (GRCm39) |
D394E |
probably benign |
Het |
| Lhx8 |
A |
T |
3: 154,033,692 (GRCm39) |
C38S |
possibly damaging |
Het |
| Lta4h |
C |
T |
10: 93,305,037 (GRCm39) |
T280M |
probably damaging |
Het |
| Magi2 |
A |
T |
5: 20,670,825 (GRCm39) |
T163S |
probably damaging |
Het |
| Med1 |
G |
T |
11: 98,060,238 (GRCm39) |
D230E |
probably damaging |
Het |
| Mmp1b |
A |
T |
9: 7,386,409 (GRCm39) |
F171I |
probably damaging |
Het |
| Mprip |
T |
C |
11: 59,657,571 (GRCm39) |
V801A |
probably damaging |
Het |
| Mtrf1 |
A |
G |
14: 79,639,273 (GRCm39) |
E135G |
possibly damaging |
Het |
| Muc5ac |
T |
A |
7: 141,360,823 (GRCm39) |
M1378K |
probably benign |
Het |
| Myo3a |
A |
T |
2: 22,467,604 (GRCm39) |
Q286L |
possibly damaging |
Het |
| Ndor1 |
C |
T |
2: 25,138,408 (GRCm39) |
G391R |
probably damaging |
Het |
| Nefl |
C |
T |
14: 68,324,075 (GRCm39) |
R438C |
probably damaging |
Het |
| Nlrp3 |
G |
A |
11: 59,439,742 (GRCm39) |
V440I |
probably benign |
Het |
| Notch3 |
A |
T |
17: 32,343,296 (GRCm39) |
L1959Q |
probably damaging |
Het |
| Noto |
A |
G |
6: 85,401,159 (GRCm39) |
T63A |
probably benign |
Het |
| Oc90 |
G |
A |
15: 65,761,529 (GRCm39) |
T163M |
probably damaging |
Het |
| Or1l4 |
T |
A |
2: 37,092,114 (GRCm39) |
M287K |
probably benign |
Het |
| Or4c114 |
A |
T |
2: 88,905,176 (GRCm39) |
Y86* |
probably null |
Het |
| Or5an10 |
A |
G |
19: 12,275,740 (GRCm39) |
V252A |
probably damaging |
Het |
| Pdpr |
C |
A |
8: 111,861,366 (GRCm39) |
P787T |
probably damaging |
Het |
| Phlda1 |
A |
G |
10: 111,343,092 (GRCm39) |
Q276R |
probably benign |
Het |
| Ptpn21 |
T |
G |
12: 98,699,885 (GRCm39) |
K10Q |
probably damaging |
Het |
| Ptprb |
A |
G |
10: 116,177,531 (GRCm39) |
E1364G |
probably benign |
Het |
| Rabep1 |
T |
A |
11: 70,795,484 (GRCm39) |
W237R |
probably damaging |
Het |
| Rai1 |
A |
T |
11: 60,080,224 (GRCm39) |
K1429N |
probably damaging |
Het |
| Rapgef1 |
A |
G |
2: 29,627,438 (GRCm39) |
I1027M |
probably damaging |
Het |
| Rit1 |
C |
G |
3: 88,636,477 (GRCm39) |
T127S |
probably damaging |
Het |
| Rpap1 |
A |
C |
2: 119,600,366 (GRCm39) |
|
probably null |
Het |
| Senp7 |
T |
A |
16: 55,978,879 (GRCm39) |
C471S |
probably benign |
Het |
| Slc16a14 |
A |
G |
1: 84,890,120 (GRCm39) |
V395A |
probably benign |
Het |
| Slc45a1 |
C |
T |
4: 150,722,916 (GRCm39) |
G323S |
probably benign |
Het |
| Syne2 |
A |
T |
12: 76,014,434 (GRCm39) |
E3208D |
probably damaging |
Het |
| Tap1 |
C |
T |
17: 34,407,083 (GRCm39) |
A77V |
possibly damaging |
Het |
| Ticam1 |
T |
C |
17: 56,577,799 (GRCm39) |
E432G |
possibly damaging |
Het |
| Tmem192 |
C |
A |
8: 65,416,992 (GRCm39) |
|
probably benign |
Het |
| Trub1 |
T |
C |
19: 57,441,461 (GRCm39) |
V28A |
probably benign |
Het |
| Ttc21b |
A |
T |
2: 66,028,106 (GRCm39) |
L1121H |
probably benign |
Het |
| Ttc38 |
A |
G |
15: 85,735,764 (GRCm39) |
D290G |
probably damaging |
Het |
| Ulk1 |
C |
T |
5: 110,937,247 (GRCm39) |
G683D |
probably damaging |
Het |
| Vmn1r122 |
A |
T |
7: 20,867,291 (GRCm39) |
