Incidental Mutation 'R1883:Epha7'
| ID |
209227 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Epha7
|
| Ensembl Gene |
ENSMUSG00000028289 |
| Gene Name |
Eph receptor A7 |
| Synonyms |
Ehk3, MDK1, Cek11, Mdk1, Hek11, Ebk |
| MMRRC Submission |
039904-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.548)
|
| Stock # |
R1883 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
28813131-28967499 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 28950362 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Tyrosine
at position 722
(H722Y)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000103826
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000029964]
[ENSMUST00000080934]
[ENSMUST00000108191]
[ENSMUST00000108194]
|
| AlphaFold |
Q61772 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000029964
AA Change: H726Y
PolyPhen 2
Score 0.154 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000029964
Gene: ENSMUSG00000028289
AA Change: H726Y
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
EPH_lbd
|
32 |
205 |
3.24e-126 |
SMART |
|
FN3
|
332 |
422 |
2.39e-8 |
SMART |
|
FN3
|
443 |
524 |
3.12e-12 |
SMART |
|
Pfam:EphA2_TM
|
557 |
630 |
4.4e-25 |
PFAM |
|
TyrKc
|
633 |
890 |
8.84e-139 |
SMART |
|
SAM
|
920 |
987 |
1.26e-23 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000080934
|
| SMART Domains |
Protein: ENSMUSP00000079735
Gene: ENSMUSG00000028289
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
EPH_lbd
|
32 |
205 |
3.24e-126 |
SMART |
|
FN3
|
332 |
422 |
2.39e-8 |
SMART |
|
FN3
|
443 |
524 |
3.12e-12 |
SMART |
|
transmembrane domain
|
556 |
578 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000108191
AA Change: H722Y
PolyPhen 2
Score 0.582 (Sensitivity: 0.88; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000103826
Gene: ENSMUSG00000028289
AA Change: H722Y
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
EPH_lbd
|
32 |
205 |
3.24e-126 |
SMART |
|
FN3
|
332 |
422 |
2.39e-8 |
SMART |
|
FN3
|
443 |
524 |
3.12e-12 |
SMART |
|
Pfam:EphA2_TM
|
556 |
626 |
2.9e-23 |
PFAM |
|
TyrKc
|
629 |
886 |
8.84e-139 |
SMART |
|
SAM
|
916 |
983 |
1.26e-23 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108194
|
| SMART Domains |
Protein: ENSMUSP00000103829
Gene: ENSMUSG00000028289
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
EPH_lbd
|
32 |
205 |
3.24e-126 |
SMART |
|
FN3
|
332 |
422 |
2.39e-8 |
SMART |
|
FN3
|
443 |
524 |
3.12e-12 |
SMART |
|
transmembrane domain
|
556 |
578 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000129912
|
| Coding Region Coverage |
- 1x: 97.3%
- 3x: 96.8%
- 10x: 95.4%
- 20x: 93.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Increased expression of this gene is associated with multiple forms of carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
PHENOTYPE: Some homozygous mutants display anencephaly. Mutants also exhibit increased proliferation of neural progenitor cells in the lateral ventricle wall of the adult brain. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ano9 |
T |
C |
7: 140,682,244 (GRCm39) |
E677G |
probably benign |
Het |
| Auh |
G |
A |
13: 52,989,532 (GRCm39) |
P308L |
probably benign |
Het |
| Bhmt1b |
T |
C |
18: 87,774,669 (GRCm39) |
L64P |
probably damaging |
Het |
| Brs3 |
T |
C |
X: 56,092,449 (GRCm39) |
I311T |
probably benign |
Het |
| Capn9 |
A |
G |
8: 125,338,297 (GRCm39) |
K552R |
probably benign |
Het |
| Catsperg1 |
C |
T |
7: 28,881,661 (GRCm39) |
|
probably null |
Het |
| Cdc16 |
A |
G |
8: 13,825,738 (GRCm39) |
N449D |
probably damaging |
Het |
| Cdyl2 |
A |
T |
8: 117,321,902 (GRCm39) |
N208K |
probably damaging |
Het |
| Cnot4 |
C |
T |
6: 35,055,092 (GRCm39) |
V66I |
probably damaging |
Het |
| Cntn4 |
A |
G |
6: 106,656,353 (GRCm39) |
T885A |
probably benign |
Het |
| Col20a1 |
C |
T |
2: 180,634,703 (GRCm39) |
T131I |
possibly damaging |
Het |
| Crybg2 |
C |
A |
4: 133,801,594 (GRCm39) |
S918* |
probably null |
Het |
| Dact2 |
A |
T |
17: 14,418,085 (GRCm39) |
S207T |
possibly damaging |
Het |
| Dbnl |
G |
A |
11: 5,749,247 (GRCm39) |
G356E |
probably benign |
Het |
| Ddx18 |
C |
A |
1: 121,495,645 (GRCm39) |
|
probably benign |
Het |
| Dis3 |
A |
T |
14: 99,328,905 (GRCm39) |
H282Q |
probably benign |
Het |
| Dnah3 |
T |
C |
7: 119,677,142 (GRCm39) |
D453G |
probably benign |
Het |
| Dst |
T |
C |
1: 34,228,389 (GRCm39) |
V1994A |
possibly damaging |
Het |
| Dusp8 |
C |
T |
7: 141,638,085 (GRCm39) |
|
probably null |
Het |
| Eipr1 |
A |
T |
12: 28,816,850 (GRCm39) |
H69L |
possibly damaging |
Het |
| Eml1 |
A |
G |
12: 108,429,911 (GRCm39) |
R65G |
probably damaging |
Het |
| Epyc |
A |
T |
10: 97,511,695 (GRCm39) |
K229N |
possibly damaging |
Het |
| Extl1 |
A |
G |
4: 134,091,917 (GRCm39) |
I312T |
probably benign |
Het |
| F13a1 |
G |
C |
13: 37,172,981 (GRCm39) |
A133G |
probably benign |
Het |
| Fam185a |
G |
T |
5: 21,630,242 (GRCm39) |
C26F |
possibly damaging |
Het |
| Fam186b |
T |
C |
15: 99,176,679 (GRCm39) |
N737S |
probably damaging |
Het |
| Fam78b |
A |
G |
1: 166,829,171 (GRCm39) |
I13V |
probably benign |
Het |
| Fat1 |
A |
T |
8: 45,504,184 (GRCm39) |
Q4559L |
probably benign |
Het |
| Fnip1 |
T |
C |
11: 54,406,373 (GRCm39) |
S1157P |
probably damaging |
Het |
| Foxj3 |
A |
C |
4: 119,467,226 (GRCm39) |
M190L |
probably benign |
Het |
| Heatr3 |
T |
C |
8: 88,871,221 (GRCm39) |
Y192H |
possibly damaging |
Het |
| Hexd |
T |
A |
11: 121,098,524 (GRCm39) |
S3T |
probably benign |
Het |
| Klf3 |
C |
T |
5: 64,980,224 (GRCm39) |
P5S |
probably damaging |
Het |
| Klf9 |
C |
T |
19: 23,142,101 (GRCm39) |
S187L |
probably damaging |
Het |
| Krt9 |
T |
C |
11: 100,079,523 (GRCm39) |
H623R |
unknown |
Het |
| Krtap2-4 |
G |
C |
11: 99,505,505 (GRCm39) |
|
probably benign |
Het |
| Lmtk3 |
T |
C |
7: 45,436,273 (GRCm39) |
Y84H |
probably damaging |
Het |
| Mroh3 |
G |
T |
1: 136,134,731 (GRCm39) |
A166D |
probably damaging |
Het |
| Musk |
C |
A |
4: 58,373,189 (GRCm39) |
P697T |
probably benign |
Het |
| Nek9 |
A |
G |
12: 85,379,330 (GRCm39) |
L192P |
probably damaging |
Het |
| Nipbl |
A |
C |
15: 8,356,616 (GRCm39) |
F1590C |
probably damaging |
Het |
| Nrk |
G |
T |
X: 137,907,922 (GRCm39) |
V1455F |
probably damaging |
Het |
| Nsun3 |
T |
C |
16: 62,555,656 (GRCm39) |
D290G |
probably damaging |
Het |
| Obscn |
T |
C |
11: 58,969,029 (GRCm39) |
T222A |
probably damaging |
Het |
| Or2a12 |
T |
C |
6: 42,904,764 (GRCm39) |
S200P |
probably damaging |
Het |
| Or51f1d |
T |
C |
7: 102,701,189 (GRCm39) |
I228T |
probably benign |
Het |
| Or6b9 |
T |
C |
7: 106,555,981 (GRCm39) |
H54R |
probably benign |
Het |
| Osbpl11 |
T |
G |
16: 33,034,723 (GRCm39) |
H237Q |
probably benign |
Het |
| Pde10a |
A |
T |
17: 9,197,776 (GRCm39) |
T671S |
possibly damaging |
Het |
| Pkd2 |
A |
T |
5: 104,631,094 (GRCm39) |
N506I |
probably damaging |
Het |
| Ppp3cb |
A |
G |
14: 20,573,913 (GRCm39) |
V274A |
possibly damaging |
Het |
| Prex1 |
T |
C |
2: 166,425,192 (GRCm39) |
D938G |
probably benign |
Het |
| Ptch1 |
G |
A |
13: 63,659,841 (GRCm39) |
Q1134* |
probably null |
Het |
| Rasgrf2 |
A |
G |
13: 92,117,149 (GRCm39) |
V820A |
probably benign |
Het |
| Rimbp2 |
C |
T |
5: 128,880,998 (GRCm39) |
V137M |
possibly damaging |
Het |
| Rpa1 |
A |
G |
11: 75,209,309 (GRCm39) |
V137A |
probably benign |
Het |
| Rps6ka1 |
A |
C |
4: 133,591,354 (GRCm39) |
I299S |
probably damaging |
Het |
| Scn3b |
A |
C |
9: 40,190,669 (GRCm39) |
|
probably null |
Het |
| Sdha |
A |
T |
13: 74,481,255 (GRCm39) |
I317N |
probably damaging |
Het |
| Serpina1d |
T |
A |
12: 103,732,037 (GRCm39) |
D274V |
possibly damaging |
Het |
| Sik3 |
C |
G |
9: 46,132,387 (GRCm39) |
H1276Q |
probably benign |
Het |
| Snx14 |
T |
A |
9: 88,284,314 (GRCm39) |
E451D |
probably benign |
Het |
| Spmip4 |
T |
C |
6: 50,551,433 (GRCm39) |
T339A |
probably benign |
Het |
| Swt1 |
T |
A |
1: 151,299,284 (GRCm39) |
K8* |
probably null |
Het |
| Tas1r3 |
G |
T |
4: 155,946,610 (GRCm39) |
P332T |
probably damaging |
Het |
| Tas2r126 |
A |
T |
6: 42,411,961 (GRCm39) |
T165S |
probably benign |
Het |
| Tecpr1 |
A |
G |
5: 144,143,347 (GRCm39) |
V676A |
probably benign |
Het |
| Tg |
A |
G |
15: 66,543,158 (GRCm39) |
E24G |
probably damaging |
Het |
| Tlr7 |
C |
T |
X: 166,089,468 (GRCm39) |
G673S |
probably benign |
Het |
| Tnxb |
T |
A |
17: 34,908,539 (GRCm39) |
D1520E |
probably benign |
Het |
| Trabd |
A |
G |
15: 88,966,184 (GRCm39) |
E47G |
probably damaging |
Het |
| Trim29 |
T |
A |
9: 43,222,702 (GRCm39) |
I177N |
probably damaging |
Het |
| Ubxn2a |
A |
T |
12: 4,944,563 (GRCm39) |
L53* |
probably null |
Het |
| Ulk2 |
A |
G |
11: 61,721,438 (GRCm39) |
L208P |
probably damaging |
Het |
| Unc80 |
G |
A |
1: 66,564,929 (GRCm39) |
C872Y |
possibly damaging |
Het |
| Vac14 |
A |
G |
8: 111,438,319 (GRCm39) |
H644R |
probably damaging |
Het |
| Vmn1r20 |
C |
A |
6: 57,409,306 (GRCm39) |
H211N |
probably benign |
Het |
| Vmn1r31 |
C |
T |
6: 58,449,029 (GRCm39) |
V279I |
probably damaging |
Het |
| Vmn2r18 |
G |
T |
5: 151,499,190 (GRCm39) |
Q425K |
probably benign |
Het |
| Vmn2r60 |
T |
C |
7: 41,786,094 (GRCm39) |
V299A |
probably damaging |
Het |
| Vps54 |
A |
T |
11: 21,262,967 (GRCm39) |
T685S |
possibly damaging |
Het |
| Vwa5b1 |
A |
G |
4: 138,302,700 (GRCm39) |
W932R |
probably damaging |
Het |
| Wdr53 |
A |
T |
16: 32,075,316 (GRCm39) |
I174F |
possibly damaging |
Het |
| Zfp157 |
A |
G |
5: 138,443,102 (GRCm39) |
D31G |
probably damaging |
Het |
| Zfp60 |
T |
C |
7: 27,449,435 (GRCm39) |
L701P |
probably benign |
Het |
| Zfp609 |
A |
T |
9: 65,702,040 (GRCm39) |
M204K |
probably benign |
Het |
| Zfp831 |
A |
G |
2: 174,545,870 (GRCm39) |
H1325R |
possibly damaging |
Het |
| Zfp995 |
A |
T |
17: 22,099,622 (GRCm39) |
I204N |
probably benign |
Het |
| Zp2 |
C |
T |
7: 119,732,624 (GRCm39) |
D641N |
probably benign |
Het |
|
| Other mutations in Epha7 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00811:Epha7
|
APN |
4 |
28,961,285 (GRCm39) |
intron |
probably benign |
|
|
IGL00849:Epha7
|
APN |
4 |
28,870,662 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
IGL00898:Epha7
|
APN |
4 |
28,938,693 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02036:Epha7
|
APN |
4 |
28,950,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02227:Epha7
|
APN |
4 |
28,821,587 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02237:Epha7
|
APN |
4 |
28,949,325 (GRCm39) |
splice site |
probably null |
|
|
IGL02376:Epha7
|
APN |
4 |
28,951,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02424:Epha7
|
APN |
4 |
28,948,790 (GRCm39) |
intron |
probably benign |
|
|
IGL02519:Epha7
|
APN |
4 |
28,821,494 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02522:Epha7
|
APN |
4 |
28,821,494 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02524:Epha7
|
APN |
4 |
28,821,494 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02602:Epha7
|
APN |
4 |
28,871,877 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
Pump
|
UTSW |
4 |
28,871,937 (GRCm39) |
missense |
probably benign |
0.07 |
|
PIT4514001:Epha7
|
UTSW |
4 |
28,961,355 (GRCm39) |
nonsense |
probably null |
|
|
R0001:Epha7
|
UTSW |
4 |
28,961,279 (GRCm39) |
intron |
probably benign |
|
|
R0011:Epha7
|
UTSW |
4 |
28,962,564 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0011:Epha7
|
UTSW |
4 |
28,962,564 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0310:Epha7
|
UTSW |
4 |
28,961,301 (GRCm39) |
missense |
probably benign |
0.33 |
|
R0373:Epha7
|
UTSW |
4 |
28,935,700 (GRCm39) |
splice site |
probably null |
|
|
R0496:Epha7
|
UTSW |
4 |
28,821,292 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0554:Epha7
|
UTSW |
4 |
28,951,401 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0632:Epha7
|
UTSW |
4 |
28,821,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1677:Epha7
|
UTSW |
4 |
28,947,571 (GRCm39) |
nonsense |
probably null |
|
|
R1919:Epha7
|
UTSW |
4 |
28,963,969 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R1952:Epha7
|
UTSW |
4 |
28,950,474 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1999:Epha7
|
UTSW |
4 |
28,938,686 (GRCm39) |
nonsense |
probably null |
|
|
R2187:Epha7
|
UTSW |
4 |
28,942,648 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R2308:Epha7
|
UTSW |
4 |
28,821,503 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R2417:Epha7
|
UTSW |
4 |
28,947,579 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3911:Epha7
|
UTSW |
4 |
28,938,680 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4350:Epha7
|
UTSW |
4 |
28,950,393 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4688:Epha7
|
UTSW |
4 |
28,821,367 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4702:Epha7
|
UTSW |
4 |
28,961,425 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4957:Epha7
|
UTSW |
4 |
28,871,892 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5364:Epha7
|
UTSW |
4 |
28,950,557 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5661:Epha7
|
UTSW |
4 |
28,946,217 (GRCm39) |
splice site |
probably null |
|
|
R5820:Epha7
|
UTSW |
4 |
28,949,365 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6038:Epha7
|
UTSW |
4 |
28,821,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6038:Epha7
|
UTSW |
4 |
28,821,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6592:Epha7
|
UTSW |
4 |
28,813,482 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6783:Epha7
|
UTSW |
4 |
28,950,528 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6991:Epha7
|
UTSW |
4 |
28,821,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7152:Epha7
|
UTSW |
4 |
28,935,826 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7232:Epha7
|
UTSW |
4 |
28,951,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7261:Epha7
|
UTSW |
4 |
28,813,418 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7365:Epha7
|
UTSW |
4 |
28,871,937 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7367:Epha7
|
UTSW |
4 |
28,871,937 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7368:Epha7
|
UTSW |
4 |
28,871,937 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7413:Epha7
|
UTSW |
4 |
28,871,838 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7603:Epha7
|
UTSW |
4 |
28,871,937 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7604:Epha7
|
UTSW |
4 |
28,871,937 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7605:Epha7
|
UTSW |
4 |
28,871,937 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7607:Epha7
|
UTSW |
4 |
28,871,937 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7608:Epha7
|
UTSW |
4 |
28,871,937 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7609:Epha7
|
UTSW |
4 |
28,871,937 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7610:Epha7
|
UTSW |
4 |
28,871,937 (GRCm39) |
missense |
probably benign |
0.07 |
|
R8073:Epha7
|
UTSW |
4 |
28,821,022 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8263:Epha7
|
UTSW |
4 |
28,821,149 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8334:Epha7
|
UTSW |
4 |
28,938,777 (GRCm39) |
missense |
probably benign |
0.26 |
|
R8866:Epha7
|
UTSW |
4 |
28,821,614 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8906:Epha7
|
UTSW |
4 |
28,821,615 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8914:Epha7
|
UTSW |
4 |
28,963,892 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9335:Epha7
|
UTSW |
4 |
28,966,529 (GRCm39) |
missense |
probably benign |
0.15 |
|
R9355:Epha7
|
UTSW |
4 |
28,935,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9576:Epha7
|
UTSW |
4 |
28,870,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9796:Epha7
|
UTSW |
4 |
28,817,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACCGCAGATCTATCATGTTGAC -3'
(R):5'- GTAGACAGCTTCGGGATCATC -3'
Sequencing Primer
(F):5'- TTGACCATCAACTAAAGCAGCATGTG -3'
(R):5'- GGGATCATCCTCTATAACCCGG -3'
|
| Posted On |
2014-06-30 |
Incidental Mutation