Incidental Mutation 'R0116:Myom2'
| ID |
20802 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myom2
|
| Ensembl Gene |
ENSMUSG00000031461 |
| Gene Name |
myomesin 2 |
| Synonyms |
|
| MMRRC Submission |
038402-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.149)
|
| Stock # |
R0116 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
8 |
| Chromosomal Location |
15107653-15183410 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 15167633 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Phenylalanine
at position 1073
(I1073F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000033842
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000033842]
|
| AlphaFold |
Q14BI5 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000033842
AA Change: I1073F
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000033842
Gene: ENSMUSG00000031461
AA Change: I1073F
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
34 |
63 |
N/A |
INTRINSIC |
|
low complexity region
|
79 |
87 |
N/A |
INTRINSIC |
|
coiled coil region
|
97 |
129 |
N/A |
INTRINSIC |
|
IG
|
160 |
247 |
7.7e-5 |
SMART |
|
IG
|
284 |
373 |
8.01e-3 |
SMART |
|
FN3
|
383 |
466 |
1.5e-14 |
SMART |
|
FN3
|
511 |
594 |
1.79e-12 |
SMART |
|
FN3
|
612 |
693 |
1.95e-13 |
SMART |
|
FN3
|
711 |
794 |
8.69e-11 |
SMART |
|
FN3
|
813 |
896 |
1.86e-10 |
SMART |
|
IG_like
|
913 |
999 |
1.58e2 |
SMART |
|
Blast:IG_like
|
1021 |
1106 |
1e-44 |
BLAST |
|
IG_like
|
1135 |
1215 |
2.27e1 |
SMART |
|
Blast:IG_like
|
1227 |
1321 |
9e-51 |
BLAST |
|
IGc2
|
1357 |
1425 |
4.96e-8 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000140033
|
| Meta Mutation Damage Score |
0.3312 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.7%
- 20x: 94.2%
|
| Validation Efficiency |
94% (95/101) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 95 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4931406C07Rik |
A |
T |
9: 15,202,066 (GRCm39) |
V152E |
probably damaging |
Het |
| Abca5 |
T |
G |
11: 110,167,331 (GRCm39) |
E1495A |
probably damaging |
Het |
| Abcc12 |
G |
A |
8: 87,261,627 (GRCm39) |
S668F |
probably benign |
Het |
| Adgrl4 |
A |
T |
3: 151,223,247 (GRCm39) |
T608S |
probably benign |
Het |
| Angel2 |
G |
A |
1: 190,673,187 (GRCm39) |
D255N |
probably benign |
Het |
| Apob |
T |
A |
12: 8,039,113 (GRCm39) |
|
probably benign |
Het |
| Arfgef2 |
A |
T |
2: 166,715,603 (GRCm39) |
R1349S |
probably damaging |
Het |
| Atp2b2 |
C |
T |
6: 113,770,656 (GRCm39) |
V418I |
probably damaging |
Het |
| Birc6 |
C |
A |
17: 74,930,741 (GRCm39) |
|
probably benign |
Het |
| Capn13 |
T |
A |
17: 73,658,519 (GRCm39) |
Y183F |
probably damaging |
Het |
| Cngb1 |
A |
G |
8: 95,987,266 (GRCm39) |
S352P |
probably damaging |
Het |
| Col6a3 |
A |
G |
1: 90,741,273 (GRCm39) |
S720P |
probably damaging |
Het |
| Cpa4 |
C |
T |
6: 30,579,657 (GRCm39) |
R155W |
probably damaging |
Het |
| Dapk1 |
A |
G |
13: 60,908,914 (GRCm39) |
I1176V |
probably benign |
Het |
| Dnah17 |
T |
C |
11: 117,949,132 (GRCm39) |
E2959G |
probably benign |
Het |
| Dnah7b |
T |
A |
1: 46,252,520 (GRCm39) |
I1734N |
possibly damaging |
Het |
| Dnajb7 |
A |
G |
15: 81,291,555 (GRCm39) |
Y261H |
probably benign |
Het |
| Dock2 |
T |
C |
11: 34,579,392 (GRCm39) |
|
probably benign |
Het |
| Dyrk3 |
A |
T |
1: 131,057,576 (GRCm39) |
V199E |
probably damaging |
Het |
| F2r |
G |
T |
13: 95,740,994 (GRCm39) |
C180* |
probably null |
Het |
| F5 |
A |
G |
1: 164,012,483 (GRCm39) |
S466G |
probably benign |
Het |
| Fbn2 |
A |
T |
18: 58,235,445 (GRCm39) |
C677* |
probably null |
Het |
| Fbxo41 |
A |
G |
6: 85,454,890 (GRCm39) |
S673P |
probably damaging |
Het |
| Fhad1 |
G |
T |
4: 141,667,406 (GRCm39) |
H639N |
probably benign |
Het |
| Fmnl3 |
G |
C |
15: 99,220,619 (GRCm39) |
|
probably benign |
Het |
| Foxa2 |
A |
G |
2: 147,885,481 (GRCm39) |
S270P |
probably damaging |
Het |
| Fxyd7 |
C |
T |
7: 30,746,793 (GRCm39) |
|
probably null |
Het |
| Gm5225 |
A |
G |
17: 24,243,032 (GRCm39) |
D67G |
probably benign |
Het |
| Grik3 |
G |
A |
4: 125,564,349 (GRCm39) |
E444K |
probably benign |
Het |
| Gsdma2 |
A |
G |
11: 98,540,009 (GRCm39) |
K44E |
probably damaging |
Het |
| Haus1 |
T |
A |
18: 77,849,770 (GRCm39) |
K130* |
probably null |
Het |
| Heg1 |
A |
G |
16: 33,556,028 (GRCm39) |
|
probably benign |
Het |
| Hormad2 |
A |
G |
11: 4,362,206 (GRCm39) |
|
probably benign |
Het |
| Hsd17b3 |
G |
A |
13: 64,206,403 (GRCm39) |
R300C |
possibly damaging |
Het |
| Irf5 |
T |
C |
6: 29,536,108 (GRCm39) |
F374S |
probably damaging |
Het |
| Itch |
A |
G |
2: 155,059,903 (GRCm39) |
|
probably benign |
Het |
| Jade2 |
A |
T |
11: 51,722,136 (GRCm39) |
L139Q |
probably damaging |
Het |
| Kif5c |
G |
A |
2: 49,642,251 (GRCm39) |
|
probably benign |
Het |
| Lama1 |
T |
C |
17: 68,083,918 (GRCm39) |
Y1387H |
probably benign |
Het |
| Larp4b |
A |
G |
13: 9,220,724 (GRCm39) |
R658G |
probably damaging |
Het |
| Mcph1 |
C |
T |
8: 18,838,264 (GRCm39) |
L729F |
probably benign |
Het |
| Me1 |
A |
T |
9: 86,536,720 (GRCm39) |
N118K |
probably benign |
Het |
| Med13 |
A |
G |
11: 86,210,723 (GRCm39) |
L473S |
probably damaging |
Het |
| Mgam |
T |
A |
6: 40,635,921 (GRCm39) |
Y359N |
probably damaging |
Het |
| Morc2b |
A |
G |
17: 33,356,015 (GRCm39) |
S586P |
probably damaging |
Het |
| Mthfr |
A |
G |
4: 148,135,980 (GRCm39) |
D310G |
probably benign |
Het |
| Mtmr7 |
A |
T |
8: 41,034,447 (GRCm39) |
|
probably benign |
Het |
| Mtus1 |
A |
G |
8: 41,451,514 (GRCm39) |
|
probably benign |
Het |
| Mus81 |
G |
T |
19: 5,536,552 (GRCm39) |
A138D |
probably damaging |
Het |
| Nhsl1 |
A |
T |
10: 18,400,990 (GRCm39) |
K739* |
probably null |
Het |
| Nlrp4d |
T |
A |
7: 10,108,818 (GRCm39) |
K762N |
probably benign |
Het |
| Nrap |
T |
C |
19: 56,343,978 (GRCm39) |
Y724C |
probably damaging |
Het |
| Ogn |
A |
T |
13: 49,774,514 (GRCm39) |
Y219F |
possibly damaging |
Het |
| Or6c212 |
T |
A |
10: 129,558,846 (GRCm39) |
D189V |
probably damaging |
Het |
| Or8b56 |
T |
C |
9: 38,739,860 (GRCm39) |
L291P |
probably damaging |
Het |
| Or8g30 |
A |
T |
9: 39,230,160 (GRCm39) |
I250N |
probably damaging |
Het |
| Padi2 |
T |
C |
4: 140,653,550 (GRCm39) |
V180A |
probably benign |
Het |
| Papss2 |
C |
T |
19: 32,615,768 (GRCm39) |
R167* |
probably null |
Het |
| Pcbp2 |
T |
C |
15: 102,382,670 (GRCm39) |
|
probably benign |
Het |
| Per1 |
T |
A |
11: 68,992,706 (GRCm39) |
|
probably benign |
Het |
| Pik3ca |
T |
C |
3: 32,514,094 (GRCm39) |
I860T |
probably damaging |
Het |
| Pkdrej |
G |
A |
15: 85,701,746 (GRCm39) |
Q1397* |
probably null |
Het |
| Plce1 |
T |
C |
19: 38,710,265 (GRCm39) |
V1133A |
probably benign |
Het |
| Pnma8a |
T |
G |
7: 16,694,625 (GRCm39) |
V160G |
probably damaging |
Het |
| Prss12 |
T |
C |
3: 123,276,423 (GRCm39) |
C351R |
probably damaging |
Het |
| Qprt |
A |
T |
7: 126,708,269 (GRCm39) |
L54Q |
probably damaging |
Het |
| Raf1 |
C |
T |
6: 115,603,344 (GRCm39) |
S165N |
probably damaging |
Het |
| Rere |
A |
G |
4: 150,701,433 (GRCm39) |
N1271S |
probably benign |
Het |
| Rnasel |
T |
A |
1: 153,630,258 (GRCm39) |
L258H |
probably damaging |
Het |
| Ryr2 |
T |
C |
13: 11,724,807 (GRCm39) |
D2502G |
probably damaging |
Het |
| Ryr3 |
G |
A |
2: 112,633,510 (GRCm39) |
S2081L |
probably damaging |
Het |
| Sc5d |
G |
T |
9: 42,171,155 (GRCm39) |
Y11* |
probably null |
Het |
| Slc25a29 |
A |
C |
12: 108,793,017 (GRCm39) |
L187R |
possibly damaging |
Het |
| Slc2a7 |
G |
A |
4: 150,252,721 (GRCm39) |
V454M |
probably benign |
Het |
| Slco1b2 |
A |
T |
6: 141,615,114 (GRCm39) |
T340S |
probably benign |
Het |
| Smarcc1 |
A |
G |
9: 109,976,172 (GRCm39) |
N153S |
possibly damaging |
Het |
| Snx1 |
C |
A |
9: 65,995,821 (GRCm39) |
E516* |
probably null |
Het |
| Sptlc2 |
T |
C |
12: 87,403,454 (GRCm39) |
D115G |
probably benign |
Het |
| Stard9 |
A |
G |
2: 120,464,736 (GRCm39) |
N67S |
probably damaging |
Het |
| Styxl2 |
A |
C |
1: 165,927,270 (GRCm39) |
S781A |
probably benign |
Het |
| Swap70 |
G |
A |
7: 109,872,489 (GRCm39) |
R368H |
probably benign |
Het |
| Tcaf3 |
T |
C |
6: 42,568,284 (GRCm39) |
K691E |
probably benign |
Het |
| Tmco4 |
T |
C |
4: 138,781,231 (GRCm39) |
F465S |
probably damaging |
Het |
| Tmem245 |
A |
G |
4: 56,926,213 (GRCm39) |
S290P |
probably benign |
Het |
| Top2a |
T |
C |
11: 98,894,416 (GRCm39) |
T972A |
probably benign |
Het |
| Tpr |
T |
A |
1: 150,285,898 (GRCm39) |
S527R |
probably damaging |
Het |
| Traf2 |
T |
C |
2: 25,409,621 (GRCm39) |
D443G |
probably damaging |
Het |
| Trim40 |
A |
T |
17: 37,194,039 (GRCm39) |
|
probably null |
Het |
| Trim42 |
A |
T |
9: 97,245,456 (GRCm39) |
I448N |
possibly damaging |
Het |
| Ttll9 |
G |
A |
2: 152,825,054 (GRCm39) |
V78M |
probably damaging |
Het |
| Vav1 |
C |
T |
17: 57,603,039 (GRCm39) |
L88F |
probably damaging |
Het |
| Vps13b |
A |
G |
15: 35,423,301 (GRCm39) |
D207G |
probably damaging |
Het |
| Wdsub1 |
A |
G |
2: 59,707,009 (GRCm39) |
|
probably null |
Het |
| Zfp799 |
A |
G |
17: 33,040,009 (GRCm39) |
W85R |
possibly damaging |
Het |
| Zfp839 |
A |
T |
12: 110,825,203 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Myom2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00422:Myom2
|
APN |
8 |
15,119,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00426:Myom2
|
APN |
8 |
15,119,502 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00503:Myom2
|
APN |
8 |
15,164,289 (GRCm39) |
splice site |
probably null |
|
|
IGL01515:Myom2
|
APN |
8 |
15,172,655 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL01649:Myom2
|
APN |
8 |
15,163,755 (GRCm39) |
missense |
probably benign |
0.24 |
|
IGL01658:Myom2
|
APN |
8 |
15,127,880 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01786:Myom2
|
APN |
8 |
15,156,330 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01924:Myom2
|
APN |
8 |
15,119,685 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL01929:Myom2
|
APN |
8 |
15,167,698 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02016:Myom2
|
APN |
8 |
15,175,195 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02511:Myom2
|
APN |
8 |
15,115,743 (GRCm39) |
missense |
probably benign |
|
|
IGL02558:Myom2
|
APN |
8 |
15,164,237 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL02944:Myom2
|
APN |
8 |
15,154,065 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL03052:Myom2
|
APN |
8 |
15,173,442 (GRCm39) |
splice site |
probably benign |
|
|
IGL03195:Myom2
|
APN |
8 |
15,161,844 (GRCm39) |
nonsense |
probably null |
|
|
IGL03288:Myom2
|
APN |
8 |
15,172,679 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03402:Myom2
|
APN |
8 |
15,115,731 (GRCm39) |
missense |
probably benign |
|
|
yomama
|
UTSW |
8 |
15,182,895 (GRCm39) |
missense |
probably benign |
0.10 |
|
yoyoma
|
UTSW |
8 |
15,182,667 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0069:Myom2
|
UTSW |
8 |
15,167,624 (GRCm39) |
missense |
probably benign |
|
|
R0131:Myom2
|
UTSW |
8 |
15,133,329 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0373:Myom2
|
UTSW |
8 |
15,148,419 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0463:Myom2
|
UTSW |
8 |
15,154,123 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0544:Myom2
|
UTSW |
8 |
15,119,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0629:Myom2
|
UTSW |
8 |
15,119,783 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0634:Myom2
|
UTSW |
8 |
15,169,216 (GRCm39) |
splice site |
probably benign |
|
|
R0645:Myom2
|
UTSW |
8 |
15,167,698 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0730:Myom2
|
UTSW |
8 |
15,149,326 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0744:Myom2
|
UTSW |
8 |
15,182,924 (GRCm39) |
nonsense |
probably null |
|
|
R0836:Myom2
|
UTSW |
8 |
15,182,924 (GRCm39) |
nonsense |
probably null |
|
|
R1033:Myom2
|
UTSW |
8 |
15,158,934 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1103:Myom2
|
UTSW |
8 |
15,160,827 (GRCm39) |
missense |
probably benign |
0.22 |
|
R1110:Myom2
|
UTSW |
8 |
15,172,413 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1208:Myom2
|
UTSW |
8 |
15,134,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1208:Myom2
|
UTSW |
8 |
15,134,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1353:Myom2
|
UTSW |
8 |
15,156,424 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1530:Myom2
|
UTSW |
8 |
15,172,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1544:Myom2
|
UTSW |
8 |
15,154,059 (GRCm39) |
splice site |
probably benign |
|
|
R1576:Myom2
|
UTSW |
8 |
15,134,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1758:Myom2
|
UTSW |
8 |
15,115,795 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1884:Myom2
|
UTSW |
8 |
15,164,278 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1908:Myom2
|
UTSW |
8 |
15,131,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1962:Myom2
|
UTSW |
8 |
15,182,599 (GRCm39) |
splice site |
probably null |
|
|
R1977:Myom2
|
UTSW |
8 |
15,135,263 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R2018:Myom2
|
UTSW |
8 |
15,181,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2049:Myom2
|
UTSW |
8 |
15,156,379 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2155:Myom2
|
UTSW |
8 |
15,134,555 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2314:Myom2
|
UTSW |
8 |
15,113,927 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2350:Myom2
|
UTSW |
8 |
15,158,835 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2358:Myom2
|
UTSW |
8 |
15,162,018 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R2904:Myom2
|
UTSW |
8 |
15,148,348 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3418:Myom2
|
UTSW |
8 |
15,135,294 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3606:Myom2
|
UTSW |
8 |
15,119,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3607:Myom2
|
UTSW |
8 |
15,119,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3735:Myom2
|
UTSW |
8 |
15,119,676 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3756:Myom2
|
UTSW |
8 |
15,152,650 (GRCm39) |
missense |
probably benign |
0.11 |
|
R3902:Myom2
|
UTSW |
8 |
15,154,165 (GRCm39) |
missense |
probably benign |
|
|
R3951:Myom2
|
UTSW |
8 |
15,134,556 (GRCm39) |
missense |
probably benign |
0.35 |
|
R4240:Myom2
|
UTSW |
8 |
15,182,895 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4361:Myom2
|
UTSW |
8 |
15,162,018 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4581:Myom2
|
UTSW |
8 |
15,156,459 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4736:Myom2
|
UTSW |
8 |
15,131,271 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5010:Myom2
|
UTSW |
8 |
15,133,310 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5108:Myom2
|
UTSW |
8 |
15,182,667 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5370:Myom2
|
UTSW |
8 |
15,149,343 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5427:Myom2
|
UTSW |
8 |
15,163,764 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5498:Myom2
|
UTSW |
8 |
15,179,142 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5504:Myom2
|
UTSW |
8 |
15,178,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5567:Myom2
|
UTSW |
8 |
15,152,546 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5743:Myom2
|
UTSW |
8 |
15,130,914 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R5745:Myom2
|
UTSW |
8 |
15,172,705 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5844:Myom2
|
UTSW |
8 |
15,181,182 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5854:Myom2
|
UTSW |
8 |
15,158,478 (GRCm39) |
missense |
probably benign |
|
|
R6141:Myom2
|
UTSW |
8 |
15,113,903 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6209:Myom2
|
UTSW |
8 |
15,154,173 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R6248:Myom2
|
UTSW |
8 |
15,148,472 (GRCm39) |
splice site |
probably null |
|
|
R6378:Myom2
|
UTSW |
8 |
15,149,356 (GRCm39) |
missense |
probably benign |
0.11 |
|
R6829:Myom2
|
UTSW |
8 |
15,172,643 (GRCm39) |
nonsense |
probably null |
|
|
R6913:Myom2
|
UTSW |
8 |
15,115,710 (GRCm39) |
missense |
probably benign |
|
|
R6957:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6958:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6960:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6961:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6962:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6999:Myom2
|
UTSW |
8 |
15,134,531 (GRCm39) |
missense |
probably benign |
0.22 |
|
R7148:Myom2
|
UTSW |
8 |
15,134,577 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7210:Myom2
|
UTSW |
8 |
15,154,114 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7298:Myom2
|
UTSW |
8 |
15,148,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7463:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably null |
0.94 |
|
R7535:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7573:Myom2
|
UTSW |
8 |
15,172,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7590:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7690:Myom2
|
UTSW |
8 |
15,161,717 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7794:Myom2
|
UTSW |
8 |
15,133,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7822:Myom2
|
UTSW |
8 |
15,158,454 (GRCm39) |
missense |
probably benign |
|
|
R7948:Myom2
|
UTSW |
8 |
15,135,306 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8094:Myom2
|
UTSW |
8 |
15,119,418 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8268:Myom2
|
UTSW |
8 |
15,179,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8292:Myom2
|
UTSW |
8 |
15,182,888 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8514:Myom2
|
UTSW |
8 |
15,175,153 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8539:Myom2
|
UTSW |
8 |
15,164,254 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8790:Myom2
|
UTSW |
8 |
15,169,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8824:Myom2
|
UTSW |
8 |
15,164,169 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8895:Myom2
|
UTSW |
8 |
15,152,589 (GRCm39) |
nonsense |
probably null |
|
|
R9024:Myom2
|
UTSW |
8 |
15,113,936 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9129:Myom2
|
UTSW |
8 |
15,154,068 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9224:Myom2
|
UTSW |
8 |
15,178,804 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9237:Myom2
|
UTSW |
8 |
15,152,591 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R9321:Myom2
|
UTSW |
8 |
15,172,464 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9341:Myom2
|
UTSW |
8 |
15,134,633 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9343:Myom2
|
UTSW |
8 |
15,134,633 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9375:Myom2
|
UTSW |
8 |
15,149,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9455:Myom2
|
UTSW |
8 |
15,156,293 (GRCm39) |
missense |
probably benign |
0.31 |
|
R9563:Myom2
|
UTSW |
8 |
15,158,399 (GRCm39) |
nonsense |
probably null |
|
|
R9565:Myom2
|
UTSW |
8 |
15,158,399 (GRCm39) |
nonsense |
probably null |
|
|
RF001:Myom2
|
UTSW |
8 |
15,131,418 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
| Predicted Primers |
|
| Posted On |
2013-04-11 |
Incidental Mutation