F255I |
probably benign |
Het |
| Vmn2r68 |
T |
A |
7: 84,882,886 (GRCm39) |
I289F |
probably damaging |
Het |
| Vps39 |
A |
T |
2: 120,155,878 (GRCm39) |
L514H |
probably damaging |
Het |
| Wdr48 |
T |
G |
9: 119,734,482 (GRCm39) |
S134A |
probably damaging |
Het |
| Yap1 |
A |
T |
9: 7,962,350 (GRCm39) |
Y139N |
probably damaging |
Het |
| Zbtb38 |
T |
C |
9: 96,569,048 (GRCm39) |
T679A |
probably benign |
Het |
| Zfp292 |
A |
G |
4: 34,810,264 (GRCm39) |
S927P |
probably damaging |
Het |
| Zfp324 |
C |
T |
7: 12,704,156 (GRCm39) |
T115I |
probably benign |
Het |
| Zfp523 |
T |
A |
17: 28,413,967 (GRCm39) |
I34N |
probably damaging |
Het |
| Zfp945 |
A |
T |
17: 23,070,247 (GRCm39) |
C551S |
probably damaging |
Het |
| Zfp958 |
A |
G |
8: 4,678,590 (GRCm39) |
H205R |
probably damaging |
Het |
| Zfp974 |
G |
A |
7: 27,609,781 (GRCm39) |
P648L |
possibly damaging |
Het |
|
| Other mutations in Ylpm1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00539:Ylpm1
|
APN |
12 |
85,075,728 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL00809:Ylpm1
|
APN |
12 |
85,095,968 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01508:Ylpm1
|
APN |
12 |
85,062,229 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
IGL02199:Ylpm1
|
APN |
12 |
85,080,779 (GRCm39) |
nonsense |
probably null |
|
|
IGL02392:Ylpm1
|
APN |
12 |
85,061,731 (GRCm39) |
missense |
unknown |
|
|
IGL02455:Ylpm1
|
APN |
12 |
85,077,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02506:Ylpm1
|
APN |
12 |
85,095,965 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03102:Ylpm1
|
APN |
12 |
85,096,032 (GRCm39) |
splice site |
probably benign |
|
|
I1329:Ylpm1
|
UTSW |
12 |
85,087,654 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02799:Ylpm1
|
UTSW |
12 |
85,091,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0010:Ylpm1
|
UTSW |
12 |
85,075,800 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0090:Ylpm1
|
UTSW |
12 |
85,075,814 (GRCm39) |
intron |
probably benign |
|
|
R0149:Ylpm1
|
UTSW |
12 |
85,075,612 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0226:Ylpm1
|
UTSW |
12 |
85,096,511 (GRCm39) |
missense |
probably benign |
0.21 |
|
R0375:Ylpm1
|
UTSW |
12 |
85,061,754 (GRCm39) |
missense |
unknown |
|
|
R0378:Ylpm1
|
UTSW |
12 |
85,043,850 (GRCm39) |
intron |
probably benign |
|
|
R0507:Ylpm1
|
UTSW |
12 |
85,075,886 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0742:Ylpm1
|
UTSW |
12 |
85,075,886 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1350:Ylpm1
|
UTSW |
12 |
85,060,856 (GRCm39) |
unclassified |
probably benign |
|
|
R1452:Ylpm1
|
UTSW |
12 |
85,077,157 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1500:Ylpm1
|
UTSW |
12 |
85,061,770 (GRCm39) |
missense |
unknown |
|
|
R1945:Ylpm1
|
UTSW |
12 |
85,062,192 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1971:Ylpm1
|
UTSW |
12 |
85,087,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2211:Ylpm1
|
UTSW |
12 |
85,091,152 (GRCm39) |
nonsense |
probably null |
|
|
R2213:Ylpm1
|
UTSW |
12 |
85,116,492 (GRCm39) |
missense |
probably benign |
0.25 |
|
R2269:Ylpm1
|
UTSW |
12 |
85,061,824 (GRCm39) |
missense |
unknown |
|
|
R2300:Ylpm1
|
UTSW |
12 |
85,107,093 (GRCm39) |
splice site |
probably null |
|
|
R2439:Ylpm1
|
UTSW |
12 |
85,060,891 (GRCm39) |
unclassified |
probably benign |
|
|
R2497:Ylpm1
|
UTSW |
12 |
85,043,535 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2890:Ylpm1
|
UTSW |
12 |
85,076,587 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3111:Ylpm1
|
UTSW |
12 |
85,076,145 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3436:Ylpm1
|
UTSW |
12 |
85,096,644 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3437:Ylpm1
|
UTSW |
12 |
85,096,644 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4156:Ylpm1
|
UTSW |
12 |
85,104,177 (GRCm39) |
intron |
probably benign |
|
|
R4157:Ylpm1
|
UTSW |
12 |
85,104,177 (GRCm39) |
intron |
probably benign |
|
|
R4959:Ylpm1
|
UTSW |
12 |
85,096,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5014:Ylpm1
|
UTSW |
12 |
85,061,523 (GRCm39) |
missense |
unknown |
|
|
R5039:Ylpm1
|
UTSW |
12 |
85,089,013 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5039:Ylpm1
|
UTSW |
12 |
85,062,267 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5084:Ylpm1
|
UTSW |
12 |
85,076,095 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5325:Ylpm1
|
UTSW |
12 |
85,060,735 (GRCm39) |
unclassified |
probably benign |
|
|
R5378:Ylpm1
|
UTSW |
12 |
85,077,029 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5428:Ylpm1
|
UTSW |
12 |
85,077,003 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5467:Ylpm1
|
UTSW |
12 |
85,043,633 (GRCm39) |
missense |
unknown |
|
|
R5605:Ylpm1
|
UTSW |
12 |
85,075,627 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5614:Ylpm1
|
UTSW |
12 |
85,111,718 (GRCm39) |
intron |
probably benign |
|
|
R5748:Ylpm1
|
UTSW |
12 |
85,107,025 (GRCm39) |
splice site |
probably null |
|
|
R5860:Ylpm1
|
UTSW |
12 |
85,087,660 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5861:Ylpm1
|
UTSW |
12 |
85,087,660 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5881:Ylpm1
|
UTSW |
12 |
85,088,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5909:Ylpm1
|
UTSW |
12 |
85,087,660 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5912:Ylpm1
|
UTSW |
12 |
85,087,660 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5915:Ylpm1
|
UTSW |
12 |
85,087,660 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6000:Ylpm1
|
UTSW |
12 |
85,044,030 (GRCm39) |
missense |
unknown |
|
|
R6004:Ylpm1
|
UTSW |
12 |
85,075,858 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R6007:Ylpm1
|
UTSW |
12 |
85,076,064 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6053:Ylpm1
|
UTSW |
12 |
85,043,277 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R6104:Ylpm1
|
UTSW |
12 |
85,076,404 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6197:Ylpm1
|
UTSW |
12 |
85,088,953 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6293:Ylpm1
|
UTSW |
12 |
85,062,051 (GRCm39) |
missense |
unknown |
|
|
R6297:Ylpm1
|
UTSW |
12 |
85,062,051 (GRCm39) |
missense |
unknown |
|
|
R6305:Ylpm1
|
UTSW |
12 |
85,077,319 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6379:Ylpm1
|
UTSW |
12 |
85,077,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6465:Ylpm1
|
UTSW |
12 |
85,096,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6608:Ylpm1
|
UTSW |
12 |
85,062,051 (GRCm39) |
missense |
unknown |
|
|
R6609:Ylpm1
|
UTSW |
12 |
85,062,051 (GRCm39) |
missense |
unknown |
|
|
R6737:Ylpm1
|
UTSW |
12 |
85,077,620 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6794:Ylpm1
|
UTSW |
12 |
85,043,655 (GRCm39) |
missense |
unknown |
|
|
R7383:Ylpm1
|
UTSW |
12 |
85,091,242 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7514:Ylpm1
|
UTSW |
12 |
85,077,268 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7577:Ylpm1
|
UTSW |
12 |
85,043,994 (GRCm39) |
missense |
unknown |
|
|
R7709:Ylpm1
|
UTSW |
12 |
85,059,799 (GRCm39) |
missense |
unknown |
|
|
R7718:Ylpm1
|
UTSW |
12 |
85,075,896 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7736:Ylpm1
|
UTSW |
12 |
85,059,757 (GRCm39) |
missense |
unknown |
|
|
R7758:Ylpm1
|
UTSW |
12 |
85,061,796 (GRCm39) |
missense |
unknown |
|
|
R7807:Ylpm1
|
UTSW |
12 |
85,060,855 (GRCm39) |
nonsense |
probably null |
|
|
R7838:Ylpm1
|
UTSW |
12 |
85,095,640 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7846:Ylpm1
|
UTSW |
12 |
85,104,042 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8170:Ylpm1
|
UTSW |
12 |
85,080,801 (GRCm39) |
missense |
probably benign |
0.40 |
|
R8776:Ylpm1
|
UTSW |
12 |
85,077,195 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8776-TAIL:Ylpm1
|
UTSW |
12 |
85,077,195 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8812:Ylpm1
|
UTSW |
12 |
85,043,566 (GRCm39) |
missense |
unknown |
|
|
R8847:Ylpm1
|
UTSW |
12 |
85,061,672 (GRCm39) |
missense |
unknown |
|
|
R8874:Ylpm1
|
UTSW |
12 |
85,116,394 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9129:Ylpm1
|
UTSW |
12 |
85,104,052 (GRCm39) |
missense |
|
|
|
R9165:Ylpm1
|
UTSW |
12 |
85,077,342 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9198:Ylpm1
|
UTSW |
12 |
85,080,689 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9564:Ylpm1
|
UTSW |
12 |
85,091,176 (GRCm39) |
missense |
probably benign |
0.30 |
|
R9629:Ylpm1
|
UTSW |
12 |
85,044,036 (GRCm39) |
missense |
unknown |
|
|
R9797:Ylpm1
|
UTSW |
12 |
85,077,109 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
Z1088:Ylpm1
|
UTSW |
12 |
85,076,929 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
Z1176:Ylpm1
|
UTSW |
12 |
85,077,058 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
Z1177:Ylpm1
|
UTSW |
12 |
85,104,057 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTCCGCAGATGTCAAGGATACC -3'
(R):5'- ACCTCTATATGATGAGCTGCTGC -3'
Sequencing Primer
(F):5'- TGTCAAGGATACCAAGGCAGCTC -3'
(R):5'- GATGAGCTGCTGCCTTTATTGCC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation