Incidental Mutation 'R1853:Ercc6'
| ID |
208359 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ercc6
|
| Ensembl Gene |
ENSMUSG00000054051 |
| Gene Name |
excision repair cross-complementing rodent repair deficiency, complementation group 6 |
| Synonyms |
CS group B correcting gene, C130058G22Rik, CSB |
| MMRRC Submission |
039877-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.422)
|
| Stock # |
R1853 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
14 |
| Chromosomal Location |
32235478-32302947 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 32298773 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Asparagine
at position 1387
(I1387N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000066256
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000066807]
|
| AlphaFold |
F8VPZ5 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000066807
AA Change: I1387N
PolyPhen 2
Score 0.858 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000066256
Gene: ENSMUSG00000054051
AA Change: I1387N
| Domain | Start | End | E-Value | Type |
|---|
|
PDB:4CVO|A
|
82 |
160 |
1e-36 |
PDB |
|
low complexity region
|
286 |
299 |
N/A |
INTRINSIC |
|
low complexity region
|
361 |
390 |
N/A |
INTRINSIC |
|
low complexity region
|
422 |
434 |
N/A |
INTRINSIC |
|
low complexity region
|
460 |
469 |
N/A |
INTRINSIC |
|
low complexity region
|
479 |
491 |
N/A |
INTRINSIC |
|
DEXDc
|
499 |
699 |
8.34e-33 |
SMART |
|
Blast:DEXDc
|
720 |
821 |
7e-56 |
BLAST |
|
HELICc
|
865 |
948 |
1.41e-21 |
SMART |
|
low complexity region
|
1364 |
1377 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000228549
|
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.1%
- 20x: 92.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Alternative splicing occurs between a splice site from exon 5 of this gene to the 3' splice site upstream of the open reading frame (ORF) of the adjacent gene, piggyback-derived-3 (GeneID:267004), which activates the alternative polyadenylation site downstream of the piggyback-derived-3 ORF. The resulting transcripts encode a fusion protein that shares sequence with the product of each individual gene. [provided by RefSeq, Mar 2016]
PHENOTYPE: Homozygous mutant mice exhibit UV sensitivity, inactivation of transcription-coupled repair, increased incidence of induced skin and eye tumors, circling behavior, impaired coordination and lower body weight. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acadvl |
T |
C |
11: 69,901,696 (GRCm39) |
K554E |
probably damaging |
Het |
| Acap2 |
C |
T |
16: 30,936,122 (GRCm39) |
E322K |
probably damaging |
Het |
| Adam32 |
T |
C |
8: 25,388,642 (GRCm39) |
Y354C |
probably benign |
Het |
| Agl |
A |
T |
3: 116,572,971 (GRCm39) |
Y789* |
probably null |
Het |
| Aida |
A |
G |
1: 183,087,380 (GRCm39) |
T68A |
probably benign |
Het |
| Aldh3b3 |
T |
A |
19: 4,015,822 (GRCm39) |
L264Q |
probably damaging |
Het |
| Anks6 |
T |
C |
4: 47,049,387 (GRCm39) |
T173A |
probably benign |
Het |
| Ankzf1 |
A |
G |
1: 75,174,772 (GRCm39) |
|
probably null |
Het |
| Apob |
A |
T |
12: 8,060,928 (GRCm39) |
K3137* |
probably null |
Het |
| Arhgef16 |
C |
T |
4: 154,375,563 (GRCm39) |
V144I |
probably benign |
Het |
| Arhgef2 |
A |
T |
3: 88,540,222 (GRCm39) |
T107S |
possibly damaging |
Het |
| Ark2c |
T |
A |
18: 77,550,671 (GRCm39) |
S279C |
possibly damaging |
Het |
| Atad2 |
G |
A |
15: 57,960,685 (GRCm39) |
P971L |
possibly damaging |
Het |
| Atp6ap1l |
T |
C |
13: 91,031,707 (GRCm39) |
E325G |
probably damaging |
Het |
| BC035947 |
T |
C |
1: 78,475,653 (GRCm39) |
N293S |
possibly damaging |
Het |
| Bhmt |
C |
T |
13: 93,761,843 (GRCm39) |
V147M |
probably damaging |
Het |
| Ccdc112 |
A |
T |
18: 46,418,767 (GRCm39) |
H447Q |
probably benign |
Het |
| Cd274 |
T |
A |
19: 29,357,882 (GRCm39) |
N191K |
probably damaging |
Het |
| Ckmt1 |
C |
T |
2: 121,191,131 (GRCm39) |
T181I |
probably damaging |
Het |
| Cnih3 |
C |
A |
1: 181,282,186 (GRCm39) |
S140* |
probably null |
Het |
| Col28a1 |
T |
G |
6: 8,014,574 (GRCm39) |
I944L |
probably benign |
Het |
| Cttnbp2 |
T |
C |
6: 18,408,601 (GRCm39) |
T1007A |
probably benign |
Het |
| Cux2 |
G |
T |
5: 122,007,184 (GRCm39) |
P826T |
possibly damaging |
Het |
| Cyren |
A |
G |
6: 34,852,494 (GRCm39) |
V67A |
probably damaging |
Het |
| Dap3 |
A |
T |
3: 88,838,233 (GRCm39) |
V86E |
probably damaging |
Het |
| Ddah1 |
A |
G |
3: 145,597,304 (GRCm39) |
I180M |
probably benign |
Het |
| Ddt |
T |
C |
10: 75,609,138 (GRCm39) |
E7G |
possibly damaging |
Het |
| Dhx57 |
A |
T |
17: 80,582,308 (GRCm39) |
Y432* |
probably null |
Het |
| Dpp9 |
T |
C |
17: 56,509,885 (GRCm39) |
I314V |
probably benign |
Het |
| Enpp2 |
C |
T |
15: 54,709,219 (GRCm39) |
E803K |
probably damaging |
Het |
| Fancg |
T |
C |
4: 43,009,727 (GRCm39) |
E57G |
probably benign |
Het |
| Fcgbpl1 |
C |
T |
7: 27,854,971 (GRCm39) |
Q1866* |
probably null |
Het |
| Fkbp5 |
A |
T |
17: 28,648,281 (GRCm39) |
C103S |
possibly damaging |
Het |
| Gm14403 |
C |
A |
2: 177,200,932 (GRCm39) |
H293N |
probably damaging |
Het |
| Gm4353 |
G |
A |
7: 115,682,804 (GRCm39) |
P259L |
probably benign |
Het |
| Gm4787 |
T |
A |
12: 81,425,108 (GRCm39) |
H350L |
probably damaging |
Het |
| Hibch |
T |
C |
1: 52,940,494 (GRCm39) |
|
probably null |
Het |
| Impg2 |
T |
C |
16: 56,080,640 (GRCm39) |
S815P |
probably damaging |
Het |
| Ipo11 |
A |
T |
13: 106,997,395 (GRCm39) |
I688K |
probably benign |
Het |
| Kcnd3 |
A |
T |
3: 105,367,068 (GRCm39) |
T313S |
probably damaging |
Het |
| Kctd14 |
A |
T |
7: 97,102,631 (GRCm39) |
S38C |
possibly damaging |
Het |
| Kdm3b |
G |
T |
18: 34,966,446 (GRCm39) |
R1660L |
probably damaging |
Het |
| Kdr |
C |
T |
5: 76,113,565 (GRCm39) |
G768S |
possibly damaging |
Het |
| Klhl2 |
G |
A |
8: 65,275,658 (GRCm39) |
H82Y |
probably benign |
Het |
| Lama3 |
A |
T |
18: 12,646,762 (GRCm39) |
T1759S |
possibly damaging |
Het |
| Lamb1 |
T |
G |
12: 31,368,271 (GRCm39) |
C1134G |
probably damaging |
Het |
| Macf1 |
T |
C |
4: 123,406,513 (GRCm39) |
|
probably null |
Het |
| Mlph |
C |
T |
1: 90,873,389 (GRCm39) |
Q567* |
probably null |
Het |
| Mocos |
A |
C |
18: 24,829,026 (GRCm39) |
E777A |
probably damaging |
Het |
| Neil1 |
T |
A |
9: 57,051,999 (GRCm39) |
Q214L |
probably damaging |
Het |
| Nes |
A |
G |
3: 87,883,114 (GRCm39) |
T458A |
possibly damaging |
Het |
| Nlgn1 |
A |
T |
3: 26,187,671 (GRCm39) |
N71K |
possibly damaging |
Het |
| Nr4a1 |
T |
C |
15: 101,169,645 (GRCm39) |
I305T |
probably benign |
Het |
| Nup58 |
T |
C |
14: 60,481,996 (GRCm39) |
T123A |
possibly damaging |
Het |
| Oas1c |
A |
T |
5: 120,946,060 (GRCm39) |
V146E |
probably damaging |
Het |
| Oit3 |
C |
T |
10: 59,277,444 (GRCm39) |
|
probably null |
Het |
| Or12k8 |
A |
T |
2: 36,975,232 (GRCm39) |
F176Y |
probably damaging |
Het |
| Or4k15c |
A |
G |
14: 50,321,577 (GRCm39) |
L187P |
probably damaging |
Het |
| Osbp |
T |
C |
19: 11,951,255 (GRCm39) |
S267P |
possibly damaging |
Het |
| Pclo |
T |
A |
5: 14,726,698 (GRCm39) |
|
probably benign |
Het |
| Pde9a |
C |
T |
17: 31,674,094 (GRCm39) |
P60S |
probably damaging |
Het |
| Pdia3 |
T |
C |
2: 121,262,144 (GRCm39) |
I205T |
probably benign |
Het |
| Pdia4 |
A |
T |
6: 47,790,161 (GRCm39) |
D26E |
unknown |
Het |
| Pds5a |
A |
G |
5: 65,781,372 (GRCm39) |
V1036A |
possibly damaging |
Het |
| Pitx3 |
C |
T |
19: 46,125,912 (GRCm39) |
G4R |
probably benign |
Het |
| Pnn |
T |
A |
12: 59,118,399 (GRCm39) |
N327K |
probably damaging |
Het |
| Pole |
T |
G |
5: 110,454,719 (GRCm39) |
I984R |
possibly damaging |
Het |
| Psme2 |
T |
A |
14: 55,825,936 (GRCm39) |
I124F |
probably damaging |
Het |
| Pstpip2 |
T |
A |
18: 77,959,499 (GRCm39) |
L198Q |
probably damaging |
Het |
| Siglece |
A |
G |
7: 43,309,360 (GRCm39) |
F66S |
probably benign |
Het |
| Slc1a6 |
T |
A |
10: 78,648,758 (GRCm39) |
V493E |
probably damaging |
Het |
| Snd1 |
T |
A |
6: 28,545,563 (GRCm39) |
I373N |
probably damaging |
Het |
| Srrm2 |
A |
G |
17: 24,039,499 (GRCm39) |
T2144A |
probably damaging |
Het |
| Sst |
A |
G |
16: 23,709,403 (GRCm39) |
L31P |
probably damaging |
Het |
| Stab1 |
C |
T |
14: 30,862,420 (GRCm39) |
V2305M |
probably damaging |
Het |
| Stard9 |
T |
C |
2: 120,519,232 (GRCm39) |
I545T |
probably damaging |
Het |
| Tcaim |
T |
C |
9: 122,655,271 (GRCm39) |
W248R |
probably damaging |
Het |
| Tepsin |
A |
C |
11: 119,989,462 (GRCm39) |
F13C |
probably damaging |
Het |
| Terf1 |
T |
A |
1: 15,889,162 (GRCm39) |
L197* |
probably null |
Het |
| Tiam2 |
C |
T |
17: 3,465,410 (GRCm39) |
R380C |
probably damaging |
Het |
| Tmem63b |
G |
A |
17: 45,972,223 (GRCm39) |
H745Y |
possibly damaging |
Het |
| Trim40 |
A |
G |
17: 37,199,970 (GRCm39) |
L36P |
probably damaging |
Het |
| Trim72 |
A |
G |
7: 127,608,254 (GRCm39) |
I251V |
probably benign |
Het |
| Trio |
T |
C |
15: 27,756,622 (GRCm39) |
Y914C |
probably damaging |
Het |
| Vmn2r113 |
G |
A |
17: 23,164,501 (GRCm39) |
V135I |
probably benign |
Het |
| Vmn2r117 |
T |
A |
17: 23,696,429 (GRCm39) |
H326L |
probably damaging |
Het |
| Vmn2r28 |
A |
T |
7: 5,484,246 (GRCm39) |
C651* |
probably null |
Het |
| Xpnpep1 |
T |
C |
19: 52,994,641 (GRCm39) |
E329G |
probably benign |
Het |
| Xpo4 |
G |
A |
14: 57,823,364 (GRCm39) |
T1042M |
possibly damaging |
Het |
| Ypel1 |
A |
C |
16: 16,925,087 (GRCm39) |
D28E |
probably benign |
Het |
| Zdbf2 |
GAAAAA |
GAAAAAA |
1: 63,344,701 (GRCm39) |
|
probably null |
Het |
| Zfp51 |
A |
T |
17: 21,684,585 (GRCm39) |
H400L |
probably damaging |
Het |
| Zfp518b |
A |
T |
5: 38,830,750 (GRCm39) |
F418L |
probably benign |
Het |
| Zfp54 |
T |
A |
17: 21,654,404 (GRCm39) |
Y299* |
probably null |
Het |
| Zfp672 |
T |
C |
11: 58,207,790 (GRCm39) |
H177R |
probably benign |
Het |
| Zfp692 |
C |
A |
11: 58,200,805 (GRCm39) |
P229T |
possibly damaging |
Het |
| Zswim4 |
A |
T |
8: 84,950,829 (GRCm39) |
C533S |
probably damaging |
Het |
|
| Other mutations in Ercc6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00321:Ercc6
|
APN |
14 |
32,290,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00796:Ercc6
|
APN |
14 |
32,291,959 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00916:Ercc6
|
APN |
14 |
32,284,612 (GRCm39) |
intron |
probably benign |
|
|
IGL01743:Ercc6
|
APN |
14 |
32,274,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01802:Ercc6
|
APN |
14 |
32,284,531 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01886:Ercc6
|
APN |
14 |
32,291,537 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02100:Ercc6
|
APN |
14 |
32,239,052 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02115:Ercc6
|
APN |
14 |
32,298,950 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02755:Ercc6
|
APN |
14 |
32,297,705 (GRCm39) |
splice site |
probably benign |
|
|
IGL02964:Ercc6
|
APN |
14 |
32,292,060 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02998:Ercc6
|
APN |
14 |
32,279,814 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL03150:Ercc6
|
APN |
14 |
32,280,531 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0152:Ercc6
|
UTSW |
14 |
32,268,862 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R0519:Ercc6
|
UTSW |
14 |
32,248,799 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0591:Ercc6
|
UTSW |
14 |
32,279,973 (GRCm39) |
splice site |
probably benign |
|
|
R0894:Ercc6
|
UTSW |
14 |
32,238,985 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0946:Ercc6
|
UTSW |
14 |
32,274,578 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1313:Ercc6
|
UTSW |
14 |
32,274,677 (GRCm39) |
splice site |
probably benign |
|
|
R1506:Ercc6
|
UTSW |
14 |
32,291,821 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1528:Ercc6
|
UTSW |
14 |
32,240,979 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1711:Ercc6
|
UTSW |
14 |
32,248,133 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1753:Ercc6
|
UTSW |
14 |
32,298,956 (GRCm39) |
missense |
probably benign |
|
|
R1795:Ercc6
|
UTSW |
14 |
32,238,985 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1843:Ercc6
|
UTSW |
14 |
32,268,777 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1859:Ercc6
|
UTSW |
14 |
32,248,735 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1912:Ercc6
|
UTSW |
14 |
32,298,760 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2308:Ercc6
|
UTSW |
14 |
32,288,366 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R2322:Ercc6
|
UTSW |
14 |
32,248,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2386:Ercc6
|
UTSW |
14 |
32,263,316 (GRCm39) |
splice site |
probably null |
|
|
R4170:Ercc6
|
UTSW |
14 |
32,288,754 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4369:Ercc6
|
UTSW |
14 |
32,239,164 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4389:Ercc6
|
UTSW |
14 |
32,296,865 (GRCm39) |
nonsense |
probably null |
|
|
R4747:Ercc6
|
UTSW |
14 |
32,291,864 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4811:Ercc6
|
UTSW |
14 |
32,296,886 (GRCm39) |
missense |
probably benign |
0.20 |
|
R4840:Ercc6
|
UTSW |
14 |
32,263,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4973:Ercc6
|
UTSW |
14 |
32,296,859 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5068:Ercc6
|
UTSW |
14 |
32,292,020 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5069:Ercc6
|
UTSW |
14 |
32,292,020 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5070:Ercc6
|
UTSW |
14 |
32,292,020 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5093:Ercc6
|
UTSW |
14 |
32,289,479 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5265:Ercc6
|
UTSW |
14 |
32,291,580 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5272:Ercc6
|
UTSW |
14 |
32,240,985 (GRCm39) |
nonsense |
probably null |
|
|
R5499:Ercc6
|
UTSW |
14 |
32,238,916 (GRCm39) |
start codon destroyed |
probably null |
0.98 |
|
R5795:Ercc6
|
UTSW |
14 |
32,248,309 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6258:Ercc6
|
UTSW |
14 |
32,279,813 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6260:Ercc6
|
UTSW |
14 |
32,279,813 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6267:Ercc6
|
UTSW |
14 |
32,248,360 (GRCm39) |
nonsense |
probably null |
|
|
R6291:Ercc6
|
UTSW |
14 |
32,291,943 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6296:Ercc6
|
UTSW |
14 |
32,248,360 (GRCm39) |
nonsense |
probably null |
|
|
R6361:Ercc6
|
UTSW |
14 |
32,239,067 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6500:Ercc6
|
UTSW |
14 |
32,248,780 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6555:Ercc6
|
UTSW |
14 |
32,239,064 (GRCm39) |
missense |
probably benign |
0.15 |
|
R6724:Ercc6
|
UTSW |
14 |
32,288,288 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6925:Ercc6
|
UTSW |
14 |
32,284,565 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7143:Ercc6
|
UTSW |
14 |
32,292,262 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7327:Ercc6
|
UTSW |
14 |
32,248,361 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7396:Ercc6
|
UTSW |
14 |
32,291,762 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7529:Ercc6
|
UTSW |
14 |
32,282,686 (GRCm39) |
nonsense |
probably null |
|
|
R7609:Ercc6
|
UTSW |
14 |
32,288,318 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7802:Ercc6
|
UTSW |
14 |
32,239,260 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7854:Ercc6
|
UTSW |
14 |
32,288,249 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7995:Ercc6
|
UTSW |
14 |
32,284,526 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8181:Ercc6
|
UTSW |
14 |
32,279,905 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8320:Ercc6
|
UTSW |
14 |
32,242,972 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8388:Ercc6
|
UTSW |
14 |
32,292,297 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R8479:Ercc6
|
UTSW |
14 |
32,248,363 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8831:Ercc6
|
UTSW |
14 |
32,282,784 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8849:Ercc6
|
UTSW |
14 |
32,291,565 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8912:Ercc6
|
UTSW |
14 |
32,248,211 (GRCm39) |
missense |
probably benign |
0.40 |
|
R9210:Ercc6
|
UTSW |
14 |
32,291,822 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9309:Ercc6
|
UTSW |
14 |
32,240,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9499:Ercc6
|
UTSW |
14 |
32,284,525 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9552:Ercc6
|
UTSW |
14 |
32,284,525 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9562:Ercc6
|
UTSW |
14 |
32,296,924 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9688:Ercc6
|
UTSW |
14 |
32,297,755 (GRCm39) |
missense |
probably benign |
|
|
R9699:Ercc6
|
UTSW |
14 |
32,282,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9743:Ercc6
|
UTSW |
14 |
32,298,943 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1176:Ercc6
|
UTSW |
14 |
32,248,444 (GRCm39) |
missense |
probably benign |
0.27 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCAGTTATCCTGAGGGTCCTC -3'
(R):5'- ACGGACAGCTTGGACTCAAAC -3'
Sequencing Primer
(F):5'- CTCACAGCCTTTGGGGAAGTAG -3'
(R):5'- TTGGACTCAAACTCCTGCAGG -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation