Incidental Mutation 'R1838:Adamtsl3'
| ID |
205496 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adamtsl3
|
| Ensembl Gene |
ENSMUSG00000070469 |
| Gene Name |
ADAMTS-like 3 |
| Synonyms |
9230119C12Rik, punctin-2 |
| MMRRC Submission |
039865-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1838 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
81984902-82263658 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 82142581 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Leucine
at position 267
(R267L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000133637
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000173287]
[ENSMUST00000173828]
|
| AlphaFold |
G3UXC7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000173287
AA Change: R267L
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000133637
Gene: ENSMUSG00000070469
AA Change: R267L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
38 |
N/A |
INTRINSIC |
|
TSP1
|
90 |
136 |
6.43e-8 |
SMART |
|
TSP1
|
355 |
414 |
1.59e-1 |
SMART |
|
TSP1
|
433 |
492 |
3.72e-4 |
SMART |
|
TSP1
|
494 |
547 |
4.28e-4 |
SMART |
|
TSP1
|
579 |
638 |
1.85e-2 |
SMART |
|
TSP1
|
660 |
717 |
1.75e-2 |
SMART |
|
TSP1
|
719 |
773 |
3.45e-8 |
SMART |
|
TSP1
|
775 |
833 |
3.67e-3 |
SMART |
|
TSP1
|
836 |
894 |
8.99e-2 |
SMART |
|
IGc2
|
938 |
1002 |
7.59e-4 |
SMART |
|
IG
|
1213 |
1296 |
4.87e0 |
SMART |
|
IGc2
|
1326 |
1388 |
1.01e-13 |
SMART |
|
TSP1
|
1441 |
1498 |
1.95e-2 |
SMART |
|
TSP1
|
1500 |
1559 |
6.76e-2 |
SMART |
|
TSP1
|
1616 |
1666 |
3.84e-1 |
SMART |
|
Pfam:PLAC
|
1674 |
1704 |
2.4e-11 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000173828
|
| SMART Domains |
Protein: ENSMUSP00000133337
Gene: ENSMUSG00000070469
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
Blast:IG
|
22 |
79 |
1e-26 |
BLAST |
|
SCOP:d1biha4
|
27 |
77 |
2e-5 |
SMART |
|
IG
|
283 |
366 |
4.87e0 |
SMART |
|
IGc2
|
396 |
458 |
1.01e-13 |
SMART |
|
TSP1
|
511 |
568 |
1.95e-2 |
SMART |
|
TSP1
|
570 |
629 |
6.76e-2 |
SMART |
|
TSP1
|
686 |
736 |
3.84e-1 |
SMART |
|
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.9%
- 10x: 95.2%
- 20x: 92.4%
|
| Validation Efficiency |
|
| Allele List at MGI |
All alleles(10) : Targeted(7) Gene trapped(2) Spontaneous(1)
|
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A630073D07Rik |
T |
C |
6: 132,603,690 (GRCm39) |
D22G |
unknown |
Het |
| Abca4 |
G |
A |
3: 121,921,954 (GRCm39) |
R1170K |
probably benign |
Het |
| Adam28 |
T |
C |
14: 68,876,659 (GRCm39) |
N197S |
possibly damaging |
Het |
| Adgrb2 |
A |
T |
4: 129,904,024 (GRCm39) |
T717S |
probably benign |
Het |
| Adgrb3 |
A |
G |
1: 25,123,351 (GRCm39) |
S1417P |
probably damaging |
Het |
| Afg3l2 |
A |
T |
18: 67,547,242 (GRCm39) |
V561D |
probably damaging |
Het |
| Atp13a2 |
T |
A |
4: 140,721,643 (GRCm39) |
Y244* |
probably null |
Het |
| BB014433 |
C |
G |
8: 15,092,629 (GRCm39) |
V75L |
unknown |
Het |
| Btnl6 |
T |
A |
17: 34,734,516 (GRCm39) |
D82V |
probably damaging |
Het |
| Ccdc178 |
A |
G |
18: 22,200,695 (GRCm39) |
Y421H |
probably damaging |
Het |
| Cdc123 |
A |
T |
2: 5,799,702 (GRCm39) |
|
probably null |
Het |
| Cdhr5 |
C |
T |
7: 140,852,516 (GRCm39) |
V367I |
possibly damaging |
Het |
| Celsr3 |
A |
G |
9: 108,707,105 (GRCm39) |
H1196R |
probably benign |
Het |
| Chd8 |
T |
C |
14: 52,442,340 (GRCm39) |
S2077G |
probably benign |
Het |
| Col6a5 |
G |
A |
9: 105,742,032 (GRCm39) |
H2296Y |
probably benign |
Het |
| Ctnna2 |
T |
C |
6: 77,822,525 (GRCm39) |
D26G |
probably damaging |
Het |
| Ctr9 |
G |
T |
7: 110,651,510 (GRCm39) |
R910L |
possibly damaging |
Het |
| Cyp2t4 |
G |
T |
7: 26,857,841 (GRCm39) |
R455L |
possibly damaging |
Het |
| Cyp3a13 |
A |
T |
5: 137,909,894 (GRCm39) |
|
probably null |
Het |
| Dennd3 |
T |
C |
15: 73,436,949 (GRCm39) |
S1059P |
probably damaging |
Het |
| Dennd4c |
A |
G |
4: 86,743,415 (GRCm39) |
T1135A |
probably benign |
Het |
| Dnah7b |
T |
C |
1: 46,155,337 (GRCm39) |
V295A |
probably benign |
Het |
| Dnah7b |
C |
A |
1: 46,316,265 (GRCm39) |
T3126K |
probably damaging |
Het |
| Ehbp1l1 |
C |
T |
19: 5,767,719 (GRCm39) |
E1195K |
probably benign |
Het |
| Exoc6b |
T |
A |
6: 84,830,660 (GRCm39) |
I447L |
probably benign |
Het |
| Glt1d1 |
G |
A |
5: 127,755,193 (GRCm39) |
V202I |
probably benign |
Het |
| Grk1 |
T |
C |
8: 13,466,155 (GRCm39) |
V533A |
possibly damaging |
Het |
| Gsdma3 |
C |
T |
11: 98,520,684 (GRCm39) |
A105V |
probably benign |
Het |
| Gzma |
T |
A |
13: 113,232,518 (GRCm39) |
I131F |
probably damaging |
Het |
| Helq |
A |
T |
5: 100,919,745 (GRCm39) |
L35* |
probably null |
Het |
| Hnrnpll |
T |
C |
17: 80,346,052 (GRCm39) |
N403S |
probably damaging |
Het |
| Hsf5 |
A |
G |
11: 87,526,881 (GRCm39) |
K518E |
probably benign |
Het |
| Ighe |
T |
A |
12: 113,235,470 (GRCm39) |
H258L |
unknown |
Het |
| Il6ra |
T |
C |
3: 89,797,579 (GRCm39) |
D96G |
probably benign |
Het |
| Ints13 |
C |
T |
6: 146,468,109 (GRCm39) |
A129T |
possibly damaging |
Het |
| Ipo7 |
T |
A |
7: 109,641,316 (GRCm39) |
H345Q |
probably damaging |
Het |
| Kcna2 |
A |
T |
3: 107,011,828 (GRCm39) |
E136D |
probably benign |
Het |
| Kif5a |
G |
A |
10: 127,072,684 (GRCm39) |
Q702* |
probably null |
Het |
| Klhdc7a |
G |
T |
4: 139,694,381 (GRCm39) |
P189T |
probably benign |
Het |
| Krtap4-9 |
A |
G |
11: 99,676,222 (GRCm39) |
|
probably benign |
Het |
| Lamc3 |
T |
C |
2: 31,815,594 (GRCm39) |
S1097P |
possibly damaging |
Het |
| Ldlrad2 |
A |
T |
4: 137,299,481 (GRCm39) |
N114K |
probably benign |
Het |
| Lrfn1 |
A |
T |
7: 28,159,193 (GRCm39) |
I371L |
probably damaging |
Het |
| Lrwd1 |
A |
G |
5: 136,161,242 (GRCm39) |
V240A |
probably benign |
Het |
| Lypd1 |
A |
T |
1: 125,801,108 (GRCm39) |
|
probably benign |
Het |
| Magi2 |
A |
T |
5: 20,670,825 (GRCm39) |
T163S |
probably damaging |
Het |
| Man2c1 |
A |
G |
9: 57,044,621 (GRCm39) |
N354S |
probably benign |
Het |
| Map3k13 |
T |
C |
16: 21,732,939 (GRCm39) |
Y514H |
possibly damaging |
Het |
| Med15 |
T |
C |
16: 17,471,426 (GRCm39) |
D577G |
probably benign |
Het |
| Mroh4 |
A |
T |
15: 74,487,962 (GRCm39) |
M320K |
probably benign |
Het |
| Ms4a10 |
T |
A |
19: 10,941,411 (GRCm39) |
D186V |
possibly damaging |
Het |
| Myh7 |
T |
C |
14: 55,210,637 (GRCm39) |
N1725S |
possibly damaging |
Het |
| Myo5c |
A |
T |
9: 75,180,835 (GRCm39) |
R741S |
probably damaging |
Het |
| Naa80 |
G |
A |
9: 107,460,216 (GRCm39) |
R37H |
possibly damaging |
Het |
| Naip6 |
T |
C |
13: 100,452,644 (GRCm39) |
D139G |
probably damaging |
Het |
| Or10s1 |
A |
T |
9: 39,985,605 (GRCm39) |
M5L |
probably benign |
Het |
| Or2p2 |
A |
T |
13: 21,256,595 (GRCm39) |
L292* |
probably null |
Het |
| Or4a79 |
A |
T |
2: 89,552,053 (GRCm39) |
M134K |
probably damaging |
Het |
| Or8g2 |
A |
T |
9: 39,821,137 (GRCm39) |
I13F |
possibly damaging |
Het |
| Pcdhb3 |
A |
G |
18: 37,434,370 (GRCm39) |
D112G |
probably benign |
Het |
| Pdpr |
C |
A |
8: 111,861,366 (GRCm39) |
P787T |
probably damaging |
Het |
| Pgm3 |
C |
T |
9: 86,451,286 (GRCm39) |
V123I |
probably benign |
Het |
| Pms1 |
A |
C |
1: 53,231,257 (GRCm39) |
|
probably null |
Het |
| Prl2b1 |
A |
G |
13: 27,572,549 (GRCm39) |
S14P |
possibly damaging |
Het |
| Prune2 |
T |
A |
19: 17,177,242 (GRCm39) |
W212R |
probably damaging |
Het |
| Rabgef1 |
A |
G |
5: 130,241,862 (GRCm39) |
E422G |
probably benign |
Het |
| Ralyl |
A |
G |
3: 14,208,472 (GRCm39) |
E204G |
probably damaging |
Het |
| Rbpms2 |
ACTGCTGCTGCTGCTGC |
ACTGCTGCTGCTGCTGCTGC |
9: 65,558,948 (GRCm39) |
|
probably benign |
Het |
| Rbpms2 |
TGCCGCCGCC |
TGCCGCCGCCGCC |
9: 65,558,962 (GRCm39) |
|
probably benign |
Het |
| Rit1 |
C |
G |
3: 88,636,477 (GRCm39) |
T127S |
probably damaging |
Het |
| Slc16a7 |
C |
T |
10: 125,067,067 (GRCm39) |
V191M |
probably damaging |
Het |
| Slc34a2 |
A |
T |
5: 53,215,778 (GRCm39) |
H63L |
probably benign |
Het |
| Smpd4 |
G |
A |
16: 17,460,166 (GRCm39) |
|
probably null |
Het |
| Sp3 |
A |
G |
2: 72,768,520 (GRCm39) |
S748P |
possibly damaging |
Het |
| Spata31d1b |
G |
A |
13: 59,863,671 (GRCm39) |
C273Y |
probably benign |
Het |
| Spata31d1b |
G |
A |
13: 59,865,279 (GRCm39) |
R809K |
probably benign |
Het |
| Tmco5 |
A |
T |
2: 116,711,360 (GRCm39) |
E90V |
probably damaging |
Het |
| Tnxb |
A |
T |
17: 34,897,884 (GRCm39) |
D844V |
probably damaging |
Het |
| Tpi1 |
T |
C |
6: 124,791,115 (GRCm39) |
T41A |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,557,536 (GRCm39) |
I29853V |
probably damaging |
Het |
| Vmn2r26 |
C |
T |
6: 124,001,730 (GRCm39) |
T5I |
probably benign |
Het |
| Wdr95 |
A |
G |
5: 149,522,831 (GRCm39) |
D663G |
probably benign |
Het |
| Zbtb39 |
T |
C |
10: 127,578,569 (GRCm39) |
F381S |
probably damaging |
Het |
| Zfp523 |
T |
A |
17: 28,413,967 (GRCm39) |
I34N |
probably damaging |
Het |
| Zfp646 |
T |
A |
7: 127,478,911 (GRCm39) |
Y363N |
probably damaging |
Het |
| Zfp712 |
A |
C |
13: 67,190,111 (GRCm39) |
C139G |
probably damaging |
Het |
| Zfp958 |
A |
G |
8: 4,678,590 (GRCm39) |
H205R |
probably damaging |
Het |
| Zfp974 |
G |
A |
7: 27,609,781 (GRCm39) |
P648L |
possibly damaging |
Het |
|
| Other mutations in Adamtsl3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01549:Adamtsl3
|
APN |
7 |
82,261,656 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01936:Adamtsl3
|
APN |
7 |
82,244,579 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL02819:Adamtsl3
|
APN |
7 |
82,223,329 (GRCm39) |
missense |
probably damaging |
0.99 |
|
P0012:Adamtsl3
|
UTSW |
7 |
82,223,465 (GRCm39) |
missense |
probably benign |
0.27 |
|
R0096:Adamtsl3
|
UTSW |
7 |
82,114,907 (GRCm39) |
intron |
probably benign |
|
|
R0096:Adamtsl3
|
UTSW |
7 |
82,114,907 (GRCm39) |
intron |
probably benign |
|
|
R0180:Adamtsl3
|
UTSW |
7 |
82,225,198 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0270:Adamtsl3
|
UTSW |
7 |
82,206,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0295:Adamtsl3
|
UTSW |
7 |
82,197,213 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0329:Adamtsl3
|
UTSW |
7 |
82,171,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0330:Adamtsl3
|
UTSW |
7 |
82,171,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0548:Adamtsl3
|
UTSW |
7 |
82,178,191 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0611:Adamtsl3
|
UTSW |
7 |
82,178,120 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0671:Adamtsl3
|
UTSW |
7 |
82,172,390 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0711:Adamtsl3
|
UTSW |
7 |
82,114,907 (GRCm39) |
intron |
probably benign |
|
|
R0845:Adamtsl3
|
UTSW |
7 |
82,225,204 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1119:Adamtsl3
|
UTSW |
7 |
82,189,525 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1458:Adamtsl3
|
UTSW |
7 |
82,172,528 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1644:Adamtsl3
|
UTSW |
7 |
82,099,298 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1691:Adamtsl3
|
UTSW |
7 |
82,148,814 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2131:Adamtsl3
|
UTSW |
7 |
82,227,802 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2245:Adamtsl3
|
UTSW |
7 |
82,099,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2274:Adamtsl3
|
UTSW |
7 |
82,255,766 (GRCm39) |
missense |
probably benign |
0.37 |
|
R2275:Adamtsl3
|
UTSW |
7 |
82,255,766 (GRCm39) |
missense |
probably benign |
0.37 |
|
R2448:Adamtsl3
|
UTSW |
7 |
82,148,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3725:Adamtsl3
|
UTSW |
7 |
82,261,612 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R3757:Adamtsl3
|
UTSW |
7 |
81,986,415 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3821:Adamtsl3
|
UTSW |
7 |
82,255,687 (GRCm39) |
splice site |
probably benign |
|
|
R4618:Adamtsl3
|
UTSW |
7 |
82,255,728 (GRCm39) |
missense |
probably benign |
0.41 |
|
R4842:Adamtsl3
|
UTSW |
7 |
82,178,069 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4887:Adamtsl3
|
UTSW |
7 |
82,223,822 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4888:Adamtsl3
|
UTSW |
7 |
82,223,822 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4925:Adamtsl3
|
UTSW |
7 |
82,251,507 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4960:Adamtsl3
|
UTSW |
7 |
82,216,185 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5026:Adamtsl3
|
UTSW |
7 |
82,225,262 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5152:Adamtsl3
|
UTSW |
7 |
82,223,752 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5198:Adamtsl3
|
UTSW |
7 |
82,261,006 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5244:Adamtsl3
|
UTSW |
7 |
82,247,277 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5281:Adamtsl3
|
UTSW |
7 |
82,178,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5323:Adamtsl3
|
UTSW |
7 |
82,206,269 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5523:Adamtsl3
|
UTSW |
7 |
82,223,650 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5602:Adamtsl3
|
UTSW |
7 |
82,206,447 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5638:Adamtsl3
|
UTSW |
7 |
82,260,958 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5682:Adamtsl3
|
UTSW |
7 |
82,255,758 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5782:Adamtsl3
|
UTSW |
7 |
82,189,494 (GRCm39) |
splice site |
probably null |
|
|
R5946:Adamtsl3
|
UTSW |
7 |
82,225,265 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6091:Adamtsl3
|
UTSW |
7 |
82,114,829 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6258:Adamtsl3
|
UTSW |
7 |
82,178,191 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6500:Adamtsl3
|
UTSW |
7 |
82,227,818 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6765:Adamtsl3
|
UTSW |
7 |
82,216,232 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R6785:Adamtsl3
|
UTSW |
7 |
82,171,212 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6982:Adamtsl3
|
UTSW |
7 |
82,164,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7109:Adamtsl3
|
UTSW |
7 |
82,261,069 (GRCm39) |
missense |
|
|
|
R7341:Adamtsl3
|
UTSW |
7 |
82,206,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7402:Adamtsl3
|
UTSW |
7 |
82,227,825 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7506:Adamtsl3
|
UTSW |
7 |
82,164,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7549:Adamtsl3
|
UTSW |
7 |
82,223,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7575:Adamtsl3
|
UTSW |
7 |
82,223,756 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7592:Adamtsl3
|
UTSW |
7 |
81,986,459 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7617:Adamtsl3
|
UTSW |
7 |
82,206,054 (GRCm39) |
splice site |
probably null |
|
|
R7654:Adamtsl3
|
UTSW |
7 |
82,223,702 (GRCm39) |
missense |
probably benign |
|
|
R7721:Adamtsl3
|
UTSW |
7 |
82,255,728 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R7784:Adamtsl3
|
UTSW |
7 |
82,223,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7858:Adamtsl3
|
UTSW |
7 |
82,099,371 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8109:Adamtsl3
|
UTSW |
7 |
82,251,487 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8125:Adamtsl3
|
UTSW |
7 |
82,099,541 (GRCm39) |
splice site |
probably null |
|
|
R8211:Adamtsl3
|
UTSW |
7 |
82,172,371 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8348:Adamtsl3
|
UTSW |
7 |
82,253,007 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8360:Adamtsl3
|
UTSW |
7 |
82,197,187 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8448:Adamtsl3
|
UTSW |
7 |
82,253,007 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8465:Adamtsl3
|
UTSW |
7 |
82,247,330 (GRCm39) |
missense |
probably benign |
0.43 |
|
R8547:Adamtsl3
|
UTSW |
7 |
82,077,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8551:Adamtsl3
|
UTSW |
7 |
82,189,678 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8558:Adamtsl3
|
UTSW |
7 |
82,077,600 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R8709:Adamtsl3
|
UTSW |
7 |
82,077,642 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8722:Adamtsl3
|
UTSW |
7 |
82,244,745 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8930:Adamtsl3
|
UTSW |
7 |
82,261,069 (GRCm39) |
missense |
|
|
|
R8932:Adamtsl3
|
UTSW |
7 |
82,261,069 (GRCm39) |
missense |
|
|
|
R9131:Adamtsl3
|
UTSW |
7 |
82,244,722 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9169:Adamtsl3
|
UTSW |
7 |
82,223,188 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9272:Adamtsl3
|
UTSW |
7 |
82,189,753 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9276:Adamtsl3
|
UTSW |
7 |
82,206,710 (GRCm39) |
intron |
probably benign |
|
|
R9351:Adamtsl3
|
UTSW |
7 |
82,169,929 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9352:Adamtsl3
|
UTSW |
7 |
82,091,656 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9749:Adamtsl3
|
UTSW |
7 |
82,099,394 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9750:Adamtsl3
|
UTSW |
7 |
82,244,589 (GRCm39) |
missense |
probably benign |
0.11 |
|
RF005:Adamtsl3
|
UTSW |
7 |
82,261,603 (GRCm39) |
missense |
|
|
|
X0003:Adamtsl3
|
UTSW |
7 |
82,260,967 (GRCm39) |
nonsense |
probably null |
|
|
X0063:Adamtsl3
|
UTSW |
7 |
82,223,365 (GRCm39) |
missense |
probably benign |
0.25 |
|
Z1088:Adamtsl3
|
UTSW |
7 |
82,189,533 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Adamtsl3
|
UTSW |
7 |
82,148,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AATGCCTTACCTGCAGGGAC -3'
(R):5'- CATACTGTATATTCCTGGACTCTGAG -3'
Sequencing Primer
(F):5'- TAAATGCCCGTGTGAGTCC -3'
(R):5'- CTCTGAGTATGGTGGACAGAAATCCC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation