Incidental Mutation 'R1912:Igsf10'
| ID |
210355 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Igsf10
|
| Ensembl Gene |
ENSMUSG00000036334 |
| Gene Name |
immunoglobulin superfamily, member 10 |
| Synonyms |
6530405F15Rik, CMF608, Adlican2 |
| MMRRC Submission |
039930-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.193)
|
| Stock # |
R1912 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
59224156-59251815 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 59236993 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Proline
at position 1063
(T1063P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000141391
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039419]
[ENSMUST00000193455]
[ENSMUST00000194546]
|
| AlphaFold |
Q3V1M1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000039419
AA Change: T1063P
PolyPhen 2
Score 0.403 (Sensitivity: 0.89; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000037246
Gene: ENSMUSG00000036334
AA Change: T1063P
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
LRRNT
|
28 |
61 |
3.24e-4 |
SMART |
|
LRR
|
57 |
79 |
9.24e1 |
SMART |
|
LRR
|
80 |
103 |
2.02e-1 |
SMART |
|
LRR
|
104 |
127 |
7.16e0 |
SMART |
|
LRR_TYP
|
128 |
151 |
1.2e-3 |
SMART |
|
LRR
|
152 |
175 |
1.25e-1 |
SMART |
|
LRR
|
188 |
207 |
2.33e2 |
SMART |
|
LRRCT
|
219 |
280 |
4.19e-4 |
SMART |
|
IGc2
|
488 |
558 |
2.34e-4 |
SMART |
|
IGc2
|
586 |
652 |
7.88e-11 |
SMART |
|
low complexity region
|
917 |
930 |
N/A |
INTRINSIC |
|
low complexity region
|
1175 |
1185 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1263 |
N/A |
INTRINSIC |
|
low complexity region
|
1311 |
1321 |
N/A |
INTRINSIC |
|
low complexity region
|
1449 |
1465 |
N/A |
INTRINSIC |
|
IGc2
|
1632 |
1701 |
7.69e-14 |
SMART |
|
IGc2
|
1729 |
1798 |
5.07e-14 |
SMART |
|
IGc2
|
1826 |
1895 |
2.19e-9 |
SMART |
|
IGc2
|
1925 |
1994 |
4.59e-12 |
SMART |
|
IGc2
|
2022 |
2097 |
1.33e-8 |
SMART |
|
IGc2
|
2125 |
2191 |
2.96e-15 |
SMART |
|
IGc2
|
2223 |
2291 |
2.03e-4 |
SMART |
|
IGc2
|
2321 |
2389 |
9.99e-13 |
SMART |
|
IGc2
|
2416 |
2484 |
3.03e-12 |
SMART |
|
IGc2
|
2512 |
2583 |
7.76e-10 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193455
AA Change: T1063P
PolyPhen 2
Score 0.403 (Sensitivity: 0.89; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000141971
Gene: ENSMUSG00000036334
AA Change: T1063P
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
LRRNT
|
28 |
61 |
3.24e-4 |
SMART |
|
LRR
|
57 |
79 |
9.24e1 |
SMART |
|
LRR
|
80 |
103 |
2.02e-1 |
SMART |
|
LRR
|
104 |
127 |
7.16e0 |
SMART |
|
LRR_TYP
|
128 |
151 |
1.2e-3 |
SMART |
|
LRR
|
152 |
175 |
1.25e-1 |
SMART |
|
LRR
|
188 |
207 |
2.33e2 |
SMART |
|
LRRCT
|
219 |
280 |
4.19e-4 |
SMART |
|
IGc2
|
488 |
558 |
2.34e-4 |
SMART |
|
IGc2
|
586 |
652 |
7.88e-11 |
SMART |
|
low complexity region
|
917 |
930 |
N/A |
INTRINSIC |
|
low complexity region
|
1175 |
1185 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1263 |
N/A |
INTRINSIC |
|
low complexity region
|
1311 |
1321 |
N/A |
INTRINSIC |
|
low complexity region
|
1449 |
1465 |
N/A |
INTRINSIC |
|
IGc2
|
1632 |
1701 |
7.69e-14 |
SMART |
|
IGc2
|
1729 |
1798 |
5.07e-14 |
SMART |
|
IGc2
|
1826 |
1895 |
2.19e-9 |
SMART |
|
IGc2
|
1925 |
1994 |
4.59e-12 |
SMART |
|
IGc2
|
2022 |
2097 |
1.33e-8 |
SMART |
|
IGc2
|
2125 |
2191 |
2.96e-15 |
SMART |
|
IGc2
|
2223 |
2291 |
2.03e-4 |
SMART |
|
IGc2
|
2321 |
2389 |
9.99e-13 |
SMART |
|
IGc2
|
2416 |
2484 |
3.03e-12 |
SMART |
|
IGc2
|
2512 |
2583 |
7.76e-10 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000194546
AA Change: T1063P
PolyPhen 2
Score 0.403 (Sensitivity: 0.89; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000141391
Gene: ENSMUSG00000036334
AA Change: T1063P
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
LRRNT
|
28 |
61 |
3.24e-4 |
SMART |
|
LRR
|
57 |
79 |
9.24e1 |
SMART |
|
LRR
|
80 |
103 |
2.02e-1 |
SMART |
|
LRR
|
104 |
127 |
7.16e0 |
SMART |
|
LRR_TYP
|
128 |
151 |
1.2e-3 |
SMART |
|
LRR
|
152 |
175 |
1.25e-1 |
SMART |
|
LRR
|
188 |
207 |
2.33e2 |
SMART |
|
LRRCT
|
219 |
280 |
4.19e-4 |
SMART |
|
IGc2
|
488 |
558 |
2.34e-4 |
SMART |
|
IGc2
|
586 |
652 |
7.88e-11 |
SMART |
|
low complexity region
|
917 |
930 |
N/A |
INTRINSIC |
|
low complexity region
|
1175 |
1185 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1263 |
N/A |
INTRINSIC |
|
low complexity region
|
1311 |
1321 |
N/A |
INTRINSIC |
|
low complexity region
|
1449 |
1465 |
N/A |
INTRINSIC |
|
IGc2
|
1632 |
1701 |
7.69e-14 |
SMART |
|
IGc2
|
1729 |
1798 |
5.07e-14 |
SMART |
|
IGc2
|
1826 |
1895 |
2.19e-9 |
SMART |
|
IGc2
|
1925 |
1994 |
4.59e-12 |
SMART |
|
IGc2
|
2022 |
2097 |
1.33e-8 |
SMART |
|
IGc2
|
2125 |
2191 |
2.96e-15 |
SMART |
|
IGc2
|
2223 |
2291 |
2.03e-4 |
SMART |
|
IGc2
|
2321 |
2389 |
9.99e-13 |
SMART |
|
IGc2
|
2416 |
2484 |
3.03e-12 |
SMART |
|
IGc2
|
2512 |
2583 |
7.76e-10 |
SMART |
|
| Coding Region Coverage |
- 1x: 97.3%
- 3x: 96.8%
- 10x: 95.3%
- 20x: 92.8%
|
| Validation Efficiency |
|
| Allele List at MGI |
All alleles(2) : Targeted, other(2) |
| Other mutations in this stock |
Total: 122 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2900092C05Rik |
A |
G |
7: 12,288,582 (GRCm39) |
M132V |
probably benign |
Het |
| 4921524L21Rik |
T |
A |
18: 6,620,205 (GRCm39) |
I45N |
possibly damaging |
Het |
| Abcb6 |
A |
G |
1: 75,156,599 (GRCm39) |
V55A |
probably benign |
Het |
| Adam28 |
A |
T |
14: 68,881,780 (GRCm39) |
D105E |
probably benign |
Het |
| Ahnak |
T |
C |
19: 8,995,245 (GRCm39) |
S5510P |
probably damaging |
Het |
| Aldh3b1 |
T |
G |
19: 3,971,187 (GRCm39) |
D159A |
probably damaging |
Het |
| Alx1 |
A |
G |
10: 102,861,222 (GRCm39) |
L102P |
probably damaging |
Het |
| Ankrd50 |
C |
T |
3: 38,510,925 (GRCm39) |
V481I |
probably benign |
Het |
| Aox4 |
G |
T |
1: 58,303,561 (GRCm39) |
G1200W |
probably damaging |
Het |
| Arhgap45 |
A |
C |
10: 79,856,524 (GRCm39) |
D24A |
probably benign |
Het |
| Arhgef16 |
A |
T |
4: 154,364,780 (GRCm39) |
|
probably null |
Het |
| Asic4 |
A |
T |
1: 75,445,876 (GRCm39) |
Y235F |
possibly damaging |
Het |
| Asph |
T |
C |
4: 9,453,335 (GRCm39) |
E646G |
probably damaging |
Het |
| Atg4d |
A |
G |
9: 21,183,935 (GRCm39) |
D350G |
probably damaging |
Het |
| Auts2 |
T |
C |
5: 131,472,412 (GRCm39) |
T347A |
probably damaging |
Het |
| Bsnd |
A |
T |
4: 106,345,227 (GRCm39) |
L73* |
probably null |
Het |
| Cachd1 |
A |
T |
4: 100,810,366 (GRCm39) |
S323C |
probably damaging |
Het |
| Cacna1e |
A |
G |
1: 154,312,195 (GRCm39) |
I1290T |
probably damaging |
Het |
| Cdh8 |
T |
A |
8: 99,825,502 (GRCm39) |
N498Y |
probably damaging |
Het |
| Cdkn3 |
A |
G |
14: 47,007,291 (GRCm39) |
|
probably null |
Het |
| Celf2 |
A |
T |
2: 6,620,564 (GRCm39) |
M40K |
probably damaging |
Het |
| Cfap57 |
A |
C |
4: 118,472,207 (GRCm39) |
S57R |
probably damaging |
Het |
| Cfh |
A |
G |
1: 140,063,879 (GRCm39) |
|
probably null |
Het |
| Chdh |
A |
G |
14: 29,754,745 (GRCm39) |
S252G |
probably benign |
Het |
| Col8a1 |
T |
A |
16: 57,448,287 (GRCm39) |
I408F |
unknown |
Het |
| Corin |
C |
T |
5: 72,515,746 (GRCm39) |
C303Y |
probably damaging |
Het |
| Crlf2 |
C |
T |
5: 109,705,007 (GRCm39) |
C66Y |
possibly damaging |
Het |
| Csmd1 |
C |
T |
8: 16,284,012 (GRCm39) |
|
probably null |
Het |
| Cyp4f16 |
T |
C |
17: 32,764,018 (GRCm39) |
V270A |
probably damaging |
Het |
| Defa29 |
T |
A |
8: 21,816,028 (GRCm39) |
H113L |
possibly damaging |
Het |
| Dhx35 |
A |
T |
2: 158,684,227 (GRCm39) |
N501Y |
probably damaging |
Het |
| Dipk1b |
A |
G |
2: 26,522,716 (GRCm39) |
E55G |
probably damaging |
Het |
| Dst |
A |
G |
1: 34,330,931 (GRCm39) |
R4690G |
probably damaging |
Het |
| Elac2 |
T |
A |
11: 64,885,089 (GRCm39) |
D439E |
probably benign |
Het |
| Ercc6 |
A |
G |
14: 32,298,760 (GRCm39) |
R1383G |
probably damaging |
Het |
| Fat3 |
T |
A |
9: 15,881,284 (GRCm39) |
Y3196F |
probably damaging |
Het |
| Fbxw13 |
A |
T |
9: 109,010,611 (GRCm39) |
D342E |
probably benign |
Het |
| Fmod |
A |
G |
1: 133,968,458 (GRCm39) |
N166S |
possibly damaging |
Het |
| Folh1 |
A |
G |
7: 86,412,175 (GRCm39) |
S199P |
possibly damaging |
Het |
| Fv1 |
A |
G |
4: 147,954,235 (GRCm39) |
N267S |
possibly damaging |
Het |
| Fyn |
T |
C |
10: 39,402,828 (GRCm39) |
V200A |
possibly damaging |
Het |
| Gfus |
A |
T |
15: 75,797,498 (GRCm39) |
D278E |
possibly damaging |
Het |
| Ggnbp2 |
T |
C |
11: 84,753,122 (GRCm39) |
N39S |
probably benign |
Het |
| Gm10509 |
A |
T |
17: 21,909,831 (GRCm39) |
I53F |
possibly damaging |
Het |
| Gpr139 |
A |
T |
7: 118,744,102 (GRCm39) |
I161N |
possibly damaging |
Het |
| Grhl2 |
C |
T |
15: 37,358,651 (GRCm39) |
T148I |
probably damaging |
Het |
| Hmcn1 |
C |
A |
1: 150,480,633 (GRCm39) |
M4514I |
probably benign |
Het |
| Itgav |
A |
G |
2: 83,625,830 (GRCm39) |
Y792C |
possibly damaging |
Het |
| Itgb2l |
T |
C |
16: 96,228,135 (GRCm39) |
Q456R |
probably benign |
Het |
| Jph4 |
G |
A |
14: 55,345,818 (GRCm39) |
A613V |
probably benign |
Het |
| Kcna2 |
A |
G |
3: 107,012,717 (GRCm39) |
T433A |
probably benign |
Het |
| Kmt2e |
A |
G |
5: 23,697,393 (GRCm39) |
K97R |
probably benign |
Het |
| Krba1 |
C |
A |
6: 48,392,699 (GRCm39) |
A871E |
probably benign |
Het |
| Loxhd1 |
T |
C |
18: 77,427,833 (GRCm39) |
F468L |
probably benign |
Het |
| Lpin1 |
A |
G |
12: 16,596,728 (GRCm39) |
V713A |
probably damaging |
Het |
| Ltbp2 |
T |
A |
12: 84,832,637 (GRCm39) |
I67F |
probably damaging |
Het |
| Mdc1 |
G |
A |
17: 36,155,430 (GRCm39) |
R35H |
probably benign |
Het |
| Mdc1 |
A |
G |
17: 36,161,703 (GRCm39) |
D872G |
probably benign |
Het |
| Mgam |
C |
T |
6: 40,741,119 (GRCm39) |
Q959* |
probably null |
Het |
| Mttp |
T |
A |
3: 137,821,788 (GRCm39) |
T260S |
probably benign |
Het |
| Naalad2 |
A |
T |
9: 18,287,831 (GRCm39) |
D266E |
probably benign |
Het |
| Nans |
T |
A |
4: 46,500,162 (GRCm39) |
L182H |
probably damaging |
Het |
| Nbas |
T |
A |
12: 13,616,145 (GRCm39) |
C2228S |
probably benign |
Het |
| Nfix |
A |
T |
8: 85,448,306 (GRCm39) |
V407E |
probably damaging |
Het |
| Nktr |
T |
A |
9: 121,579,306 (GRCm39) |
|
probably benign |
Het |
| Nlrp10 |
G |
A |
7: 108,524,602 (GRCm39) |
R293* |
probably null |
Het |
| Nrxn3 |
T |
C |
12: 88,762,112 (GRCm39) |
F53S |
probably damaging |
Het |
| Or11h4 |
G |
A |
14: 50,974,235 (GRCm39) |
P128L |
probably damaging |
Het |
| Or12e7 |
T |
C |
2: 87,287,727 (GRCm39) |
S73P |
probably damaging |
Het |
| Or1e21 |
A |
T |
11: 73,344,820 (GRCm39) |
F73I |
probably damaging |
Het |
| Or2f2 |
T |
C |
6: 42,767,411 (GRCm39) |
I146T |
probably benign |
Het |
| Or3a1c |
T |
C |
11: 74,046,711 (GRCm39) |
C244R |
probably damaging |
Het |
| Or5ak24 |
T |
A |
2: 85,260,604 (GRCm39) |
N190Y |
probably damaging |
Het |
| Or5p68 |
A |
G |
7: 107,946,014 (GRCm39) |
L58P |
probably damaging |
Het |
| Or6d12 |
A |
G |
6: 116,492,950 (GRCm39) |
T71A |
probably benign |
Het |
| Oxld1 |
A |
G |
11: 120,347,732 (GRCm39) |
V155A |
probably damaging |
Het |
| Pamr1 |
T |
A |
2: 102,472,645 (GRCm39) |
F648Y |
probably damaging |
Het |
| Parg |
T |
C |
14: 31,932,497 (GRCm39) |
W446R |
probably damaging |
Het |
| Pate13 |
A |
T |
9: 35,819,915 (GRCm39) |
T23S |
probably benign |
Het |
| Phf3 |
A |
T |
1: 30,843,426 (GRCm39) |
H1844Q |
probably damaging |
Het |
| Phf7 |
T |
C |
14: 30,962,281 (GRCm39) |
I175V |
possibly damaging |
Het |
| Pibf1 |
G |
A |
14: 99,425,245 (GRCm39) |
|
probably null |
Het |
| Plcxd1 |
A |
G |
5: 110,251,308 (GRCm39) |
I295V |
probably benign |
Het |
| Pole2 |
A |
C |
12: 69,256,764 (GRCm39) |
Y254D |
probably damaging |
Het |
| Ppm1e |
T |
A |
11: 87,135,196 (GRCm39) |
I225F |
probably benign |
Het |
| Pttg1ip2 |
C |
A |
5: 5,502,019 (GRCm39) |
W144C |
probably benign |
Het |
| Rem1 |
G |
A |
2: 152,476,455 (GRCm39) |
V238M |
probably damaging |
Het |
| Resf1 |
T |
A |
6: 149,230,342 (GRCm39) |
D1129E |
possibly damaging |
Het |
| Rnase2b |
T |
G |
14: 51,400,357 (GRCm39) |
V146G |
probably damaging |
Het |
| Rnf169 |
G |
A |
7: 99,575,461 (GRCm39) |
T378I |
probably damaging |
Het |
| Rpf2 |
A |
G |
10: 40,112,197 (GRCm39) |
F80L |
probably benign |
Het |
| Sec11c |
T |
A |
18: 65,947,945 (GRCm39) |
D128E |
probably damaging |
Het |
| Septin12 |
A |
G |
16: 4,806,417 (GRCm39) |
V248A |
probably damaging |
Het |
| Serinc1 |
T |
C |
10: 57,401,547 (GRCm39) |
N82S |
probably benign |
Het |
| Serpina9 |
A |
C |
12: 103,967,508 (GRCm39) |
W296G |
probably damaging |
Het |
| Sgo2b |
A |
C |
8: 64,384,503 (GRCm39) |
D164E |
probably damaging |
Het |
| Slc15a3 |
A |
G |
19: 10,825,977 (GRCm39) |
N223D |
probably damaging |
Het |
| Slc44a3 |
A |
G |
3: 121,325,815 (GRCm39) |
Y12H |
probably benign |
Het |
| Slco3a1 |
A |
G |
7: 74,154,359 (GRCm39) |
F42S |
probably damaging |
Het |
| Snrnp40 |
C |
G |
4: 130,271,836 (GRCm39) |
|
probably null |
Het |
| Snx7 |
A |
T |
3: 117,623,317 (GRCm39) |
|
probably null |
Het |
| Sorl1 |
A |
T |
9: 41,993,246 (GRCm39) |
D259E |
probably damaging |
Het |
| Stpg2 |
G |
A |
3: 139,228,742 (GRCm39) |
|
probably null |
Het |
| Strn |
T |
A |
17: 78,991,824 (GRCm39) |
Y165F |
probably damaging |
Het |
| Sval2 |
T |
A |
6: 41,841,254 (GRCm39) |
*106R |
probably null |
Het |
| Tcaf3 |
A |
G |
6: 42,573,622 (GRCm39) |
S197P |
possibly damaging |
Het |
| Tespa1 |
C |
A |
10: 130,190,592 (GRCm39) |
T73N |
probably benign |
Het |
| Tex10 |
C |
T |
4: 48,456,800 (GRCm39) |
R637Q |
probably benign |
Het |
| Thoc5 |
C |
A |
11: 4,865,561 (GRCm39) |
T380K |
probably benign |
Het |
| Tmprss7 |
T |
A |
16: 45,476,911 (GRCm39) |
R784* |
probably null |
Het |
| Trank1 |
A |
T |
9: 111,219,777 (GRCm39) |
L2171F |
probably benign |
Het |
| Trpm2 |
T |
G |
10: 77,781,710 (GRCm39) |
K303T |
probably benign |
Het |
| Unc80 |
G |
A |
1: 66,549,784 (GRCm39) |
V681M |
probably damaging |
Het |
| Usp40 |
A |
G |
1: 87,874,368 (GRCm39) |
F1131L |
probably benign |
Het |
| Vmn1r215 |
A |
T |
13: 23,260,673 (GRCm39) |
I238F |
possibly damaging |
Het |
| Vwa3a |
A |
T |
7: 120,394,850 (GRCm39) |
Y890F |
probably damaging |
Het |
| Zdhhc18 |
A |
G |
4: 133,341,171 (GRCm39) |
L234P |
probably damaging |
Het |
| Zfp109 |
A |
G |
7: 23,927,676 (GRCm39) |
S578P |
probably damaging |
Het |
| Zfp704 |
T |
C |
3: 9,674,418 (GRCm39) |
D121G |
unknown |
Het |
| Zgrf1 |
G |
T |
3: 127,356,786 (GRCm39) |
V671L |
probably benign |
Het |
| Zkscan8 |
A |
T |
13: 21,704,927 (GRCm39) |
C265* |
probably null |
Het |
| Zscan26 |
T |
C |
13: 21,629,310 (GRCm39) |
I398V |
possibly damaging |
Het |
|
| Other mutations in Igsf10 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00773:Igsf10
|
APN |
3 |
59,238,960 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL00790:Igsf10
|
APN |
3 |
59,226,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00916:Igsf10
|
APN |
3 |
59,238,548 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL00928:Igsf10
|
APN |
3 |
59,238,018 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01066:Igsf10
|
APN |
3 |
59,235,203 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01107:Igsf10
|
APN |
3 |
59,238,945 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01420:Igsf10
|
APN |
3 |
59,227,071 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01533:Igsf10
|
APN |
3 |
59,226,651 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01537:Igsf10
|
APN |
3 |
59,237,452 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01676:Igsf10
|
APN |
3 |
59,236,756 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL01676:Igsf10
|
APN |
3 |
59,233,432 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL01960:Igsf10
|
APN |
3 |
59,226,158 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02123:Igsf10
|
APN |
3 |
59,226,081 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02198:Igsf10
|
APN |
3 |
59,233,399 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02268:Igsf10
|
APN |
3 |
59,238,573 (GRCm39) |
nonsense |
probably null |
|
|
IGL02313:Igsf10
|
APN |
3 |
59,238,111 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02368:Igsf10
|
APN |
3 |
59,235,652 (GRCm39) |
missense |
probably benign |
|
|
IGL02494:Igsf10
|
APN |
3 |
59,235,427 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02549:Igsf10
|
APN |
3 |
59,236,662 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02616:Igsf10
|
APN |
3 |
59,226,027 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02957:Igsf10
|
APN |
3 |
59,238,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03067:Igsf10
|
APN |
3 |
59,226,339 (GRCm39) |
missense |
probably benign |
0.25 |
|
IGL03104:Igsf10
|
APN |
3 |
59,226,905 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03124:Igsf10
|
APN |
3 |
59,227,086 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03212:Igsf10
|
APN |
3 |
59,235,586 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL03347:Igsf10
|
APN |
3 |
59,239,321 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL03357:Igsf10
|
APN |
3 |
59,243,632 (GRCm39) |
missense |
probably benign |
0.35 |
|
F6893:Igsf10
|
UTSW |
3 |
59,238,481 (GRCm39) |
missense |
probably damaging |
1.00 |
|
FR4449:Igsf10
|
UTSW |
3 |
59,226,531 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT1430001:Igsf10
|
UTSW |
3 |
59,235,579 (GRCm39) |
missense |
probably benign |
0.06 |
|
PIT4402001:Igsf10
|
UTSW |
3 |
59,233,000 (GRCm39) |
missense |
probably benign |
0.00 |
|
PIT4810001:Igsf10
|
UTSW |
3 |
59,225,903 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0068:Igsf10
|
UTSW |
3 |
59,238,045 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0095:Igsf10
|
UTSW |
3 |
59,238,617 (GRCm39) |
nonsense |
probably null |
|
|
R0095:Igsf10
|
UTSW |
3 |
59,238,617 (GRCm39) |
nonsense |
probably null |
|
|
R0112:Igsf10
|
UTSW |
3 |
59,233,429 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0141:Igsf10
|
UTSW |
3 |
59,238,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0538:Igsf10
|
UTSW |
3 |
59,227,527 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0551:Igsf10
|
UTSW |
3 |
59,236,089 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0556:Igsf10
|
UTSW |
3 |
59,236,296 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0582:Igsf10
|
UTSW |
3 |
59,227,188 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0630:Igsf10
|
UTSW |
3 |
59,233,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0675:Igsf10
|
UTSW |
3 |
59,236,015 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0948:Igsf10
|
UTSW |
3 |
59,238,525 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1252:Igsf10
|
UTSW |
3 |
59,239,269 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1412:Igsf10
|
UTSW |
3 |
59,235,196 (GRCm39) |
splice site |
probably benign |
|
|
R1473:Igsf10
|
UTSW |
3 |
59,226,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1585:Igsf10
|
UTSW |
3 |
59,237,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1650:Igsf10
|
UTSW |
3 |
59,233,583 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1660:Igsf10
|
UTSW |
3 |
59,238,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1671:Igsf10
|
UTSW |
3 |
59,235,921 (GRCm39) |
nonsense |
probably null |
|
|
R1748:Igsf10
|
UTSW |
3 |
59,226,514 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1758:Igsf10
|
UTSW |
3 |
59,236,617 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1856:Igsf10
|
UTSW |
3 |
59,238,693 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R2148:Igsf10
|
UTSW |
3 |
59,243,998 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R2155:Igsf10
|
UTSW |
3 |
59,239,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2509:Igsf10
|
UTSW |
3 |
59,239,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2511:Igsf10
|
UTSW |
3 |
59,239,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2680:Igsf10
|
UTSW |
3 |
59,232,875 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2913:Igsf10
|
UTSW |
3 |
59,239,157 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R2927:Igsf10
|
UTSW |
3 |
59,236,848 (GRCm39) |
missense |
probably benign |
|
|
R3547:Igsf10
|
UTSW |
3 |
59,243,935 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3547:Igsf10
|
UTSW |
3 |
59,237,962 (GRCm39) |
missense |
probably benign |
0.02 |
|
R3548:Igsf10
|
UTSW |
3 |
59,243,935 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3620:Igsf10
|
UTSW |
3 |
59,243,752 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3732:Igsf10
|
UTSW |
3 |
59,233,135 (GRCm39) |
missense |
probably benign |
0.29 |
|
R3743:Igsf10
|
UTSW |
3 |
59,233,546 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R3973:Igsf10
|
UTSW |
3 |
59,239,345 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4005:Igsf10
|
UTSW |
3 |
59,235,981 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4184:Igsf10
|
UTSW |
3 |
59,227,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4302:Igsf10
|
UTSW |
3 |
59,226,171 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4404:Igsf10
|
UTSW |
3 |
59,236,972 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4575:Igsf10
|
UTSW |
3 |
59,237,521 (GRCm39) |
missense |
probably benign |
|
|
R4676:Igsf10
|
UTSW |
3 |
59,233,370 (GRCm39) |
missense |
probably benign |
0.23 |
|
R4700:Igsf10
|
UTSW |
3 |
59,227,751 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4765:Igsf10
|
UTSW |
3 |
59,237,126 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4986:Igsf10
|
UTSW |
3 |
59,236,027 (GRCm39) |
missense |
probably benign |
0.24 |
|
R5012:Igsf10
|
UTSW |
3 |
59,226,143 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5070:Igsf10
|
UTSW |
3 |
59,235,714 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5083:Igsf10
|
UTSW |
3 |
59,233,694 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5336:Igsf10
|
UTSW |
3 |
59,227,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5462:Igsf10
|
UTSW |
3 |
59,233,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5648:Igsf10
|
UTSW |
3 |
59,235,574 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5810:Igsf10
|
UTSW |
3 |
59,226,492 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5871:Igsf10
|
UTSW |
3 |
59,237,832 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5880:Igsf10
|
UTSW |
3 |
59,238,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5935:Igsf10
|
UTSW |
3 |
59,235,578 (GRCm39) |
missense |
probably benign |
0.12 |
|
R5979:Igsf10
|
UTSW |
3 |
59,243,894 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6145:Igsf10
|
UTSW |
3 |
59,239,077 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6222:Igsf10
|
UTSW |
3 |
59,226,336 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6224:Igsf10
|
UTSW |
3 |
59,232,931 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6264:Igsf10
|
UTSW |
3 |
59,235,928 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6283:Igsf10
|
UTSW |
3 |
59,226,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6336:Igsf10
|
UTSW |
3 |
59,237,760 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6490:Igsf10
|
UTSW |
3 |
59,236,992 (GRCm39) |
missense |
probably benign |
0.06 |
|
R6785:Igsf10
|
UTSW |
3 |
59,226,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6873:Igsf10
|
UTSW |
3 |
59,235,865 (GRCm39) |
missense |
probably benign |
|
|
R6889:Igsf10
|
UTSW |
3 |
59,239,354 (GRCm39) |
missense |
probably benign |
|
|
R7024:Igsf10
|
UTSW |
3 |
59,239,122 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7056:Igsf10
|
UTSW |
3 |
59,238,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7128:Igsf10
|
UTSW |
3 |
59,236,326 (GRCm39) |
missense |
probably benign |
|
|
R7251:Igsf10
|
UTSW |
3 |
59,226,875 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7313:Igsf10
|
UTSW |
3 |
59,236,837 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7340:Igsf10
|
UTSW |
3 |
59,233,189 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7447:Igsf10
|
UTSW |
3 |
59,239,222 (GRCm39) |
missense |
probably benign |
0.39 |
|
R7506:Igsf10
|
UTSW |
3 |
59,226,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7678:Igsf10
|
UTSW |
3 |
59,226,761 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7695:Igsf10
|
UTSW |
3 |
59,233,612 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7709:Igsf10
|
UTSW |
3 |
59,238,964 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7749:Igsf10
|
UTSW |
3 |
59,236,549 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7808:Igsf10
|
UTSW |
3 |
59,235,489 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7850:Igsf10
|
UTSW |
3 |
59,227,053 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7879:Igsf10
|
UTSW |
3 |
59,238,145 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7886:Igsf10
|
UTSW |
3 |
59,235,748 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7891:Igsf10
|
UTSW |
3 |
59,235,832 (GRCm39) |
nonsense |
probably null |
|
|
R7946:Igsf10
|
UTSW |
3 |
59,227,125 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7948:Igsf10
|
UTSW |
3 |
59,239,279 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8004:Igsf10
|
UTSW |
3 |
59,237,130 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8096:Igsf10
|
UTSW |
3 |
59,236,380 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8141:Igsf10
|
UTSW |
3 |
59,237,949 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8183:Igsf10
|
UTSW |
3 |
59,238,036 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8203:Igsf10
|
UTSW |
3 |
59,236,254 (GRCm39) |
missense |
probably benign |
0.11 |
|
R8325:Igsf10
|
UTSW |
3 |
59,225,954 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8350:Igsf10
|
UTSW |
3 |
59,238,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8387:Igsf10
|
UTSW |
3 |
59,236,564 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8488:Igsf10
|
UTSW |
3 |
59,227,431 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8697:Igsf10
|
UTSW |
3 |
59,226,308 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8786:Igsf10
|
UTSW |
3 |
59,238,063 (GRCm39) |
missense |
probably benign |
0.25 |
|
R8804:Igsf10
|
UTSW |
3 |
59,243,876 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8886:Igsf10
|
UTSW |
3 |
59,237,410 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8902:Igsf10
|
UTSW |
3 |
59,243,633 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8906:Igsf10
|
UTSW |
3 |
59,233,739 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8917:Igsf10
|
UTSW |
3 |
59,226,888 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R9051:Igsf10
|
UTSW |
3 |
59,236,668 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9178:Igsf10
|
UTSW |
3 |
59,233,480 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R9228:Igsf10
|
UTSW |
3 |
59,243,843 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9230:Igsf10
|
UTSW |
3 |
59,243,843 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9231:Igsf10
|
UTSW |
3 |
59,243,843 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9232:Igsf10
|
UTSW |
3 |
59,243,843 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9417:Igsf10
|
UTSW |
3 |
59,236,526 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9609:Igsf10
|
UTSW |
3 |
59,226,869 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9631:Igsf10
|
UTSW |
3 |
59,237,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9689:Igsf10
|
UTSW |
3 |
59,233,624 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9762:Igsf10
|
UTSW |
3 |
59,237,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9770:Igsf10
|
UTSW |
3 |
59,227,199 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9798:Igsf10
|
UTSW |
3 |
59,239,126 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Igsf10
|
UTSW |
3 |
59,237,359 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
Z1177:Igsf10
|
UTSW |
3 |
59,237,026 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CATGCTTGCTTCAGTGGGAG -3'
(R):5'- TCCAAGCGCCCTTCAGATTC -3'
Sequencing Primer
(F):5'- GTGGGTACTTTCACTTCTGAAATAG -3'
(R):5'- TTCAGATTCCCACACCACTG -3'
|
| Posted On |
2014-06-30 |
Incidental Mutation