Incidental Mutation 'R0403:Ddx60'
| ID |
212536 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ddx60
|
| Ensembl Gene |
ENSMUSG00000037921 |
| Gene Name |
DExD/H box helicase 60 |
| Synonyms |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| MMRRC Submission |
038608-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.215)
|
| Stock # |
R0403 (G1)
|
| Quality Score |
65 |
|
Status
|
Validated
|
| Chromosome |
8 |
| Chromosomal Location |
62381121-62490735 bp(+) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
A to G
at 62447575 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000091197
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000070631]
[ENSMUST00000093485]
|
| AlphaFold |
E9PZQ1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000070631
|
| SMART Domains |
Protein: ENSMUSP00000070741
Gene: ENSMUSG00000037921
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
99 |
110 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
376 |
N/A |
INTRINSIC |
|
DEXDc
|
758 |
949 |
1.05e-15 |
SMART |
|
Blast:DEXDc
|
1007 |
1132 |
4e-24 |
BLAST |
|
HELICc
|
1245 |
1328 |
4.35e-13 |
SMART |
|
low complexity region
|
1362 |
1373 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
1503 |
1584 |
1e-20 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000093485
|
| SMART Domains |
Protein: ENSMUSP00000091197
Gene: ENSMUSG00000037921
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
99 |
110 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
376 |
N/A |
INTRINSIC |
|
DEXDc
|
759 |
950 |
1.05e-15 |
SMART |
|
Blast:DEXDc
|
1008 |
1133 |
4e-24 |
BLAST |
|
HELICc
|
1246 |
1329 |
4.35e-13 |
SMART |
|
low complexity region
|
1363 |
1374 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
1504 |
1585 |
1e-20 |
BLAST |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 98.0%
- 3x: 96.8%
- 10x: 93.2%
- 20x: 83.7%
|
| Validation Efficiency |
97% (110/113) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal immunity to several viruses (IAV, EMCV, SINV) but increased susceptibility to VSV infection. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 105 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ace |
A |
G |
11: 105,864,706 (GRCm39) |
|
probably null |
Het |
| Adgrg3 |
C |
T |
8: 95,763,550 (GRCm39) |
L284F |
probably benign |
Het |
| Alkbh8 |
T |
A |
9: 3,385,469 (GRCm39) |
V587E |
probably damaging |
Het |
| Ap4b1 |
T |
A |
3: 103,728,712 (GRCm39) |
M590K |
probably benign |
Het |
| Ap4b1 |
T |
A |
3: 103,726,155 (GRCm39) |
C244S |
probably damaging |
Het |
| Arhgap15 |
C |
T |
2: 43,953,778 (GRCm39) |
T168I |
probably damaging |
Het |
| Atp8b1 |
A |
G |
18: 64,673,381 (GRCm39) |
V997A |
probably damaging |
Het |
| Atrn |
G |
A |
2: 130,748,779 (GRCm39) |
C100Y |
probably damaging |
Het |
| Baiap2l2 |
C |
A |
15: 79,155,416 (GRCm39) |
A151S |
probably benign |
Het |
| Baz2b |
A |
T |
2: 59,799,721 (GRCm39) |
D199E |
possibly damaging |
Het |
| Bmal2 |
T |
A |
6: 146,724,153 (GRCm39) |
H348Q |
probably damaging |
Het |
| Cblb |
A |
G |
16: 51,972,989 (GRCm39) |
D440G |
probably benign |
Het |
| Cdon |
T |
C |
9: 35,384,796 (GRCm39) |
V694A |
probably benign |
Het |
| Cep250 |
A |
T |
2: 155,834,269 (GRCm39) |
R2065W |
probably damaging |
Het |
| Ces2b |
G |
T |
8: 105,560,577 (GRCm39) |
A131S |
probably damaging |
Het |
| Chrna9 |
A |
T |
5: 66,125,235 (GRCm39) |
T59S |
possibly damaging |
Het |
| Cog3 |
T |
A |
14: 75,979,767 (GRCm39) |
|
probably benign |
Het |
| Cpa1 |
G |
A |
6: 30,641,856 (GRCm39) |
V227I |
probably benign |
Het |
| Cyp3a25 |
A |
T |
5: 145,935,323 (GRCm39) |
C98S |
probably damaging |
Het |
| D8Ertd738e |
C |
T |
8: 84,976,230 (GRCm39) |
|
probably null |
Het |
| Dhx16 |
T |
C |
17: 36,193,942 (GRCm39) |
|
probably null |
Het |
| Dnah9 |
T |
A |
11: 65,975,615 (GRCm39) |
Q1478L |
possibly damaging |
Het |
| Dock10 |
T |
C |
1: 80,501,787 (GRCm39) |
Y1434C |
possibly damaging |
Het |
| Enpp3 |
T |
A |
10: 24,680,334 (GRCm39) |
D325V |
probably damaging |
Het |
| Entpd6 |
C |
A |
2: 150,602,090 (GRCm39) |
T194K |
possibly damaging |
Het |
| Fat2 |
A |
T |
11: 55,161,175 (GRCm39) |
V3185E |
probably benign |
Het |
| Flrt1 |
A |
G |
19: 7,073,284 (GRCm39) |
L421P |
probably benign |
Het |
| Fmn2 |
A |
T |
1: 174,521,844 (GRCm39) |
Q1292L |
probably damaging |
Het |
| Fndc1 |
T |
C |
17: 7,972,555 (GRCm39) |
D1459G |
probably damaging |
Het |
| Fndc1 |
T |
C |
17: 7,994,420 (GRCm39) |
|
probably null |
Het |
| Fzr1 |
A |
G |
10: 81,205,202 (GRCm39) |
S265P |
possibly damaging |
Het |
| Gpr142 |
G |
A |
11: 114,696,855 (GRCm39) |
V134M |
probably damaging |
Het |
| Grid2ip |
G |
T |
5: 143,343,375 (GRCm39) |
V24L |
possibly damaging |
Het |
| Herc2 |
G |
A |
7: 55,809,165 (GRCm39) |
R2555H |
probably damaging |
Het |
| Hpdl |
A |
T |
4: 116,677,676 (GRCm39) |
Y262N |
possibly damaging |
Het |
| Htr3a |
A |
G |
9: 48,819,959 (GRCm39) |
V57A |
probably damaging |
Het |
| Igfbp7 |
T |
C |
5: 77,503,438 (GRCm39) |
I186V |
probably benign |
Het |
| Itga2b |
C |
T |
11: 102,358,152 (GRCm39) |
|
probably null |
Het |
| Itgae |
A |
C |
11: 73,014,009 (GRCm39) |
D736A |
possibly damaging |
Het |
| Itpkc |
T |
A |
7: 26,907,770 (GRCm39) |
M645L |
probably benign |
Het |
| Jchain |
T |
C |
5: 88,669,237 (GRCm39) |
R139G |
probably benign |
Het |
| Kif13a |
A |
G |
13: 46,944,877 (GRCm39) |
V908A |
probably damaging |
Het |
| Kif1b |
T |
A |
4: 149,266,424 (GRCm39) |
K389* |
probably null |
Het |
| Klhl12 |
T |
C |
1: 134,413,594 (GRCm39) |
Y360H |
possibly damaging |
Het |
| Knop1 |
G |
A |
7: 118,452,276 (GRCm39) |
R148W |
probably damaging |
Het |
| Lpar1 |
T |
A |
4: 58,487,191 (GRCm39) |
N27Y |
probably damaging |
Het |
| Lpar2 |
T |
A |
8: 70,276,802 (GRCm39) |
V197D |
probably damaging |
Het |
| Lrrc74a |
A |
G |
12: 86,787,753 (GRCm39) |
N128S |
probably damaging |
Het |
| Lum |
G |
T |
10: 97,407,905 (GRCm39) |
V337F |
probably benign |
Het |
| Mag |
T |
C |
7: 30,606,405 (GRCm39) |
D344G |
probably damaging |
Het |
| Maip1 |
G |
A |
1: 57,446,355 (GRCm39) |
A142T |
probably benign |
Het |
| Mlh3 |
A |
G |
12: 85,315,742 (GRCm39) |
V148A |
possibly damaging |
Het |
| Nav3 |
A |
G |
10: 109,602,964 (GRCm39) |
V1195A |
probably damaging |
Het |
| Ncor2 |
A |
G |
5: 125,110,401 (GRCm39) |
S868P |
possibly damaging |
Het |
| Nek1 |
A |
G |
8: 61,559,889 (GRCm39) |
E907G |
probably damaging |
Het |
| Nfam1 |
G |
A |
15: 82,900,580 (GRCm39) |
T134I |
probably benign |
Het |
| Nr0b2 |
T |
C |
4: 133,281,070 (GRCm39) |
V112A |
probably damaging |
Het |
| Nrp1 |
A |
G |
8: 129,184,450 (GRCm39) |
N365S |
probably damaging |
Het |
| Nrsn2 |
T |
C |
2: 152,211,710 (GRCm39) |
Y107C |
probably damaging |
Het |
| Ntng1 |
G |
A |
3: 109,841,927 (GRCm39) |
A282V |
probably damaging |
Het |
| Nxf1 |
T |
C |
19: 8,742,392 (GRCm39) |
I337T |
probably damaging |
Het |
| Obscn |
C |
T |
11: 58,967,366 (GRCm39) |
G479D |
probably damaging |
Het |
| Oprd1 |
T |
A |
4: 131,841,079 (GRCm39) |
D293V |
probably benign |
Het |
| Or13a17 |
T |
C |
7: 140,271,222 (GRCm39) |
S135P |
possibly damaging |
Het |
| P3h2 |
T |
G |
16: 25,788,700 (GRCm39) |
N586H |
possibly damaging |
Het |
| Pcid2 |
T |
C |
8: 13,135,367 (GRCm39) |
Y214C |
probably damaging |
Het |
| Pkd1l3 |
C |
G |
8: 110,350,281 (GRCm39) |
D375E |
possibly damaging |
Het |
| Pkd1l3 |
G |
A |
8: 110,350,295 (GRCm39) |
S380N |
probably benign |
Het |
| Ppic |
C |
A |
18: 53,544,143 (GRCm39) |
G81W |
probably damaging |
Het |
| Ppp2r1a |
C |
A |
17: 21,177,303 (GRCm39) |
P246T |
probably damaging |
Het |
| Ppp4r4 |
T |
G |
12: 103,550,361 (GRCm39) |
S46A |
probably benign |
Het |
| Pramel31 |
A |
G |
4: 144,089,216 (GRCm39) |
N178S |
probably benign |
Het |
| Prkce |
A |
G |
17: 86,476,081 (GRCm39) |
T21A |
probably damaging |
Het |
| Prkg2 |
T |
C |
5: 99,142,504 (GRCm39) |
E210G |
possibly damaging |
Het |
| Prss35 |
A |
G |
9: 86,638,090 (GRCm39) |
M287V |
probably damaging |
Het |
| Psd |
G |
A |
19: 46,309,411 (GRCm39) |
|
probably benign |
Het |
| Ptch2 |
A |
T |
4: 116,968,036 (GRCm39) |
K843* |
probably null |
Het |
| Rab44 |
C |
A |
17: 29,364,235 (GRCm39) |
T603K |
probably damaging |
Het |
| Rasal3 |
T |
A |
17: 32,611,764 (GRCm39) |
|
probably null |
Het |
| Rbbp6 |
A |
G |
7: 122,591,519 (GRCm39) |
T526A |
probably damaging |
Het |
| Ros1 |
A |
T |
10: 52,019,534 (GRCm39) |
|
probably benign |
Het |
| Sec24b |
T |
A |
3: 129,783,325 (GRCm39) |
L1104F |
possibly damaging |
Het |
| Sec24b |
A |
G |
3: 129,793,183 (GRCm39) |
S685P |
probably damaging |
Het |
| Sema6a |
G |
A |
18: 47,423,112 (GRCm39) |
|
probably null |
Het |
| Setmar |
A |
T |
6: 108,052,923 (GRCm39) |
H139L |
probably benign |
Het |
| Slc28a2b |
T |
C |
2: 122,352,335 (GRCm39) |
L364S |
probably damaging |
Het |
| Slc4a7 |
T |
C |
14: 14,766,808 (GRCm38) |
V710A |
probably benign |
Het |
| Smarcc1 |
T |
A |
9: 110,066,876 (GRCm39) |
|
probably null |
Het |
| Smchd1 |
G |
A |
17: 71,701,897 (GRCm39) |
L1032F |
probably damaging |
Het |
| Speg |
T |
C |
1: 75,407,428 (GRCm39) |
|
probably benign |
Het |
| Tasor2 |
A |
T |
13: 3,632,052 (GRCm39) |
Y816* |
probably null |
Het |
| Tcea1 |
C |
G |
1: 4,959,726 (GRCm39) |
R134G |
probably benign |
Het |
| Tchhl1 |
C |
T |
3: 93,378,336 (GRCm39) |
Q347* |
probably null |
Het |
| Tecrl |
A |
T |
5: 83,502,605 (GRCm39) |
|
probably benign |
Het |
| Tepsin |
T |
C |
11: 119,984,508 (GRCm39) |
|
probably benign |
Het |
| Tmem40 |
G |
A |
6: 115,710,946 (GRCm39) |
|
probably benign |
Het |
| Tpr |
G |
A |
1: 150,283,165 (GRCm39) |
|
probably benign |
Het |
| Ttll12 |
A |
T |
15: 83,464,859 (GRCm39) |
|
probably benign |
Het |
| Ttn |
T |
A |
2: 76,739,952 (GRCm39) |
D3529V |
probably benign |
Het |
| Usp34 |
T |
A |
11: 23,283,838 (GRCm39) |
H177Q |
possibly damaging |
Het |
| Vsig10 |
T |
A |
5: 117,476,526 (GRCm39) |
S327T |
probably benign |
Het |
| Zbtb4 |
T |
A |
11: 69,668,465 (GRCm39) |
M396K |
probably damaging |
Het |
| Zfp352 |
C |
T |
4: 90,113,246 (GRCm39) |
T462I |
possibly damaging |
Het |
| Zfp385b |
T |
C |
2: 77,307,189 (GRCm39) |
M145V |
probably damaging |
Het |
| Zfp780b |
C |
A |
7: 27,671,114 (GRCm39) |
V65F |
possibly damaging |
Het |
|
| Other mutations in Ddx60 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00340:Ddx60
|
APN |
8 |
62,411,680 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00915:Ddx60
|
APN |
8 |
62,440,465 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL00931:Ddx60
|
APN |
8 |
62,422,617 (GRCm39) |
missense |
probably benign |
0.18 |
|
IGL01023:Ddx60
|
APN |
8 |
62,395,548 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01313:Ddx60
|
APN |
8 |
62,435,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01615:Ddx60
|
APN |
8 |
62,416,774 (GRCm39) |
missense |
probably null |
0.81 |
|
IGL01733:Ddx60
|
APN |
8 |
62,436,899 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01779:Ddx60
|
APN |
8 |
62,470,857 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01900:Ddx60
|
APN |
8 |
62,453,743 (GRCm39) |
splice site |
probably benign |
|
|
IGL02110:Ddx60
|
APN |
8 |
62,470,281 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02302:Ddx60
|
APN |
8 |
62,428,866 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02468:Ddx60
|
APN |
8 |
62,411,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02569:Ddx60
|
APN |
8 |
62,477,985 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL02622:Ddx60
|
APN |
8 |
62,395,470 (GRCm39) |
splice site |
probably null |
|
|
IGL02657:Ddx60
|
APN |
8 |
62,437,149 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02677:Ddx60
|
APN |
8 |
62,441,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02701:Ddx60
|
APN |
8 |
62,432,375 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02806:Ddx60
|
APN |
8 |
62,409,156 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03137:Ddx60
|
APN |
8 |
62,441,117 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
IGL03295:Ddx60
|
APN |
8 |
62,409,155 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL03387:Ddx60
|
APN |
8 |
62,465,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03411:Ddx60
|
APN |
8 |
62,430,916 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Scatter
|
UTSW |
8 |
62,474,348 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
shotgun
|
UTSW |
8 |
62,490,101 (GRCm39) |
missense |
probably benign |
0.28 |
|
splay
|
UTSW |
8 |
62,474,343 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
G1Funyon:Ddx60
|
UTSW |
8 |
62,453,631 (GRCm39) |
missense |
probably benign |
0.01 |
|
PIT4504001:Ddx60
|
UTSW |
8 |
62,411,147 (GRCm39) |
missense |
probably benign |
|
|
PIT4677001:Ddx60
|
UTSW |
8 |
62,425,288 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0090:Ddx60
|
UTSW |
8 |
62,395,327 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0266:Ddx60
|
UTSW |
8 |
62,486,527 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0325:Ddx60
|
UTSW |
8 |
62,436,889 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0367:Ddx60
|
UTSW |
8 |
62,470,783 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R0479:Ddx60
|
UTSW |
8 |
62,422,691 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0561:Ddx60
|
UTSW |
8 |
62,470,828 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0844:Ddx60
|
UTSW |
8 |
62,440,395 (GRCm39) |
missense |
probably benign |
0.27 |
|
R1119:Ddx60
|
UTSW |
8 |
62,395,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1428:Ddx60
|
UTSW |
8 |
62,411,193 (GRCm39) |
splice site |
probably benign |
|
|
R1778:Ddx60
|
UTSW |
8 |
62,427,210 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1840:Ddx60
|
UTSW |
8 |
62,422,587 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1964:Ddx60
|
UTSW |
8 |
62,401,903 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1970:Ddx60
|
UTSW |
8 |
62,425,240 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2101:Ddx60
|
UTSW |
8 |
62,393,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2174:Ddx60
|
UTSW |
8 |
62,470,234 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2174:Ddx60
|
UTSW |
8 |
62,409,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2198:Ddx60
|
UTSW |
8 |
62,411,097 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2332:Ddx60
|
UTSW |
8 |
62,490,125 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2338:Ddx60
|
UTSW |
8 |
62,465,470 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R2379:Ddx60
|
UTSW |
8 |
62,490,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4010:Ddx60
|
UTSW |
8 |
62,409,178 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4010:Ddx60
|
UTSW |
8 |
62,407,569 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R4133:Ddx60
|
UTSW |
8 |
62,425,254 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4282:Ddx60
|
UTSW |
8 |
62,447,427 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4382:Ddx60
|
UTSW |
8 |
62,402,012 (GRCm39) |
splice site |
probably null |
|
|
R4561:Ddx60
|
UTSW |
8 |
62,395,495 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4572:Ddx60
|
UTSW |
8 |
62,440,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4581:Ddx60
|
UTSW |
8 |
62,476,295 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4635:Ddx60
|
UTSW |
8 |
62,490,101 (GRCm39) |
missense |
probably benign |
0.28 |
|
R4698:Ddx60
|
UTSW |
8 |
62,465,458 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4807:Ddx60
|
UTSW |
8 |
62,432,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4858:Ddx60
|
UTSW |
8 |
62,474,348 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R4964:Ddx60
|
UTSW |
8 |
62,432,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5120:Ddx60
|
UTSW |
8 |
62,398,940 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5187:Ddx60
|
UTSW |
8 |
62,427,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5222:Ddx60
|
UTSW |
8 |
62,437,192 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5400:Ddx60
|
UTSW |
8 |
62,463,036 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R5500:Ddx60
|
UTSW |
8 |
62,403,485 (GRCm39) |
missense |
probably benign |
0.28 |
|
R5514:Ddx60
|
UTSW |
8 |
62,411,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5668:Ddx60
|
UTSW |
8 |
62,453,612 (GRCm39) |
missense |
probably benign |
0.38 |
|
R5742:Ddx60
|
UTSW |
8 |
62,401,955 (GRCm39) |
missense |
probably benign |
|
|
R5772:Ddx60
|
UTSW |
8 |
62,401,931 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5810:Ddx60
|
UTSW |
8 |
62,465,422 (GRCm39) |
nonsense |
probably null |
|
|
R5815:Ddx60
|
UTSW |
8 |
62,416,756 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5820:Ddx60
|
UTSW |
8 |
62,409,155 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R5866:Ddx60
|
UTSW |
8 |
62,393,774 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5881:Ddx60
|
UTSW |
8 |
62,490,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5977:Ddx60
|
UTSW |
8 |
62,474,444 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6048:Ddx60
|
UTSW |
8 |
62,453,616 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6061:Ddx60
|
UTSW |
8 |
62,476,275 (GRCm39) |
missense |
probably null |
0.01 |
|
R6153:Ddx60
|
UTSW |
8 |
62,398,974 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R6287:Ddx60
|
UTSW |
8 |
62,403,612 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6415:Ddx60
|
UTSW |
8 |
62,436,939 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6416:Ddx60
|
UTSW |
8 |
62,451,715 (GRCm39) |
missense |
probably benign |
|
|
R6416:Ddx60
|
UTSW |
8 |
62,430,984 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6660:Ddx60
|
UTSW |
8 |
62,409,273 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6694:Ddx60
|
UTSW |
8 |
62,490,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6715:Ddx60
|
UTSW |
8 |
62,436,924 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6720:Ddx60
|
UTSW |
8 |
62,453,723 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6937:Ddx60
|
UTSW |
8 |
62,490,103 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7153:Ddx60
|
UTSW |
8 |
62,441,142 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7274:Ddx60
|
UTSW |
8 |
62,393,142 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7409:Ddx60
|
UTSW |
8 |
62,411,612 (GRCm39) |
missense |
probably benign |
0.24 |
|
R7464:Ddx60
|
UTSW |
8 |
62,393,708 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7670:Ddx60
|
UTSW |
8 |
62,428,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7904:Ddx60
|
UTSW |
8 |
62,430,924 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7992:Ddx60
|
UTSW |
8 |
62,407,569 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8124:Ddx60
|
UTSW |
8 |
62,436,945 (GRCm39) |
missense |
probably benign |
|
|
R8125:Ddx60
|
UTSW |
8 |
62,436,945 (GRCm39) |
missense |
probably benign |
|
|
R8126:Ddx60
|
UTSW |
8 |
62,436,945 (GRCm39) |
missense |
probably benign |
|
|
R8155:Ddx60
|
UTSW |
8 |
62,470,205 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R8174:Ddx60
|
UTSW |
8 |
62,470,284 (GRCm39) |
splice site |
probably null |
|
|
R8192:Ddx60
|
UTSW |
8 |
62,431,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8271:Ddx60
|
UTSW |
8 |
62,393,142 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8301:Ddx60
|
UTSW |
8 |
62,453,631 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8304:Ddx60
|
UTSW |
8 |
62,451,803 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R8319:Ddx60
|
UTSW |
8 |
62,395,669 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8374:Ddx60
|
UTSW |
8 |
62,427,205 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8401:Ddx60
|
UTSW |
8 |
62,409,277 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R8487:Ddx60
|
UTSW |
8 |
62,427,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8804:Ddx60
|
UTSW |
8 |
62,411,640 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8826:Ddx60
|
UTSW |
8 |
62,398,990 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8829:Ddx60
|
UTSW |
8 |
62,393,695 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8881:Ddx60
|
UTSW |
8 |
62,474,343 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8884:Ddx60
|
UTSW |
8 |
62,447,553 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R8990:Ddx60
|
UTSW |
8 |
62,427,168 (GRCm39) |
nonsense |
probably null |
|
|
R9122:Ddx60
|
UTSW |
8 |
62,442,898 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9225:Ddx60
|
UTSW |
8 |
62,470,875 (GRCm39) |
missense |
probably benign |
0.36 |
|
R9278:Ddx60
|
UTSW |
8 |
62,431,012 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9293:Ddx60
|
UTSW |
8 |
62,462,994 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9405:Ddx60
|
UTSW |
8 |
62,425,248 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9766:Ddx60
|
UTSW |
8 |
62,465,312 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0003:Ddx60
|
UTSW |
8 |
62,486,451 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
X0019:Ddx60
|
UTSW |
8 |
62,416,726 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1177:Ddx60
|
UTSW |
8 |
62,453,622 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- acACACAACCAGAACAGAGAGACTGA -3'
(R):5'- GCAGAACTACATGCTGAGAGCAATGA -3'
Sequencing Primer
(F):5'- GAATGTGCTGAAAATGCTTTCG -3'
(R):5'- TGCTGAGAGCAATGAGCTTCC -3'
|
| Posted On |
2014-07-08 |
Incidental Mutation