Incidental Mutation 'R1875:Obsl1'
| ID |
211110 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Obsl1
|
| Ensembl Gene |
ENSMUSG00000026211 |
| Gene Name |
obscurin-like 1 |
| Synonyms |
|
| MMRRC Submission |
039897-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.269)
|
| Stock # |
R1875 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
75462469-75483134 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 75474877 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Cysteine
at position 841
(Y841C)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109197
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000113565]
[ENSMUST00000113567]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113565
AA Change: Y841C
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000109195
Gene: ENSMUSG00000026211
AA Change: Y841C
| Domain | Start | End | E-Value | Type |
|---|
|
IGc2
|
24 |
91 |
1.23e-12 |
SMART |
|
IGc2
|
140 |
216 |
2.33e-13 |
SMART |
|
IGc2
|
258 |
326 |
1.48e-6 |
SMART |
|
IG
|
347 |
427 |
9.49e-5 |
SMART |
|
IG
|
435 |
511 |
1.04e-1 |
SMART |
|
FN3
|
518 |
601 |
6.6e-2 |
SMART |
|
PDB:2E6Q|A
|
608 |
714 |
5e-57 |
PDB |
|
Blast:IG_like
|
622 |
711 |
2e-50 |
BLAST |
|
IG
|
723 |
804 |
3.79e-4 |
SMART |
|
IG
|
814 |
893 |
2.58e-6 |
SMART |
|
IGc2
|
911 |
977 |
1.12e-6 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113567
AA Change: Y841C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000109197
Gene: ENSMUSG00000026211
AA Change: Y841C
| Domain | Start | End | E-Value | Type |
|---|
|
IGc2
|
24 |
91 |
1.23e-12 |
SMART |
|
IGc2
|
140 |
216 |
2.33e-13 |
SMART |
|
IGc2
|
258 |
326 |
1.48e-6 |
SMART |
|
IG
|
347 |
427 |
9.49e-5 |
SMART |
|
IG
|
435 |
511 |
1.04e-1 |
SMART |
|
FN3
|
518 |
601 |
6.6e-2 |
SMART |
|
PDB:2E6Q|A
|
608 |
714 |
8e-57 |
PDB |
|
Blast:IG_like
|
622 |
711 |
3e-50 |
BLAST |
|
IG
|
723 |
804 |
3.79e-4 |
SMART |
|
IG
|
814 |
893 |
2.58e-6 |
SMART |
|
IGc2
|
911 |
977 |
1.12e-6 |
SMART |
|
IG
|
996 |
1075 |
1.27e-5 |
SMART |
|
IGc2
|
1094 |
1160 |
4.07e-4 |
SMART |
|
IGc2
|
1186 |
1252 |
9.49e-5 |
SMART |
|
IG
|
1274 |
1353 |
7.41e-7 |
SMART |
|
IG
|
1363 |
1444 |
1.15e-3 |
SMART |
|
IG
|
1454 |
1533 |
8.33e-1 |
SMART |
|
IGc2
|
1549 |
1615 |
8.72e-4 |
SMART |
|
IG
|
1633 |
1712 |
1e-3 |
SMART |
|
IG
|
1723 |
1802 |
3.82e-9 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000127507
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000129403
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000145306
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000155084
AA Change: Y646C
|
| SMART Domains |
Protein: ENSMUSP00000114553
Gene: ENSMUSG00000026211
AA Change: Y646C
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1g1ca_
|
2 |
32 |
1e-3 |
SMART |
|
IGc2
|
64 |
132 |
1.48e-6 |
SMART |
|
IG
|
153 |
233 |
9.49e-5 |
SMART |
|
IG
|
241 |
317 |
1.04e-1 |
SMART |
|
FN3
|
324 |
407 |
6.6e-2 |
SMART |
|
PDB:2E6Q|A
|
414 |
520 |
4e-57 |
PDB |
|
Blast:IG_like
|
428 |
517 |
2e-50 |
BLAST |
|
IG
|
529 |
610 |
3.79e-4 |
SMART |
|
IG
|
620 |
699 |
2.58e-6 |
SMART |
|
IGc2
|
717 |
783 |
1.12e-6 |
SMART |
|
IG
|
802 |
881 |
1.27e-5 |
SMART |
|
IGc2
|
900 |
966 |
4.07e-4 |
SMART |
|
IGc2
|
992 |
1058 |
9.49e-5 |
SMART |
|
IG
|
1080 |
1159 |
7.41e-7 |
SMART |
|
| Meta Mutation Damage Score |
0.5721 |
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.1%
- 20x: 92.1%
|
| Validation Efficiency |
98% (85/87) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca14 |
A |
T |
7: 119,847,190 (GRCm39) |
M685L |
possibly damaging |
Het |
| Abi3bp |
A |
G |
16: 56,394,862 (GRCm39) |
Y190C |
probably damaging |
Het |
| Adam26a |
C |
A |
8: 44,022,888 (GRCm39) |
V201L |
probably benign |
Het |
| Adamts20 |
G |
T |
15: 94,229,277 (GRCm39) |
D947E |
probably benign |
Het |
| Ankrd26 |
A |
G |
6: 118,517,410 (GRCm39) |
|
probably null |
Het |
| Apol11a |
C |
A |
15: 77,397,766 (GRCm39) |
T39N |
possibly damaging |
Het |
| Arhgef38 |
T |
A |
3: 132,839,501 (GRCm39) |
|
probably null |
Het |
| Armh4 |
T |
C |
14: 49,919,815 (GRCm39) |
D772G |
probably damaging |
Het |
| Atp11b |
T |
C |
3: 35,893,296 (GRCm39) |
L883P |
probably damaging |
Het |
| Btnl10 |
T |
A |
11: 58,814,586 (GRCm39) |
I422N |
probably damaging |
Het |
| C2cd3 |
A |
G |
7: 100,056,232 (GRCm39) |
K547E |
possibly damaging |
Het |
| Cdh2 |
T |
A |
18: 16,757,934 (GRCm39) |
L549F |
probably benign |
Het |
| Celsr3 |
T |
C |
9: 108,713,037 (GRCm39) |
V1825A |
probably benign |
Het |
| Cfap221 |
T |
C |
1: 119,881,389 (GRCm39) |
I358V |
probably benign |
Het |
| Cimap2 |
G |
A |
4: 106,470,453 (GRCm39) |
|
probably benign |
Het |
| Csmd1 |
T |
C |
8: 15,979,101 (GRCm39) |
K2828E |
probably damaging |
Het |
| Ddah2 |
T |
C |
17: 35,279,821 (GRCm39) |
F137S |
probably damaging |
Het |
| Ddx21 |
A |
G |
10: 62,429,847 (GRCm39) |
I299T |
probably damaging |
Het |
| Dnah7a |
A |
T |
1: 53,495,691 (GRCm39) |
|
probably benign |
Het |
| Elmod1 |
A |
G |
9: 53,843,151 (GRCm39) |
I9T |
probably benign |
Het |
| Epha2 |
A |
G |
4: 141,036,290 (GRCm39) |
E242G |
probably benign |
Het |
| Erbb3 |
T |
C |
10: 128,410,335 (GRCm39) |
H641R |
possibly damaging |
Het |
| Fbxl18 |
G |
A |
5: 142,871,978 (GRCm39) |
A419V |
probably damaging |
Het |
| Fli1 |
T |
C |
9: 32,335,209 (GRCm39) |
M408V |
probably benign |
Het |
| Fmo4 |
T |
C |
1: 162,631,187 (GRCm39) |
N260S |
possibly damaging |
Het |
| Fry |
A |
G |
5: 150,249,597 (GRCm39) |
E136G |
probably damaging |
Het |
| Gm10477 |
T |
A |
X: 55,570,127 (GRCm39) |
F9Y |
probably damaging |
Het |
| Gm8258 |
A |
G |
5: 104,924,320 (GRCm39) |
|
noncoding transcript |
Het |
| Gpr68 |
T |
A |
12: 100,845,049 (GRCm39) |
D165V |
probably damaging |
Het |
| Htt |
T |
A |
5: 34,951,456 (GRCm39) |
M139K |
probably benign |
Het |
| Jup |
A |
G |
11: 100,263,120 (GRCm39) |
|
probably null |
Het |
| Kifc5b |
G |
A |
17: 27,136,264 (GRCm39) |
|
probably null |
Het |
| Krba1 |
T |
A |
6: 48,390,983 (GRCm39) |
|
probably null |
Het |
| Lamp1 |
G |
A |
8: 13,217,257 (GRCm39) |
G89R |
probably damaging |
Het |
| Lrrc17 |
C |
T |
5: 21,765,650 (GRCm39) |
S44F |
possibly damaging |
Het |
| Mdga1 |
T |
C |
17: 30,071,581 (GRCm39) |
T347A |
probably damaging |
Het |
| Mical3 |
A |
T |
6: 121,019,025 (GRCm39) |
W66R |
probably damaging |
Het |
| Mpl |
A |
G |
4: 118,314,026 (GRCm39) |
Y73H |
probably benign |
Het |
| Mterf1b |
T |
A |
5: 4,247,364 (GRCm39) |
I335N |
possibly damaging |
Het |
| Mylk3 |
A |
G |
8: 86,079,494 (GRCm39) |
I388T |
probably damaging |
Het |
| Myo15a |
C |
T |
11: 60,398,354 (GRCm39) |
R2775W |
probably damaging |
Het |
| Myoz2 |
A |
T |
3: 122,819,765 (GRCm39) |
S65T |
probably damaging |
Het |
| Ndrg1 |
T |
C |
15: 66,802,940 (GRCm39) |
T137A |
possibly damaging |
Het |
| Neil3 |
G |
T |
8: 54,052,454 (GRCm39) |
N381K |
probably damaging |
Het |
| Or2b4 |
A |
G |
17: 38,115,996 (GRCm39) |
|
probably benign |
Het |
| Or6b6 |
G |
A |
7: 106,571,389 (GRCm39) |
S54F |
possibly damaging |
Het |
| Otogl |
T |
C |
10: 107,735,451 (GRCm39) |
D111G |
probably damaging |
Het |
| Parp10 |
T |
C |
15: 76,127,051 (GRCm39) |
E103G |
probably damaging |
Het |
| Pars2 |
T |
C |
4: 106,510,913 (GRCm39) |
F232L |
possibly damaging |
Het |
| Pcdh18 |
A |
T |
3: 49,709,154 (GRCm39) |
F720L |
probably damaging |
Het |
| Phf3 |
T |
C |
1: 30,869,704 (GRCm39) |
E448G |
possibly damaging |
Het |
| Pigc |
A |
G |
1: 161,798,516 (GRCm39) |
Y166C |
probably damaging |
Het |
| Pik3c2a |
A |
T |
7: 116,017,206 (GRCm39) |
S184T |
probably benign |
Het |
| Pkd1l1 |
A |
G |
11: 8,794,670 (GRCm39) |
|
probably benign |
Het |
| Plch2 |
G |
A |
4: 155,082,965 (GRCm39) |
S485F |
probably damaging |
Het |
| Plxnd1 |
G |
T |
6: 115,955,045 (GRCm39) |
|
probably null |
Het |
| Pnliprp2 |
G |
T |
19: 58,751,821 (GRCm39) |
V189L |
probably benign |
Het |
| Prl8a2 |
T |
C |
13: 27,535,037 (GRCm39) |
V103A |
probably benign |
Het |
| Psg23 |
G |
A |
7: 18,344,375 (GRCm39) |
T360I |
probably benign |
Het |
| Rad51c |
A |
T |
11: 87,279,469 (GRCm39) |
I323N |
probably damaging |
Het |
| Rsbn1l |
C |
T |
5: 21,156,696 (GRCm39) |
E30K |
probably benign |
Het |
| Serpina3c |
C |
A |
12: 104,118,145 (GRCm39) |
L64F |
probably damaging |
Het |
| Shroom1 |
A |
G |
11: 53,356,502 (GRCm39) |
D392G |
probably damaging |
Het |
| Slc26a5 |
T |
A |
5: 22,020,725 (GRCm39) |
I540L |
probably benign |
Het |
| Slc37a4 |
A |
G |
9: 44,312,808 (GRCm39) |
T321A |
probably damaging |
Het |
| Slc41a2 |
A |
G |
10: 83,091,949 (GRCm39) |
L438S |
probably damaging |
Het |
| Spef2 |
C |
T |
15: 9,584,194 (GRCm39) |
E1624K |
probably damaging |
Het |
| Spef2 |
C |
T |
15: 9,597,487 (GRCm39) |
G1390R |
possibly damaging |
Het |
| Spmap2l |
A |
T |
5: 77,202,431 (GRCm39) |
K284M |
probably benign |
Het |
| Synj2 |
G |
T |
17: 6,078,825 (GRCm39) |
A740S |
possibly damaging |
Het |
| Tigd4 |
A |
C |
3: 84,502,394 (GRCm39) |
D437A |
probably benign |
Het |
| Timm21 |
G |
C |
18: 84,967,387 (GRCm39) |
L130V |
probably damaging |
Het |
| Tmem106a |
CAGCTCAACACGACGGTA |
CAGCTCAACACGACGGTAAGCTCAACACGACGGTA |
11: 101,477,204 (GRCm39) |
|
probably benign |
Het |
| Tmem131l |
A |
T |
3: 83,812,383 (GRCm39) |
C1313* |
probably null |
Het |
| Tmem86b |
A |
T |
7: 4,632,698 (GRCm39) |
I47N |
possibly damaging |
Het |
| Tspan13 |
T |
C |
12: 36,070,550 (GRCm39) |
|
probably null |
Het |
| Vps54 |
A |
G |
11: 21,250,251 (GRCm39) |
T396A |
probably benign |
Het |
| Zfp106 |
A |
T |
2: 120,344,096 (GRCm39) |
|
probably null |
Het |
| Zfp668 |
T |
C |
7: 127,465,654 (GRCm39) |
|
probably null |
Het |
| Zfp809 |
A |
T |
9: 22,150,027 (GRCm39) |
R175* |
probably null |
Het |
|
| Other mutations in Obsl1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00504:Obsl1
|
APN |
1 |
75,467,518 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01111:Obsl1
|
APN |
1 |
75,473,789 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
IGL01140:Obsl1
|
APN |
1 |
75,466,400 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02149:Obsl1
|
APN |
1 |
75,480,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02225:Obsl1
|
APN |
1 |
75,480,442 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02269:Obsl1
|
APN |
1 |
75,464,357 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02296:Obsl1
|
APN |
1 |
75,474,793 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02386:Obsl1
|
APN |
1 |
75,469,161 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02408:Obsl1
|
APN |
1 |
75,481,890 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02601:Obsl1
|
APN |
1 |
75,466,264 (GRCm39) |
missense |
probably benign |
|
|
IGL03053:Obsl1
|
APN |
1 |
75,469,723 (GRCm39) |
missense |
probably benign |
|
|
IGL03181:Obsl1
|
APN |
1 |
75,469,228 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03402:Obsl1
|
APN |
1 |
75,463,443 (GRCm39) |
missense |
probably benign |
0.00 |
|
Jude
|
UTSW |
1 |
75,474,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT1430001:Obsl1
|
UTSW |
1 |
75,482,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4382001:Obsl1
|
UTSW |
1 |
75,464,607 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0281:Obsl1
|
UTSW |
1 |
75,469,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1343:Obsl1
|
UTSW |
1 |
75,469,223 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1394:Obsl1
|
UTSW |
1 |
75,469,309 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1395:Obsl1
|
UTSW |
1 |
75,469,309 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1439:Obsl1
|
UTSW |
1 |
75,463,428 (GRCm39) |
nonsense |
probably null |
|
|
R1456:Obsl1
|
UTSW |
1 |
75,464,300 (GRCm39) |
nonsense |
probably null |
|
|
R1728:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1729:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1730:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1739:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1757:Obsl1
|
UTSW |
1 |
75,470,527 (GRCm39) |
missense |
probably benign |
|
|
R1762:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1783:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1784:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1785:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1851:Obsl1
|
UTSW |
1 |
75,469,537 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1864:Obsl1
|
UTSW |
1 |
75,469,753 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1873:Obsl1
|
UTSW |
1 |
75,474,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1980:Obsl1
|
UTSW |
1 |
75,482,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1985:Obsl1
|
UTSW |
1 |
75,482,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2049:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2069:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2122:Obsl1
|
UTSW |
1 |
75,470,527 (GRCm39) |
missense |
probably benign |
|
|
R2141:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2142:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2184:Obsl1
|
UTSW |
1 |
75,478,861 (GRCm39) |
missense |
probably benign |
0.26 |
|
R2267:Obsl1
|
UTSW |
1 |
75,482,342 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2883:Obsl1
|
UTSW |
1 |
75,473,155 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R3079:Obsl1
|
UTSW |
1 |
75,467,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3749:Obsl1
|
UTSW |
1 |
75,474,890 (GRCm39) |
missense |
probably benign |
|
|
R4002:Obsl1
|
UTSW |
1 |
75,476,743 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4365:Obsl1
|
UTSW |
1 |
75,464,693 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4366:Obsl1
|
UTSW |
1 |
75,464,693 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4414:Obsl1
|
UTSW |
1 |
75,467,546 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4700:Obsl1
|
UTSW |
1 |
75,480,085 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4799:Obsl1
|
UTSW |
1 |
75,466,145 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5081:Obsl1
|
UTSW |
1 |
75,464,607 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R5389:Obsl1
|
UTSW |
1 |
75,479,905 (GRCm39) |
intron |
probably benign |
|
|
R5757:Obsl1
|
UTSW |
1 |
75,469,699 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5890:Obsl1
|
UTSW |
1 |
75,470,503 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5946:Obsl1
|
UTSW |
1 |
75,467,851 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6005:Obsl1
|
UTSW |
1 |
75,468,859 (GRCm39) |
splice site |
probably null |
|
|
R6118:Obsl1
|
UTSW |
1 |
75,468,722 (GRCm39) |
intron |
probably benign |
|
|
R6154:Obsl1
|
UTSW |
1 |
75,476,788 (GRCm39) |
missense |
probably benign |
0.19 |
|
R6317:Obsl1
|
UTSW |
1 |
75,466,273 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R6379:Obsl1
|
UTSW |
1 |
75,479,787 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6387:Obsl1
|
UTSW |
1 |
75,468,006 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7084:Obsl1
|
UTSW |
1 |
75,464,394 (GRCm39) |
missense |
probably benign |
|
|
R7123:Obsl1
|
UTSW |
1 |
75,466,313 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7202:Obsl1
|
UTSW |
1 |
75,466,360 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7291:Obsl1
|
UTSW |
1 |
75,466,161 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7305:Obsl1
|
UTSW |
1 |
75,470,590 (GRCm39) |
nonsense |
probably null |
|
|
R7366:Obsl1
|
UTSW |
1 |
75,479,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7402:Obsl1
|
UTSW |
1 |
75,464,348 (GRCm39) |
missense |
probably benign |
|
|
R7474:Obsl1
|
UTSW |
1 |
75,474,828 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7611:Obsl1
|
UTSW |
1 |
75,482,024 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7672:Obsl1
|
UTSW |
1 |
75,469,365 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7715:Obsl1
|
UTSW |
1 |
75,478,680 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7762:Obsl1
|
UTSW |
1 |
75,480,167 (GRCm39) |
missense |
probably benign |
|
|
R8005:Obsl1
|
UTSW |
1 |
75,482,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8012:Obsl1
|
UTSW |
1 |
75,469,317 (GRCm39) |
missense |
probably benign |
0.12 |
|
R8379:Obsl1
|
UTSW |
1 |
75,480,501 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8381:Obsl1
|
UTSW |
1 |
75,480,501 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8383:Obsl1
|
UTSW |
1 |
75,480,501 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8396:Obsl1
|
UTSW |
1 |
75,480,350 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8465:Obsl1
|
UTSW |
1 |
75,480,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8506:Obsl1
|
UTSW |
1 |
75,482,300 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8710:Obsl1
|
UTSW |
1 |
75,469,326 (GRCm39) |
missense |
probably benign |
|
|
R8877:Obsl1
|
UTSW |
1 |
75,473,167 (GRCm39) |
nonsense |
probably null |
|
|
R8903:Obsl1
|
UTSW |
1 |
75,463,917 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8913:Obsl1
|
UTSW |
1 |
75,467,892 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8924:Obsl1
|
UTSW |
1 |
75,482,841 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8955:Obsl1
|
UTSW |
1 |
75,480,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9008:Obsl1
|
UTSW |
1 |
75,482,027 (GRCm39) |
missense |
probably benign |
|
|
R9121:Obsl1
|
UTSW |
1 |
75,482,636 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9295:Obsl1
|
UTSW |
1 |
75,476,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9362:Obsl1
|
UTSW |
1 |
75,482,391 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9367:Obsl1
|
UTSW |
1 |
75,466,177 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9459:Obsl1
|
UTSW |
1 |
75,474,884 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9496:Obsl1
|
UTSW |
1 |
75,467,484 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9497:Obsl1
|
UTSW |
1 |
75,467,484 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9498:Obsl1
|
UTSW |
1 |
75,467,484 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9502:Obsl1
|
UTSW |
1 |
75,466,267 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9546:Obsl1
|
UTSW |
1 |
75,482,030 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9550:Obsl1
|
UTSW |
1 |
75,474,910 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9561:Obsl1
|
UTSW |
1 |
75,480,157 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9687:Obsl1
|
UTSW |
1 |
75,479,670 (GRCm39) |
missense |
probably damaging |
1.00 |
|
V8831:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
X0061:Obsl1
|
UTSW |
1 |
75,463,412 (GRCm39) |
missense |
probably benign |
|
|
Z1088:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
Z1176:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
Z1177:Obsl1
|
UTSW |
1 |
75,467,656 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
Z1177:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
Z1177:Obsl1
|
UTSW |
1 |
75,480,436 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGCTGCTCTCACCTGTGATG -3'
(R):5'- CAAACTCCTGCATGGCATGG -3'
Sequencing Primer
(F):5'- CTCACCTGTGATGGTAACTGTGAAG -3'
(R):5'- GCATGGCATGGCTTTAATTACC -3'
|
| Posted On |
2014-06-30 |
Incidental Mutation