Incidental Mutation 'R1830:Shprh'
| ID |
207245 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Shprh
|
| Ensembl Gene |
ENSMUSG00000090112 |
| Gene Name |
SNF2 histone linker PHD RING helicase |
| Synonyms |
2610103K11Rik, D230017O13Rik |
| MMRRC Submission |
039857-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1830 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
10 |
| Chromosomal Location |
11025171-11093339 bp(+) (GRCm39) |
| Type of Mutation |
splice site (6 bp from exon) |
| DNA Base Change (assembly) |
T to C
at 11062655 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000132870
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000044053]
[ENSMUST00000054814]
[ENSMUST00000054814]
[ENSMUST00000159541]
[ENSMUST00000159541]
[ENSMUST00000159810]
|
| AlphaFold |
Q7TPQ3 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000044053
|
| SMART Domains |
Protein: ENSMUSP00000039422
Gene: ENSMUSG00000090112
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
3e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
low complexity region
|
1393 |
1404 |
N/A |
INTRINSIC |
|
RING
|
1423 |
1469 |
9.68e-3 |
SMART |
|
Pfam:Helicase_C
|
1500 |
1613 |
1.6e-8 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000054814
|
| SMART Domains |
Protein: ENSMUSP00000125849
Gene: ENSMUSG00000090112
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
3e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
low complexity region
|
1393 |
1404 |
N/A |
INTRINSIC |
|
RING
|
1423 |
1469 |
9.68e-3 |
SMART |
|
SCOP:d1fuka_
|
1504 |
1616 |
6e-8 |
SMART |
|
Blast:HELICc
|
1533 |
1613 |
4e-46 |
BLAST |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000054814
|
| SMART Domains |
Protein: ENSMUSP00000125849
Gene: ENSMUSG00000090112
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
3e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
low complexity region
|
1393 |
1404 |
N/A |
INTRINSIC |
|
RING
|
1423 |
1469 |
9.68e-3 |
SMART |
|
SCOP:d1fuka_
|
1504 |
1616 |
6e-8 |
SMART |
|
Blast:HELICc
|
1533 |
1613 |
4e-46 |
BLAST |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000159541
|
| SMART Domains |
Protein: ENSMUSP00000132870
Gene: ENSMUSG00000090112
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
3e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
low complexity region
|
1393 |
1404 |
N/A |
INTRINSIC |
|
RING
|
1423 |
1469 |
9.68e-3 |
SMART |
|
SCOP:d1fuka_
|
1504 |
1619 |
4e-8 |
SMART |
|
Blast:HELICc
|
1533 |
1613 |
6e-46 |
BLAST |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000159541
|
| SMART Domains |
Protein: ENSMUSP00000132870
Gene: ENSMUSG00000090112
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
3e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
low complexity region
|
1393 |
1404 |
N/A |
INTRINSIC |
|
RING
|
1423 |
1469 |
9.68e-3 |
SMART |
|
SCOP:d1fuka_
|
1504 |
1619 |
4e-8 |
SMART |
|
Blast:HELICc
|
1533 |
1613 |
6e-46 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000159553
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000159810
|
| SMART Domains |
Protein: ENSMUSP00000125457
Gene: ENSMUSG00000090112
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
2e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
Blast:DEXDc
|
948 |
1026 |
2e-9 |
BLAST |
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.2%
- 20x: 92.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] SHPRH is a ubiquitously expressed protein that contains motifs characteristics of several DNA repair proteins, transcription factors, and helicases. SHPRH is a functional homolog of S. cerevisiae RAD5 (Unk et al., 2006 [PubMed 17108083]).[supplied by OMIM, Mar 2008]
PHENOTYPE: The gene product is an E3 ligase involved in poly-ubiquitination of Pcna. Neither homozygous truncation nor KO affect B cell somatic hypermutation or class switching. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca13 |
T |
C |
11: 9,240,350 (GRCm39) |
S738P |
probably benign |
Het |
| Abi3bp |
C |
A |
16: 56,408,348 (GRCm39) |
P261Q |
probably damaging |
Het |
| Adam19 |
A |
G |
11: 46,018,105 (GRCm39) |
N389S |
probably damaging |
Het |
| Adgrv1 |
A |
T |
13: 81,637,196 (GRCm39) |
V3415D |
possibly damaging |
Het |
| Ankrd33 |
A |
T |
15: 101,017,432 (GRCm39) |
I282F |
probably damaging |
Het |
| Arhgap39 |
C |
T |
15: 76,619,383 (GRCm39) |
V734M |
probably damaging |
Het |
| Arsg |
T |
C |
11: 109,454,100 (GRCm39) |
|
probably null |
Het |
| Atp8b4 |
C |
T |
2: 126,245,301 (GRCm39) |
G283R |
probably benign |
Het |
| B3galnt2 |
T |
G |
13: 14,166,119 (GRCm39) |
L338* |
probably null |
Het |
| Cdc14a |
A |
T |
3: 116,216,296 (GRCm39) |
Y1* |
probably null |
Het |
| Ceacam16 |
T |
C |
7: 19,592,803 (GRCm39) |
E35G |
possibly damaging |
Het |
| Cfap46 |
T |
A |
7: 139,220,323 (GRCm39) |
D1244V |
possibly damaging |
Het |
| Chordc1 |
T |
C |
9: 18,223,274 (GRCm39) |
Y245H |
probably damaging |
Het |
| Col6a6 |
C |
A |
9: 105,579,469 (GRCm39) |
V1919F |
probably damaging |
Het |
| Colgalt1 |
T |
C |
8: 72,075,781 (GRCm39) |
V476A |
probably damaging |
Het |
| Cped1 |
T |
C |
6: 22,237,727 (GRCm39) |
C948R |
probably damaging |
Het |
| Cyfip2 |
T |
C |
11: 46,089,846 (GRCm39) |
D1189G |
probably damaging |
Het |
| Cyp27b1 |
T |
C |
10: 126,884,952 (GRCm39) |
Y72H |
possibly damaging |
Het |
| Dagla |
A |
G |
19: 10,248,378 (GRCm39) |
M94T |
probably benign |
Het |
| Dip2a |
A |
G |
10: 76,153,797 (GRCm39) |
S178P |
probably damaging |
Het |
| Dlec1 |
T |
C |
9: 118,967,858 (GRCm39) |
V1220A |
probably benign |
Het |
| Dpysl2 |
T |
C |
14: 67,105,840 (GRCm39) |
|
probably benign |
Het |
| E2f6 |
T |
C |
12: 16,868,884 (GRCm39) |
V69A |
probably benign |
Het |
| Fat3 |
T |
C |
9: 15,826,636 (GRCm39) |
T4439A |
probably benign |
Het |
| Fn1 |
T |
C |
1: 71,663,418 (GRCm39) |
I1023M |
probably damaging |
Het |
| Gabrr2 |
G |
A |
4: 33,077,481 (GRCm39) |
V83M |
probably damaging |
Het |
| Gfral |
T |
C |
9: 76,100,485 (GRCm39) |
N318D |
probably benign |
Het |
| Gm5611 |
A |
T |
9: 16,942,073 (GRCm39) |
|
noncoding transcript |
Het |
| Gpat3 |
A |
T |
5: 101,041,046 (GRCm39) |
M369L |
probably benign |
Het |
| Grik5 |
T |
C |
7: 24,745,726 (GRCm39) |
D449G |
possibly damaging |
Het |
| Gucy2g |
T |
A |
19: 55,211,362 (GRCm39) |
T623S |
possibly damaging |
Het |
| H2-T22 |
T |
C |
17: 36,352,434 (GRCm39) |
T164A |
probably benign |
Het |
| Herc1 |
T |
A |
9: 66,404,881 (GRCm39) |
C4484S |
possibly damaging |
Het |
| Hira |
T |
C |
16: 18,766,164 (GRCm39) |
S659P |
probably damaging |
Het |
| Hoxa7 |
T |
C |
6: 52,194,307 (GRCm39) |
T27A |
possibly damaging |
Het |
| Hoxd1 |
T |
C |
2: 74,593,866 (GRCm39) |
S141P |
probably damaging |
Het |
| Kank1 |
C |
A |
19: 25,388,396 (GRCm39) |
Q690K |
probably benign |
Het |
| Kera |
A |
G |
10: 97,445,009 (GRCm39) |
K123E |
probably benign |
Het |
| Kifbp |
T |
C |
10: 62,395,106 (GRCm39) |
Y512C |
probably damaging |
Het |
| Lepr |
A |
C |
4: 101,592,874 (GRCm39) |
Y163S |
probably damaging |
Het |
| Leprotl1 |
T |
C |
8: 34,607,922 (GRCm39) |
I29V |
probably benign |
Het |
| Lrriq1 |
T |
G |
10: 102,997,620 (GRCm39) |
T1332P |
probably benign |
Het |
| Mrps15 |
A |
G |
4: 125,949,200 (GRCm39) |
K223E |
probably damaging |
Het |
| Mrps7 |
T |
A |
11: 115,497,811 (GRCm39) |
N225K |
probably benign |
Het |
| Nav3 |
T |
A |
10: 109,659,184 (GRCm39) |
D811V |
probably damaging |
Het |
| Ndst3 |
T |
A |
3: 123,342,587 (GRCm39) |
R741S |
probably damaging |
Het |
| Nos3 |
T |
C |
5: 24,575,131 (GRCm39) |
Y356H |
probably damaging |
Het |
| Nxpe3 |
A |
G |
16: 55,686,444 (GRCm39) |
V188A |
probably damaging |
Het |
| Or13n4 |
T |
C |
7: 106,423,317 (GRCm39) |
R139G |
probably benign |
Het |
| Or5p50 |
T |
A |
7: 107,422,578 (GRCm39) |
I33F |
probably benign |
Het |
| Or8j3b |
T |
C |
2: 86,205,487 (GRCm39) |
K90E |
possibly damaging |
Het |
| Pdia4 |
A |
T |
6: 47,773,695 (GRCm39) |
C551* |
probably null |
Het |
| Pex13 |
A |
G |
11: 23,605,513 (GRCm39) |
F239S |
probably damaging |
Het |
| Pigq |
A |
G |
17: 26,153,980 (GRCm39) |
M273T |
probably benign |
Het |
| Plppr2 |
C |
T |
9: 21,859,047 (GRCm39) |
P388L |
probably damaging |
Het |
| Polr3b |
C |
T |
10: 84,528,786 (GRCm39) |
Q737* |
probably null |
Het |
| Ppfibp1 |
T |
C |
6: 146,923,757 (GRCm39) |
|
probably null |
Het |
| Ppfibp2 |
C |
A |
7: 107,236,504 (GRCm39) |
D17E |
probably damaging |
Het |
| Pramel34 |
A |
T |
5: 93,785,545 (GRCm39) |
I245K |
probably benign |
Het |
| Prr35 |
T |
C |
17: 26,165,691 (GRCm39) |
D532G |
possibly damaging |
Het |
| Ptpn13 |
A |
G |
5: 103,691,325 (GRCm39) |
D1064G |
probably benign |
Het |
| Qtrt2 |
A |
T |
16: 43,692,018 (GRCm39) |
S168T |
probably damaging |
Het |
| Rbp3 |
T |
C |
14: 33,676,601 (GRCm39) |
V183A |
probably benign |
Het |
| Slc39a10 |
T |
C |
1: 46,875,230 (GRCm39) |
H24R |
probably damaging |
Het |
| Slc7a13 |
A |
T |
4: 19,819,046 (GRCm39) |
H82L |
probably benign |
Het |
| Sptbn2 |
A |
G |
19: 4,782,569 (GRCm39) |
I502V |
probably benign |
Het |
| Syne2 |
C |
T |
12: 76,156,636 (GRCm39) |
R6811C |
probably damaging |
Het |
| Syt12 |
A |
G |
19: 4,506,911 (GRCm39) |
V78A |
probably benign |
Het |
| Tbck |
T |
A |
3: 132,543,772 (GRCm39) |
D874E |
probably benign |
Het |
| Tesc |
A |
T |
5: 118,184,394 (GRCm39) |
I25L |
probably damaging |
Het |
| Thoc5 |
T |
G |
11: 4,864,608 (GRCm39) |
D351E |
probably benign |
Het |
| Tor1aip1 |
A |
T |
1: 155,883,308 (GRCm39) |
M180K |
probably damaging |
Het |
| Trps1 |
T |
C |
15: 50,524,532 (GRCm39) |
S842G |
probably damaging |
Het |
| Unc79 |
A |
T |
12: 103,100,737 (GRCm39) |
T1858S |
probably damaging |
Het |
| Vmn1r193 |
T |
C |
13: 22,403,561 (GRCm39) |
T144A |
probably benign |
Het |
| Vwa8 |
T |
C |
14: 79,318,576 (GRCm39) |
F1046S |
probably benign |
Het |
| Wdr26 |
A |
T |
1: 181,019,340 (GRCm39) |
W346R |
probably damaging |
Het |
| Zfp740 |
T |
A |
15: 102,116,336 (GRCm39) |
V22E |
probably damaging |
Het |
| Zw10 |
C |
A |
9: 48,981,041 (GRCm39) |
S480R |
probably damaging |
Het |
|
| Other mutations in Shprh |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00492:Shprh
|
APN |
10 |
11,063,902 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00583:Shprh
|
APN |
10 |
11,063,764 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL00684:Shprh
|
APN |
10 |
11,038,781 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL01295:Shprh
|
APN |
10 |
11,059,612 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01387:Shprh
|
APN |
10 |
11,045,998 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01635:Shprh
|
APN |
10 |
11,045,763 (GRCm39) |
nonsense |
probably null |
|
|
IGL01833:Shprh
|
APN |
10 |
11,066,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02013:Shprh
|
APN |
10 |
11,057,246 (GRCm39) |
splice site |
probably benign |
|
|
IGL02502:Shprh
|
APN |
10 |
11,070,101 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
IGL02819:Shprh
|
APN |
10 |
11,030,509 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
PIT4581001:Shprh
|
UTSW |
10 |
11,068,238 (GRCm39) |
frame shift |
probably null |
|
|
R0010:Shprh
|
UTSW |
10 |
11,027,675 (GRCm39) |
missense |
probably benign |
|
|
R0010:Shprh
|
UTSW |
10 |
11,027,675 (GRCm39) |
missense |
probably benign |
|
|
R0053:Shprh
|
UTSW |
10 |
11,070,116 (GRCm39) |
splice site |
probably null |
|
|
R0053:Shprh
|
UTSW |
10 |
11,070,116 (GRCm39) |
splice site |
probably null |
|
|
R0255:Shprh
|
UTSW |
10 |
11,062,135 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0325:Shprh
|
UTSW |
10 |
11,045,853 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0331:Shprh
|
UTSW |
10 |
11,069,914 (GRCm39) |
splice site |
probably benign |
|
|
R0494:Shprh
|
UTSW |
10 |
11,032,935 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0532:Shprh
|
UTSW |
10 |
11,038,556 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0546:Shprh
|
UTSW |
10 |
11,059,631 (GRCm39) |
splice site |
probably benign |
|
|
R0574:Shprh
|
UTSW |
10 |
11,038,821 (GRCm39) |
unclassified |
probably benign |
|
|
R0605:Shprh
|
UTSW |
10 |
11,082,856 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0662:Shprh
|
UTSW |
10 |
11,062,591 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1148:Shprh
|
UTSW |
10 |
11,089,226 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1148:Shprh
|
UTSW |
10 |
11,089,226 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1263:Shprh
|
UTSW |
10 |
11,035,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1588:Shprh
|
UTSW |
10 |
11,040,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1638:Shprh
|
UTSW |
10 |
11,032,822 (GRCm39) |
missense |
probably benign |
|
|
R1898:Shprh
|
UTSW |
10 |
11,062,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1903:Shprh
|
UTSW |
10 |
11,059,541 (GRCm39) |
nonsense |
probably null |
|
|
R2060:Shprh
|
UTSW |
10 |
11,027,864 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2225:Shprh
|
UTSW |
10 |
11,037,979 (GRCm39) |
unclassified |
probably benign |
|
|
R2363:Shprh
|
UTSW |
10 |
11,047,697 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2509:Shprh
|
UTSW |
10 |
11,042,468 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2891:Shprh
|
UTSW |
10 |
11,040,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3077:Shprh
|
UTSW |
10 |
11,046,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3150:Shprh
|
UTSW |
10 |
11,045,774 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3796:Shprh
|
UTSW |
10 |
11,054,501 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4196:Shprh
|
UTSW |
10 |
11,083,604 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R4423:Shprh
|
UTSW |
10 |
11,062,262 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4488:Shprh
|
UTSW |
10 |
11,036,215 (GRCm39) |
missense |
probably benign |
0.17 |
|
R4748:Shprh
|
UTSW |
10 |
11,046,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4768:Shprh
|
UTSW |
10 |
11,057,284 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4867:Shprh
|
UTSW |
10 |
11,040,301 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4937:Shprh
|
UTSW |
10 |
11,032,863 (GRCm39) |
missense |
probably benign |
|
|
R5140:Shprh
|
UTSW |
10 |
11,030,449 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5318:Shprh
|
UTSW |
10 |
11,042,301 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5323:Shprh
|
UTSW |
10 |
11,046,041 (GRCm39) |
splice site |
probably null |
|
|
R5450:Shprh
|
UTSW |
10 |
11,088,074 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R5872:Shprh
|
UTSW |
10 |
11,063,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6030:Shprh
|
UTSW |
10 |
11,027,735 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6030:Shprh
|
UTSW |
10 |
11,027,735 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6392:Shprh
|
UTSW |
10 |
11,054,485 (GRCm39) |
nonsense |
probably null |
|
|
R6416:Shprh
|
UTSW |
10 |
11,043,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6470:Shprh
|
UTSW |
10 |
11,047,681 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6513:Shprh
|
UTSW |
10 |
11,062,637 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6530:Shprh
|
UTSW |
10 |
11,070,011 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6678:Shprh
|
UTSW |
10 |
11,042,289 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6757:Shprh
|
UTSW |
10 |
11,057,252 (GRCm39) |
splice site |
probably null |
|
|
R6971:Shprh
|
UTSW |
10 |
11,042,437 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7158:Shprh
|
UTSW |
10 |
11,042,474 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7582:Shprh
|
UTSW |
10 |
11,040,449 (GRCm39) |
missense |
probably benign |
|
|
R7757:Shprh
|
UTSW |
10 |
11,037,924 (GRCm39) |
missense |
probably benign |
0.30 |
|
R7812:Shprh
|
UTSW |
10 |
11,027,735 (GRCm39) |
missense |
probably benign |
|
|
R7998:Shprh
|
UTSW |
10 |
11,061,085 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8061:Shprh
|
UTSW |
10 |
11,088,077 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8082:Shprh
|
UTSW |
10 |
11,027,555 (GRCm39) |
missense |
probably benign |
0.22 |
|
R8116:Shprh
|
UTSW |
10 |
11,089,205 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8390:Shprh
|
UTSW |
10 |
11,063,727 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8445:Shprh
|
UTSW |
10 |
11,057,313 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8530:Shprh
|
UTSW |
10 |
11,027,678 (GRCm39) |
missense |
probably benign |
0.37 |
|
R8759:Shprh
|
UTSW |
10 |
11,032,908 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8937:Shprh
|
UTSW |
10 |
11,061,181 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R8995:Shprh
|
UTSW |
10 |
11,040,574 (GRCm39) |
nonsense |
probably null |
|
|
R9053:Shprh
|
UTSW |
10 |
11,030,446 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9131:Shprh
|
UTSW |
10 |
11,038,589 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R9176:Shprh
|
UTSW |
10 |
11,036,320 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9391:Shprh
|
UTSW |
10 |
11,038,633 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9423:Shprh
|
UTSW |
10 |
11,081,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9563:Shprh
|
UTSW |
10 |
11,042,235 (GRCm39) |
nonsense |
probably null |
|
|
R9668:Shprh
|
UTSW |
10 |
11,082,076 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9709:Shprh
|
UTSW |
10 |
11,038,574 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9718:Shprh
|
UTSW |
10 |
11,089,248 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9750:Shprh
|
UTSW |
10 |
11,040,204 (GRCm39) |
missense |
probably damaging |
0.98 |
|
RF012:Shprh
|
UTSW |
10 |
11,040,585 (GRCm39) |
missense |
probably benign |
0.02 |
|
V8831:Shprh
|
UTSW |
10 |
11,062,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Shprh
|
UTSW |
10 |
11,062,191 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Shprh
|
UTSW |
10 |
11,040,297 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Shprh
|
UTSW |
10 |
11,027,506 (GRCm39) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GGATCATGTGCTTGAAAACCATTTC -3'
(R):5'- ACATTTAGGTGTAGCTTCTATGGAG -3'
Sequencing Primer
(F):5'- CAAAATGCTGGGGATTTTTG -3'
(R):5'- GGCATGTTAAATCCCAAAGG -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation