Incidental Mutation 'R1908:Apc2'
| ID |
210073 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Apc2
|
| Ensembl Gene |
ENSMUSG00000020135 |
| Gene Name |
APC regulator of WNT signaling pathway 2 |
| Synonyms |
APCL |
| MMRRC Submission |
039927-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.172)
|
| Stock # |
R1908 (G1)
|
| Quality Score |
219 |
|
Status
|
Not validated
|
| Chromosome |
10 |
| Chromosomal Location |
80131811-80154097 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 80150678 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Alanine
at position 1911
(S1911A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000100996
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000020341]
[ENSMUST00000020349]
[ENSMUST00000105359]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000020341
|
| SMART Domains |
Protein: ENSMUSP00000020341
Gene: ENSMUSG00000020133
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:UPF0449
|
6 |
103 |
7.5e-40 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000020349
AA Change: S1882A
PolyPhen 2
Score 0.021 (Sensitivity: 0.95; Specificity: 0.80)
|
| SMART Domains |
Protein: ENSMUSP00000020349
Gene: ENSMUSG00000020135
AA Change: S1882A
| Domain | Start | End | E-Value | Type |
|---|
|
PDB:1DEB|B
|
4 |
57 |
9e-17 |
PDB |
|
Pfam:Suppressor_APC
|
123 |
205 |
1.3e-28 |
PFAM |
|
coiled coil region
|
214 |
236 |
N/A |
INTRINSIC |
|
low complexity region
|
242 |
261 |
N/A |
INTRINSIC |
|
ARM
|
300 |
355 |
2.95e0 |
SMART |
|
ARM
|
417 |
468 |
2.22e-2 |
SMART |
|
ARM
|
470 |
511 |
3.22e0 |
SMART |
|
ARM
|
513 |
555 |
3.56e-1 |
SMART |
|
ARM
|
557 |
602 |
2.1e1 |
SMART |
|
ARM
|
607 |
647 |
1.82e-7 |
SMART |
|
Blast:ARM
|
649 |
689 |
6e-18 |
BLAST |
|
low complexity region
|
772 |
792 |
N/A |
INTRINSIC |
|
low complexity region
|
817 |
844 |
N/A |
INTRINSIC |
|
low complexity region
|
859 |
870 |
N/A |
INTRINSIC |
|
low complexity region
|
971 |
980 |
N/A |
INTRINSIC |
|
low complexity region
|
1057 |
1069 |
N/A |
INTRINSIC |
|
low complexity region
|
1087 |
1103 |
N/A |
INTRINSIC |
|
Pfam:APC_crr
|
1134 |
1159 |
4.4e-9 |
PFAM |
|
low complexity region
|
1197 |
1208 |
N/A |
INTRINSIC |
|
Pfam:APC_crr
|
1244 |
1269 |
4.1e-8 |
PFAM |
|
Pfam:SAMP
|
1323 |
1343 |
2.1e-10 |
PFAM |
|
Pfam:APC_crr
|
1369 |
1394 |
5.8e-8 |
PFAM |
|
low complexity region
|
1500 |
1516 |
N/A |
INTRINSIC |
|
Pfam:APC_crr
|
1540 |
1565 |
5.7e-8 |
PFAM |
|
Pfam:SAMP
|
1594 |
1613 |
8.8e-11 |
PFAM |
|
low complexity region
|
1673 |
1699 |
N/A |
INTRINSIC |
|
Pfam:APC_basic
|
1757 |
2093 |
1.1e-142 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000105359
AA Change: S1911A
PolyPhen 2
Score 0.047 (Sensitivity: 0.94; Specificity: 0.83)
|
| SMART Domains |
Protein: ENSMUSP00000100996
Gene: ENSMUSG00000020135
AA Change: S1911A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Pfam:APC_N_CC
|
30 |
81 |
2.7e-34 |
PFAM |
|
Pfam:Suppressor_APC
|
148 |
228 |
1.4e-27 |
PFAM |
|
coiled coil region
|
238 |
260 |
N/A |
INTRINSIC |
|
low complexity region
|
266 |
285 |
N/A |
INTRINSIC |
|
ARM
|
324 |
379 |
2.95e0 |
SMART |
|
ARM
|
446 |
497 |
2.22e-2 |
SMART |
|
ARM
|
499 |
540 |
3.22e0 |
SMART |
|
ARM
|
542 |
584 |
3.56e-1 |
SMART |
|
ARM
|
586 |
631 |
2.1e1 |
SMART |
|
ARM
|
636 |
676 |
1.82e-7 |
SMART |
|
Blast:ARM
|
678 |
718 |
6e-18 |
BLAST |
|
Pfam:Arm_APC_u3
|
719 |
977 |
1.1e-26 |
PFAM |
|
low complexity region
|
1000 |
1009 |
N/A |
INTRINSIC |
|
low complexity region
|
1086 |
1098 |
N/A |
INTRINSIC |
|
low complexity region
|
1116 |
1132 |
N/A |
INTRINSIC |
|
Pfam:APC_crr
|
1164 |
1187 |
9.3e-8 |
PFAM |
|
low complexity region
|
1226 |
1237 |
N/A |
INTRINSIC |
|
Pfam:APC_crr
|
1274 |
1297 |
7.9e-10 |
PFAM |
|
Pfam:APC_crr
|
1399 |
1423 |
1.3e-9 |
PFAM |
|
low complexity region
|
1529 |
1545 |
N/A |
INTRINSIC |
|
low complexity region
|
1585 |
1603 |
N/A |
INTRINSIC |
|
Pfam:SAMP
|
1624 |
1642 |
1.3e-11 |
PFAM |
|
low complexity region
|
1702 |
1728 |
N/A |
INTRINSIC |
|
Pfam:APC_basic
|
1786 |
2122 |
1.3e-122 |
PFAM |
|
| Coding Region Coverage |
- 1x: 97.3%
- 3x: 96.8%
- 10x: 95.4%
- 20x: 93.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a null allele display gradual postnatal growth retardation, abnormal lamination of the cerebral cortex, hippocampus, olfactory bulb and cerebellum, impaired neuronal migration and impaired coordination. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca8b |
C |
A |
11: 109,847,924 (GRCm39) |
L852F |
possibly damaging |
Het |
| Abcc6 |
T |
C |
7: 45,669,558 (GRCm39) |
|
probably null |
Het |
| Alg11 |
T |
G |
8: 22,555,584 (GRCm39) |
C240G |
probably damaging |
Het |
| Aox1 |
A |
G |
1: 58,141,783 (GRCm39) |
I1190V |
probably damaging |
Het |
| Arfgef3 |
T |
C |
10: 18,528,511 (GRCm39) |
D292G |
possibly damaging |
Het |
| Arhgef4 |
C |
A |
1: 34,763,340 (GRCm39) |
S865R |
probably benign |
Het |
| Ass1 |
T |
A |
2: 31,383,160 (GRCm39) |
Y190* |
probably null |
Het |
| B4galnt3 |
A |
T |
6: 120,187,051 (GRCm39) |
|
probably null |
Het |
| Btnl10 |
C |
A |
11: 58,811,367 (GRCm39) |
P230Q |
possibly damaging |
Het |
| C3 |
A |
G |
17: 57,516,489 (GRCm39) |
Y1348H |
probably damaging |
Het |
| Ccdc198 |
G |
T |
14: 49,464,032 (GRCm39) |
D292E |
probably damaging |
Het |
| Cebpz |
A |
T |
17: 79,242,336 (GRCm39) |
Y439* |
probably null |
Het |
| Cic |
C |
A |
7: 24,986,265 (GRCm39) |
T1229K |
probably damaging |
Het |
| Clip4 |
T |
C |
17: 72,144,744 (GRCm39) |
S524P |
probably damaging |
Het |
| Col6a3 |
A |
C |
1: 90,739,421 (GRCm39) |
I269R |
probably damaging |
Het |
| Dbh |
C |
T |
2: 27,071,506 (GRCm39) |
T533I |
possibly damaging |
Het |
| Dcaf17 |
A |
T |
2: 70,890,713 (GRCm39) |
R83* |
probably null |
Het |
| Dennd2b |
G |
A |
7: 109,124,533 (GRCm39) |
Q686* |
probably null |
Het |
| Dnah1 |
A |
G |
14: 30,984,515 (GRCm39) |
L3923P |
probably damaging |
Het |
| Dnah7a |
A |
T |
1: 53,670,721 (GRCm39) |
D510E |
probably benign |
Het |
| Dock6 |
A |
G |
9: 21,752,925 (GRCm39) |
F296S |
probably damaging |
Het |
| Eif4enif1 |
T |
C |
11: 3,177,455 (GRCm39) |
S341P |
probably damaging |
Het |
| Epb41l1 |
G |
T |
2: 156,352,737 (GRCm39) |
G461V |
possibly damaging |
Het |
| Epg5 |
T |
A |
18: 78,002,247 (GRCm39) |
D555E |
probably benign |
Het |
| Fes |
T |
C |
7: 80,036,609 (GRCm39) |
R113G |
probably damaging |
Het |
| Garre1 |
T |
A |
7: 33,957,461 (GRCm39) |
I59L |
probably benign |
Het |
| Gm10684 |
A |
G |
9: 45,021,511 (GRCm39) |
|
probably benign |
Het |
| Gm12185 |
T |
C |
11: 48,806,231 (GRCm39) |
E320G |
probably benign |
Het |
| Gm14412 |
G |
T |
2: 177,007,269 (GRCm39) |
H209N |
probably damaging |
Het |
| Gm14412 |
A |
C |
2: 177,007,630 (GRCm39) |
S88R |
probably benign |
Het |
| Grhl1 |
T |
A |
12: 24,658,555 (GRCm39) |
L400Q |
probably damaging |
Het |
| Havcr1 |
T |
A |
11: 46,664,511 (GRCm39) |
Y216* |
probably null |
Het |
| Hephl1 |
A |
C |
9: 14,985,420 (GRCm39) |
Y745* |
probably null |
Het |
| Hmcn2 |
T |
G |
2: 31,301,922 (GRCm39) |
|
probably null |
Het |
| Hs3st6 |
A |
G |
17: 24,977,110 (GRCm39) |
K197E |
possibly damaging |
Het |
| Ifi214 |
C |
T |
1: 173,357,077 (GRCm39) |
V9I |
probably benign |
Het |
| Jakmip2 |
T |
C |
18: 43,700,209 (GRCm39) |
T450A |
probably benign |
Het |
| Lrp4 |
T |
A |
2: 91,328,753 (GRCm39) |
V1551D |
possibly damaging |
Het |
| Macf1 |
A |
T |
4: 123,351,634 (GRCm39) |
H1634Q |
possibly damaging |
Het |
| Mcpt8 |
T |
A |
14: 56,321,291 (GRCm39) |
I58F |
probably benign |
Het |
| Mga |
T |
A |
2: 119,757,075 (GRCm39) |
H1018Q |
possibly damaging |
Het |
| Myo10 |
T |
A |
15: 25,801,308 (GRCm39) |
V1499E |
probably damaging |
Het |
| Myom2 |
G |
T |
8: 15,131,023 (GRCm39) |
D320Y |
probably damaging |
Het |
| Or11g7 |
T |
A |
14: 50,691,295 (GRCm39) |
M262K |
probably damaging |
Het |
| Or13a27 |
T |
C |
7: 139,925,378 (GRCm39) |
I175V |
probably benign |
Het |
| Or2r11 |
C |
T |
6: 42,437,360 (GRCm39) |
V198M |
probably benign |
Het |
| Or2t26 |
A |
C |
11: 49,039,101 (GRCm39) |
N6H |
possibly damaging |
Het |
| Or4c115 |
G |
A |
2: 88,927,888 (GRCm39) |
P128S |
probably damaging |
Het |
| Or5d47 |
A |
T |
2: 87,804,403 (GRCm39) |
V202D |
possibly damaging |
Het |
| Pabpc4 |
G |
T |
4: 123,182,861 (GRCm39) |
R166L |
possibly damaging |
Het |
| Pcdhb8 |
A |
G |
18: 37,489,015 (GRCm39) |
E231G |
possibly damaging |
Het |
| Pomgnt2 |
A |
T |
9: 121,811,257 (GRCm39) |
I508N |
possibly damaging |
Het |
| Ppp2r5e |
C |
G |
12: 75,516,341 (GRCm39) |
A239P |
probably damaging |
Het |
| Prdm15 |
G |
T |
16: 97,638,885 (GRCm39) |
D58E |
probably benign |
Het |
| Rgl2 |
A |
G |
17: 34,151,122 (GRCm39) |
T117A |
probably benign |
Het |
| Rp1 |
A |
G |
1: 4,418,943 (GRCm39) |
I723T |
probably damaging |
Het |
| Serpina3g |
A |
G |
12: 104,207,536 (GRCm39) |
E233G |
probably damaging |
Het |
| Skint6 |
T |
A |
4: 112,749,187 (GRCm39) |
S798C |
probably benign |
Het |
| Slc35f1 |
T |
C |
10: 52,898,000 (GRCm39) |
L137P |
possibly damaging |
Het |
| Slc6a20a |
T |
C |
9: 123,485,373 (GRCm39) |
N246S |
probably damaging |
Het |
| Slc7a2 |
T |
C |
8: 41,369,534 (GRCm39) |
L663S |
probably benign |
Het |
| Slco1a4 |
A |
G |
6: 141,761,173 (GRCm39) |
|
probably null |
Het |
| Slit2 |
A |
G |
5: 48,439,330 (GRCm39) |
T41A |
probably damaging |
Het |
| Smc2 |
T |
C |
4: 52,450,863 (GRCm39) |
I227T |
probably damaging |
Het |
| Smg1 |
A |
G |
7: 117,753,422 (GRCm39) |
|
probably benign |
Het |
| Ssu2 |
A |
T |
6: 112,361,388 (GRCm39) |
L23M |
probably benign |
Het |
| Syne2 |
A |
G |
12: 76,141,053 (GRCm39) |
|
probably null |
Het |
| Tekt1 |
T |
C |
11: 72,242,761 (GRCm39) |
T249A |
probably benign |
Het |
| Tfr2 |
T |
C |
5: 137,569,954 (GRCm39) |
V120A |
probably benign |
Het |
| Thsd7b |
C |
T |
1: 129,605,846 (GRCm39) |
P529L |
probably damaging |
Het |
| Tll1 |
C |
T |
8: 64,478,141 (GRCm39) |
D871N |
probably damaging |
Het |
| Tlr11 |
A |
C |
14: 50,598,664 (GRCm39) |
I217L |
probably benign |
Het |
| Tmem87b |
T |
A |
2: 128,673,479 (GRCm39) |
V241D |
probably damaging |
Het |
| Tshz2 |
T |
A |
2: 169,727,465 (GRCm39) |
I218N |
possibly damaging |
Het |
| Vmn1r18 |
A |
T |
6: 57,367,026 (GRCm39) |
I176N |
possibly damaging |
Het |
| Vmn2r68 |
T |
A |
7: 84,883,260 (GRCm39) |
H164L |
probably benign |
Het |
| Vmn2r74 |
T |
C |
7: 85,601,650 (GRCm39) |
T663A |
probably benign |
Het |
| Vmn2r8 |
T |
C |
5: 108,945,436 (GRCm39) |
T724A |
probably benign |
Het |
| Wdr11 |
T |
C |
7: 129,206,954 (GRCm39) |
V289A |
possibly damaging |
Het |
| Zfp62 |
T |
A |
11: 49,107,047 (GRCm39) |
D379E |
probably damaging |
Het |
| Zfp78 |
C |
T |
7: 6,381,897 (GRCm39) |
P316S |
probably damaging |
Het |
| Zfyve27 |
T |
G |
19: 42,159,987 (GRCm39) |
M1R |
probably null |
Het |
| Zkscan8 |
G |
A |
13: 21,709,325 (GRCm39) |
P191L |
probably damaging |
Het |
|
| Other mutations in Apc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01069:Apc2
|
APN |
10 |
80,147,820 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01154:Apc2
|
APN |
10 |
80,148,903 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01411:Apc2
|
APN |
10 |
80,150,912 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01598:Apc2
|
APN |
10 |
80,148,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01621:Apc2
|
APN |
10 |
80,142,035 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01720:Apc2
|
APN |
10 |
80,150,333 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01837:Apc2
|
APN |
10 |
80,150,492 (GRCm39) |
missense |
probably benign |
0.24 |
|
IGL01933:Apc2
|
APN |
10 |
80,147,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02243:Apc2
|
APN |
10 |
80,138,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02292:Apc2
|
APN |
10 |
80,138,258 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
IGL02956:Apc2
|
APN |
10 |
80,142,209 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03081:Apc2
|
APN |
10 |
80,148,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03172:Apc2
|
APN |
10 |
80,149,220 (GRCm39) |
missense |
probably damaging |
0.98 |
|
LCD18:Apc2
|
UTSW |
10 |
80,135,808 (GRCm39) |
intron |
probably benign |
|
|
R0278:Apc2
|
UTSW |
10 |
80,148,647 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0501:Apc2
|
UTSW |
10 |
80,150,958 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0594:Apc2
|
UTSW |
10 |
80,142,090 (GRCm39) |
nonsense |
probably null |
|
|
R0607:Apc2
|
UTSW |
10 |
80,149,935 (GRCm39) |
missense |
probably benign |
|
|
R0624:Apc2
|
UTSW |
10 |
80,150,417 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0633:Apc2
|
UTSW |
10 |
80,143,289 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0638:Apc2
|
UTSW |
10 |
80,140,801 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0647:Apc2
|
UTSW |
10 |
80,140,762 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0830:Apc2
|
UTSW |
10 |
80,151,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1071:Apc2
|
UTSW |
10 |
80,147,336 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1221:Apc2
|
UTSW |
10 |
80,142,214 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1432:Apc2
|
UTSW |
10 |
80,148,183 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1579:Apc2
|
UTSW |
10 |
80,147,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1654:Apc2
|
UTSW |
10 |
80,137,676 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1700:Apc2
|
UTSW |
10 |
80,148,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1774:Apc2
|
UTSW |
10 |
80,144,964 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1864:Apc2
|
UTSW |
10 |
80,149,482 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1915:Apc2
|
UTSW |
10 |
80,151,701 (GRCm39) |
missense |
probably benign |
|
|
R1999:Apc2
|
UTSW |
10 |
80,144,994 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2050:Apc2
|
UTSW |
10 |
80,143,443 (GRCm39) |
splice site |
probably null |
|
|
R2219:Apc2
|
UTSW |
10 |
80,144,943 (GRCm39) |
missense |
probably benign |
0.41 |
|
R2393:Apc2
|
UTSW |
10 |
80,148,903 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R3862:Apc2
|
UTSW |
10 |
80,143,393 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R3900:Apc2
|
UTSW |
10 |
80,131,806 (GRCm39) |
splice site |
probably null |
|
|
R3901:Apc2
|
UTSW |
10 |
80,150,922 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3952:Apc2
|
UTSW |
10 |
80,150,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4009:Apc2
|
UTSW |
10 |
80,149,426 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4090:Apc2
|
UTSW |
10 |
80,141,378 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4695:Apc2
|
UTSW |
10 |
80,146,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4754:Apc2
|
UTSW |
10 |
80,150,192 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4807:Apc2
|
UTSW |
10 |
80,150,196 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4886:Apc2
|
UTSW |
10 |
80,150,047 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4964:Apc2
|
UTSW |
10 |
80,149,841 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5056:Apc2
|
UTSW |
10 |
80,137,148 (GRCm39) |
missense |
probably benign |
|
|
R5057:Apc2
|
UTSW |
10 |
80,144,903 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5165:Apc2
|
UTSW |
10 |
80,151,684 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5241:Apc2
|
UTSW |
10 |
80,148,068 (GRCm39) |
missense |
probably benign |
|
|
R5649:Apc2
|
UTSW |
10 |
80,149,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5924:Apc2
|
UTSW |
10 |
80,147,984 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6124:Apc2
|
UTSW |
10 |
80,142,185 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6218:Apc2
|
UTSW |
10 |
80,142,254 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6376:Apc2
|
UTSW |
10 |
80,148,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6490:Apc2
|
UTSW |
10 |
80,149,757 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6572:Apc2
|
UTSW |
10 |
80,147,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6620:Apc2
|
UTSW |
10 |
80,149,401 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7171:Apc2
|
UTSW |
10 |
80,151,170 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R7180:Apc2
|
UTSW |
10 |
80,146,990 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7326:Apc2
|
UTSW |
10 |
80,147,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7340:Apc2
|
UTSW |
10 |
80,149,316 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7378:Apc2
|
UTSW |
10 |
80,147,228 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7384:Apc2
|
UTSW |
10 |
80,148,458 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7431:Apc2
|
UTSW |
10 |
80,138,017 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7543:Apc2
|
UTSW |
10 |
80,150,720 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7743:Apc2
|
UTSW |
10 |
80,140,749 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7759:Apc2
|
UTSW |
10 |
80,147,030 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8244:Apc2
|
UTSW |
10 |
80,151,166 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8327:Apc2
|
UTSW |
10 |
80,137,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8489:Apc2
|
UTSW |
10 |
80,143,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8494:Apc2
|
UTSW |
10 |
80,150,313 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8669:Apc2
|
UTSW |
10 |
80,149,491 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8773:Apc2
|
UTSW |
10 |
80,142,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8920:Apc2
|
UTSW |
10 |
80,149,934 (GRCm39) |
missense |
probably benign |
|
|
R9178:Apc2
|
UTSW |
10 |
80,150,235 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9224:Apc2
|
UTSW |
10 |
80,150,111 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9357:Apc2
|
UTSW |
10 |
80,146,872 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9394:Apc2
|
UTSW |
10 |
80,145,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9666:Apc2
|
UTSW |
10 |
80,147,183 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R9689:Apc2
|
UTSW |
10 |
80,150,733 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0018:Apc2
|
UTSW |
10 |
80,148,098 (GRCm39) |
missense |
probably benign |
0.02 |
|
Z1177:Apc2
|
UTSW |
10 |
80,147,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAAGATCTCTGAGCTGGCAG -3'
(R):5'- AAAGTCAGCTGTCTTCGGAAG -3'
Sequencing Primer
(F):5'- TGGCAGCTTTGCGCCAC -3'
(R):5'- AGCTGTCTTCGGAAGCCTGAG -3'
|
| Posted On |
2014-06-30 |
Incidental Mutation