Incidental Mutation 'R1823:Myocd'
| ID |
206587 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myocd
|
| Ensembl Gene |
ENSMUSG00000020542 |
| Gene Name |
myocardin |
| Synonyms |
Srfcp |
| MMRRC Submission |
039851-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1823 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
65067387-65160815 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 65069496 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Isoleucine
at position 909
(M909I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000104335
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000101042]
[ENSMUST00000102635]
[ENSMUST00000108695]
|
| AlphaFold |
Q8VIM5 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000101042
AA Change: M781I
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000098603
Gene: ENSMUSG00000020542
AA Change: M781I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
19 |
32 |
N/A |
INTRINSIC |
|
low complexity region
|
119 |
132 |
N/A |
INTRINSIC |
|
SCOP:d1lsha3
|
140 |
221 |
4e-3 |
SMART |
|
SAP
|
252 |
286 |
1.29e-8 |
SMART |
|
low complexity region
|
326 |
343 |
N/A |
INTRINSIC |
|
low complexity region
|
371 |
383 |
N/A |
INTRINSIC |
|
coiled coil region
|
396 |
435 |
N/A |
INTRINSIC |
|
low complexity region
|
557 |
573 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
629 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000102635
AA Change: M861I
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000099695
Gene: ENSMUSG00000020542
AA Change: M861I
| Domain | Start | End | E-Value | Type |
|---|
|
RPEL
|
18 |
43 |
4e-1 |
SMART |
|
RPEL
|
62 |
87 |
9.26e0 |
SMART |
|
RPEL
|
106 |
131 |
1.15e-6 |
SMART |
|
low complexity region
|
147 |
160 |
N/A |
INTRINSIC |
|
low complexity region
|
247 |
260 |
N/A |
INTRINSIC |
|
SCOP:d1lsha3
|
268 |
349 |
4e-3 |
SMART |
|
SAP
|
380 |
414 |
1.29e-8 |
SMART |
|
low complexity region
|
454 |
471 |
N/A |
INTRINSIC |
|
low complexity region
|
499 |
511 |
N/A |
INTRINSIC |
|
coiled coil region
|
524 |
563 |
N/A |
INTRINSIC |
|
low complexity region
|
695 |
709 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108695
AA Change: M909I
PolyPhen 2
Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)
|
| SMART Domains |
Protein: ENSMUSP00000104335
Gene: ENSMUSG00000020542
AA Change: M909I
| Domain | Start | End | E-Value | Type |
|---|
|
RPEL
|
18 |
43 |
4e-1 |
SMART |
|
RPEL
|
62 |
87 |
9.26e0 |
SMART |
|
RPEL
|
106 |
131 |
1.15e-6 |
SMART |
|
low complexity region
|
147 |
160 |
N/A |
INTRINSIC |
|
low complexity region
|
247 |
260 |
N/A |
INTRINSIC |
|
SCOP:d1lsha3
|
268 |
349 |
5e-3 |
SMART |
|
SAP
|
380 |
414 |
1.29e-8 |
SMART |
|
low complexity region
|
454 |
471 |
N/A |
INTRINSIC |
|
low complexity region
|
499 |
511 |
N/A |
INTRINSIC |
|
coiled coil region
|
524 |
563 |
N/A |
INTRINSIC |
|
low complexity region
|
685 |
701 |
N/A |
INTRINSIC |
|
low complexity region
|
743 |
757 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000151483
|
| Meta Mutation Damage Score |
0.0861 |
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.1%
- 20x: 91.6%
|
| Validation Efficiency |
98% (87/89) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a nuclear protein, which is expressed in heart, aorta, and in smooth muscle cell-containing tissues. It functions as a transcriptional co-activator of serum response factor (SRF) and modulates expression of cardiac and smooth muscle-specific SRF-target genes, and thus may play a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
PHENOTYPE: Mice homozygous for a null mutation exhibit embryonic lethality and fail to form vascular smooth muscle. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 85 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adcy1 |
G |
A |
11: 7,111,312 (GRCm39) |
V868I |
probably benign |
Het |
| Ahnak |
G |
T |
19: 8,982,269 (GRCm39) |
M1184I |
probably damaging |
Het |
| Akap11 |
T |
C |
14: 78,748,928 (GRCm39) |
E1153G |
probably damaging |
Het |
| Amy1 |
T |
C |
3: 113,356,376 (GRCm39) |
N260S |
probably null |
Het |
| Ankrd6 |
A |
G |
4: 32,824,427 (GRCm39) |
L129P |
probably damaging |
Het |
| Aox1 |
A |
T |
1: 58,351,518 (GRCm39) |
T702S |
probably benign |
Het |
| Apobec1 |
G |
T |
6: 122,555,845 (GRCm39) |
T204K |
possibly damaging |
Het |
| Arhgef19 |
A |
G |
4: 140,976,457 (GRCm39) |
R433G |
probably benign |
Het |
| Atf6b |
T |
A |
17: 34,867,618 (GRCm39) |
H110Q |
possibly damaging |
Het |
| Btnl4 |
C |
T |
17: 34,694,826 (GRCm39) |
|
probably null |
Het |
| Camsap2 |
T |
C |
1: 136,201,521 (GRCm39) |
T662A |
possibly damaging |
Het |
| Cbs |
G |
A |
17: 31,843,245 (GRCm39) |
H229Y |
probably damaging |
Het |
| Cct8 |
G |
A |
16: 87,287,442 (GRCm39) |
R111* |
probably null |
Het |
| Cdc42bpb |
C |
T |
12: 111,293,993 (GRCm39) |
A250T |
probably damaging |
Het |
| Chrd |
A |
G |
16: 20,560,097 (GRCm39) |
|
probably benign |
Het |
| Ckap2l |
A |
G |
2: 129,117,499 (GRCm39) |
F559L |
probably damaging |
Het |
| Cltrn |
A |
G |
X: 162,901,230 (GRCm39) |
D184G |
possibly damaging |
Het |
| D630003M21Rik |
T |
C |
2: 158,059,477 (GRCm39) |
Y141C |
probably damaging |
Het |
| Dbf4 |
T |
C |
5: 8,447,539 (GRCm39) |
N557S |
probably benign |
Het |
| Dct |
T |
G |
14: 118,273,935 (GRCm39) |
N324T |
probably benign |
Het |
| Dip2a |
A |
T |
10: 76,114,336 (GRCm39) |
L999* |
probably null |
Het |
| Dock10 |
T |
A |
1: 80,520,814 (GRCm39) |
|
probably null |
Het |
| Dync2li1 |
A |
T |
17: 84,957,225 (GRCm39) |
D330V |
probably damaging |
Het |
| Eif4g3 |
T |
A |
4: 137,907,802 (GRCm39) |
D1267E |
probably benign |
Het |
| Enc1 |
A |
G |
13: 97,382,486 (GRCm39) |
E332G |
possibly damaging |
Het |
| Fat2 |
C |
T |
11: 55,147,606 (GRCm39) |
V3879I |
probably benign |
Het |
| Fh1 |
A |
T |
1: 175,444,114 (GRCm39) |
I117K |
probably damaging |
Het |
| Fkbp15 |
A |
G |
4: 62,255,328 (GRCm39) |
L227P |
probably damaging |
Het |
| Fpr1 |
T |
A |
17: 18,097,315 (GRCm39) |
M225L |
probably benign |
Het |
| Fras1 |
A |
T |
5: 96,918,547 (GRCm39) |
I3528F |
probably damaging |
Het |
| Grm7 |
A |
G |
6: 111,184,730 (GRCm39) |
T354A |
probably benign |
Het |
| Ift27 |
T |
A |
15: 78,057,978 (GRCm39) |
I9F |
possibly damaging |
Het |
| Igf1r |
A |
G |
7: 67,844,729 (GRCm39) |
D834G |
possibly damaging |
Het |
| Igsf9b |
T |
A |
9: 27,243,028 (GRCm39) |
L738Q |
probably damaging |
Het |
| Itgam |
A |
T |
7: 127,663,904 (GRCm39) |
T44S |
probably benign |
Het |
| Ivd |
T |
A |
2: 118,692,515 (GRCm39) |
I5N |
probably benign |
Het |
| Jcad |
T |
C |
18: 4,675,780 (GRCm39) |
S1181P |
probably damaging |
Het |
| Kctd18 |
A |
G |
1: 57,995,524 (GRCm39) |
V251A |
probably benign |
Het |
| Mycbp2 |
A |
G |
14: 103,489,945 (GRCm39) |
V953A |
possibly damaging |
Het |
| Myo18a |
T |
C |
11: 77,715,923 (GRCm39) |
|
probably benign |
Het |
| Myo3a |
A |
T |
2: 22,345,091 (GRCm39) |
Y509F |
probably damaging |
Het |
| Ndufv3 |
G |
A |
17: 31,750,219 (GRCm39) |
R467Q |
probably damaging |
Het |
| Nkpd1 |
G |
A |
7: 19,257,177 (GRCm39) |
V319M |
probably damaging |
Het |
| Or13p4 |
T |
A |
4: 118,547,389 (GRCm39) |
N87Y |
probably damaging |
Het |
| Or1af1 |
T |
C |
2: 37,110,344 (GRCm39) |
V281A |
probably damaging |
Het |
| Or1p1c |
C |
T |
11: 74,161,043 (GRCm39) |
A276V |
probably damaging |
Het |
| Or2q1 |
G |
T |
6: 42,795,202 (GRCm39) |
A266S |
possibly damaging |
Het |
| Or2t1 |
T |
A |
14: 14,328,774 (GRCm38) |
L221Q |
probably damaging |
Het |
| Or4c111 |
A |
G |
2: 88,843,722 (GRCm39) |
S229P |
probably benign |
Het |
| Or5b101 |
C |
A |
19: 13,005,181 (GRCm39) |
V171L |
probably benign |
Het |
| Parp4 |
T |
C |
14: 56,827,329 (GRCm39) |
|
probably benign |
Het |
| Pcdhb9 |
A |
G |
18: 37,535,871 (GRCm39) |
T622A |
probably benign |
Het |
| Pdpk1 |
A |
T |
17: 24,317,150 (GRCm39) |
|
probably benign |
Het |
| Pkhd1 |
C |
A |
1: 20,417,681 (GRCm39) |
G2490V |
probably damaging |
Het |
| Plekhg1 |
G |
T |
10: 3,853,658 (GRCm39) |
|
probably null |
Het |
| Plekhh2 |
A |
G |
17: 84,882,617 (GRCm39) |
Y708C |
probably damaging |
Het |
| Pnp |
T |
C |
14: 51,187,786 (GRCm39) |
F107L |
probably damaging |
Het |
| Postn |
T |
A |
3: 54,292,708 (GRCm39) |
|
probably null |
Het |
| Prcp |
A |
T |
7: 92,577,883 (GRCm39) |
D349V |
probably damaging |
Het |
| Prl3a1 |
A |
T |
13: 27,454,177 (GRCm39) |
I52F |
probably damaging |
Het |
| Pym1 |
G |
A |
10: 128,601,913 (GRCm39) |
|
probably benign |
Het |
| Rad9a |
A |
T |
19: 4,247,241 (GRCm39) |
I248N |
probably damaging |
Het |
| Ror2 |
T |
G |
13: 53,264,341 (GRCm39) |
E917A |
probably benign |
Het |
| Rsf1 |
G |
A |
7: 97,229,117 (GRCm39) |
|
probably benign |
Het |
| Sema6d |
A |
G |
2: 124,501,476 (GRCm39) |
|
probably null |
Het |
| Shisal1 |
T |
C |
15: 84,290,669 (GRCm39) |
T213A |
probably benign |
Het |
| Slc4a2 |
C |
T |
5: 24,632,618 (GRCm39) |
A12V |
probably damaging |
Het |
| Slco6b1 |
T |
G |
1: 96,888,901 (GRCm39) |
|
noncoding transcript |
Het |
| Slf2 |
A |
T |
19: 44,923,687 (GRCm39) |
H167L |
possibly damaging |
Het |
| Snx9 |
G |
T |
17: 5,970,946 (GRCm39) |
G429V |
probably damaging |
Het |
| Sod3 |
G |
T |
5: 52,525,504 (GRCm39) |
V68L |
probably benign |
Het |
| Spta1 |
T |
A |
1: 174,074,115 (GRCm39) |
D2351E |
probably benign |
Het |
| Srpk3 |
G |
A |
X: 72,821,561 (GRCm39) |
R425Q |
possibly damaging |
Het |
| Tatdn1 |
C |
T |
15: 58,788,005 (GRCm39) |
G171E |
probably damaging |
Het |
| Tbc1d22a |
T |
C |
15: 86,119,770 (GRCm39) |
V22A |
possibly damaging |
Het |
| Tnfsf9 |
A |
G |
17: 57,412,738 (GRCm39) |
T103A |
probably benign |
Het |
| Tpm3-rs7 |
T |
C |
14: 113,552,595 (GRCm39) |
L163P |
possibly damaging |
Het |
| Trim52 |
T |
A |
14: 106,344,401 (GRCm39) |
C20S |
probably damaging |
Het |
| Ucp1 |
C |
T |
8: 84,020,661 (GRCm39) |
T157I |
probably damaging |
Het |
| Uspl1 |
T |
A |
5: 149,151,224 (GRCm39) |
L794Q |
probably benign |
Het |
| Vmn1r5 |
T |
A |
6: 56,962,580 (GRCm39) |
V85E |
probably damaging |
Het |
| Vmn1r58 |
A |
G |
7: 5,413,405 (GRCm39) |
I275T |
possibly damaging |
Het |
| Vmn2r79 |
A |
G |
7: 86,687,080 (GRCm39) |
I820M |
probably damaging |
Het |
| Wscd1 |
C |
A |
11: 71,651,044 (GRCm39) |
P124T |
probably benign |
Het |
| Zfp780b |
A |
T |
7: 27,662,525 (GRCm39) |
C677S |
possibly damaging |
Het |
|
