Incidental Mutation 'R1840:Kirrel1'
| ID |
205673 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Kirrel1
|
| Ensembl Gene |
ENSMUSG00000041734 |
| Gene Name |
kirre like nephrin family adhesion molecule 1 |
| Synonyms |
6720469N11Rik, Neph1, Kirrel1, Kirrel |
| MMRRC Submission |
039866-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1840 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
86985900-87082054 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 86996458 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Isoleucine
at position 380
(M380I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000125525
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041732]
[ENSMUST00000107618]
[ENSMUST00000159976]
|
| AlphaFold |
Q80W68 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000041732
AA Change: M380I
PolyPhen 2
Score 0.461 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000043756
Gene: ENSMUSG00000041734
AA Change: M380I
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000107618
AA Change: M380I
PolyPhen 2
Score 0.461 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000103243
Gene: ENSMUSG00000041734
AA Change: M380I
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
low complexity region
|
694 |
712 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000159976
AA Change: M380I
PolyPhen 2
Score 0.461 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000125525
Gene: ENSMUSG00000041734
AA Change: M380I
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
low complexity region
|
694 |
712 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0922 |
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.8%
- 10x: 95.2%
- 20x: 92.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2; MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Mice homozygous for a gene trap insertion exhibit postnatal lethality and are small and sickly. Glomerular and tubular defects in the kidney result in severe proteinuria. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(121) : Targeted, other(2) Gene trapped(119) |
| Other mutations in this stock |
Total: 118 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2510009E07Rik |
T |
A |
16: 21,472,236 (GRCm39) |
M85L |
probably benign |
Het |
| Aatk |
T |
G |
11: 119,904,558 (GRCm39) |
D206A |
probably damaging |
Het |
| Agap3 |
A |
G |
5: 24,705,229 (GRCm39) |
D719G |
probably damaging |
Het |
| Agrn |
G |
A |
4: 156,251,872 (GRCm39) |
R1797C |
probably damaging |
Het |
| Ascc3 |
T |
A |
10: 50,566,257 (GRCm39) |
M734K |
probably benign |
Het |
| Asph |
T |
A |
4: 9,601,340 (GRCm39) |
M136L |
possibly damaging |
Het |
| Atm |
A |
T |
9: 53,367,830 (GRCm39) |
V2431E |
probably damaging |
Het |
| Atp2b1 |
A |
G |
10: 98,858,791 (GRCm39) |
H1158R |
probably benign |
Het |
| Atxn7l1 |
A |
G |
12: 33,421,032 (GRCm39) |
|
probably null |
Het |
| BC024139 |
G |
T |
15: 76,004,842 (GRCm39) |
S611R |
probably benign |
Het |
| Becn1 |
C |
T |
11: 101,186,392 (GRCm39) |
G105S |
probably damaging |
Het |
| Bud13 |
A |
G |
9: 46,197,706 (GRCm39) |
E70G |
probably damaging |
Het |
| Cacul1 |
A |
T |
19: 60,522,688 (GRCm39) |
L282* |
probably null |
Het |
| Catspere2 |
A |
G |
1: 177,830,581 (GRCm39) |
D30G |
possibly damaging |
Het |
| Ccar1 |
T |
A |
10: 62,599,289 (GRCm39) |
K614M |
probably damaging |
Het |
| Cd96 |
T |
C |
16: 45,919,455 (GRCm39) |
T189A |
probably benign |
Het |
| Cdh5 |
C |
A |
8: 104,853,248 (GRCm39) |
Y189* |
probably null |
Het |
| Chka |
A |
G |
19: 3,936,460 (GRCm39) |
N284S |
probably benign |
Het |
| Cntn6 |
A |
T |
6: 104,751,441 (GRCm39) |
I366F |
probably damaging |
Het |
| Csmd3 |
C |
T |
15: 47,470,560 (GRCm39) |
G3372E |
probably damaging |
Het |
| Cyp4f16 |
T |
C |
17: 32,761,980 (GRCm39) |
|
probably null |
Het |
| Dcaf6 |
A |
G |
1: 165,227,317 (GRCm39) |
V270A |
probably damaging |
Het |
| Ddx60 |
T |
A |
8: 62,422,587 (GRCm39) |
I608N |
probably damaging |
Het |
| Dnah9 |
A |
T |
11: 65,725,024 (GRCm39) |
C1849* |
probably null |
Het |
| Eci3 |
C |
A |
13: 35,144,024 (GRCm39) |
V34L |
probably benign |
Het |
| Eif1ad9 |
T |
C |
12: 88,296,181 (GRCm39) |
V53A |
probably benign |
Het |
| Entrep2 |
C |
A |
7: 64,408,943 (GRCm39) |
V484L |
probably benign |
Het |
| Epha1 |
C |
T |
6: 42,340,522 (GRCm39) |
R583H |
probably damaging |
Het |
| Erbin |
A |
T |
13: 103,971,455 (GRCm39) |
N720K |
probably benign |
Het |
| Eya1 |
T |
A |
1: 14,299,728 (GRCm39) |
R346* |
probably null |
Het |
| Fhdc1 |
G |
A |
3: 84,353,128 (GRCm39) |
T699I |
possibly damaging |
Het |
| Flvcr2 |
T |
C |
12: 85,849,995 (GRCm39) |
V427A |
possibly damaging |
Het |
| Frey1 |
T |
C |
2: 92,213,554 (GRCm39) |
S36P |
probably benign |
Het |
| Fzd9 |
T |
A |
5: 135,278,425 (GRCm39) |
T487S |
probably benign |
Het |
| Gas2l3 |
T |
C |
10: 89,258,113 (GRCm39) |
Y160C |
possibly damaging |
Het |
| Gm10269 |
T |
C |
18: 20,815,866 (GRCm39) |
K52R |
probably damaging |
Het |
| Gm8674 |
A |
T |
13: 50,055,801 (GRCm39) |
|
noncoding transcript |
Het |
| Gpr61 |
A |
G |
3: 108,057,797 (GRCm39) |
V288A |
possibly damaging |
Het |
| Gramd4 |
T |
C |
15: 86,014,393 (GRCm39) |
|
probably null |
Het |
| Gtpbp4 |
A |
G |
13: 9,029,500 (GRCm39) |
L403P |
probably benign |
Het |
| H6pd |
A |
T |
4: 150,066,507 (GRCm39) |
D626E |
possibly damaging |
Het |
| Herc6 |
T |
A |
6: 57,635,091 (GRCm39) |
L769* |
probably null |
Het |
| Hes5 |
A |
G |
4: 155,045,711 (GRCm39) |
K58R |
probably damaging |
Het |
| Heyl |
A |
G |
4: 123,135,183 (GRCm39) |
I59V |
probably damaging |
Het |
| Hpca |
A |
G |
4: 129,012,393 (GRCm39) |
F48L |
probably damaging |
Het |
| Ice1 |
C |
T |
13: 70,754,337 (GRCm39) |
R583Q |
probably benign |
Het |
| Ints2 |
C |
T |
11: 86,123,911 (GRCm39) |
G626R |
probably damaging |
Het |
| Kansl1l |
T |
A |
1: 66,817,191 (GRCm39) |
I390F |
probably damaging |
Het |
| Kat5 |
C |
T |
19: 5,659,266 (GRCm39) |
V95M |
possibly damaging |
Het |
| Kcnh4 |
T |
A |
11: 100,636,167 (GRCm39) |
I827F |
possibly damaging |
Het |
| Kif1b |
C |
T |
4: 149,272,589 (GRCm39) |
R138Q |
probably damaging |
Het |
| Lats1 |
T |
A |
10: 7,586,703 (GRCm39) |
L955* |
probably null |
Het |
| Ldlrad2 |
A |
C |
4: 137,299,495 (GRCm39) |
C110G |
possibly damaging |
Het |
| Lgi3 |
G |
A |
14: 70,772,216 (GRCm39) |
|
probably null |
Het |
| Lingo1 |
A |
G |
9: 56,527,842 (GRCm39) |
M249T |
probably benign |
Het |
| Lrig3 |
A |
T |
10: 125,849,258 (GRCm39) |
R993* |
probably null |
Het |
| Lsm14b |
T |
A |
2: 179,668,521 (GRCm39) |
I74N |
probably damaging |
Het |
| Lyplal1 |
T |
A |
1: 185,832,414 (GRCm39) |
I114F |
probably damaging |
Het |
| Mmp15 |
A |
G |
8: 96,092,048 (GRCm39) |
Y86C |
probably damaging |
Het |
| Myh2 |
A |
G |
11: 67,077,313 (GRCm39) |
E816G |
probably benign |
Het |
| Myo5c |
A |
G |
9: 75,157,017 (GRCm39) |
N151S |
probably damaging |
Het |
| Nckap1 |
T |
A |
2: 80,332,594 (GRCm39) |
E1082V |
possibly damaging |
Het |
| Nrg4 |
A |
C |
9: 55,189,890 (GRCm39) |
|
probably benign |
Het |
| Nrp2 |
T |
C |
1: 62,777,498 (GRCm39) |
L101P |
probably damaging |
Het |
| Or14j5 |
A |
T |
17: 38,161,639 (GRCm39) |
D52V |
probably damaging |
Het |
| Or2at1 |
A |
T |
7: 99,416,803 (GRCm39) |
T145S |
probably benign |
Het |
| Or4p19 |
T |
C |
2: 88,242,411 (GRCm39) |
D197G |
probably benign |
Het |
| Or51q1c |
A |
G |
7: 103,653,324 (GRCm39) |
I281V |
probably benign |
Het |
| Or5ak22 |
G |
A |
2: 85,230,512 (GRCm39) |
R122C |
probably benign |
Het |
| Parp14 |
T |
A |
16: 35,683,819 (GRCm39) |
E169V |
probably damaging |
Het |
| Pcolce2 |
A |
T |
9: 95,552,256 (GRCm39) |
N130Y |
probably benign |
Het |
| Pcolce2 |
G |
A |
9: 95,552,170 (GRCm39) |
R101H |
probably damaging |
Het |
| Plscr1 |
A |
T |
9: 92,140,127 (GRCm39) |
S5C |
unknown |
Het |
| Plxdc2 |
T |
C |
2: 16,674,667 (GRCm39) |
V338A |
probably benign |
Het |
| Psg23 |
T |
A |
7: 18,344,363 (GRCm39) |
N364I |
possibly damaging |
Het |
| Psmg4 |
A |
G |
13: 34,362,039 (GRCm39) |
E109G |
probably damaging |
Het |
| Ptk2 |
T |
C |
15: 73,082,733 (GRCm39) |
E908G |
probably damaging |
Het |
| Ptpn14 |
G |
A |
1: 189,519,048 (GRCm39) |
R26H |
probably damaging |
Het |
| Ranbp2 |
T |
A |
10: 58,314,588 (GRCm39) |
N1769K |
probably benign |
Het |
| Rbm14 |
C |
T |
19: 4,851,823 (GRCm39) |
|
probably benign |
Het |
| Rgs7 |
A |
T |
1: 174,980,714 (GRCm39) |
D103E |
probably damaging |
Het |
| Rmnd5a |
G |
A |
6: 71,375,439 (GRCm39) |
L80F |
probably benign |
Het |
| Rock2 |
T |
A |
12: 16,978,990 (GRCm39) |
D93E |
probably benign |
Het |
| Rps6ka6 |
A |
G |
X: 110,330,629 (GRCm39) |
I246T |
possibly damaging |
Het |
| Rubcn |
T |
C |
16: 32,646,542 (GRCm39) |
M803V |
possibly damaging |
Het |
| Ryr3 |
T |
C |
2: 112,581,165 (GRCm39) |
Y2889C |
probably damaging |
Het |
| Sall2 |
T |
C |
14: 52,551,182 (GRCm39) |
N671S |
probably damaging |
Het |
| Selplg |
T |
C |
5: 113,957,905 (GRCm39) |
T134A |
possibly damaging |
Het |
| Sez6 |
C |
A |
11: 77,844,543 (GRCm39) |
T122N |
possibly damaging |
Het |
| Slc9b1 |
T |
A |
3: 135,063,229 (GRCm39) |
D4E |
unknown |
Het |
| Smim18 |
A |
G |
8: 34,232,376 (GRCm39) |
M81T |
probably benign |
Het |
| Snap91 |
A |
T |
9: 86,697,518 (GRCm39) |
H281Q |
probably damaging |
Het |
| Sparc |
C |
A |
11: 55,286,692 (GRCm39) |
C302F |
probably damaging |
Het |
| Spg11 |
A |
G |
2: 121,932,237 (GRCm39) |
L535P |
probably damaging |
Het |
| Spsb1 |
G |
A |
4: 149,991,088 (GRCm39) |
T160I |
probably damaging |
Het |
| Stra6 |
A |
G |
9: 58,047,813 (GRCm39) |
N128S |
probably benign |
Het |
| Strc |
T |
C |
2: 121,209,777 (GRCm39) |
E182G |
probably damaging |
Het |
| Sult2a6 |
A |
G |
7: 13,988,754 (GRCm39) |
M2T |
probably benign |
Het |
| Sv2c |
T |
C |
13: 96,118,352 (GRCm39) |
N499S |
probably benign |
Het |
| Szt2 |
A |
T |
4: 118,222,854 (GRCm39) |
|
probably benign |
Het |
| Tbx20 |
A |
T |
9: 24,636,972 (GRCm39) |
S372T |
probably benign |
Het |
| Tcp11l2 |
T |
A |
10: 84,440,463 (GRCm39) |
S289T |
probably damaging |
Het |
| Tdrd1 |
A |
G |
19: 56,830,744 (GRCm39) |
E259G |
probably damaging |
Het |
| Thsd7a |
T |
A |
6: 12,330,973 (GRCm39) |
I1390L |
probably benign |
Het |
| Tln2 |
G |
A |
9: 67,249,325 (GRCm39) |
R921W |
probably damaging |
Het |
| Tmem126a |
C |
A |
7: 90,102,092 (GRCm39) |
G36* |
probably null |
Het |
| Tmem245 |
C |
T |
4: 56,903,947 (GRCm39) |
V606I |
probably benign |
Het |
| Trpm6 |
A |
G |
19: 18,843,631 (GRCm39) |
D1665G |
probably benign |
Het |
| Ubac2 |
T |
G |
14: 122,231,674 (GRCm39) |
V200G |
probably benign |
Het |
| Ubr5 |
G |
A |
15: 37,981,161 (GRCm39) |
A2372V |
possibly damaging |
Het |
| Ugcg |
C |
T |
4: 59,219,517 (GRCm39) |
P285S |
probably damaging |
Het |
| Vmn1r9 |
T |
C |
6: 57,048,522 (GRCm39) |
V199A |
probably damaging |
Het |
| Vmn2r118 |
T |
A |
17: 55,917,406 (GRCm39) |
K369* |
probably null |
Het |
| Xpnpep3 |
G |
T |
15: 81,311,554 (GRCm39) |
A87S |
probably benign |
Het |
| Zc3h7a |
C |
T |
16: 10,978,890 (GRCm39) |
R95H |
probably damaging |
Het |
| Zdhhc11 |
A |
G |
13: 74,122,771 (GRCm39) |
N169S |
probably damaging |
Het |
| Zfp62 |
T |
A |
11: 49,107,215 (GRCm39) |
D435E |
probably damaging |
Het |
| Zfyve16 |
T |
C |
13: 92,648,033 (GRCm39) |
D1007G |
possibly damaging |
Het |
|
| Other mutations in Kirrel1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01310:Kirrel1
|
APN |
3 |
86,997,182 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL01865:Kirrel1
|
APN |
3 |
86,993,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01875:Kirrel1
|
APN |
3 |
87,003,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02337:Kirrel1
|
APN |
3 |
86,996,519 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL02724:Kirrel1
|
APN |
3 |
86,997,780 (GRCm39) |
nonsense |
probably null |
|
|
IGL02825:Kirrel1
|
APN |
3 |
86,996,595 (GRCm39) |
splice site |
probably benign |
|
|
IGL02826:Kirrel1
|
APN |
3 |
86,995,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03102:Kirrel1
|
APN |
3 |
86,990,807 (GRCm39) |
missense |
probably damaging |
0.98 |
|
D4043:Kirrel1
|
UTSW |
3 |
86,990,510 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0360:Kirrel1
|
UTSW |
3 |
86,997,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0364:Kirrel1
|
UTSW |
3 |
86,997,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0421:Kirrel1
|
UTSW |
3 |
86,990,914 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0503:Kirrel1
|
UTSW |
3 |
87,005,109 (GRCm39) |
missense |
probably benign |
0.20 |
|
R1112:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1116:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1144:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1147:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1147:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1190:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1226:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1501:Kirrel1
|
UTSW |
3 |
86,997,779 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1538:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1546:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1628:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1630:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1631:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1664:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1671:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1695:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1769:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1807:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1808:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1876:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1995:Kirrel1
|
UTSW |
3 |
87,003,093 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2014:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2086:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2108:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2354:Kirrel1
|
UTSW |
3 |
86,995,792 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2407:Kirrel1
|
UTSW |
3 |
86,992,150 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2904:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2905:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2958:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2959:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2960:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2961:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3026:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3028:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3034:Kirrel1
|
UTSW |
3 |
86,990,746 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R3149:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3195:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3196:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3499:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3699:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3720:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3721:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3788:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3793:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3876:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3877:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3901:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3910:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3911:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3912:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3913:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3930:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3931:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4022:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4067:Kirrel1
|
UTSW |
3 |
86,995,774 (GRCm39) |
nonsense |
probably null |
|
|
R4077:Kirrel1
|
UTSW |
3 |
86,992,387 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4198:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4328:Kirrel1
|
UTSW |
3 |
86,992,081 (GRCm39) |
intron |
probably benign |
|
|
R4355:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4363:Kirrel1
|
UTSW |
3 |
86,997,792 (GRCm39) |
nonsense |
probably null |
|
|
R4378:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4386:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4460:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4468:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4469:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4650:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4652:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4734:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4748:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4749:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R5304:Kirrel1
|
UTSW |
3 |
86,996,902 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5534:Kirrel1
|
UTSW |
3 |
86,997,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5604:Kirrel1
|
UTSW |
3 |
86,996,462 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7199:Kirrel1
|
UTSW |
3 |
86,990,695 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7221:Kirrel1
|
UTSW |
3 |
86,993,704 (GRCm39) |
nonsense |
probably null |
|
|
R7284:Kirrel1
|
UTSW |
3 |
86,990,694 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7332:Kirrel1
|
UTSW |
3 |
86,995,705 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7369:Kirrel1
|
UTSW |
3 |
87,048,391 (GRCm39) |
missense |
probably benign |
0.20 |
|
R7371:Kirrel1
|
UTSW |
3 |
86,995,729 (GRCm39) |
missense |
probably benign |
0.44 |
|
R7508:Kirrel1
|
UTSW |
3 |
86,990,746 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R7566:Kirrel1
|
UTSW |
3 |
86,995,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7567:Kirrel1
|
UTSW |
3 |
87,002,988 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7621:Kirrel1
|
UTSW |
3 |
86,995,528 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R8030:Kirrel1
|
UTSW |
3 |
87,005,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8141:Kirrel1
|
UTSW |
3 |
86,993,735 (GRCm39) |
nonsense |
probably null |
|
|
R8261:Kirrel1
|
UTSW |
3 |
86,995,309 (GRCm39) |
intron |
probably benign |
|
|
R8477:Kirrel1
|
UTSW |
3 |
86,992,138 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8512:Kirrel1
|
UTSW |
3 |
86,995,534 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8954:Kirrel1
|
UTSW |
3 |
86,997,173 (GRCm39) |
missense |
probably benign |
0.25 |
|
R8987:Kirrel1
|
UTSW |
3 |
86,992,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9058:Kirrel1
|
UTSW |
3 |
86,992,442 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9146:Kirrel1
|
UTSW |
3 |
87,003,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9311:Kirrel1
|
UTSW |
3 |
87,005,123 (GRCm39) |
missense |
probably benign |
0.29 |
|
R9527:Kirrel1
|
UTSW |
3 |
86,996,912 (GRCm39) |
nonsense |
probably null |
|
|
R9629:Kirrel1
|
UTSW |
3 |
87,003,025 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Kirrel1
|
UTSW |
3 |
86,991,182 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ACCCTGAGTTCTATGCAAGTC -3'
(R):5'- AGCTGATGATTCTCAGGCACC -3'
Sequencing Primer
(F):5'- TATGGCTGACTGCAAGTACC -3'
(R):5'- TCAGGCACCTGAGACTCTGAC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation