Incidental Mutation 'R1895:Cep295'
| ID |
209752 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cep295
|
| Ensembl Gene |
ENSMUSG00000046111 |
| Gene Name |
centrosomal protein 295 |
| Synonyms |
5830418K08Rik, LOC382128 |
| MMRRC Submission |
039915-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.952)
|
| Stock # |
R1895 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
15228211-15269084 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 15243399 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 1686
(T1686A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000123788
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000098979]
[ENSMUST00000161132]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000058041
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000059410
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000066038
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000098979
AA Change: T1686A
PolyPhen 2
Score 0.114 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000096578
Gene: ENSMUSG00000046111
AA Change: T1686A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
159 |
175 |
N/A |
INTRINSIC |
|
coiled coil region
|
258 |
288 |
N/A |
INTRINSIC |
|
coiled coil region
|
536 |
583 |
N/A |
INTRINSIC |
|
coiled coil region
|
861 |
889 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
890 |
1104 |
6.8e-5 |
PROSPERO |
|
internal_repeat_1
|
1277 |
1489 |
6.8e-5 |
PROSPERO |
|
low complexity region
|
1537 |
1548 |
N/A |
INTRINSIC |
|
low complexity region
|
1611 |
1625 |
N/A |
INTRINSIC |
|
coiled coil region
|
1707 |
1736 |
N/A |
INTRINSIC |
|
low complexity region
|
2003 |
2018 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000160946
AA Change: T430A
|
| SMART Domains |
Protein: ENSMUSP00000125494
Gene: ENSMUSG00000046111
AA Change: T430A
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
92 |
119 |
N/A |
INTRINSIC |
|
low complexity region
|
282 |
293 |
N/A |
INTRINSIC |
|
low complexity region
|
356 |
370 |
N/A |
INTRINSIC |
|
coiled coil region
|
451 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
828 |
843 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000161132
AA Change: T1686A
PolyPhen 2
Score 0.944 (Sensitivity: 0.80; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000123788
Gene: ENSMUSG00000046111
AA Change: T1686A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
111 |
127 |
N/A |
INTRINSIC |
|
coiled coil region
|
210 |
240 |
N/A |
INTRINSIC |
|
coiled coil region
|
488 |
535 |
N/A |
INTRINSIC |
|
coiled coil region
|
813 |
841 |
N/A |
INTRINSIC |
|
coiled coil region
|
1300 |
1327 |
N/A |
INTRINSIC |
|
low complexity region
|
1489 |
1500 |
N/A |
INTRINSIC |
|
low complexity region
|
1563 |
1577 |
N/A |
INTRINSIC |
|
coiled coil region
|
1659 |
1688 |
N/A |
INTRINSIC |
|
low complexity region
|
2035 |
2050 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000161795
AA Change: T1638A
PolyPhen 2
Score 0.023 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000125035
Gene: ENSMUSG00000046111
AA Change: T1638A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
111 |
127 |
N/A |
INTRINSIC |
|
coiled coil region
|
210 |
240 |
N/A |
INTRINSIC |
|
coiled coil region
|
488 |
535 |
N/A |
INTRINSIC |
|
coiled coil region
|
813 |
841 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
842 |
1056 |
7.14e-5 |
PROSPERO |
|
internal_repeat_1
|
1229 |
1441 |
7.14e-5 |
PROSPERO |
|
low complexity region
|
1489 |
1500 |
N/A |
INTRINSIC |
|
low complexity region
|
1563 |
1577 |
N/A |
INTRINSIC |
|
coiled coil region
|
1659 |
1688 |
N/A |
INTRINSIC |
|
low complexity region
|
1955 |
1970 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162264
|
| Meta Mutation Damage Score |
0.0773 |
| Coding Region Coverage |
- 1x: 97.1%
- 3x: 96.2%
- 10x: 93.2%
- 20x: 86.6%
|
| Validation Efficiency |
96% (100/104) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aasdh |
A |
G |
5: 77,039,551 (GRCm39) |
S253P |
probably damaging |
Het |
| Adgrb1 |
A |
G |
15: 74,412,314 (GRCm39) |
D431G |
probably damaging |
Het |
| Adgrv1 |
C |
T |
13: 81,522,368 (GRCm39) |
C5923Y |
probably damaging |
Het |
| Akr1b10 |
T |
A |
6: 34,365,805 (GRCm39) |
I110N |
probably damaging |
Het |
| Apba2 |
T |
C |
7: 64,394,378 (GRCm39) |
|
probably null |
Het |
| Arhgef12 |
G |
T |
9: 42,917,152 (GRCm39) |
Q396K |
probably damaging |
Het |
| Arpc1b |
A |
G |
5: 145,059,443 (GRCm39) |
T56A |
probably null |
Het |
| Atoh1 |
T |
C |
6: 64,706,443 (GRCm39) |
V46A |
probably benign |
Het |
| AU015836 |
T |
C |
X: 93,012,985 (GRCm39) |
|
probably benign |
Het |
| Cacna1c |
C |
T |
6: 118,589,586 (GRCm39) |
R1446H |
probably damaging |
Het |
| Capn13 |
T |
C |
17: 73,657,520 (GRCm39) |
E240G |
possibly damaging |
Het |
| Cdh8 |
T |
C |
8: 100,006,189 (GRCm39) |
T133A |
possibly damaging |
Het |
| Col4a3 |
A |
T |
1: 82,656,829 (GRCm39) |
K749N |
unknown |
Het |
| Col6a3 |
T |
A |
1: 90,731,433 (GRCm39) |
M1000L |
probably benign |
Het |
| Coq8b |
G |
A |
7: 26,939,299 (GRCm39) |
V150I |
possibly damaging |
Het |
| Dmxl1 |
G |
T |
18: 50,088,981 (GRCm39) |
|
probably null |
Het |
| Dnah10 |
A |
G |
5: 124,835,494 (GRCm39) |
D990G |
probably benign |
Het |
| Dpp7 |
G |
T |
2: 25,243,691 (GRCm39) |
|
probably null |
Het |
| Eif3l |
A |
G |
15: 78,973,677 (GRCm39) |
N364S |
possibly damaging |
Het |
| Epb41l5 |
T |
C |
1: 119,476,902 (GRCm39) |
D718G |
possibly damaging |
Het |
| F930017D23Rik |
G |
A |
10: 43,469,440 (GRCm39) |
|
noncoding transcript |
Het |
| Fam20a |
T |
C |
11: 109,564,380 (GRCm39) |
K458E |
probably benign |
Het |
| Fbxo44 |
C |
G |
4: 148,240,726 (GRCm39) |
R220S |
probably damaging |
Het |
| Fut2 |
A |
G |
7: 45,300,748 (GRCm39) |
F8S |
probably damaging |
Het |
| Gad2 |
A |
T |
2: 22,575,440 (GRCm39) |
T515S |
probably benign |
Het |
| Glmn |
T |
C |
5: 107,718,110 (GRCm39) |
D269G |
probably benign |
Het |
| Gpatch4 |
A |
G |
3: 87,959,409 (GRCm39) |
Y106C |
probably damaging |
Het |
| Grm3 |
A |
G |
5: 9,562,123 (GRCm39) |
W576R |
probably damaging |
Het |
| Hdac7 |
T |
C |
15: 97,694,767 (GRCm39) |
D701G |
probably damaging |
Het |
| Hectd2 |
T |
A |
19: 36,591,860 (GRCm39) |
I687K |
probably damaging |
Het |
| Hmcn2 |
T |
C |
2: 31,295,647 (GRCm39) |
S2619P |
probably damaging |
Het |
| Ilf3 |
T |
A |
9: 21,316,063 (GRCm39) |
|
probably benign |
Het |
| Kdm4b |
T |
A |
17: 56,704,340 (GRCm39) |
V272E |
probably damaging |
Het |
| Kera |
A |
G |
10: 97,445,009 (GRCm39) |
K123E |
probably benign |
Het |
| Kif11 |
G |
A |
19: 37,375,847 (GRCm39) |
R220K |
probably damaging |
Het |
| Kmt2c |
A |
T |
5: 25,520,152 (GRCm39) |
V1986E |
probably benign |
Het |
| Lrp11 |
T |
C |
10: 7,499,540 (GRCm39) |
Y244H |
probably damaging |
Het |
| Lrp1b |
T |
A |
2: 40,555,159 (GRCm39) |
D320V |
unknown |
Het |
| Map4k5 |
A |
T |
12: 69,892,529 (GRCm39) |
D133E |
probably damaging |
Het |
| Megf11 |
A |
T |
9: 64,586,558 (GRCm39) |
D461V |
probably damaging |
Het |
| Muc5b |
A |
C |
7: 141,411,382 (GRCm39) |
T1443P |
unknown |
Het |
| Mxi1 |
G |
A |
19: 53,358,775 (GRCm39) |
R236H |
probably benign |
Het |
| Nav1 |
A |
T |
1: 135,386,396 (GRCm39) |
W1211R |
probably damaging |
Het |
| Ncoa3 |
T |
A |
2: 165,901,097 (GRCm39) |
N896K |
possibly damaging |
Het |
| Nmt2 |
T |
A |
2: 3,323,672 (GRCm39) |
I355N |
probably benign |
Het |
| Nxpe5 |
T |
C |
5: 138,249,785 (GRCm39) |
V525A |
probably damaging |
Het |
| Oas1f |
A |
T |
5: 120,993,648 (GRCm39) |
T287S |
probably benign |
Het |
| Or1n1b |
A |
T |
2: 36,780,458 (GRCm39) |
M134K |
possibly damaging |
Het |
| Or5ae1 |
T |
C |
7: 84,565,487 (GRCm39) |
S167P |
probably benign |
Het |
| Or6ae1 |
T |
A |
7: 139,742,726 (GRCm39) |
I46F |
possibly damaging |
Het |
| Or7a38 |
T |
A |
10: 78,752,758 (GRCm39) |
I28N |
probably damaging |
Het |
| Or8b3 |
T |
A |
9: 38,314,182 (GRCm39) |
M1K |
probably null |
Het |
| Pakap |
T |
C |
4: 57,638,068 (GRCm39) |
V35A |
probably benign |
Het |
| Panx1 |
A |
G |
9: 14,918,822 (GRCm39) |
C346R |
probably benign |
Het |
| Plekha7 |
T |
C |
7: 115,744,209 (GRCm39) |
E764G |
probably damaging |
Het |
| Plet1 |
A |
G |
9: 50,415,652 (GRCm39) |
|
probably null |
Het |
| Plod2 |
A |
G |
9: 92,489,188 (GRCm39) |
S707G |
probably damaging |
Het |
| Plscr4 |
G |
A |
9: 92,365,889 (GRCm39) |
V120I |
probably damaging |
Het |
| Pramel31 |
T |
A |
4: 144,088,435 (GRCm39) |
V77E |
probably benign |
Het |
| Prob1 |
T |
A |
18: 35,785,942 (GRCm39) |
T771S |
possibly damaging |
Het |
| Rasa3 |
A |
G |
8: 13,681,768 (GRCm39) |
|
probably benign |
Het |
| Ror2 |
T |
C |
13: 53,285,885 (GRCm39) |
I110V |
probably damaging |
Het |
| Sec24d |
A |
T |
3: 123,147,043 (GRCm39) |
H667L |
probably benign |
Het |
| Sema3d |
A |
G |
5: 12,623,810 (GRCm39) |
Q573R |
probably damaging |
Het |
| Serpinb2 |
T |
A |
1: 107,452,337 (GRCm39) |
V305D |
probably damaging |
Het |
| Slc11a2 |
G |
A |
15: 100,301,775 (GRCm39) |
R249C |
probably benign |
Het |
| Slc14a1 |
T |
C |
18: 78,152,912 (GRCm39) |
I276V |
possibly damaging |
Het |
| Snx19 |
T |
A |
9: 30,343,620 (GRCm39) |
N593K |
probably damaging |
Het |
| Ssh2 |
C |
G |
11: 77,340,571 (GRCm39) |
D574E |
probably damaging |
Het |
| Stil |
T |
C |
4: 114,881,072 (GRCm39) |
S539P |
probably benign |
Het |
| Syt4 |
T |
C |
18: 31,577,141 (GRCm39) |
K71R |
probably damaging |
Het |
| Tenm4 |
A |
T |
7: 96,385,015 (GRCm39) |
H524L |
probably damaging |
Het |
| Tex30 |
C |
T |
1: 44,130,564 (GRCm39) |
G68D |
probably damaging |
Het |
| Tm4sf19 |
A |
G |
16: 32,226,500 (GRCm39) |
Y138C |
probably damaging |
Het |
| Tmem43 |
A |
T |
6: 91,463,891 (GRCm39) |
I389F |
probably benign |
Het |
| Trpm1 |
A |
T |
7: 63,873,556 (GRCm39) |
N488Y |
probably damaging |
Het |
| Tshz1 |
A |
T |
18: 84,031,558 (GRCm39) |
L950Q |
probably damaging |
Het |
| Vmn1r16 |
T |
C |
6: 57,299,885 (GRCm39) |
I246V |
probably benign |
Het |
| Vmn1r188 |
T |
G |
13: 22,272,815 (GRCm39) |
S256R |
possibly damaging |
Het |
| Zfp12 |
G |
A |
5: 143,231,133 (GRCm39) |
E487K |
probably damaging |
Het |
|
| Other mutations in Cep295 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00337:Cep295
|
APN |
9 |
15,237,368 (GRCm39) |
splice site |
probably null |
|
|
IGL00769:Cep295
|
APN |
9 |
15,237,440 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00771:Cep295
|
APN |
9 |
15,233,861 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00850:Cep295
|
APN |
9 |
15,234,148 (GRCm39) |
missense |
probably benign |
0.36 |
|
IGL01505:Cep295
|
APN |
9 |
15,229,345 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL01510:Cep295
|
APN |
9 |
15,265,922 (GRCm39) |
nonsense |
probably null |
|
|
IGL01759:Cep295
|
APN |
9 |
15,234,855 (GRCm39) |
splice site |
probably null |
|
|
IGL02415:Cep295
|
APN |
9 |
15,264,316 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02447:Cep295
|
APN |
9 |
15,243,807 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02502:Cep295
|
APN |
9 |
15,262,209 (GRCm39) |
splice site |
probably benign |
|
|
IGL02665:Cep295
|
APN |
9 |
15,237,928 (GRCm39) |
splice site |
probably benign |
|
|
IGL02718:Cep295
|
APN |
9 |
15,237,049 (GRCm39) |
splice site |
probably null |
|
|
IGL02995:Cep295
|
APN |
9 |
15,244,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03024:Cep295
|
APN |
9 |
15,236,868 (GRCm39) |
missense |
probably benign |
|
|
R0196:Cep295
|
UTSW |
9 |
15,249,509 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0398:Cep295
|
UTSW |
9 |
15,266,032 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0595:Cep295
|
UTSW |
9 |
15,243,487 (GRCm39) |
nonsense |
probably null |
|
|
R0610:Cep295
|
UTSW |
9 |
15,234,050 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R0616:Cep295
|
UTSW |
9 |
15,243,618 (GRCm39) |
nonsense |
probably null |
|
|
R0840:Cep295
|
UTSW |
9 |
15,245,611 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1215:Cep295
|
UTSW |
9 |
15,239,178 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1376:Cep295
|
UTSW |
9 |
15,252,164 (GRCm39) |
splice site |
probably benign |
|
|
R1381:Cep295
|
UTSW |
9 |
15,233,861 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1484:Cep295
|
UTSW |
9 |
15,246,080 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1557:Cep295
|
UTSW |
9 |
15,243,306 (GRCm39) |
nonsense |
probably null |
|
|
R1655:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1682:Cep295
|
UTSW |
9 |
15,245,217 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1700:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1734:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1736:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1743:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1765:Cep295
|
UTSW |
9 |
15,239,200 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1889:Cep295
|
UTSW |
9 |
15,243,399 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1994:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1995:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2071:Cep295
|
UTSW |
9 |
15,252,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2161:Cep295
|
UTSW |
9 |
15,264,354 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2195:Cep295
|
UTSW |
9 |
15,243,617 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2354:Cep295
|
UTSW |
9 |
15,246,080 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2427:Cep295
|
UTSW |
9 |
15,245,534 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2992:Cep295
|
UTSW |
9 |
15,244,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3873:Cep295
|
UTSW |
9 |
15,244,661 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3981:Cep295
|
UTSW |
9 |
15,228,363 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R4201:Cep295
|
UTSW |
9 |
15,243,834 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4297:Cep295
|
UTSW |
9 |
15,233,950 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4543:Cep295
|
UTSW |
9 |
15,246,549 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4584:Cep295
|
UTSW |
9 |
15,246,095 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R4724:Cep295
|
UTSW |
9 |
15,242,128 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4878:Cep295
|
UTSW |
9 |
15,246,252 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4884:Cep295
|
UTSW |
9 |
15,263,056 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4934:Cep295
|
UTSW |
9 |
15,244,456 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4990:Cep295
|
UTSW |
9 |
15,243,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5057:Cep295
|
UTSW |
9 |
15,233,979 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5153:Cep295
|
UTSW |
9 |
15,268,925 (GRCm39) |
missense |
probably benign |
0.32 |
|
R5180:Cep295
|
UTSW |
9 |
15,243,416 (GRCm39) |
missense |
probably benign |
|
|
R5285:Cep295
|
UTSW |
9 |
15,233,887 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5360:Cep295
|
UTSW |
9 |
15,238,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5419:Cep295
|
UTSW |
9 |
15,235,533 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5432:Cep295
|
UTSW |
9 |
15,262,991 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5625:Cep295
|
UTSW |
9 |
15,252,187 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5637:Cep295
|
UTSW |
9 |
15,245,108 (GRCm39) |
splice site |
probably null |
|
|
R5645:Cep295
|
UTSW |
9 |
15,246,404 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5645:Cep295
|
UTSW |
9 |
15,244,090 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5678:Cep295
|
UTSW |
9 |
15,234,154 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5688:Cep295
|
UTSW |
9 |
15,243,282 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5807:Cep295
|
UTSW |
9 |
15,243,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5824:Cep295
|
UTSW |
9 |
15,236,952 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5837:Cep295
|
UTSW |
9 |
15,258,280 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5915:Cep295
|
UTSW |
9 |
15,252,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5988:Cep295
|
UTSW |
9 |
15,252,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6239:Cep295
|
UTSW |
9 |
15,233,927 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6332:Cep295
|
UTSW |
9 |
15,246,210 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6383:Cep295
|
UTSW |
9 |
15,244,050 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6737:Cep295
|
UTSW |
9 |
15,243,647 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6929:Cep295
|
UTSW |
9 |
15,244,358 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7428:Cep295
|
UTSW |
9 |
15,244,794 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R7697:Cep295
|
UTSW |
9 |
15,266,006 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7963:Cep295
|
UTSW |
9 |
15,244,737 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8055:Cep295
|
UTSW |
9 |
15,244,905 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8069:Cep295
|
UTSW |
9 |
15,233,882 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8092:Cep295
|
UTSW |
9 |
15,244,278 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8117:Cep295
|
UTSW |
9 |
15,245,660 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8140:Cep295
|
UTSW |
9 |
15,252,829 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8178:Cep295
|
UTSW |
9 |
15,244,836 (GRCm39) |
missense |
|
|
|
R8323:Cep295
|
UTSW |
9 |
15,264,357 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8323:Cep295
|
UTSW |
9 |
15,249,529 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8339:Cep295
|
UTSW |
9 |
15,236,846 (GRCm39) |
missense |
|
|
|
R8351:Cep295
|
UTSW |
9 |
15,234,202 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8367:Cep295
|
UTSW |
9 |
15,245,826 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8725:Cep295
|
UTSW |
9 |
15,243,715 (GRCm39) |
nonsense |
probably null |
|
|
R8919:Cep295
|
UTSW |
9 |
15,238,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9015:Cep295
|
UTSW |
9 |
15,244,264 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9054:Cep295
|
UTSW |
9 |
15,235,551 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9088:Cep295
|
UTSW |
9 |
15,233,815 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9159:Cep295
|
UTSW |
9 |
15,252,904 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9243:Cep295
|
UTSW |
9 |
15,243,605 (GRCm39) |
missense |
probably benign |
0.36 |
|
R9408:Cep295
|
UTSW |
9 |
15,244,619 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9424:Cep295
|
UTSW |
9 |
15,244,499 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9455:Cep295
|
UTSW |
9 |
15,245,046 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9607:Cep295
|
UTSW |
9 |
15,234,009 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9648:Cep295
|
UTSW |
9 |
15,234,903 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9659:Cep295
|
UTSW |
9 |
15,233,846 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9731:Cep295
|
UTSW |
9 |
15,245,262 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
X0065:Cep295
|
UTSW |
9 |
15,234,187 (GRCm39) |
missense |
probably benign |
0.36 |
|
Z1176:Cep295
|
UTSW |
9 |
15,268,993 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Cep295
|
UTSW |
9 |
15,242,113 (GRCm39) |
missense |
|
|
|
| Predicted Primers |
PCR Primer
(F):5'- TTATCTGAGAACCCACTGCAAC -3'
(R):5'- TGTTTCTGTCCAAGGAAATAGAGC -3'
Sequencing Primer
(F):5'- TTAAATTCAGAACATACCTGACTGAC -3'
(R):5'- TGTCCAAGGAAATAGAGCATCCATTC -3'
|
| Posted On |
2014-06-30 |
Incidental Mutation