| Other mutations in Myocd |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00092:Myocd
|
APN |
11 |
65,071,770 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL00481:Myocd
|
APN |
11 |
65,077,980 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00857:Myocd
|
APN |
11 |
65,069,662 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL01012:Myocd
|
APN |
11 |
65,075,451 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL01570:Myocd
|
APN |
11 |
65,091,633 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01865:Myocd
|
APN |
11 |
65,091,723 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL01938:Myocd
|
APN |
11 |
65,077,914 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02324:Myocd
|
APN |
11 |
65,069,484 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02598:Myocd
|
APN |
11 |
65,074,296 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL02886:Myocd
|
APN |
11 |
65,069,569 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03008:Myocd
|
APN |
11 |
65,078,392 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03034:Myocd
|
APN |
11 |
65,109,511 (GRCm39) |
missense |
probably benign |
0.00 |
|
harvey
|
UTSW |
11 |
65,069,856 (GRCm39) |
splice site |
probably null |
|
|
irma
|
UTSW |
11 |
65,087,220 (GRCm39) |
missense |
probably benign |
0.02 |
|
myra
|
UTSW |
11 |
65,069,685 (GRCm39) |
missense |
probably benign |
0.10 |
|
Nate
|
UTSW |
11 |
65,123,914 (GRCm39) |
splice site |
probably null |
|
|
R0838_Myocd_053
|
UTSW |
11 |
65,069,758 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0078:Myocd
|
UTSW |
11 |
65,078,290 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R0097:Myocd
|
UTSW |
11 |
65,069,840 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R0097:Myocd
|
UTSW |
11 |
65,069,840 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R0234:Myocd
|
UTSW |
11 |
65,078,066 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0234:Myocd
|
UTSW |
11 |
65,078,066 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0453:Myocd
|
UTSW |
11 |
65,087,051 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0523:Myocd
|
UTSW |
11 |
65,071,728 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0838:Myocd
|
UTSW |
11 |
65,069,758 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0899:Myocd
|
UTSW |
11 |
65,086,018 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1167:Myocd
|
UTSW |
11 |
65,087,203 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R1472:Myocd
|
UTSW |
11 |
65,078,330 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1508:Myocd
|
UTSW |
11 |
65,075,342 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1620:Myocd
|
UTSW |
11 |
65,087,220 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1630:Myocd
|
UTSW |
11 |
65,087,220 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1731:Myocd
|
UTSW |
11 |
65,091,714 (GRCm39) |
missense |
probably benign |
0.30 |
|
R1740:Myocd
|
UTSW |
11 |
65,109,347 (GRCm39) |
splice site |
probably benign |
|
|
R1769:Myocd
|
UTSW |
11 |
65,069,527 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1968:Myocd
|
UTSW |
11 |
65,091,733 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1997:Myocd
|
UTSW |
11 |
65,095,147 (GRCm39) |
nonsense |
probably null |
|
|
R2018:Myocd
|
UTSW |
11 |
65,077,854 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2105:Myocd
|
UTSW |
11 |
65,109,484 (GRCm39) |
nonsense |
probably null |
|
|
R2314:Myocd
|
UTSW |
11 |
65,091,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4330:Myocd
|
UTSW |
11 |
65,114,590 (GRCm39) |
missense |
probably benign |
0.12 |
|
R4331:Myocd
|
UTSW |
11 |
65,114,590 (GRCm39) |
missense |
probably benign |
0.12 |
|
R4603:Myocd
|
UTSW |
11 |
65,078,571 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4619:Myocd
|
UTSW |
11 |
65,069,254 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R4631:Myocd
|
UTSW |
11 |
65,069,685 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4865:Myocd
|
UTSW |
11 |
65,069,856 (GRCm39) |
splice site |
probably null |
|
|
R4974:Myocd
|
UTSW |
11 |
65,074,299 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R4976:Myocd
|
UTSW |
11 |
65,112,876 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5478:Myocd
|
UTSW |
11 |
65,123,914 (GRCm39) |
splice site |
probably null |
|
|
R5499:Myocd
|
UTSW |
11 |
65,069,575 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R6052:Myocd
|
UTSW |
11 |
65,087,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6356:Myocd
|
UTSW |
11 |
65,109,396 (GRCm39) |
splice site |
probably null |
|
|
R7144:Myocd
|
UTSW |
11 |
65,109,474 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7261:Myocd
|
UTSW |
11 |
65,078,422 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7354:Myocd
|
UTSW |
11 |
65,078,319 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7461:Myocd
|
UTSW |
11 |
65,109,429 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7613:Myocd
|
UTSW |
11 |
65,109,429 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7718:Myocd
|
UTSW |
11 |
65,109,452 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7956:Myocd
|
UTSW |
11 |
65,160,494 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8345:Myocd
|
UTSW |
11 |
65,077,958 (GRCm39) |
nonsense |
probably null |
|
|
R8975:Myocd
|
UTSW |
11 |
65,069,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9051:Myocd
|
UTSW |
11 |
65,077,795 (GRCm39) |
missense |
probably benign |
|
|
R9400:Myocd
|
UTSW |
11 |
65,086,934 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9469:Myocd
|
UTSW |
11 |
65,087,220 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9565:Myocd
|
UTSW |
11 |
65,078,209 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9567:Myocd
|
UTSW |
11 |
65,078,410 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9585:Myocd
|
UTSW |
11 |
65,095,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9710:Myocd
|
UTSW |
11 |
65,087,167 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9768:Myocd
|
UTSW |
11 |
65,078,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0057:Myocd
|
UTSW |
11 |
65,074,271 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
Z1186:Myocd
|
UTSW |
11 |
65,075,418 (GRCm39) |
missense |
probably benign |
|
|
Z1187:Myocd
|
UTSW |
11 |
65,075,418 (GRCm39) |
missense |
probably benign |
|
|
Z1188:Myocd
|
UTSW |
11 |
65,075,418 (GRCm39) |
missense |
probably benign |
|
|
Z1189:Myocd
|
UTSW |
11 |
65,075,418 (GRCm39) |
missense |
probably benign |
|
|
Z1190:Myocd
|
UTSW |
11 |
65,075,418 (GRCm39) |
missense |
probably benign |
|
|
Z1191:Myocd
|
UTSW |
11 |
65,075,418 (GRCm39) |
missense |
probably benign |
|
|
Z1192:Myocd
|
UTSW |
11 |
65,075,418 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TAGCTCTTGTACCTCGGGTG -3'
(R):5'- TGACGAACACCTGGAAGTC -3'
Sequencing Primer
(F):5'- CACTGCTGTAAGTGGAGATCC -3'
(R):5'- GACGAACACCTGGAAGTCTTATTG -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation